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Items: 1 to 20 of 29

1.
Cancer cell survival depends on collagen uptake into tumor-associated stroma
Kuo-Sheng Hsu, James M. Dunleavey, Christopher Szot, Liping Yang, Mary Beth Hilton, Karen Morris, Steven Seaman, Yang Feng, Emily M. Lutz, Robert Koogle, Francesco Tomassoni-Ardori, Saurabh Saha, Xiaoyan M. Zhang, Enrique Zudaire, Pradip Bajgain, Joshua Rose, Zhongyu Zhu, Dimiter S. Dimitrov, Frank Cuttitta, Nancy J. Emenaker, Lino Tessarollo, Brad St. Croix
Nat Commun. 2022; 13: 7078. Published online 2022 Nov 18. doi: 10.1038/s41467-022-34643-5
PMCID:
PMC9674701
AbstractArticlePDF–7.1M
2.
Imaging of anthrax intoxication in mice reveals shared and individual functions of surface receptors CMG-2 and TEM-8 in cellular toxin entry
Carly Merritt, Elizabeth M. Chun, Rasem J. Fattah, Lakmali M. Silva, Quinn Q. Ma, Mahtab Moayeri, Dennis Paliga, Sebastian Neumann, Rolf Heumann, Stephen H. Leppla, Thomas H. Bugge
J Biol Chem. 2022 Jan; 298(1): 101467. Published online 2021 Dec 4. doi: 10.1016/j.jbc.2021.101467
PMCID:
PMC8716333
AbstractArticlePDF–6.5M
3.
Targeted silencing of TEM8 suppresses non-small cell lung cancer tumor growth via the ERK/Bcl-2 signaling pathway
Quan Gong, Jing Deng, Lijuan Zhang, Chunyan Zhou, Chaojiang Fu, Xicai Wang, Li Zhuang
Mol Med Rep. 2021 Aug; 24(2): 595. Published online 2021 Jun 22. doi: 10.3892/mmr.2021.12234
PMCID:
PMC8240451
AbstractArticlePDF–771K
4.
Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis
Qing Jiang, Xin Qin, Carolina Andrea Yoshida, Hisato Komori, Kei Yamana, Shinsuke Ohba, Hironori Hojo, Brad St. Croix, Viviane K. S. Kawata-Matsuura, Toshihisa Komori
Int J Mol Sci. 2020 Apr; 21(7): 2425. Published online 2020 Mar 31. doi: 10.3390/ijms21072425
PMCID:
PMC7178079
AbstractArticlePDF–8.1M
5.
Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST
Yoko Nakano, Susan Wiechert, Botond Bánfi
Cell Rep. Author manuscript; available in PMC 2019 Jun 9.
Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 860–871.e8. doi: 10.1016/j.celrep.2019.03.072
PMCID:
PMC6556397
AbstractArticlePDF–2.3M
6.
Tumor stroma–targeted antibody-drug conjugate triggers localized anticancer drug release
Christopher Szot, Saurabh Saha, Xiaoyan M. Zhang, Zhongyu Zhu, Mary Beth Hilton, Karen Morris, Steven Seaman, James M. Dunleavey, Kuo-Sheng Hsu, Guo-Jun Yu, Holly Morris, Deborah A. Swing, Diana C. Haines, Yanping Wang, Jennifer Hwang, Yang Feng, Dean Welsch, Gary DeCrescenzo, Amit Chaudhary, Enrique Zudaire, Dimiter S. Dimitrov, Brad St. Croix
J Clin Invest. 2018 Jul 2; 128(7): 2927–2943. Published online 2018 Jun 4. doi: 10.1172/JCI120481
PMCID:
PMC6025988
AbstractArticlePDF–18M
7.
Cell autonomous ANTXR1-mediated regulation of extracellular matrix components in primary fibroblasts
Kai Hu, Bjorn R. Olsen, Tatiana Y. Besschetnova
Matrix Biol. Author manuscript; available in PMC 2018 Oct 1.
Published in final edited form as: Matrix Biol. 2017 Oct; 62: 105–114. Published online 2016 Dec 20. doi: 10.1016/j.matbio.2016.12.002
PMCID:
PMC5478475
AbstractArticlePDF–1024K
8.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
9.
Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 or TEM8 Receptors for Cellular Uptake and Tumor Targeting
Kuang-Hua Chen, Shihui Liu, Clinton E. Leysath, Sharmina Miller-Randolph, Yi Zhang, Rasem Fattah, Thomas H. Bugge, Stephen H. Leppla
J Biol Chem. 2016 Oct 14; 291(42): 22021–22029. Published online 2016 Aug 23. doi: 10.1074/jbc.M116.753301
PMCID:
PMC5063985
AbstractArticlePDF–338K
10.
Solid tumor therapy by selectively targeting stromal endothelial cells
Shihui Liu, Jie Liu, Qian Ma, Liu Cao, Rasem J. Fattah, Zuxi Yu, Thomas H. Bugge, Toren Finkel, Stephen H. Leppla
Proc Natl Acad Sci U S A. 2016 Jul 12; 113(28): E4079–E4087. Published online 2016 Jun 29. doi: 10.1073/pnas.1600982113
PMCID:
PMC4948345
AbstractArticlePDF–1.1M
11.
Anthrax Toxin Receptor 1 Is Essential for Arteriogenesis in a Mouse Model of Hindlimb Ischemia
N. J. Andersen, E. A. Boguslawski, A. S. Naidu, C. Szot, J. L. Bromberg-White, K. Kits, C. Y. Kuk, L. E. Holton, B. St. Croix, C. M. Chambers, N. S. Duesbery
PLoS One. 2016; 11(1): e0146586. Published online 2016 Jan 19. doi: 10.1371/journal.pone.0146586
PMCID:
PMC4718698
AbstractArticlePDF–1.7M
12.
Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis
Tatiana Y. Besschetnova, Takaharu Ichimura, Negin Katebi, Brad St. Croix, Joseph V. Bonventre, Bjorn R. Olsen
Matrix Biol. Author manuscript; available in PMC 2016 Mar 1.
Published in final edited form as: Matrix Biol. 2015 Mar; 42: 56–73. Published online 2015 Jan 5. doi: 10.1016/j.matbio.2014.12.002
PMCID:
PMC4409530
AbstractArticlePDF–3.4M
13.
Targeted Silencing of Anthrax Toxin Receptors Protects against Anthrax Toxins
Maria T. Arévalo, Ashley Navarro, Chenoa D. Arico, Junwei Li, Omar Alkhatib, Shan Chen, Diana Diaz-Arévalo, Mingtao Zeng
J Biol Chem. 2014 May 30; 289(22): 15730–15738. Published online 2014 Apr 17. doi: 10.1074/jbc.M113.538587
PMCID:
PMC4140927
AbstractArticlePDF–1.1M
14.
The Receptors that Mediate the Direct Lethality of Anthrax Toxin
Shihui Liu, Yi Zhang, Benjamin Hoover, Stephen H. Leppla
Toxins (Basel) 2013 Jan; 5(1): 1–8. Published online 2012 Dec 27. doi: 10.3390/toxins5010001
PMCID:
PMC3564063
AbstractArticlePDF–329K
15.
TEM8/ANTXR1 Blockade Inhibits Pathological Angiogenesis and Potentiates Tumoricidal Responses against Multiple Cancer Types
Amit Chaudhary, Mary Beth Hilton, Steven Seaman, Diana C. Haines, Susan Stevenson, Peter K. Lemotte, William R. Tschantz, Xiaoyan M. Zhang, Saurabh Saha, Tony Fleming, Brad St. Croix
Cancer Cell. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Cancer Cell. 2012 Feb 14; 21(2): 212–226. doi: 10.1016/j.ccr.2012.01.004
PMCID:
PMC3289547
AbstractArticlePDF–6.3M
16.
Anthrax Edema Toxin Impairs Clearance in Mice
Inka Sastalla, Shixing Tang, Devorah Crown, Shihui Liu, Michael A. Eckhaus, Indira K. Hewlett, Stephen H. Leppla, Mahtab Moayeri
Infect Immun. 2012 Feb; 80(2): 529–538. doi: 10.1128/IAI.05947-11
PMCID:
PMC3264307
AbstractArticlePDF–2.1M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood–brain barrier
Mike Cullen, Mohammed K. Elzarrad, Steven Seaman, Enrique Zudaire, Janine Stevens, Mi Young Yang, Xiujie Li, Amit Chaudhary, Lihong Xu, Mary Beth Hilton, Daniel Logsdon, Emily Hsiao, Erica V. Stein, Frank Cuttitta, Diana C. Haines, Kunio Nagashima, Lino Tessarollo, Brad St. Croix
Proc Natl Acad Sci U S A. 2011 Apr 5; 108(14): 5759–5764. Published online 2011 Mar 18. doi: 10.1073/pnas.1017192108
PMCID:
PMC3078373
AbstractArticlePDF–1.1M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
The Cell Surface Structure of Tumor Endothelial Marker 8 (TEM8) is Regulated by the Actin Cytoskeleton
Mi Young Yang, Amit Chaudhary, Steven Seaman, Jill Dunty, Janine Stevens, Mohammed K. Elzarrad, Arthur E. Frankel, Brad St. Croix
Biochim Biophys Acta. Author manuscript; available in PMC 2012 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2011 Jan; 1813(1): 39–49. Published online 2010 Dec 1. doi: 10.1016/j.bbamcr.2010.11.013
PMCID:
PMC3014418
AbstractArticlePDF–3.5M

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