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Items: 1 to 20 of 53

1.
ApoER2-Dab1 disruption as the origin of pTau-associated neurodegeneration in sporadic Alzheimer’s disease
Christopher E. Ramsden, Daisy Zamora, Mark S. Horowitz, Jahandar Jahanipour, Elizabeth Calzada, Xiufeng Li, Gregory S. Keyes, Helen C. Murray, Maurice A. Curtis, Richard M. Faull, Andrea Sedlock, Dragan Maric
Acta Neuropathol Commun. 2023; 11: 197. Published online 2023 Dec 13. doi: 10.1186/s40478-023-01693-9
PMCID:
PMC10720169
AbstractArticlePDF–6.4M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
4.
Whole genome analysis in APOE4 homozygotes identifies the DAB1-RELN pathway in Alzheimer's disease pathogenesis
Matthew Bracher-Smith, Ganna Leonenko, Emily Baker, Karen Crawford, Andrew C. Graham, Dervis A. Salih, Brian W. Howell, John Hardy, Valentina Escott-Price
Neurobiol Aging. 2022 Nov; 119: 67–76. doi: 10.1016/j.neurobiolaging.2022.07.009
PMCID:
PMC9548409
AbstractArticle
5.
Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia
Carmela Ciardullo, Katarzyna Szoltysek, Peixun Zhou, Monika Pietrowska, Lukasz Marczak, Elaine Willmore, Amir Enshaei, Anna Walaszczyk, Jia Yee Ho, Vikki Rand, Scott Marshall, Andrew G. Hall, Christine J. Harrison, Meera Soundararajan, Jeyanthy Eswaran
Cancers (Basel) 2022 Jan; 14(1): 23. Published online 2021 Dec 21. doi: 10.3390/cancers14010023
PMCID:
PMC8750551
AbstractArticlePDF–2.8M
6.
Disabled 1 Is Part of a Signaling Pathway Activated by Epidermal Growth Factor Receptor
Paula Dlugosz, Magdalena Teufl, Maximilian Schwab, Katharina Eva Kohl, Johannes Nimpf
Int J Mol Sci. 2021 Feb; 22(4): 1745. Published online 2021 Feb 9. doi: 10.3390/ijms22041745
PMCID:
PMC7916142
AbstractArticlePDF–4.4M
7.
Inhibition of microRNA-300 inhibits cell adhesion, migration, and invasion of prostate cancer cells by promoting the expression of DAB1
Lin Li, Jing Hao, Cheng-Quan Yan, He-Feng Wang, Bin Meng, Sheng-Yong Cai
Cell Cycle. 2020; 19(21): 2793–2810. Published online 2020 Oct 16. doi: 10.1080/15384101.2020.1823730
PMCID:
PMC7714426
AbstractArticlePDF–2.1M
8.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
9.
Expression and localization of DAB1 and Reelin during normal human kidney development
Anita Racetin, Marija Jurić, Natalija Filipović, Ivana Šolić, Ivona Kosović, Merica Glavina Durdov, Nenad Kunac, Sandra Zekić Tomaš, Marijan Saraga, Violeta Šoljić, Vlatka Martinović, Joško Petričević, Ivana Restović, Valentina Lasić, Sandra Kostić, Boris Kablar, Koichiro Watanabe, Yu Katsuyama, Mirna Saraga Babić, Katarina Vukojević
Croat Med J. 2019 Dec; 60(6): 521–531. doi: 10.3325/cmj.2019.60.521
PMCID:
PMC6952895
AbstractArticlePDF–2.8M
10.
Disabled-1 Binds to the Cytoplasmic Domain of Amyloid Precursor-Like Protein 1
Ramin Homayouni, Dennis S. Rice, Michael Sheldon, Tom Curran
J Neurosci. 1999 Sep 1; 19(17): 7507–7515. doi: 10.1523/JNEUROSCI.19-17-07507.1999
PMCID:
PMC6782519
AbstractArticlePDF–633K
11.
Cyclin-Dependent Kinase 5 Phosphorylates Disabled 1 Independently of Reelin Signaling
Lakhu Keshvara, Susan Magdaleno, David Benhayon, Tom Curran
J Neurosci. 2002 Jun 15; 22(12): 4869–4877. doi: 10.1523/JNEUROSCI.22-12-04869.2002
PMCID:
PMC6757745
AbstractArticlePDF–700K
12.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
13.
The Central Fragment of Reelin, Generated by Proteolytic Processing In Vivo, Is Critical to Its Function during Cortical Plate Development
Yves Jossin, Nina Ignatova, Thomas Hiesberger, Joachim Herz, Catherine Lambert de Rouvroit, André M. Goffinet
J Neurosci. 2004 Jan 14; 24(2): 514–521. doi: 10.1523/JNEUROSCI.3408-03.2004
PMCID:
PMC6730001
AbstractArticlePDF–593K
14.
Functional Dissection of Reelin Signaling by Site-Directed Disruption of Disabled-1 Adaptor Binding to Apolipoprotein E Receptor 2: Distinct Roles in Development and Synaptic Plasticity
Uwe Beffert, Andre Durudas, Edwin J. Weeber, Peggy C. Stolt, Klaus M. Giehl, J. David Sweatt, Robert E. Hammer, Joachim Herz
J Neurosci. 2006 Feb 15; 26(7): 2041–2052. doi: 10.1523/JNEUROSCI.4566-05.2006
PMCID:
PMC6674917
AbstractArticlePDF–1.1M
15.
Disabled‐1 is down‐regulated in clinical breast cancer and regulates cell apoptosis through NF‐κB/Bcl‐2/caspase‐9
Rang‐Juan Cao, Kai Li, Wan‐Ying Xing, Shuang Du, Qiang Li, Xiao‐Juan Zhu, Shu‐Sen Cui
J Cell Mol Med. 2019 Feb; 23(2): 1622–1627. Published online 2018 Nov 28. doi: 10.1111/jcmm.14047
PMCID:
PMC6349202
AbstractArticlePDF–850K
16.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
AbstractArticlePDF–1.3M
17.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
18.
CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia
Qing-Yun Wu, Yuan-Yuan Zhu, Yang Liu, Fang Wei, Yu-Xue Tong, Jiang Cao, Ping Zhou, Ming-Shan Niu, Zhen-Yu Li, Ling-Yu Zeng, Feng Li, Kai-Lin Xu
Cell Death Dis. 2018 Jul; 9(7): 774. Published online 2018 Jul 10. doi: 10.1038/s41419-018-0812-6
PMCID:
PMC6039501
AbstractArticlePDF–2.7M
19.
A Pentanucleotide ATTTC Repeat Insertion in the Non-coding Region of DAB1, Mapping to SCA37, Causes Spinocerebellar Ataxia
Ana I. Seixas, Joana R. Loureiro, Cristina Costa, Andrés Ordóñez-Ugalde, Hugo Marcelino, Cláudia L. Oliveira, José L. Loureiro, Ashutosh Dhingra, Eva Brandão, Vitor T. Cruz, Angela Timóteo, Beatriz Quintáns, Guy A. Rouleau, Patrizia Rizzu, Ángel Carracedo, José Bessa, Peter Heutink, Jorge Sequeiros, Maria J. Sobrido, Paula Coutinho, Isabel Silveira
Am J Hum Genet. 2017 Jul 6; 101(1): 87–103. Published online 2017 Jul 6. doi: 10.1016/j.ajhg.2017.06.007
PMCID:
PMC5501871
AbstractArticlePDF–3.9M
20.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M

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