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Items: 1 to 20 of 127

1.
Deletion of Fbxw7 in oocytes causes follicle loss and premature ovarian insufficiency in mice
Huihui Zhao, Hanbin Zhang, Yuxia Zhou, Ling Shuai, Zhenguo Chen, Liping Wang
J Cell Mol Med. 2024 Jun; 28(12): e18487. Published online 2024 Jun 21. doi: 10.1111/jcmm.18487
PMCID:
PMC11190952
AbstractArticlePDF–32M
2.
Angiogenesis is uncoupled from osteogenesis during calvarial bone regeneration
M. Gabriele Bixel, Kishor K. Sivaraj, Melanie Timmen, Vishal Mohanakrishnan, Anusha Aravamudhan, Susanne Adams, Bong-Ihn Koh, Hyun-Woo Jeong, Kai Kruse, Richard Stange, Ralf H. Adams
Nat Commun. 2024; 15: 4575. Published online 2024 Jun 4. doi: 10.1038/s41467-024-48579-5
PMCID:
PMC11150404
AbstractArticlePDF–9.1M
3.
Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo
Zhaohua Cai, Shaojin You, Zhixue Liu, Ping Song, Fujie Zhao, Junqing An, Ye Ding, Ben He, Ming-Hui Zou
Cell Death Dis. 2024 Mar; 15(3): 212. Published online 2024 Mar 14. doi: 10.1038/s41419-024-06597-7
PMCID:
PMC10940678
AbstractArticlePDF–8.0M
4.
FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer
Zhiyuan Zhou, Bin Zhang, Yue Deng, Suke Deng, Jie Li, Wenwen Wei, Yijun Wang, Jiacheng Wang, Zishan Feng, Mengjie Che, Xiao Yang, Jingshu Meng, Yan Li, Yan Hu, Yajie Sun, Lu Wen, Fang Huang, Yuhan Sheng, Chao Wan, Kunyu Yang
J Exp Clin Cancer Res. 2024; 43: 34. Published online 2024 Jan 29. doi: 10.1186/s13046-024-02959-3
PMCID:
PMC10823633
AbstractArticlePDF–10M
5.
Hepatocyte FBXW7-dependent activity of nutrient-sensing nuclear receptors controls systemic energy homeostasis and NASH progression in male mice
Hui Xia, Catherine R. Dufour, Younes Medkour, Charlotte Scholtes, Yonghong Chen, Christina Guluzian, Wafa B’chir, Vincent Giguère
Nat Commun. 2023; 14: 6982. Published online 2023 Nov 1. doi: 10.1038/s41467-023-42785-3
PMCID:
PMC10620240
AbstractArticlePDF–3.5M
6.
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis
Matthew Brown, Alicia Leon, Katarzyna Kedzierska, Charlotte Moore, Hayley L Belnoue‐Davis, Susanne Flach, John P Lydon, Francesco J DeMayo, Annabelle Lewis, Tjalling Bosse, Ian Tomlinson, David N Church
EMBO Mol Med. 2023 Oct; 15(10): e17094. Published online 2023 Aug 17. doi: 10.15252/emmm.202217094
PMCID:
PMC10565641
AbstractArticlePDF–3.5M
7.
High‐fat diet aggravates the severity of the in vitro posttraumatic osteoarthritis model through macrophagic FBW7
Lijun Duan, Yuan Ma, Chen‐Guang Feng, Xing Yu
Immun Inflamm Dis. 2023 Sep; 11(9): e988. Published online 2023 Sep 26. doi: 10.1002/iid3.988
PMCID:
PMC10521371
AbstractArticlePDF–2.3M
8.
FBXW7 Enhances Cisplatin-Induced Apoptosis in Oral Cancer Cell Lines
Qi Yang, Yang Sun, Bo Qiu, Huanhuan Zhao
Int Dent J. 2023 Oct; 73(5): 620–627. Published online 2022 Dec 5. doi: 10.1016/j.identj.2022.11.008
PMCID:
PMC10509406
AbstractArticlePDF–1.4M
9.
巨噬细胞中FBXW7基因缺失对小鼠黑色素瘤肺转移的影响
Wei ZHANG, Lihua LAI, Qingqing WANG
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2017 Apr 25; 46(2): 111–117. Chinese. doi: 10.3785/j.issn.1008-9292.2017.04.01
PMCID:
PMC10396932
AbstractArticlePDF–4.7M
10.
FBXW7 inactivation induces cellular senescence via accumulation of p53
Longyuan Gong, Danrui Cui, Dian Liu, Xiao Shen, Hui Pan, Xiufang Xiong, Yongchao Zhao
Cell Death Dis. 2022 Sep; 13(9): 788. Published online 2022 Sep 14. doi: 10.1038/s41419-022-05229-2
PMCID:
PMC9475035
AbstractArticlePDF–9.6M
11.
E3 Ligase FBXW7 Facilitates Mycobacterium Immune Evasion by Modulating TNF-α Expression
Jingrui Song, Jin Chao, Xiaohong Hu, Xin Wen, Cairong Ding, Dan Li, Ding Zhang, Shanshan Han, Xiang Yu, Bo Yan, Zhu Jin, Yinhong Song, Jacqueline Gonzales, Laura E. Via, Lu Zhang, Decheng Wang
Front Cell Infect Microbiol. 2022; 12: 851197. Published online 2022 May 16. doi: 10.3389/fcimb.2022.851197
PMCID:
PMC9149249
AbstractArticlePDF–9.6M
12.
Insulin action and resistance are dependent on a GSK3β-FBXW7-ERRα transcriptional axis
Hui Xia, Charlotte Scholtes, Catherine R. Dufour, Carlo Ouellet, Majid Ghahremani, Vincent Giguère
Nat Commun. 2022; 13: 2105. Published online 2022 Apr 19. doi: 10.1038/s41467-022-29722-6
PMCID:
PMC9019090
AbstractArticlePDF–2.8M
13.
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
H Nayanga Thirimanne, Feinan Wu, Derek H Janssens, Jherek Swanger, Ahmed Diab, Heather M Feldman, Robert A Amezquita, Raphael Gottardo, Patrick J Paddison, Steven Henikoff, Bruce E Clurman
eLife. 2022; 11: e74338. Published online 2022 Feb 28. doi: 10.7554/eLife.74338
PMCID:
PMC8926403
AbstractArticlePDF–7.9M
14.
Inactivation of Fbxw7 impairs dsRNA sensing and confers resistance to PD-1 blockade
Cécile Gstalder, David Liu, Diana Miao, Bart Lutterbach, Alexander L. Devine, Chenyu Lin, Megha Shettigar, Priya Pancholi, Elizabeth I. Buchbinder, Scott L. Carter, Michael P. Manos, Vanesa Rojas-Rudilla, Ryan Brennick, Evisa Gjini, Pei-Hsuan Chen, Ana Lako, Scott Rodig, Charles H. Yoon, Gordon J. Freeman, David A. Barbie, F. Stephen Hodi, Wayne Miles, Eliezer M. Van Allen, Rizwan Haq
Cancer Discov. Author manuscript; available in PMC 2022 Jan 31.
Published in final edited form as: Cancer Discov. 2020 Sep; 10(9): 1296–1311. Published online 2020 May 5. doi: 10.1158/2159-8290.CD-19-1416
PMCID:
PMC8802534
AbstractArticlePDF–1.9M
15.
Myeloid Fbxw7 Prevents Pulmonary Fibrosis by Suppressing TGF-β Production
Jia He, Yue Du, Gaopeng Li, Peng Xiao, Xingzheng Sun, Wenjun Song, Lihua Lai, Meng Xia, Jianhua Zhang, Qingqing Wang
Front Immunol. 2021; 12: 760138. Published online 2022 Jan 5. doi: 10.3389/fimmu.2021.760138
PMCID:
PMC8767095
AbstractArticlePDF–14M
16.
USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma
E Josue Ruiz, Adan Pinto-Fernandez, Andrew P Turnbull, Linxiang Lan, Thomas M Charlton, Hannah C Scott, Andreas Damianou, George Vere, Eva M Riising, Clive Da Costa, Wojciech W Krajewski, David Guerin, Jeffrey D Kearns, Stephanos Ioannidis, Marie Katz, Crystal McKinnon, Jonathan O'Connell, Natalia Moncaut, Ian Rosewell, Emma Nye, Neil Jones, Claire Heride, Malte Gersch, Min Wu, Christopher J Dinsmore, Tim R Hammonds, Sunkyu Kim, David Komander, Sylvie Urbe, Michael J Clague, Benedikt M Kessler, Axel Behrens
eLife. 2021; 10: e71596. Published online 2021 Oct 12. doi: 10.7554/eLife.71596
PMCID:
PMC8553340
AbstractArticlePDF–4.1M
17.
Critical roles of the E3 ubiquitin ligase FBW7 in B‐cell response and the pathogenesis of experimental autoimmune arthritis
Chunlei Feng, Lingyun Li, Lei Zhou, Dali Li, Mingyao Liu, Shuhua Han, Biao Zheng
Immunology. 2021 Nov; 164(3): 617–636. Published online 2021 Aug 16. doi: 10.1111/imm.13398
PMCID:
PMC8517593
AbstractArticlePDF–1.6M
18.
FBW7 couples structural integrity with functional output of primary cilia
Eleni Petsouki, Vasileios Gerakopoulos, Nicholas Szeto, Wenhan Chang, Mary Beth Humphrey, Leonidas Tsiokas
Commun Biol. 2021; 4: 1066. Published online 2021 Sep 13. doi: 10.1038/s42003-021-02504-4
PMCID:
PMC8438042
AbstractArticlePDF–3.0M
19.
Single allele loss-of-function mutations select and sculpt conditional cooperative networks in breast cancer
Nathan F. Schachter, Jessica R. Adams, Patryk Skowron, Katelyn. J. Kozma, Christian A. Lee, Nandini Raghuram, Joanna Yang, Amanda J. Loch, Wei Wang, Aaron Kucharczuk, Katherine L. Wright, Rita M. Quintana, Yeji An, Daniel Dotzko, Jennifer L. Gorman, Daria Wojtal, Juhi S. Shah, Paul Leon-Gomez, Giovanna Pellecchia, Adam J. Dupuy, Charles M. Perou, Ittai Ben-Porath, Rotem Karni, Eldad Zacksenhaus, Jim R. Woodgett, Susan J. Done, Livia Garzia, A. Sorana Morrissy, Jüri Reimand, Michael D. Taylor, Sean E. Egan
Nat Commun. 2021; 12: 5238. Published online 2021 Sep 2. doi: 10.1038/s41467-021-25467-w
PMCID:
PMC8413298
AbstractArticlePDF–4.4M
20.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M

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