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Select item 112511671.

MCM8 interacts with DDX5 to promote R-loop resolution

Canxin Wen, Lili Cao, Shuhan Wang, Weiwei Xu, Yongze Yu, Simin Zhao, Fan Yang, Zi-Jiang Chen, Shidou Zhao, Yajuan Yang, Yingying Qin

EMBO J. 2024 Jul; 43(14): 3044–3071. Published online 2024 Jun 10. doi: 10.1038/s44318-024-00134-0

PMCID:: PMC11251167

Abstract Article PDF–8.7M

Select item 112091572.

Respiratory Virus-Induced PARP1 Alters DC Metabolism and Antiviral Immunity Inducing Pulmonary Immunopathology

Mohamed M. Mire, Srikanth Elesela, Susan Morris, Gabriel Corfas, Andrew Rasky, Nicholas W. Lukacs

Viruses. 2024 Jun; 16(6): 910. Published online 2024 Jun 4. doi: 10.3390/v16060910

PMCID:: PMC11209157

Abstract Article PDF–3.7M

Select item 111602123.

Parp‐1 deficiency implicated in colon and liver tumorigenesis induced by azoxymethane

Tadashige Nozaki, Hisako Fujihara, Masatoshi Watanabe, Masahiro Tsutsumi, Kentaro Nakamoto, Osamu Kusuoka, Nobuo Kamada, Hiroshi Suzuki, Hitoshi Nakagama, Takashi Sugimura, Mitsuko Masutani

Cancer Sci. 2003 Jun; 94(6): 497–500. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01472.x

PMCID:: PMC11160212

Abstract Article PDF–279K

Select item 111159414.

Functional interplay between Parp-1 and SirT1 in genome integrity and chromatin-based processes

Rosy El Ramy, Najat Magroun, Nadia Messadecq, Laurent R. Gauthier, François D. Boussin, Ullas Kolthur-Seetharam, Valérie Schreiber, Michael W. McBurney, Paolo Sassone-Corsi, Françoise Dantzer

Cell Mol Life Sci. 2009 Oct; 66(19): 3219–3234. Published online 2009 Aug 12. doi: 10.1007/s00018-009-0105-4

PMCID:: PMC11115941

Abstract Article PDF–754K

Select item 109291825.

PARP1 Promotes Heart Regeneration and Cardiomyocyte Proliferation

Jiangcheng Shu, Shu Yan, Chenhui Ju, Long Chen, Minglu Liang, Cheng Wang, Kai Huang

Int J Biol Sci. 2024; 20(5): 1602–1616. Published online 2024 Feb 11. doi: 10.7150/ijbs.85526

PMCID:: PMC10929182

Abstract Article PDF–6.1M

Select item 109176606.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108145797.

PARP1, DIDO3, and DHX9 Proteins Mutually Interact in Mouse Fibroblasts, with Effects on DNA Replication Dynamics, Senescence, and Oncogenic Transformation

Agnes Fütterer, Sara Rodriguez-Acebes, Juan Méndez, Julio Gutiérrez, Carlos Martínez-A

Cells. 2024 Jan; 13(2): 159. Published online 2024 Jan 15. doi: 10.3390/cells13020159

PMCID:: PMC10814579

Abstract Article PDF–10M

Select item 107104398.

Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide

Stefanie Krug, Manish Gupta, Pankaj Kumar, Laine Feller, Elizabeth A. Ihms, Bong Gu Kang, Geetha Srikrishna, Ted M. Dawson, Valina L. Dawson, William R. Bishai

Nat Commun. 2023; 14: 8161. Published online 2023 Dec 9. doi: 10.1038/s41467-023-43937-1

PMCID:: PMC10710439

Abstract Article PDF–1.8M

Select item 105220219.

Notch pathway mutants do not equivalently perturb mouse embryonic retinal development

Bernadett Bosze, Julissa Suarez-Navarro, Illiana Cajias, Joseph A. Brzezinski IV, Nadean L. Brown

PLoS Genet. 2023 Sep; 19(9): e1010928. Published online 2023 Sep 26. doi: 10.1371/journal.pgen.1010928

PMCID:: PMC10522021

Abstract Article PDF–5.9M

Select item 1045391610.

Poly(ADP-Ribose) Polymerase-1 Lacking Enzymatic Activity Is Not Compatible with Mouse Development

Tatiana Kamaletdinova, Wen Zong, Pavel Urbánek, Sijia Wang, Mara Sannai, Paulius Grigaravičius, Wenli Sun, Zahra Fanaei-Kahrani, Aswin Mangerich, Michael O. Hottiger, Tangliang Li, Zhao-Qi Wang

Cells. 2023 Aug; 12(16): 2078. Published online 2023 Aug 16. doi: 10.3390/cells12162078

PMCID:: PMC10453916

Abstract Article PDF–3.1M

Select item 1043301311.

Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice

David R. Garcia Castro, Joseph R. Mazuk, Erin M. Heine, Daniel Simpson, R. Seth Pinches, Caroline Lozzi, Kathryn Hoffman, Phillip Morrin, Dylan Mathis, Maria V. Lebedev, Elyse Nissley, Kang Hoo Han, Tyler Farmer, Diane E. Merry, Qiang Tong, Maria Pennuto, Heather L. Montie

iScience. 2023 Aug 18; 26(8): 107375. Published online 2023 Jul 22. doi: 10.1016/j.isci.2023.107375

PMCID:: PMC10433013

Abstract Article PDF–5.6M

Select item 1042771112.

PARP1-catalyzed PARylation of YY1 mediates endoplasmic reticulum stress in granulosa cells to determine primordial follicle activation

Wei Chen, Qiukai E, Bo Sun, Pengxue Zhang, Nan Li, Shujia Fei, Yingnan Wang, Shuting Liu, Xiaoqiu Liu, Xuesen Zhang

Cell Death Dis. 2023 Aug; 14(8): 524. Published online 2023 Aug 15. doi: 10.1038/s41419-023-05984-w

Correction in:: Cell Death Dis. 2023 Oct; 14(10): 650.

PMCID:: PMC10427711

Abstract Article PDF–6.9M

Select item 1042615413.

FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells

Weiwei Xu, Yajuan Yang, Yongze Yu, Canxin Wen, Simin Zhao, Lili Cao, Shidou Zhao, Yingying Qin, Zi-Jiang Chen

BMC Biol. 2023; 21: 174. Published online 2023 Aug 15. doi: 10.1186/s12915-023-01676-1

PMCID:: PMC10426154

Abstract Article PDF–6.6M

Select item 1040102514.

Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner

Zhengping Shao, Brian J. Lee, Hanwen Zhang, Xiaohui Lin, Chen Li, Wenxia Jiang, Napon Chirathivat, Steven Gershik, Michael M. Shen, Richard Baer, Shan Zha

Proc Natl Acad Sci U S A. 2023 Aug 1; 120(31): e2301972120. Published online 2023 Jul 24. doi: 10.1073/pnas.2301972120

PMCID:: PMC10401025

Abstract Article PDF–6.1M

Select item 1017229415.

Targeting Poly(ADP)ribose polymerase in BCR/ABL1-positive cells

Haruka Hiroki, Yuko Ishii, Jinhua Piao, Yui Namikawa, Mitsuko Masutani, Hiroaki Honda, Koshi Akahane, Takeshi Inukai, Tomohiro Morio, Masatoshi Takagi

Sci Rep. 2023; 13: 7588. Published online 2023 May 10. doi: 10.1038/s41598-023-33852-2

PMCID:: PMC10172294

Abstract Article PDF–2.6M

Select item 1001056216.

The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation

Victor A. Ruthig, Talia Hatkevich, Josiah Hardy, Matthew B. Friedersdorf, Chloé Mayère, Serge Nef, Jack D. Keene, Blanche Capel

PLoS Genet. 2023 Mar; 19(3): e1010656. Published online 2023 Mar 1. doi: 10.1371/journal.pgen.1010656

PMCID:: PMC10010562

Abstract Article PDF–2.8M

Select item 997409517.

TP63 gain-of-function mutations cause premature ovarian insufficiency by inducing oocyte apoptosis

Chengzi Huang, Simin Zhao, Yajuan Yang, Ting Guo, Hanni Ke, Xin Mi, Yingying Qin, Zi-Jiang Chen, Shidou Zhao

J Clin Invest. 2023 Mar 1; 133(5): e162315. Published online 2023 Mar 1. doi: 10.1172/JCI162315

PMCID:: PMC9974095

Abstract Article PDF–3.1M

Select item 975275318.

Morphogenesis of the female reproductive tract along antero-posterior and dorso-ventral axes is dependent on Amhr2+ mesenchyme in mice

Shuai Jia, Jillian Wilbourne, McKenna J Crossen, Fei Zhao

Biol Reprod. 2022 Dec; 107(6): 1477–1489. Published online 2022 Sep 20. doi: 10.1093/biolre/ioac179

PMCID:: PMC9752753

Abstract Article PDF–2.3M

Select item 974770819.

Role of poly(ADP-ribose) polymerase-1 in regulating human islet cell differentiation

Nidheesh Dadheech, Abhay Srivastava, Rashmi G. Shah, Girish M. Shah, Sarita Gupta

Sci Rep. 2022; 12: 21496. Published online 2022 Dec 13. doi: 10.1038/s41598-022-25405-w

PMCID:: PMC9747708

Abstract Article PDF–9.3M

Select item 964460220.

Promotion of a synthetic degradation of activated STAT6 by PARP-1 inhibition: roles of poly(ADP-ribosyl)ation, calpains and autophagy

Jeffrey Wang, Mohamed A. Ghonim, Salome V. Ibba, Hanh H. Luu, Yucel Aydin, Peter A. Greer, A. Hamid Boulares

J Transl Med. 2022; 20: 521. Published online 2022 Nov 8. doi: 10.1186/s12967-022-03715-x

PMCID:: PMC9644602

Abstract Article PDF–2.3M

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