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Select item 113461811.

Casein kinase 1α mediates estradiol secretion via CYP19A1 expression in mouse ovarian granulosa cells

Xuan Luo, Di Zhang, Jiaming Zheng, Hui Liu, Longjie Sun, Hongzhou Guo, Lei Wang, Sheng Cui

BMC Biol. 2024; 22: 176. Published online 2024 Aug 26. doi: 10.1186/s12915-024-01957-3

PMCID:: PMC11346181

Abstract Article PDF–2.9M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108798593.

Tripeptidyl peptidase II coordinates the homeostasis of calcium and lipids in the central nervous system and its depletion causes presenile dementia in female mice through calcium/lipid dyshomeostasis-induced autophagic degradation of CYP19A1

Jin Zhao, Chengtong He, Xueyu Fan, Lin Wang, Liao Zhao, Hui Liu, Wujun Shen, Sanwei Jiang, Kaixuan Pei, Jingjing Gao, Yawei Qi, Yang Liu, Junqiang Zhao, Ruiling Zhang, Chengbiao Lu, Jia Tong, Jisen Huai

Theranostics. 2024; 14(4): 1390–1429. Published online 2024 Jan 27. doi: 10.7150/thno.92571

PMCID:: PMC10879859

Abstract Article PDF–17M

Select item 108430464.

Aromatase deficiency in transplanted bone marrow cells improves vertebral trabecular bone quantity, connectivity, and mineralization and decreases cortical porosity in murine bone marrow transplant recipients

Katie Rubitschung, Amber Sherwood, Rasesh Kapadia, Yin Xi, Asghar Hajibeigi, Katya B. Rubinow, Joseph E. Zerwekh, Orhan K. Öz

PLoS One. 2024; 19(2): e0296390. Published online 2024 Feb 5. doi: 10.1371/journal.pone.0296390

PMCID:: PMC10843046

Abstract Article PDF–2.8M

Select item 102877005.

Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice

Xue Jiang, Yu Cheng, Yuzhang Zhu, Caoling Xu, Qiaodan Li, Xuemei Xing, Wenqing Li, Jiaqi Zou, Lan Meng, Muhammad Azhar, Yuzhu Cao, Xianhong Tong, Weibing Qin, Xiaoli Zhu, Jianqiang Bao

Nat Commun. 2023; 14: 3729. Published online 2023 Jun 22. doi: 10.1038/s41467-023-39256-0

PMCID:: PMC10287700

Abstract Article PDF–13M

Select item 98253536.

Decreased Expression of EZH2 in Granulosa Cells Contributes to Endometriosis-Associated Infertility by Targeting IL-1R2

Xiang Lin, Xiaomei Tong, Yinli Zhang, Weijia Gu, Qianmeng Huang, Yi Zhang, Feng Zhuo, Fanxuan Zhao, Xiaoying Jin, Chao Li, Dong Huang, Songying Zhang, Yongdong Dai

Endocrinology. 2023 Feb; 164(2): bqac210. Published online 2022 Dec 16. doi: 10.1210/endocr/bqac210

PMCID:: PMC9825353

Abstract Article

Select item 97686867.

Overexpression of Estrogen Receptor α in Mammary Glands of Aging Mice Is Associated with a Proliferative Risk Signature and Generation of Estrogen Receptor α–Positive Mammary Adenocarcinomas

Priscilla A. Furth, Weisheng Wang, Keunsoo Kang, Brendan L. Rooney, Grace Keegan, Vinona Muralidaran, Justin Wong, Charles Shearer, Xiaojun Zou, Jodi A. Flaws

Am J Pathol. 2023 Jan; 193(1): 103–120. doi: 10.1016/j.ajpath.2022.09.008

PMCID:: PMC9768686

Abstract Article PDF–4.7M

Select item 97686858.

Esr1 but Not CYP19A1 Overexpression in Mammary Epithelial Cells during Reproductive Senescence Induces Pregnancy-Like Proliferative Mammary Disease Responsive to Anti-Hormonals

Priscilla A. Furth, Weisheng Wang, Keunsoo Kang, Brendan L. Rooney, Grace Keegan, Vinona Muralidaran, Xiaojun Zou, Jodi A. Flaws

Am J Pathol. 2023 Jan; 193(1): 84–102. doi: 10.1016/j.ajpath.2022.09.007

PMCID:: PMC9768685

Abstract Article PDF–5.3M

Select item 93380409.

TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway

Moïra Rossitto, Stephanie Déjardin, Chris M. Rands, Stephanie Le Gras, Roberta Migale, Mahmoud-Reza Rafiee, Yasmine Neirijnck, Alain Pruvost, Anvi Laetitia Nguyen, Guillaume Bossis, Florence Cammas, Lionel Le Gallic, Dagmar Wilhelm, Robin Lovell-Badge, Brigitte Boizet-Bonhoure, Serge Nef, Francis Poulat

Nat Commun. 2022; 13: 4412. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32061-1

PMCID:: PMC9338040

Abstract Article PDF–11M

Select item 857083110.

Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain

Philipp Wartenberg, Imre Farkas, Veronika Csillag, William H. Colledge, Erik Hrabovszky, Ulrich Boehm

J Neurosci. 2021 Nov 3; 41(44): 9177–9191. doi: 10.1523/JNEUROSCI.0885-21.2021

PMCID:: PMC8570831

Abstract Article PDF–9.6M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 772654012.

Astrocyte-Derived Estrogen Regulates Reactive Astrogliosis and is Neuroprotective following Ischemic Brain Injury

Jing Wang, Gangadhara R. Sareddy, Yujiao Lu, Uday P. Pratap, Fulei Tang, Karah M. Greene, Pornjittra L. Meyre, Rajeshwar R. Tekmal, Ratna K. Vadlamudi, Darrell W. Brann

J Neurosci. 2020 Dec 9; 40(50): 9751–9771. doi: 10.1523/JNEUROSCI.0888-20.2020

PMCID:: PMC7726540

Abstract Article PDF–10M

Select item 760987613.

Aberrant and constitutive expression of FOXL2 impairs ovarian development and functions in mice

Barbara Nicol, Karina Rodriguez, Humphrey H-C Yao

Biol Reprod. 2020 Nov; 103(5): 966–977. Published online 2020 Aug 25. doi: 10.1093/biolre/ioaa146

PMCID:: PMC7609876

Abstract Article PDF–2.7M

Select item 759156614.

Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice

Juan Antonio Aguilar-Pimentel, Yi-Li Cho, Raffaele Gerlini, Julia Calzada-Wack, Maria Wimmer, Philipp Mayer-Kuckuk, Thure Adler, Carsten B. Schmidt-Weber, Dirk H. Busch, Helmut Fuchs, Valérie Gailus-Durner, Markus Ollert, Martin Hrabě de Angelis, Claes Ohlsson, Matti Poutanen, Raffaele Teperino, Leena Strauss

Sci Rep. 2020; 10: 18334. Published online 2020 Oct 27. doi: 10.1038/s41598-020-75059-9

PMCID:: PMC7591566

Abstract Article PDF–2.7M

Select item 753492015.

Neuron-Derived Estrogen Is Critical for Astrocyte Activation and Neuroprotection of the Ischemic Brain

Yujiao Lu, Gangadhara R. Sareddy, Jing Wang, Quanguang Zhang, Fu-Lei Tang, Uday P. Pratap, Rajeshwar R. Tekmal, Ratna K. Vadlamudi, Darrell W. Brann

J Neurosci. 2020 Sep 16; 40(38): 7355–7374. doi: 10.1523/JNEUROSCI.0115-20.2020

PMCID:: PMC7534920

Abstract Article PDF–9.6M

Select item 748527416.

Brain Aromatase and the Regulation of Sexual Activity in Male Mice

David C Brooks, John S Coon V, Cihangir M Ercan, Xia Xu, Hongxin Dong, Jon E Levine, Serdar E Bulun, Hong Zhao

Endocrinology. 2020 Oct; 161(10): bqaa137. Published online 2020 Sep 10. doi: 10.1210/endocr/bqaa137

PMCID:: PMC7485274

Abstract Article

Select item 743800617.

miR-206 enforces a slow muscle phenotype

Kristen K. Bjorkman, Martin G. Guess, Brooke C. Harrison, Michael M. Polmear, Angela K. Peter, Leslie A. Leinwand

J Cell Sci. 2020 Aug 1; 133(15): jcs243162. Published online 2020 Aug 11. doi: 10.1242/jcs.243162

PMCID:: PMC7438006

Abstract Article

Select item 741787918.

Peri- and Postpubertal Estrogen Exposures of Female Mice Optimize Uterine Responses Later in Life

Sylvia C Hewitt, Marleny Carmona, K Grace Foley, Lauren J Donoghue, Sydney L Lierz, Wipawee Winuthayanon, Kenneth S Korach

Endocrinology. 2020 Aug; 161(8): bqaa081. Published online 2020 Jul 5. doi: 10.1210/endocr/bqaa081

PMCID:: PMC7417879

Abstract Article

Select item 738796619.

Changes in nucleus accumbens gene expression accompany sex-specific suppression of spontaneous physical activity in aromatase knockout mice

Dusti A. Shay, Rebecca J. Welly, Scott A. Givan, Nathan Bivens, Jill Kanaley, Brittney L. Marshall, Dennis B. Lubahn, Cheryl S. Rosenfeld, Victoria J. Vieira-Potter

Horm Behav. Author manuscript; available in PMC 2020 Jul 29.

Published in final edited form as: Horm Behav. 2020 May; 121: 104719. Published online 2020 Feb 29. doi: 10.1016/j.yhbeh.2020.104719

PMCID:: PMC7387966

Abstract Article PDF–1.1M

Select item 697773920.

Aromatase deficiency in hematopoietic cells improves glucose tolerance in male mice through skeletal muscle-specific effects

Katya B. Rubinow, Laura J. den Hartigh, Leela Goodspeed, Shari Wang, Orhan K. Oz

PLoS One. 2020; 15(1): e0227830. Published online 2020 Jan 23. doi: 10.1371/journal.pone.0227830

PMCID:: PMC6977739

Abstract Article PDF–2.1M

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