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Items: 1 to 20 of 28

1.
Caspase-3 promotes oncogene-induced malignant transformation via EndoG-dependent Src-STAT3 phosphorylation
Chenchen Zhu, Fushun Fan, Chuan-Yuan Li, Yan Xiong, Xinjian Liu
Cell Death Dis. 2024 Jul; 15(7): 486. Published online 2024 Jul 9. doi: 10.1038/s41419-024-06884-3
PMCID:
PMC11231138
AbstractArticlePDF–3.7M
2.
Oxidative stress triggers neuronal caspase-independent death: Endonuclease G involvement in programmed cell death-type III
Gavin C. Higgins, Philip M. Beart, Phillip Nagley
Cell Mol Life Sci. 2009 Aug; 66(16): 2773–2787. Published online 2009 Jul 7. doi: 10.1007/s00018-009-0079-2
PMCID:
PMC11115579
AbstractArticlePDF–668K
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Cytoplasmic Endonuclease G promotes nonalcoholic fatty liver disease via mTORC2-AKT-ACLY and endoplasmic reticulum stress
Wenjun Wang, Junyang Tan, Xiaomin Liu, Wenqi Guo, Mengmeng Li, Xinjie Liu, Yanyan Liu, Wenyu Dai, Liubing Hu, Yimin Wang, Qiuxia Lu, Wen Xing Lee, Hong-Wen Tang, Qinghua Zhou
Nat Commun. 2023; 14: 6201. Published online 2023 Oct 4. doi: 10.1038/s41467-023-41757-x
Correction in:
Nat Commun. 2024; 15: 7167.
PMCID:
PMC10550995
AbstractArticlePDF–3.0M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response
Wenjun Wang, Jianshuang Li, Junyang Tan, Miaomiao Wang, Jing Yang, Zhi-Min Zhang, Chuanzhou Li, Alexei G. Basnakian, Hong-Wen Tang, Norbert Perrimon, Qinghua Zhou
Nat Commun. 2021; 12: 476. Published online 2021 Jan 20. doi: 10.1038/s41467-020-20780-2
PMCID:
PMC7817833
AbstractArticlePDF–6.3M
7.
Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function
Crystal M Vander Zanden, Ryan S Czarny, Ethan N Ho, Adam B Robertson, P Shing Ho
Nucleic Acids Res. 2020 Apr 17; 48(7): 3962–3974. Published online 2020 Feb 25. doi: 10.1093/nar/gkaa117
PMCID:
PMC7144941
AbstractArticlePDF–4.8M
8.
Cardiomyocyte hypertrophy induced by Endonuclease G deficiency requires reactive oxygen radicals accumulation and is inhibitable by the micropeptide humanin
Natividad Blasco, Yolanda Cámara, Estefanía Núñez, Aida Beà, Gisel Barés, Carles Forné, Marisol Ruíz-Meana, Cristina Girón, Ignasi Barba, Elena García-Arumí, David García-Dorado, Jesús Vázquez, Ramon Martí, Marta Llovera, Daniel Sanchis
Redox Biol. 2018 Jun; 16: 146–156. Published online 2018 Mar 1. doi: 10.1016/j.redox.2018.02.021
PMCID:
PMC5952880
AbstractArticlePDF–1.0M
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
IGF2BP2/IMP2 Deficient Mice Resist Obesity through enhanced translation of Ucp1 mRNA and other mRNAs encoding Mitochondrial Proteins
Ning Dai, Liping Zhao, Diedra Wrighting, Dana Krämer, Amit Majithia, Yanqun Wang, Valentin Cracan, Diego Borges-Rivera, Vamsi K. Mootha, Matthias Nahrendorf, David R. Thorburn, Liliana Minichiello, David Altshuler, Joseph Avruch
Cell Metab. Author manuscript; available in PMC 2016 Apr 7.
Published in final edited form as: Cell Metab. 2015 Apr 7; 21(4): 609–621. doi: 10.1016/j.cmet.2015.03.006
PMCID:
PMC4663978
AbstractArticlePDF–2.9M
11.
Endonuclease G preferentially cleaves 5-hydroxymethylcytosine-modified DNA creating a substrate for recombination
Adam B. Robertson, Julia Robertson, Markus Fusser, Arne Klungland
Nucleic Acids Res. 2014 Dec 1; 42(21): 13280–13293. Published online 2014 Oct 29. doi: 10.1093/nar/gku1032
PMCID:
PMC4245937
AbstractArticlePDF–546K
12.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
13.
Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions
Hong Zan, Jinsong Zhang, Ahmed Al-Qahtani, Egest J. Pone, Clayton A. White, Derrik Lee, Leman Yel, Thach Mai, Paolo Casali
Mol Immunol. Author manuscript; available in PMC 2012 Aug 5.
Published in final edited form as: Mol Immunol. 2011 Jan; 48(4): 610–622. Published online 2010 Nov 26. doi: 10.1016/j.molimm.2010.10.023
PMCID:
PMC3412130
AbstractArticlePDF–4.8M
14.
Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function
Chris McDermott-Roe, Junmei Ye, Rizwan Ahmed, Xi-Ming Sun, Anna Serafín, James Ware, Leonardo Bottolo, Phil Muckett, Xavier Cañas, Jisheng Zhang, Glenn C. Rowe, Rachel Buchan, Han Lu, Adam Braithwaite, Massimiliano Mancini, David Hauton, Ramon Martí, Elena García-Arumí, Norbert Hubner, Howard Jacob, Tadao Serikawa, Vaclav Zidek, Frantisek Papousek, Frantisek Kolar, Maria Cardona, Marisol Ruiz-Meana, David García-Dorado, Joan X Comella, Leanne E Felkin, Paul JR Barton, Zoltan Arany, Michal Pravenec, Enrico Petretto, Daniel Sanchis, Stuart A. Cook
Nature. Author manuscript; available in PMC 2012 Apr 5.
Published in final edited form as: Nature. 2011 Oct 5; 478(7367): 114–118. Published online 2011 Oct 5. doi: 10.1038/nature10490
PMCID:
PMC3189541
AbstractArticlePDF–1.7M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Endonuclease G mediates endothelial cell death induced by carbamylated LDL
Eugene O. Apostolov, Debarti Ray, Wilson M. Alobuia, Marina V. Mikhailova, Xiaoying Wang, Alexei G. Basnakian, Sudhir V. Shah
Am J Physiol Heart Circ Physiol. 2011 Jun; 300(6): H1997–H2004. Published online 2011 Apr 1. doi: 10.1152/ajpheart.01311.2010
PMCID:
PMC3119093
AbstractArticle
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
No death without life: vital functions of apoptotic effectors
L Galluzzi, N Joza, E Tasdemir, MC Maiuri, M Hengartner, JM Abrams, N Tavernarakis, J Penninger, F Madeo, G Kroemer
Cell Death Differ. Author manuscript; available in PMC 2010 Aug 9.
Published in final edited form as: Cell Death Differ. 2008 Jul; 15(7): 1113–1123. Published online 2008 Feb 29. doi: 10.1038/cdd.2008.28
PMCID:
PMC2917777
AbstractArticlePDF–347K
19.
Uptake of Foreign Nucleic Acids in Kidney Tubular Epithelial Cells Deficient in Proapoptotic Endonucleases
Timea Buzder, Xiaoyan Yin, Xiaoying Wang, Gaspar Banfalvi, Alexei G. Basnakian
DNA Cell Biol. 2009 Sep; 28(9): 435–442. doi: 10.1089/dna.2008.0850
PMCID:
PMC2903456
AbstractArticlePDF–221K
20.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M

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