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Select item 112796161.

A Dynamic and Effective Peptide-Based Strategy for Promptly Addressing Emerging SARS-CoV-2 Variants of Concern

Michela Murdocca, Isabella Romeo, Gennaro Citro, Andrea Latini, Federica Centofanti, Antonella Bugatti, Francesca Caccuri, Arnaldo Caruso, Francesco Ortuso, Stefano Alcaro, Federica Sangiuolo, Giuseppe Novelli

Pharmaceuticals (Basel) 2024 Jul; 17(7): 891. Published online 2024 Jul 4. doi: 10.3390/ph17070891

PMCID:: PMC11279616

Abstract Article PDF–3.0M

Select item 112652802.

Dipeptidyl peptidase 4 interacts with porcine coronavirus PHEV spikes and mediates host range expansion

Junchao Shi, Shiyu Hu, Hanlu Wei, Le Zhang, Yungang Lan, Jiyu Guan, Kui Zhao, Feng Gao, Wenqi He, Zi Li

J Virol. 2024 Jul; 98(7): e00753-24. Published online 2024 Jun 3. doi: 10.1128/jvi.00753-24

PMCID:: PMC11265280

Abstract Article PDF–3.0M

Select item 111586813.

The expression of dipeptidyl peptidase IV (DPPIV/CD26) is associated with enhanced chemosensitivity to paclitaxel in epithelial ovarian carcinoma cells

Hiroaki Kajiyama, Kiyosumi Shibata, Kazuhiko Ino, Shigehiko Mizutani, Akihiro Nawa, Fumitaka Kikkawa

Cancer Sci. 2010 Feb; 101(2): 347–354. Published online 2009 Oct 3. doi: 10.1111/j.1349-7006.2009.01378.x

PMCID:: PMC11158681

Abstract Article PDF–1.0M

Select item 111428054.

Exploring the conformational dynamics and key amino acids in the CD26-caveolin-1 interaction and potential therapeutic interventions

Xiaopeng Hu, Chunmei Jiang, Yanli Gu, Xingkui Xue

Medicine (Baltimore) 2024 May 31; 103(22): e38367. Published online 2024 May 31. doi: 10.1097/MD.0000000000038367

PMCID:: PMC11142805

Abstract Article PDF–2.5M

Select item 111047945.

Degranulation of human cytotoxic lymphocytes is a major source of proteolytically active soluble CD26/DPP4

Marcus Lettau, Michelle Dietz, Sarah Vollmers, Fred Armbrust, Christian Peters, Thi Mai Dang, Guranda Chitadze, Dieter Kabelitz, Ottmar Janssen

Cell Mol Life Sci. 2020 Feb; 77(4): 751–764. Published online 2019 Jul 12. doi: 10.1007/s00018-019-03207-0

PMCID:: PMC11104794

Abstract Article PDF–1.4M

Select item 110994866.

Increased Thyroid DPP4 Expression Is Associated With Inflammatory Process in Patients With Hashimoto Thyroiditis

Xiaohui Wen, Xiaona Chang, Xueqing He, Qingyun Cai, Guang Wang, Jia Liu

J Clin Endocrinol Metab. 2024 Jun; 109(6): 1517–1525. Published online 2023 Dec 21. doi: 10.1210/clinem/dgad723

PMCID:: PMC11099486

Abstract Article

Select item 110955497.

Interleukin 13–Induced Inflammation Increases DPP4 Abundance but Does Not Enhance Middle East Respiratory Syndrome Coronavirus Replication in Airway Epithelia

Kun Li, Jennifer A Bartlett, Christine L Wohlford-Lenane, Biyun Xue, Andrew L Thurman, Thomas M Gallagher, Alejandro A Pezzulo, Paul B McCray, Jr

J Infect Dis. 2024 May 15; 229(5): 1419–1429. Published online 2023 Sep 12. doi: 10.1093/infdis/jiad383

PMCID:: PMC11095549

Abstract Article PDF–8.3M

Select item 110811728.

Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection

Stefanie Deinhardt-Emmer, Sharvari Deshpande, Koji Kitazawa, Allison B. Herman, Joanna Bons, Jacob P. Rose, Prasanna Ashok Kumar, Carlos Anerillas, Francesco Neri, Serban Ciotlos, Kevin Perez, Nilay Köse-Vogel, Antje Häder, Kotb Abdelmohsen, Bettina Löffler, Myriam Gorospe, Pierre-Yves Desprez, Simon Melov, David Furman, Birgit Schilling, Judith Campisi

Aging Dis. 2024 May 7; 15(3): 1398–1415. Published online 2024 May 7. doi: 10.14336/AD.2023.0812

PMCID:: PMC11081172

Abstract Article PDF–1.3M

Select item 110207539.

Contribution of amino acids in the active site of dipeptidyl peptidase 4 to the catalytic action of the enzyme

Kathrin Gnoth, Joachim Wolfgang Bär, Fred Rosche, Jens-Ulrich Rahfeld, Hans-Ulrich Demuth

PLoS One. 2024; 19(4): e0289239. Published online 2024 Apr 16. doi: 10.1371/journal.pone.0289239

PMCID:: PMC11020753

Abstract Article PDF–795K

Select item 1085518510.

Association of DPP-4 Concentrations with the Occurrence of Gestational Diabetes Mellitus and Excessive Gestational Weight Gain

Magdalena Niebrzydowska-Tatus, Aleksandra Pełech, Katarzyna Bień, Julia Mekler, Miracle Santiago, Żaneta Kimber-Trojnar, Marcin Trojnar

Int J Mol Sci. 2024 Feb; 25(3): 1829. Published online 2024 Feb 2. doi: 10.3390/ijms25031829

PMCID:: PMC10855185

Abstract Article PDF–1.3M

Select item 1070763311.

VEGFR and DPP-IV as Markers of Severe COVID-19 and Predictors of ICU Admission

Ewa Pius-Sadowska, Piotr Kulig, Anna Niedźwiedź, Bartłomiej Baumert, Karolina Łuczkowska, Dorota Rogińska, Anna Sobuś, Zofia Ulańczyk, Miłosz Kawa, Edyta Paczkowska, Miłosz Parczewski, Anna Machalińska, Bogusław Machaliński

Int J Mol Sci. 2023 Dec; 24(23): 17003. Published online 2023 Nov 30. doi: 10.3390/ijms242317003

PMCID:: PMC10707633

Abstract Article PDF–2.3M

Select item 1046865812.

Genetic variants of dipeptidyl peptidase IV are linked to the clinicopathologic development of prostate cancer

Yu‐Ching Wen, Chia‐Yen Lin, Chi‐Hao Hsiao, Shian‐Shiang Wang, Hsiang‐Ching Huang, Yung‐Wei Lin, Kuo‐Hao Ho, Lun‐Ching Chang, Shun‐Fa Yang, Ming‐Hsien Chien

J Cell Mol Med. 2023 Sep; 27(17): 2507–2516. Published online 2023 Aug 2. doi: 10.1111/jcmm.17845

PMCID:: PMC10468658

Abstract Article PDF–1.0M

Select item 1043257713.

Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells

Chen Wang, Ravi Nistala, Min Cao, Yi Pan, Madelaine Behrens, Donald Doll, Richard D. Hammer, Puja Nistala, Hui-Ming Chang, Edward T.H. Yeh, XunLei Kang

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Feb 28; 42(2): 112105. Published online 2023 Feb 17. doi: 10.1016/j.celrep.2023.112105

PMCID:: PMC10432577

Abstract Article PDF–2.5M

Select item 1031375114.

Dipeptidyl-Peptidase 4 (CD26) is Associated with Chondrocyte Senescence and Radiographic Progression in Knee Osteoarthritis

Yu-Hsiu Chen, Xin Zhang, Ching-Heng Chou, Ming-Feng Hsueh, David Attarian, Yi-Ju Li, Virginia Byers Kraus

Arthritis Rheumatol. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Arthritis Rheumatol. 2023 Jul; 75(7): 1120–1131. Published online 2023 Apr 23. doi: 10.1002/art.42455

PMCID:: PMC10313751

Abstract Article PDF–1.4M

Select item 1029365315.

Targeting DPP4-RBD interactions by sitagliptin and linagliptin delivers a potential host-directed therapy against pan-SARS-CoV-2 infections

Shailendra Mani, Anupamjeet Kaur, Kamini Jakhar, Geetika Kumari, Sudipta Sonar, Amit Kumar, Sudesna Das, Santosh Kumar, Vijay Kumar, Rakesh Kundu, Anil Kumar Pandey, Umesh Prasad Singh, Tanmay Majumdar

Int J Biol Macromol. 2023 Aug 1; 245: 125444. Published online 2023 Jun 27. doi: 10.1016/j.ijbiomac.2023.125444

PMCID:: PMC10293653

Abstract Article PDF–13M

Select item 1026335616.

DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner

Madison S. Strine, Wesley L. Cai, Jin Wei, Mia Madel Alfajaro, Renata B. Filler, Scott B. Biering, Sylvia Sarnik, Ryan D. Chow, Ajinkya Patil, Kasey S. Cervantes, Clayton K. Collings, Peter C. DeWeirdt, Ruth E. Hanna, Kevin Schofield, Christopher Hulme, Silvana Konermann, John G. Doench, Patrick D. Hsu, Cigall Kadoch, Qin Yan, Craig B. Wilen

PLoS Biol. 2023 Jun; 21(6): e3002097. Published online 2023 Jun 13. doi: 10.1371/journal.pbio.3002097

PMCID:: PMC10263356

Abstract Article PDF–2.6M

Select item 1017868717.

The Combination of Natural Molecules Naringenin, Hesperetin, Curcumin, Polydatin and Quercetin Synergistically Decreases SEMA3E Expression Levels and DPPIV Activity in In Vitro Models of Insulin Resistance

Emanuele-Salvatore Scarpa, Chiara Giordani, Antonella Antonelli, Massimiliano Petrelli, Giancarlo Balercia, Francesca Silvetti, Alessio Pieroni, Jacopo Sabbatinelli, Maria Rita Rippo, Fabiola Olivieri, Giulia Matacchione

Int J Mol Sci. 2023 May; 24(9): 8071. Published online 2023 Apr 29. doi: 10.3390/ijms24098071

PMCID:: PMC10178687

Abstract Article PDF–3.0M

Select item 1016572418.

DPP4⁺ exosomes in AML patients’ plasma suppress proliferation of hematopoietic progenitor cells

Swathi Namburi, Hal E. Broxmeyer, Chang-Sook Hong, Theresa L. Whiteside, Michael Boyiadzis

Leukemia. Author manuscript; available in PMC 2023 May 8.

Published in final edited form as: Leukemia. 2021 Jul; 35(7): 1925–1932. Published online 2020 Nov 2. doi: 10.1038/s41375-020-01047-7

PMCID:: PMC10165724

Abstract Article PDF–959K

Select item 1011927019.

HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility

Xiaohan Cui, Xiao Yun, Meiling Sun, Renzhi Li, Xiajie Lyu, Yuanxiang Lao, Xihu Qin, Wenbin Yu

Hepatol Int. 2023 Apr; 17(2): 377–392. Published online 2022 Dec 12. doi: 10.1007/s12072-022-10459-9

Correction in:: Hepatol Int. 2023 Apr; 17(2): 516.

PMCID:: PMC10119270

Abstract Article PDF–9.0M

Select item 1010712520.

Distinct T cell subsets in adipose tissue are associated with obesity

Martha E. Haugstøyl, Martin Cornillet, Kristina Strand, Natalie Stiglund, Dan Sun, Laurence Lawrence‐Archer, Iren D. Hjellestad, Ernesto Sparrelid, Christian Busch, Jøran Hjelmesæth, Jens K. Hertel, Andrea Ponzetta, Gunnar Mellgren, Johan Fernø, Niklas K. Björkström

Eur J Immunol. 2023 Feb; 53(2): 2249990. Published online 2022 Dec 13. doi: 10.1002/eji.202249990

PMCID:: PMC10107125

Abstract Article PDF–2.2M

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