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Select item 115494491.

Psmb8 inhibits mitochondrial fission and alleviates myocardial ischaemia/reperfusion injury by targeting Drp1 degradation

Hui-Xiang Su, Luo-Luo Xu, Pang-Bo Li, Hai-Lian Bi, Wen-Xi Jiang, Hui-Hua Li

Cell Death Dis. 2024 Nov; 15(11): 803. Published online 2024 Nov 8. doi: 10.1038/s41419-024-07189-1

PMCID:: PMC11549449

Abstract Article PDF–6.8M

Select item 94039752.

Airway epithelial immunoproteasome subunit LMP7 protects against rhinovirus infection

Kris Genelyn Dimasuay, Niccolette Schaunaman, Bruce Berg, Diana Cervantes, Elke Kruger, Frank L. Heppner, Deborah A. Ferrington, Hong Wei Chu

Sci Rep. 2022; 12: 14507. Published online 2022 Aug 25. doi: 10.1038/s41598-022-18807-3

PMCID:: PMC9403975

Abstract Article PDF–1.3M

Select item 91973843.

Immunoproteasome Inhibition Reduces the T Helper 2 Response in Mouse Models of Allergic Airway Inflammation

Franziska Oliveri, Michael Basler, Tata Nageswara Rao, Hans Joerg Fehling, Marcus Groettrup

Front Immunol. 2022; 13: 870720. Published online 2022 May 30. doi: 10.3389/fimmu.2022.870720

PMCID:: PMC9197384

Abstract Article PDF–8.0M

Select item 85778494.

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

Soyeon Lim, You-Joung Kim, Sooyeon Park, Ji-heon Choi, Young Hoon Sung, Katsuhiko Nishimori, Zbynek Kozmik, Han-Woong Lee, Jin Woo Kim

eLife. 2021; 10: e70079. Published online 2021 Oct 22. doi: 10.7554/eLife.70079

PMCID:: PMC8577849

Abstract Article PDF–10M

Select item 80991505.

The Immunoproteasome Subunits LMP2, LMP7 and MECL-1 Are Crucial Along the Induction of Cerebral Toxoplasmosis

Timothy French, Nicole Israel, Henning Peter Düsedau, Anne Tersteegen, Johannes Steffen, Clemens Cammann, Eylin Topfstedt, Daniela Dieterich, Thomas Schüler, Ulrike Seifert, Ildiko Rita Dunay

Front Immunol. 2021; 12: 619465. Published online 2021 Apr 21. doi: 10.3389/fimmu.2021.619465

PMCID:: PMC8099150

Abstract Article PDF–3.6M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 77740617.

Immunosubunit β5i Knockout Suppresses Neovascularization and Restores Autophagy in Retinal Neovascularization by Targeting ATG5 for Degradation

Liyang Ji, Li Li, Ying Zhao, Shengqiang Liu, Jingmin Li, Jinsong Zhang, Qi Zhao, Shuai Wang

Invest Ophthalmol Vis Sci. 2020 Dec; 61(14): 30. Published online 2020 Dec 28. doi: 10.1167/iovs.61.14.30

PMCID:: PMC7774061

Abstract Article PDF–4.7M

Select item 70083738.

PITHD1 is a proteasome-interacting protein essential for male fertilization

Hiroyuki Kondo, Takafumi Matsumura, Mari Kaneko, Kenichi Inoue, Hidetaka Kosako, Masahito Ikawa, Yousuke Takahama, Izumi Ohigashi

J Biol Chem. 2020 Feb 7; 295(6): 1658–1672. Published online 2020 Jan 8. doi: 10.1074/jbc.RA119.011144

PMCID:: PMC7008373

Abstract Article PDF–2.9M

Select item 69538979.

Ablation of Immunoproteasome β5i Subunit Suppresses Hypertensive Retinopathy by Blocking ATRAP Degradation in Mice

Shuai Wang, Jing Li, Tong Wang, Jie Bai, Yun-Long Zhang, Qiu-Yue Lin, Jing-min Li, Qi Zhao, Shu-Bin Guo, Hui-Hua Li

Mol Ther. 2020 Jan 8; 28(1): 279–292. Published online 2019 Oct 5. doi: 10.1016/j.ymthe.2019.09.025

PMCID:: PMC6953897

Abstract Article PDF–4.5M

Select item 689749210.

Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells

Izumi Ohigashi, Yu Tanaka, Kenta Kondo, Sayumi Fujimori, Hiroyuki Kondo, Amy C. Palin, Victoria Hoffmann, Mina Kozai, Yosuke Matsushita, Shinsuke Uda, Ryo Motosugi, Jun Hamazaki, Hiroyuki Kubota, Shigeo Murata, Keiji Tanaka, Toyomasa Katagiri, Hidetaka Kosako, Yousuke Takahama

Cell Rep. Author manuscript; available in PMC 2019 Dec 6.

Published in final edited form as: Cell Rep. 2019 Nov 26; 29(9): 2901–2916.e6. doi: 10.1016/j.celrep.2019.10.079

PMCID:: PMC6897492

Abstract Article PDF–2.7M

Select item 677388911.

Fluctuations of Spleen Cytokine and Blood Lactate, Importance of Cellular Immunity in Host Defense Against Blood Stage Malaria Plasmodium yoelii

Takashi Imai, Kazutomo Suzue, Ha Ngo-Thanh, Suguri Ono, Wakako Orita, Haruka Suzuki, Chikako Shimokawa, Alex Olia, Seiji Obi, Tomoyo Taniguchi, Hidekazu Ishida, Luc Van Kaer, Shigeo Murata, Keiji Tanaka, Hajime Hisaeda

Front Immunol. 2019; 10: 2207. Published online 2019 Sep 25. doi: 10.3389/fimmu.2019.02207

PMCID:: PMC6773889

Abstract Article PDF–1.9M

Select item 650624412.

The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation

Xin Xie, Hai-Lian Bi, Song Lai, Yun-Long Zhang, Nan Li, Hua-Jun Cao, Ling Han, Hong-Xia Wang, Hui-Hua Li

Sci Adv. 2019 May; 5(5): eaau0495. Published online 2019 May 8. doi: 10.1126/sciadv.aau0495

PMCID:: PMC6506244

Abstract Article PDF–10M

Select item 628079613.

Co‐inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity

Michael Basler, Michelle M Lindstrom, Jacob J LaStant, J Michael Bradshaw, Timothy D Owens, Christian Schmidt, Elmer Maurits, Christopher Tsu, Herman S Overkleeft, Christopher J Kirk, Claire L Langrish, Marcus Groettrup

EMBO Rep. 2018 Dec; 19(12): e46512. Published online 2018 Oct 2. doi: 10.15252/embr.201846512

PMCID:: PMC6280796

Abstract Article PDF–1.2M

Select item 602144514.

mTORC1 accelerates retinal development via the immunoproteasome

Ji-Heon Choi, Hong Seok Jo, Soyeon Lim, Hyoung-Tai Kim, Kang Woo Lee, Kyeong Hwan Moon, Taejeong Ha, Sang Soo Kwak, Yeha Kim, Eun Jung Lee, Cheol O. Joe, Jin Woo Kim

Nat Commun. 2018; 9: 2502. Published online 2018 Jun 27. doi: 10.1038/s41467-018-04774-9

PMCID:: PMC6021445

Abstract Article PDF–8.3M

Select item 601406115.

Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders

Scott Ugras, Malcolm J. Daniels, Hossein Fazelinia, Neal S. Gould, Anastasia K. Yocum, Kelvin C. Luk, Esteban Luna, Hua Ding, Chris McKennan, Steven Seeholzer, Dan Martinez, Perry Evans, Daniel Brown, John E. Duda, Harry Ischiropoulos

EBioMedicine. 2018 May; 31: 307–319. Published online 2018 May 24. doi: 10.1016/j.ebiom.2018.05.007

PMCID:: PMC6014061

Abstract Article PDF–3.5M

Select item 564540116.

Immunoproteasome subunit ß5i/LMP7-deficiency in atherosclerosis

Bernd Hewing, Antje Ludwig, Cristian Dan, Max Pötzsch, Carmen Hannemann, Andreas Petry, Dilyara Lauer, Agnes Görlach, Elena Kaschina, Dominik N. Müller, Gert Baumann, Verena Stangl, Karl Stangl, Nicola Wilck

Sci Rep. 2017; 7: 13342. Published online 2017 Oct 17. doi: 10.1038/s41598-017-13592-w

PMCID:: PMC5645401

Abstract Article PDF–1.9M

Select item 558421217.

Inhibition and deficiency of the immunoproteasome subunit LMP7 suppress the development and progression of colorectal carcinoma in mice

Julia Koerner, Thomas Brunner, Marcus Groettrup

Oncotarget. 2017 Aug 1; 8(31): 50873–50888. Published online 2017 Feb 7. doi: 10.18632/oncotarget.15141

PMCID:: PMC5584212

Abstract Article PDF–5.7M

Select item 534437718.

PA28 modulates antigen processing and viral replication during coxsackievirus B3 infection

Dorota Respondek, Martin Voss, Ina Kühlewindt, Karin Klingel, Elke Krüger, Antje Beling

PLoS One. 2017; 12(3): e0173259. Published online 2017 Mar 9. doi: 10.1371/journal.pone.0173259

PMCID:: PMC5344377

Abstract Article PDF–2.1M

Select item 515808719.

Peptide Processing Is Critical for T-Cell Memory Inflation and May Be Optimized to Improve Immune Protection by CMV-Based Vaccine Vectors

Iryna Dekhtiarenko, Robert B. Ratts, Renata Blatnik, Lian N. Lee, Sonja Fischer, Lisa Borkner, Jennifer D. Oduro, Thomas F. Marandu, Stephanie Hoppe, Zsolt Ruzsics, Julia K. Sonnemann, Mandana Mansouri, Christine Meyer, Niels A. W. Lemmermann, Rafaela Holtappels, Ramon Arens, Paul Klenerman, Klaus Früh, Matthias J. Reddehase, Angelika B. Riemer, Luka Cicin-Sain

PLoS Pathog. 2016 Dec; 12(12): e1006072. Published online 2016 Dec 15. doi: 10.1371/journal.ppat.1006072

PMCID:: PMC5158087

Abstract Article PDF–4.3M

Select item 511978620.

Denervation-Induced Activation of the Standard Proteasome and Immunoproteasome

Haiming M. Liu, Deborah A. Ferrington, Cory W. Baumann, LaDora V. Thompson

PLoS One. 2016; 11(11): e0166831. Published online 2016 Nov 22. doi: 10.1371/journal.pone.0166831

PMCID:: PMC5119786

Abstract Article PDF–1.7M

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