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Select item 92927991.

Cripto favors chondrocyte hypertrophy via TGF‐β SMAD1/5 signaling during development of osteoarthritis

Amaya Garcia de Vinuesa, Gonzalo Sanchez‐Duffhues, Esmeralda Blaney‐Davidson, Arjan van Caam, Kirsten Lodder, Yolande Ramos, Margreet Kloppenburg, Ingrid Meulenbelt, Peter van der Kraan, Marie‐José Goumans, Peter ten Dijke

J Pathol. 2021 Nov; 255(3): 330–342. Published online 2021 Sep 6. doi: 10.1002/path.5774

PMCID:: PMC9292799

Abstract Article PDF–20M

Select item 90126322.

CRIPTO-1 Is Immunolocalized in the Syncytiotrophoblast of Ampullary Pregnancies

Fábio Roberto Cabar, Pedro Paulo Pereira, Carla Letícia Bandeira, Estela Bevilacqua, Regina Schultz, Rossana Pulcineli Vieira Francisco

Biomed Res Int. 2022; 2022: 4769790. Published online 2022 Apr 8. doi: 10.1155/2022/4769790

PMCID:: PMC9012632

Abstract Article PDF–2.4M

Select item 86997993.

Oncofetal Protein CRIPTO Is Involved in Wound Healing and Fibrogenesis in the Regenerating Liver and Is Associated with the Initial Stages of Cardiac Fibrosis

Sofia Karkampouna, Danny van der Helm, Mario Scarpa, Bart van Hoek, Hein W. Verspaget, Marie-Jose Goumans, Minneke J. Coenraad, Boudewijn P.T. Kruithof, Marianna Kruithof-de Julio

Cells. 2021 Dec; 10(12): 3325. Published online 2021 Nov 26. doi: 10.3390/cells10123325

PMCID:: PMC8699799

Abstract Article PDF–6.1M

Select item 84575854.

Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways

Yu Liu, Yan-Qing Li, Shi-Hao Huang, Yong-Long Li, Jia-Wei Xia, Jun-Shuang Jia, Fang Wei, Jia-Hong Wang, Guan-Qi Dai, Yu-Cai Wang, Xiao-Yan Li, Liu-Xin Han, Xiao-Ling Zhang, Xu-Dong Xiang, Wen-Tao Zhao, Dong Xiao, Xiao-Lin Lin

Aging (Albany NY) 2021 Sep 15; 13(17): 21155–21190. Published online 2021 Sep 13. doi: 10.18632/aging.203402

PMCID:: PMC8457585

Abstract Article PDF–3.3M

Select item 84306855.

Cripto-1 as a Key Factor in Tumor Progression, Epithelial to Mesenchymal Transition and Cancer Stem Cells

Hilal Arnouk, Gloria Yum, Dean Shah

Int J Mol Sci. 2021 Sep; 22(17): 9280. Published online 2021 Aug 27. doi: 10.3390/ijms22179280

PMCID:: PMC8430685

Abstract Article PDF–1.0M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80571107.

High cripto-1 and low miR-205 expression levels as prognostic markers in early stage non-small cell lung cancer

Kang-Seo Park, Yong Wha Moon, Mark Raffeld, Dae Ho Lee, Yisong Wang, Giuseppe Giaccone

Lung Cancer. Author manuscript; available in PMC 2021 Apr 20.

Published in final edited form as: Lung Cancer. 2018 Feb; 116: 38–45. Published online 2017 Dec 15. doi: 10.1016/j.lungcan.2017.12.010

PMCID:: PMC8057110

Abstract Article PDF–802K

Select item 80292908.

Cripto‐1 Expression in Glioblastoma Multiforme

Linda Pilgaard, Joachim Høg Mortensen, Michael Henriksen, Pia Olesen, Preben Sørensen, Rene Laursen, Mogens Vyberg, Ralf Agger, Vladimir Zachar, Torben Moos, Meg Duroux

Brain Pathol. 2014 Jul; 24(4): 360–370. Published online 2014 Mar 28. doi: 10.1111/bpa.12131

PMCID:: PMC8029290

Abstract Article PDF–1.0M

Select item 77586369.

E2A regulates neural ectoderm fate specification in human embryonic stem cells

Siqi Yi, Xiaotian Huang, Shixin Zhou, Yuan Zhou, Michele K. Anderson, Juan Carlos Zúñiga-Pflücker, Qingxian Luan, Yang Li

Development. 2020 Dec 1; 147(23): dev190298. Published online 2020 Dec 13. doi: 10.1242/dev.190298

PMCID:: PMC7758636

Abstract Article

Select item 671262110.

Cripto-1 expression in patients with clear cell renal cell carcinoma is associated with poor disease outcome

Yi-Jun Xue, Song-Ning Chen, Wei-Guang Chen, Geng-Qing Wu, Yun-Feng Liao, Jian-Bin Xu, Hao Tang, Shui-Hua Yang, Shui-Yong He, Yun-Fei Luo, Zhi-Hui Wu, Hai-Wen Huang

J Exp Clin Cancer Res. 2019; 38: 378. Published online 2019 Aug 27. doi: 10.1186/s13046-019-1386-6

PMCID:: PMC6712621

Abstract Article PDF–2.9M

Select item 655544511.

Beneficial effects of Cripto-1 for transarterial chemoembolization in hepatocellular carcinoma

Xiao-shan Li, Jia-hong Wang, Xian-zi Yang, Lei Ma, Yan-xia Shi, Ye Song, Peng Jiang, Sha Gao, Ye Dong, Jin-rong Lin, Chuan Jin

Aging (Albany NY) 2019 May 31; 11(10): 2998–3011. Published online 2019 May 27. doi: 10.18632/aging.101951

PMCID:: PMC6555445

Abstract Article PDF–2.9M

Select item 627484412.

Exogenous Cripto-1 Suppresses Self-Renewal of Cancer Stem Cell Model

Md Jahangir Alam, Ryota Takahashi, Said M. Afify, Aung Ko Ko Oo, Kazuki Kumon, Hend M. Nawara, Aprilliana Cahya Khayrani, Juan Du, Maram H. Zahra, Akimasa Seno, David S. Salomon, Masaharu Seno

Int J Mol Sci. 2018 Nov; 19(11): 3345. Published online 2018 Oct 26. doi: 10.3390/ijms19113345

PMCID:: PMC6274844

Abstract Article PDF–3.0M

Select item 611323913.

Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/β-catenin pathway

Regina Cheuk-Lam Lo, Carmen Oi-Ning Leung, Kristy Kwan-Shuen Chan, Daniel Wai-Hung Ho, Chun-Ming Wong, Terence Kin-Wah Lee, Irene Oi-Lin Ng

Cell Death Differ. 2018 Aug; 25(8): 1426–1441. Published online 2018 Feb 14. doi: 10.1038/s41418-018-0059-x

PMCID:: PMC6113239

Abstract Article PDF–5.3M

Select item 581875314.

Cripto stabilizes GRP78 on the cell membrane

Valentina L. Kouznetsova, Hannah Hu, Knut Teigen, Maurizio Zanetti, Igor F. Tsigelny

Protein Sci. 2018 Mar; 27(3): 653–661. Published online 2017 Dec 27. doi: 10.1002/pro.3358

PMCID:: PMC5818753

Abstract Article PDF–3.4M

Select item 556285515.

CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer

E Zoni, L Chen, S Karkampouna, Z Granchi, E I Verhoef, F La Manna, J Kelber, R C M Pelger, M D Henry, E Snaar-Jagalska, G J L H van Leenders, L Beimers, P Kloen, P C Gray, G van der Pluijm, M Kruithof-de Julio

Oncogene. 2017 Aug 17; 36(33): 4739–4749. Published online 2017 Apr 10. doi: 10.1038/onc.2017.87

PMCID:: PMC5562855

Abstract Article PDF–3.7M

Select item 553161116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 542314017.

Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors

Cassy M. Spiller, Ad J.M. Gillis, Guillaume Burnet, Hans Stoop, Peter Koopman, Josephine Bowles, Leendert H.J. Looijenga

Mol Oncol. 2016 Apr; 10(4): 526–537. Published online 2015 Nov 18. doi: 10.1016/j.molonc.2015.11.003

PMCID:: PMC5423140

Abstract Article PDF–2.2M

Select item 539985018.

Cripto-1 acts as a functional marker of cancer stem-like cells and predicts prognosis of the patients in esophageal squamous cell carcinoma

Qiang Liu, Xiang Cui, Xi Yu, Bai-Shi-Jiao Bian, Feng Qian, Xu-gang Hu, Cheng-dong Ji, Lang Yang, Yong Ren, Wei Cui, Xia Zhang, Peng Zhang, Ji Ming Wang, You-hong Cui, Xiu-wu Bian

Mol Cancer. 2017; 16: 81. Published online 2017 Apr 21. doi: 10.1186/s12943-017-0650-7

PMCID:: PMC5399850

Abstract Article PDF–8.3M

Select item 535451419.

Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic

Senem Aykul, Anthony Parenti, Kit Yee Chu, Jake Reske, Monique Floer, Amy Ralston, Erik Martinez-Hackert

J Biol Chem. 2017 Mar 10; 292(10): 4138–4151. Published online 2017 Jan 26. doi: 10.1074/jbc.M116.747501

PMCID:: PMC5354514

Abstract Article PDF–3.1M

Select item 514700220.

A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO

Gun-Hee Lee, Morihisa Fujita, Katsuyoshi Takaoka, Yoshiko Murakami, Yoshitaka Fujihara, Noriyuki Kanzawa, Kei-ichi Murakami, Eriko Kajikawa, Yoko Takada, Kazunobu Saito, Masahito Ikawa, Hiroshi Hamada, Yusuke Maeda, Taroh Kinoshita

J Cell Biol. 2016 Dec 5; 215(5): 705–718. doi: 10.1083/jcb.201605121

PMCID:: PMC5147002

Abstract Article PDF–2.8M

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