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Items: 1 to 20 of 77

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups
María-Jesús Lobón-Iglesias, Mamy Andrianteranagna, Zhi-Yan Han, Céline Chauvin, Julien Masliah-Planchon, Valeria Manriquez, Arnault Tauziede-Espariat, Sandrina Turczynski, Rachida Bouarich-Bourimi, Magali Frah, Christelle Dufour, Thomas Blauwblomme, Liesbeth Cardoen, Gaelle Pierron, Laetitia Maillot, Delphine Guillemot, Stéphanie Reynaud, Christine Bourneix, Célio Pouponnot, Didier Surdez, Mylene Bohec, Sylvain Baulande, Olivier Delattre, Eliane Piaggio, Olivier Ayrault, Joshua J. Waterfall, Nicolas Servant, Kevin Beccaria, Volodia Dangouloff-Ros, Franck Bourdeaut
Nat Commun. 2023; 14: 6669. Published online 2023 Oct 20. doi: 10.1038/s41467-023-42371-7
PMCID:
PMC10589300
AbstractArticlePDF–16M
3.
A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice
Aliska K. Brugmans, Carolin Walter, Natalia Moreno, Carolin Göbel, Dörthe Holdhof, Flavia W. de Faria, Marc Hotfilder, Daniela Jeising, Michael C. Frühwald, Boris V. Skryabin, Timofey S. Rozhdestvensky, Lydia Wachsmuth, Cornelius Faber, Martin Dugas, Julian Varghese, Ulrich Schüller, Thomas K. Albert, Kornelius Kerl
Cell Mol Neurobiol. 2023; 43(7): 3511–3526. Published online 2023 May 23. doi: 10.1007/s10571-023-01361-5
PMCID:
PMC10477118
AbstractArticlePDF–5.0M
4.
SMARCB1 regulates the hypoxic stress response in sickle cell trait
Melinda Soeung, Luigi Perelli, Ziheng Chen, Eleonora Dondossola, I-Lin Ho, Federica Carbone, Li Zhang, Hania Khan, Courtney N. Le, Cihui Zhu, Michael D. Peoples, Ningping Feng, Shan Jiang, Niki Millward Zacharias, Rosalba Minelli, Daniel D. Shapiro, Angela K. Deem, Sisi Gao, Emily H. Cheng, Donatella Lucchetti, Cheryl L. Walker, Alessandro Carugo, Virginia Giuliani, Timothy P. Heffernan, Andrea Viale, Nizar M. Tannir, Giulio F. Draetta, Pavlos Msaouel, Giannicola Genovese
Proc Natl Acad Sci U S A. 2023 May 23; 120(21): e2209639120. Published online 2023 May 15. doi: 10.1073/pnas.2209639120
PMCID:
PMC10214195
AbstractArticlePDF–4.4M
5.
The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis
Pengfei Guo, Nam Hoang, Joseph Sanchez, Elaine H. Zhang, Keshari Rajawasam, Kristiana Trinidad, Hong Sun, Hui Zhang
Nat Commun. 2022; 13: 6696. Published online 2022 Nov 5. doi: 10.1038/s41467-022-34348-9
PMCID:
PMC9637158
AbstractArticlePDF–3.3M
6.
cBAF complex components and MYC cooperate early in CD8+ T cell fate
Ao Guo, Hongling Huang, Zhexin Zhu, Mark J. Chen, Hao Shi, Sujing Yuan, Piyush Sharma, Jon P. Connelly, Swantje Liedmann, Yogesh Dhungana, Zhenrui Li, Dalia Haydar, Mao Yang, Helen Beere, Jason T Yustein, Christopher DeRenzo, Shondra M. Pruett-Miller, Jeremy Chase Crawford, Giedre Krenciute, Charles W.M. Roberts, Hongbo Chi, Douglas R. Green
Nature. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Nature. 2022 Jul; 607(7917): 135–141. Published online 2022 Jun 22. doi: 10.1038/s41586-022-04849-0
PMCID:
PMC9623036
AbstractArticlePDF–6.1M
7.
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome
Sasha L. Fulton, Wendy Wenderski, Ashley E. Lepack, Andrew L. Eagle, Tomas Fanutza, Ryan M. Bastle, Aarthi Ramakrishnan, Emma C. Hays, Arianna Neal, Jaroslav Bendl, Lorna A. Farrelly, Amni Al-Kachak, Yang Lyu, Bulent Cetin, Jennifer C. Chan, Tina N. Tran, Rachael L. Neve, Randall J. Roper, Kristen J. Brennand, Panos Roussos, John C. Schimenti, Allyson K. Friedman, Li Shen, Robert D. Blitzer, Alfred J. Robison, Gerald R. Crabtree, Ian Maze
Nat Commun. 2022; 13: 6384. Published online 2022 Oct 26. doi: 10.1038/s41467-022-34200-0
PMCID:
PMC9606253
AbstractArticlePDF–4.0M
8.
Notch signaling promotes mature T-cell lymphomagenesis
Xin Gao, Chenguang Wang, Suhaib Abdelrahman, Nermin Kady, Carlos Murga-Zamalloa, Peter Gann, Maria Sverdlov, Ashley Wolfe, Avery Polk, Noah Brown, Nathanael G. Bailey, Kedar Inamdar, Sandro Casavilca, Jaime Montes, Carlos Barrionuevo, Luis Taxa, John Reneau, Christian W. Siebel, Ivan Maillard, Ryan A. Wilcox
Cancer Res. Author manuscript; available in PMC 2023 Oct 17.
Published in final edited form as: Cancer Res. 2022 Oct 17; 82(20): 3763–3773. doi: 10.1158/0008-5472.CAN-22-1215
PMCID:
PMC9588752
AbstractArticlePDF–1.1M
9.
Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors
Monika Graf, Marta Interlandi, Natalia Moreno, Dörthe Holdhof, Carolin Göbel, Viktoria Melcher, Julius Mertins, Thomas K. Albert, Dennis Kastrati, Amelie Alfert, Till Holsten, Flavia de Faria, Michael Meisterernst, Claudia Rossig, Monika Warmuth-Metz, Johannes Nowak, Gerd Meyer zu Hörste, Chloe Mayère, Serge Nef, Pascal Johann, Michael C. Frühwald, Martin Dugas, Ulrich Schüller, Kornelius Kerl
Nat Commun. 2022; 13: 1544. Published online 2022 Mar 22. doi: 10.1038/s41467-022-29152-4
PMCID:
PMC8941154
AbstractArticlePDF–7.0M
10.
SWI/SNF chromatin remodeling complex is required for initiation of sex-dependent differentiation in mouse germline
Toshiaki Ito, Atsuki Osada, Masami Ohta, Kana Yokota, Akira Nishiyama, Yuichi Niikura, Tomohiko Tamura, Yoichi Sekita, Tohru Kimura
Sci Rep. 2021; 11: 24074. Published online 2021 Dec 15. doi: 10.1038/s41598-021-03538-8
PMCID:
PMC8674328
AbstractArticlePDF–5.3M
11.
A Role for SMARCB1 in Synovial Sarcomagenesis Reveals That SS18–SSX Induces Canonical BAF Destruction
Jinxiu Li, Timothy S. Mulvihill, Li Li, Jared J. Barrott, Mary L. Nelson, Lena Wagner, Ian C. Lock, Amir Pozner, Sydney Lynn Lambert, Benjamin B. Ozenberger, Michael B. Ward, Allie H. Grossmann, Ting Liu, Ana Banito, Bradley R. Cairns, Kevin B. Jones
Cancer Discov. 2021 Oct 1; 11(10): 2620–2637. Published online 2021 Jun 2. doi: 10.1158/2159-8290.CD-20-1219
PMCID:
PMC8567602
AbstractArticlePDF–15M
12.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
13.
SWI/SNF complex mutations promote thyroid tumor progression and insensitivity to redifferentiation therapies.
Mahesh Saqcena, Luis Javier Leandro-Garcia, Jesper L. V. Maag, Vatche Tchekmedyian, Gnana P. Krishnamoorthy, Prasanna P. Tamarapu, Vera Tiedje, Vincent Reuter, Jeffrey A. Knauf, Elisa de Stanchina, Bin Xu, Xiao-Hui Liao, Samuel Refetoff, Ronald Ghossein, Ping Chi, Alan L. Ho, Richard P. Koche, James A. Fagin
Cancer Discov. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: Cancer Discov. 2021 May; 11(5): 1158–1175. Published online 2020 Dec 14. doi: 10.1158/2159-8290.CD-20-0735
PMCID:
PMC8102308
AbstractArticlePDF–2.9M
14.
Interplay of BAF and MLL4 promotes cell type-specific enhancer activation
Young-Kwon Park, Ji-Eun Lee, Zhijiang Yan, Kaitlin McKernan, Tommy O’Haren, Weidong Wang, Weiqun Peng, Kai Ge
Nat Commun. 2021; 12: 1630. Published online 2021 Mar 12. doi: 10.1038/s41467-021-21893-y
PMCID:
PMC7955098
AbstractArticlePDF–5.5M
15.
p53 is a master regulator of proteostasis in SMARCB1-deficient malignant rhabdoid tumors
Alessandro Carugo, Rosalba Minelli, Luigi Sapio, Melinda Soeung, Federica Carbone, Frederick S. Robinson, James Tepper, Chen Ziheng, Sara Lovisa, Maria Svelto, Samirkumar Amin, Sanjana Srinivasan, Edoardo Del Poggetto, Sara Loponte, Francesca Puca, Prasenjit Dey, Gabriel G. Malouf, Xiaoping Su, Liren Li, Dolores Lopez-Terrada, Dinesh Rakheja, Alexander J. Lazar, George J. Netto, Priya Rao, Alessandro Sgambato, Anirban Maitra, Durga N. Tripathi, Cheryl L. Walker, Jose A. Karam, Timothy P. Heffernan, Andrea Viale, Charles W. M. Roberts, Pavlos Msaouel, Nizar M. Tannir, Giulio F. Draetta, Giannicola Genovese
Cancer Cell. Author manuscript; available in PMC 2021 Feb 11.
Published in final edited form as: Cancer Cell. 2019 Feb 11; 35(2): 204–220.e9. doi: 10.1016/j.ccell.2019.01.006
PMCID:
PMC7876656
AbstractArticlePDF–4.5M
16.
Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer
Giannicola Genovese, Alessandro Carugo, James Tepper, Frederick Scott Robinson, Liren Li, Maria Svelto, Luigi Nezi, Denise Corti, Rosalba Minelli, Piergiorgio Pettazzoni, Tony Gutschner, Chia-Chin Wu, Sahil Seth, Kadir Caner Akdemir, Elisabetta Leo, Samirkumar Amin, Marco Dal Molin, Haoqiang Ying, Lawrence N. Kwong, Simona Colla, Koichi Takahashi, Papia Ghosh, Virginia Giuliani, Florian Muller, Prasenjit Dey, Shan Jiang, Jill Garvey, Chang-Gong Liu, Jianhua Zhang, Timothy P. Heffernan, Carlo Toniatti, Jason B. Fleming, Michael G. Goggins, Laura D. Wood, Alessandro Sgambato, Abbas Agaimy, Anirban Maitra, Charles W. M. Roberts, Huamin Wang, Andrea Viale, Ronald A. DePinho, Giulio F. Draetta, Lynda Chin
Nature. Author manuscript; available in PMC 2020 Nov 3.
Published in final edited form as: Nature. 2017 Feb 16; 542(7641): 362–366. Published online 2017 Feb 8. doi: 10.1038/nature21064
PMCID:
PMC7609022
AbstractArticlePDF–6.9M
17.
The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation
Jeannine M. Basta, Ajeet P. Singh, Lynn Robbins, Lisa Stout, Michelle Pherson, Michael Rauchman
Dev Biol. Author manuscript; available in PMC 2020 Sep 27.
Published in final edited form as: Dev Biol. 2020 Aug 15; 464(2): 176–187. Published online 2020 Jun 3. doi: 10.1016/j.ydbio.2020.05.008
PMCID:
PMC7520014
AbstractArticlePDF–2.6M
18.
A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function
Chin-San Loo, Jovylyn Gatchalian, Yuqiong Liang, Mathias Leblanc, Mingjun Xie, Josephine Ho, Bhargav Venkatraghavan, Diana C. Hargreaves, Ye Zheng
Immunity. 2020 Jul 14; 53(1): 143–157.e8. Published online 2020 Jul 7. doi: 10.1016/j.immuni.2020.06.011
PMCID:
PMC7341821
AbstractArticlePDF–4.7M
19.
Mutations in SMARCB1 and in other Coffin–Siris syndrome genes lead to various brain midline defects
Alina Filatova, Linda K. Rey, Marion B. Lechler, Jörg Schaper, Maja Hempel, Renata Posmyk, Krzysztof Szczaluba, Gijs W. E. Santen, Dagmar Wieczorek, Ulrike A. Nuber
Nat Commun. 2019; 10: 2966. Published online 2019 Jul 4. doi: 10.1038/s41467-019-10849-y
PMCID:
PMC6609698
AbstractArticlePDF–4.0M
20.
Loss of Smarc Proteins Impairs Cerebellar Development
Natalia Moreno, Christin Schmidt, Julia Ahlfeld, Julia Pöschl, Stefanie Dittmar, Stefan M. Pfister, Marcel Kool, Kornelius Kerl, Ulrich Schüller
J Neurosci. 2014 Oct 1; 34(40): 13486–13491. doi: 10.1523/JNEUROSCI.2560-14.2014
PMCID:
PMC6608313
AbstractArticlePDF–1.9M

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