PMC Links for GEO Profiles (Select 77151055) - PMC

Jaya Lakshmi Thangaraj, Minh-Trang Thi Phan, SoonHo Kweon, Jinho Kim, Jong-Min Lee, Ilwoong Hwang, Jeehun Park, Junsang Doh, Seung-Hwan Lee, Manh-Cuong Vo, Tan-Huy Chu, Ga-Young Song, Seo-Yeon Ahn, Sung-Hoon Jung, Hyeoung-Joon Kim, Duck Cho, Je-Jung Lee

Cancer Immunol Immunother. 2022 Mar; 71(3): 613–625. Published online 2021 Jul 20. doi: 10.1007/s00262-021-02982-9

PMCID:: PMC10991462

Abstract Article PDF–840K

Select item 105948094.

Interleukin-21 modulates balance between regulatory T cells and T-helper 17 cells in chronic hepatitis B virus infection

Yun Cai, Hailei Ji, Xin Zhou, Kai Zhao, Xiaoping Zhang, Liang Pan, Ruihua Shi

BMC Infect Dis. 2023; 23: 719. Published online 2023 Oct 24. doi: 10.1186/s12879-023-08723-w

PMCID:: PMC10594809

Abstract Article PDF–1.6M

Select item 105268365.

Interleukin-21 Influences Glioblastoma Course: Biological Mechanisms and Therapeutic Potential

Alberto Repici, Alessio Ardizzone, Alessia Filippone, Cristina Colarossi, Marzia Mare, Gabriele Raciti, Deborah Mannino, Salvatore Cuzzocrea, Irene Paterniti, Emanuela Esposito

Cells. 2023 Sep; 12(18): 2284. Published online 2023 Sep 15. doi: 10.3390/cells12182284

PMCID:: PMC10526836

Abstract Article PDF–739K

Select item 105262286.

Interaction of S100A6 Protein with the Four-Helical Cytokines

Alexey S. Kazakov, Evgenia I. Deryusheva, Victoria A. Rastrygina, Andrey S. Sokolov, Maria E. Permyakova, Ekaterina A. Litus, Vladimir N. Uversky, Eugene A. Permyakov, Sergei E. Permyakov

Biomolecules. 2023 Sep; 13(9): 1345. Published online 2023 Sep 4. doi: 10.3390/biom13091345

PMCID:: PMC10526228

Abstract Article PDF–13M

Select item 105248587.

Interleukin-21 promotes Type-1 activation and cytotoxicity of CD56^dimCD16^bright natural killer cells during kidney allograft antibody-mediated rejection showing a new link between adaptive and innate humoral allo-immunity

Elodie Bailly, Camila Macedo, Jason Ossart, Kevin Louis, Xinyan Gu, Bala Ramaswami, Carol Bentlejewski, Adriana Zeevi, Parmjeet Randhawa, Carmen Lefaucheur, Diana Metes

Kidney Int. Author manuscript; available in PMC 2024 Oct 1.

Published in final edited form as: Kidney Int. 2023 Oct; 104(4): 707–723. Published online 2023 May 21. doi: 10.1016/j.kint.2023.04.024

PMCID:: PMC10524858

Abstract Article PDF–3.2M

Select item 104548458.

T Follicular Helper Cells in Tertiary Lymphoid Structure Contribute to Renal Fibrosis by IL-21

Ran Luo, Dan Chang, Nanhui Zhang, Yichun Cheng, Shuwang Ge, Gang Xu

Int J Mol Sci. 2023 Aug; 24(16): 12535. Published online 2023 Aug 8. doi: 10.3390/ijms241612535

PMCID:: PMC10454845

Abstract Article PDF–11M

Select item 103217559.

Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression

Anna-Mari Schroderus, Josh Poorbaugh, Samantha McElyea, Stephanie Beasley, Lin Zhang, Kirsti Näntö-Salonen, Reeta Rintamäki, Jussi Pihlajamäki, Mikael Knip, Riitta Veijola, Jorma Toppari, Jorma Ilonen, Robert J. Benschop, Tuure Kinnunen

Front Immunol. 2023; 14: 1157265. Published online 2023 Jun 21. doi: 10.3389/fimmu.2023.1157265

PMCID:: PMC10321755

Abstract Article PDF–2.6M

Select item 1032083010.

A structural blueprint for interleukin-21 signal modulation

Gita C. Abhiraman, Theodora U.J. Bruun, Nathanael A. Caveney, Leon L. Su, Robert A. Saxton, Qian Yin, Shaogeng Tang, Mark M. Davis, Kevin M. Jude, K. Christopher Garcia

Cell Rep. 2023 Jun 27; 42(6): 112657. Published online 2023 Jun 19. doi: 10.1016/j.celrep.2023.112657

PMCID:: PMC10320830

Abstract Article PDF–5.4M

Select item 1022786211.

Clonally-Expanded, Thyrotoxic Effector CD8⁺ T cells Driven by IL-21 Contribute to Checkpoint Inhibitor Thyroiditis

Melissa G. Lechner, Zikang Zhou, Aline T. Hoang, Nicole Huang, Jessica Ortega, Lauren N. Scott, Ho-Chung Chen, Anushi Y. Patel, Rana Yakhshi-Tafti, Kristy Kim, Willy Hugo, Pouyan Famini, Alexandra Drakaki, Antoni Ribas, Trevor E. Angell, Maureen A. Su

Sci Transl Med. Author manuscript; available in PMC 2023 Nov 17.

Published in final edited form as: Sci Transl Med. 2023 May 17; 15(696): eadg0675. Published online 2023 May 17. doi: 10.1126/scitranslmed.adg0675

PMCID:: PMC10227862

Abstract Article PDF–2.1M

Select item 1013778112.

IL-21 (rs2055979 and rs2221903)/IL-21R (rs3093301) Polymorphism and High Levels of IL-21 Are Associated with Rheumatoid Arthritis in Mexican Patients

Noemi Magdalena Carreño-Saavedra, Itzel Viridiana Reyes-Pérez, Andrea Carolina Machado-Sulbaran, Gloria Esther Martínez-Bonilla, María Guadalupe Ramírez-Dueñas, José Francisco Muñoz-Valle, Valeria Olaya-Valdiviezo, Trinidad García-Iglesias, Erika Aurora Martínez-García, Pedro Ernesto Sánchez-Hernández

Genes (Basel) 2023 Apr; 14(4): 878. Published online 2023 Apr 7. doi: 10.3390/genes14040878

PMCID:: PMC10137781

Abstract Article PDF–904K

Select item 972925113.

In patients with primary Sjögren’s syndrome innate-like MAIT cells display upregulated IL-7R, IFN-γ, and IL-21 expression and have increased proportions of CCR9 and CXCR5-expressing cells

Anneline C. Hinrichs, Aike A. Kruize, Helen L. Leavis, Joel A. G. van Roon

Front Immunol. 2022; 13: 1017157. Published online 2022 Nov 24. doi: 10.3389/fimmu.2022.1017157

PMCID:: PMC9729251

Abstract Article PDF–8.1M

Select item 956999014.

Calcium-Bound S100P Protein Is a Promiscuous Binding Partner of the Four-Helical Cytokines

Alexey S. Kazakov, Evgenia I. Deryusheva, Maria E. Permyakova, Andrey S. Sokolov, Victoria A. Rastrygina, Vladimir N. Uversky, Eugene A. Permyakov, Sergei E. Permyakov

Int J Mol Sci. 2022 Oct; 23(19): 12000. Published online 2022 Oct 9. doi: 10.3390/ijms231912000

PMCID:: PMC9569990

Abstract Article PDF–3.2M

Select item 932615315.

Interleukins 4 and 21 Protect Anti-IgM Induced Cell Death in Ramos B Cells: Implication for Autoimmune Diseases

Chin Wai Hui, Wai Chung Wu, Shui On Leung

Front Immunol. 2022; 13: 919854. Published online 2022 Jul 13. doi: 10.3389/fimmu.2022.919854

PMCID:: PMC9326153

Abstract Article PDF–11M

Select item 928864016.

Impact of IL-21 Gene Polymorphisms (rs2055979) and the Levels of Serum IL-21 on the Risk of Multiple Sclerosis

Ali Abdulla A, Abdulaali Abed T, Razzaq Abdul-Ameer W

Arch Razi Inst. 2022 Feb; 77(1): 81–86. Published online 2022 Feb 28. doi: 10.22092/ARI.2021.356470.1848

PMCID:: PMC9288640

Abstract Article PDF–364K

Select item 916013117.

Impact of IL-21-associated peripheral and brain crosstalk on the Alzheimer’s disease neuropathology

Sudhanshu Agrawal, Janet E. Baulch, Shreya Madan, Seher Salah, Samantha N. Cheeks, Robert P. Krattli, Jr., Veedamali S. Subramanian, Munjal M. Acharya, Anshu Agrawal

Cell Mol Life Sci. 2022 Jun; 79(6): 331. Published online 2022 Jun 1. doi: 10.1007/s00018-022-04347-6

PMCID:: PMC9160131

Abstract Article PDF–3.2M

Select item 807978218.

Peripheral TIGIT+ T Follicular Helper Cells That Produce High Levels of Interleukin-21 via OX40 Represent Disease Activity in IgG4-Related Disease

Mitsuhiro Akiyama, Katsuya Suzuki, Keiko Yoshimoto, Hidekata Yasuoka, Yuko Kaneko, Tsutomu Takeuchi

Front Immunol. 2021; 12: 651357. Published online 2021 Apr 14. doi: 10.3389/fimmu.2021.651357

PMCID:: PMC8079782

Abstract Article PDF–3.1M

Select item 801730319.

Human PD-1^hiCD8⁺ T Cells Are a Cellular Source of IL-21 in Rheumatoid Arthritis

Kazuhiko Higashioka, Motoki Yoshimura, Takahide Sakuragi, Masahiro Ayano, Yasutaka Kimoto, Hiroki Mitoma, Nobuyuki Ono, Yojiro Arinobu, Makoto Kikukawa, Hisakata Yamada, Takahiko Horiuchi, Koichi Akashi, Hiroaki Niiro

Front Immunol. 2021; 12: 654623. Published online 2021 Mar 19. doi: 10.3389/fimmu.2021.654623

PMCID:: PMC8017303

Abstract Article PDF–2.6M

Select item 793649520.

Plasma interleukin-21 levels and genetic variants are associated with susceptibility to rheumatoid arthritis

Youguo Hao, Lijun Xie, Jing Xia, Zhen Liu, Baoxiu Yang, Minqin Zhang

BMC Musculoskelet Disord. 2021; 22: 246. Published online 2021 Mar 5. doi: 10.1186/s12891-021-04111-0

PMCID:: PMC7936495

Abstract Article PDF–847K

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