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Select item 82778991.

A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke

Toshiko Yamazawa, Takuya Kobayashi, Nagomi Kurebayashi, Masato Konishi, Satoru Noguchi, Takayoshi Inoue, Yukiko U. Inoue, Ichizo Nishino, Shuichi Mori, Hiroto Iinuma, Noriaki Manaka, Hiroyuki Kagechika, Arkady Uryash, Jose Adams, Jose R. Lopez, Xiaochen Liu, Christine Diggle, Paul D. Allen, Sho Kakizawa, Keigo Ikeda, Bangzhong Lin, Yui Ikemi, Kazuto Nunomura, Shinsaku Nakagawa, Takashi Sakurai, Takashi Murayama

Nat Commun. 2021; 12: 4293. Published online 2021 Jul 13. doi: 10.1038/s41467-021-24644-1

PMCID:: PMC8277899

Abstract Article PDF–3.1M

Select item 62082912.

Malignant hyperthermia, environmental heat stress, and intracellular calcium dysregulation in a mouse model expressing the p.G2435R variant of RYR1

J.R. Lopez, V. Kaura, C.P. Diggle, P.M. Hopkins, P.D. Allen

Br J Anaesth. 2018 Oct; 121(4): 953–961. Published online 2018 Aug 10. doi: 10.1016/j.bja.2018.07.008

PMCID:: PMC6208291

Abstract Article PDF–1.2M

Select item 61621803.

Ryanodine Receptor Calcium Leak in Circulating B-lymphocytes as a Biomarker in Heart Failure

Alexander Kushnir, Gaetano Santulli, Steven R. Reiken, Ellie Coromilas, Sarah J. Godfrey, Danielle L. Brunjes, Paolo C. Colombo, Melana Yuzefpolskaya, Seth I. Sokol, Richard N. Kitsis, Andrew R. Marks

Circulation. Author manuscript; available in PMC 2019 Sep 11.

Published in final edited form as: Circulation. 2018 Sep 11; 138(11): 1144–1154. doi: 10.1161/CIRCULATIONAHA.117.032703

PMCID:: PMC6162180

Abstract Article PDF–1.1M

Select item 49763094.

Marked Sexual Dimorphism in the Role of the Ryanodine Receptor in a Model of Pain Chronification in the Rat

Luiz F. Ferrari, Eugen V. Khomula, Dionéia Araldi, Jon D. Levine

Sci Rep. 2016; 6: 31221. Published online 2016 Aug 8. doi: 10.1038/srep31221

PMCID:: PMC4976309

Abstract Article PDF–1.2M

Select item 44826445.

Divergent Activity Profiles of Type 1 Ryanodine Receptor Channels Carrying Malignant Hyperthermia and Central Core Disease Mutations in the Amino-Terminal Region

Takashi Murayama, Nagomi Kurebayashi, Toshiko Yamazawa, Hideto Oyamada, Junji Suzuki, Kazunori Kanemaru, Katsuji Oguchi, Masamitsu Iino, Takashi Sakurai

PLoS One. 2015; 10(6): e0130606. Published online 2015 Jun 26. doi: 10.1371/journal.pone.0130606

PMCID:: PMC4482644

Abstract Article PDF–1.9M

Select item 38919536.

The Environmental Neurotoxicant PCB 95 Promotes Synaptogenesis via Ryanodine Receptor-Dependent miR132 Upregulation

Adam Lesiak, Mingyan Zhu, Hao Chen, Suzanne M. Appleyard, Soren Impey, Pamela J. Lein, Gary A. Wayman

J Neurosci. 2014 Jan 15; 34(3): 717–725. doi: 10.1523/JNEUROSCI.2884-13.2014

PMCID:: PMC3891953

Abstract Article PDF–2.3M

Select item 38825487.

Overexpression of ryanodine receptor type 1 enhances mitochondrial fragmentation and Ca²⁺-induced ATP production in cardiac H9c2 myoblasts

Jin O-Uchi, Bong Sook Jhun, Stephen Hurst, Sara Bisetto, Polina Gross, Ming Chen, Sarah Kettlewell, Jongsun Park, Hideto Oyamada, Godfrey L. Smith, Takashi Murayama, Shey-Shing Sheu

Am J Physiol Heart Circ Physiol. 2013 Dec 15; 305(12): H1736–H1751. Published online 2013 Oct 11. doi: 10.1152/ajpheart.00094.2013

PMCID:: PMC3882548

Abstract Article

Select item 36364208.

Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons

Levent Kaya, Barbara Meissner, Maria Christine Riedl, Martin Muik, Christoph Schwarzer, Francesco Ferraguti, Bettina Sarg, Herbert Lindner, Rüdiger Schweigreiter, Hans-Günther Knaus, Christoph Romanin, Christine E. Bandtlow

Biochim Biophys Acta. 2013 Jun; 1833(6): 1421–1433. doi: 10.1016/j.bbamcr.2013.02.012

PMCID:: PMC3636420

Abstract Article

Select item 33097759.

Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout

Fredrik Swift, Clara Franzini-Armstrong, Leiv Øyehaug, Ulla Helene Enger, Kristin Brevik Andersson, Geir Christensen, Ole M. Sejersted, William E. Louch

Proc Natl Acad Sci U S A. 2012 Mar 6; 109(10): 3997–4001. Published online 2012 Feb 21. doi: 10.1073/pnas.1120172109

PMCID:: PMC3309775

Abstract Article PDF–1.9M

Select item 317912710.

Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca²⁺ release channel by NADPH oxidase 4

Qi-An Sun, Douglas T. Hess, Leonardo Nogueira, Sandro Yong, Dawn E. Bowles, Jerry Eu, Kenneth R. Laurita, Gerhard Meissner, Jonathan S. Stamler

Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38): 16098–16103. Published online 2011 Sep 6. doi: 10.1073/pnas.1109546108

PMCID:: PMC3179127

Abstract Article PDF–538K

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312219212.

Single Channel Characterization of the Mitochondrial Ryanodine Receptor in Heart Mitoplasts

Shin-Young Ryu, Gisela Beutner, Kathleen W. Kinnally, Robert T. Dirksen, Shey-Shing Sheu

J Biol Chem. 2011 Jun 17; 286(24): 21324–21329. Published online 2011 Apr 27. doi: 10.1074/jbc.C111.245597

PMCID:: PMC3122192

Abstract Article PDF–773K

Select item 311915013.

Upregulation of the Ca_V 1.1-ryanodine receptor complex in a rat model of critical illness myopathy

Susan D. Kraner, Qingbo Wang, Kevin R. Novak, Dongmei Cheng, David R. Cool, Junmin Peng, Mark M. Rich

Am J Physiol Regul Integr Comp Physiol. 2011 Jun; 300(6): R1384–R1391. Published online 2011 Apr 6. doi: 10.1152/ajpregu.00032.2011

PMCID:: PMC3119150

Abstract Article

Select item 308955014.

Identification of Novel Ryanodine Receptor 1 (RyR1) Protein Interaction with Calcium Homeostasis Endoplasmic Reticulum Protein (CHERP)

Timothy Ryan, Parveen Sharma, Alex Ignatchenko, David H. MacLennan, Thomas Kislinger, Anthony O. Gramolini

J Biol Chem. 2011 May 13; 286(19): 17060–17068. Published online 2011 Mar 14. doi: 10.1074/jbc.M110.197186

PMCID:: PMC3089550

Abstract Article PDF–2.1M

Select item 296417915.

Ryanodine Receptors: Structure, Expression, Molecular Details, and Function in Calcium Release

Johanna T. Lanner, Dimitra K. Georgiou, Aditya D. Joshi, Susan L. Hamilton

Cold Spring Harb Perspect Biol. 2010 Nov; 2(11): a003996. doi: 10.1101/cshperspect.a003996

PMCID:: PMC2964179

Abstract Article PDF–1.4M

Select item 291057916.

Hypernitrosylated ryanodine receptor/calcium release channels are leaky in dystrophic muscle

Andrew M. Bellinger, Steven Reiken, Christian Carlson, Marco Mongillo, Xiaoping Liu, Lisa Rothman, Stefan Matecki, Alain Lacampagne, Andrew R. Marks

Nat Med. Author manuscript; available in PMC 2010 Jul 27.

Published in final edited form as: Nat Med. 2009 Mar; 15(3): 325–330. Published online 2009 Feb 8. doi: 10.1038/nm.1916

PMCID:: PMC2910579

Abstract Article PDF–1.0M

Select item 285951517.

Identification of Functionally Segregated Sarcoplasmic Reticulum Calcium Stores in Pulmonary Arterial Smooth Muscle

Jill H. Clark, Nicholas P. Kinnear, Svetlana Kalujnaia, Gordon Cramb, Sidney Fleischer, Loice H. Jeyakumar, Frank Wuytack, A. Mark Evans

J Biol Chem. 2010 Apr 30; 285(18): 13542–13549. Published online 2010 Feb 21. doi: 10.1074/jbc.M110.101485

PMCID:: PMC2859515

Abstract Article PDF–1.1M

Select item 282634718.

Ryanodine receptors contribute to the induction of nociceptive input-evoked long-term potentiation in the rat spinal cord slice

Long-Zhen Cheng, Ning Lü, Yu-Qiu Zhang, Zhi-Qi Zhao

Mol Pain. 2010; 6: 1. Published online 2010 Jan 20. doi: 10.1186/1744-8069-6-1

PMCID:: PMC2826347

Abstract Article PDF–1.4M

Select item 273942019.

Triadin (Trisk 95) overexpression blocks excitation-contraction coupling in rat skeletal myotubes

Sophia Smida Rezgui, Stéphane Vassilopoulos, Julie Brocard, Jean Claude Platel, Alexandre Bouron, Christophe Arnoult, Sarah Oddoux, Luis Garcia, Michel De Waard, Isabelle Marty

J Biol Chem. Author manuscript; available in PMC 2009 Sep 8.

Published in final edited form as: J Biol Chem. 2005 Nov; 280(47): 39302–39308. Published online 2005 Sep 21. doi: 10.1074/jbc.M506566200

PMCID:: PMC2739420

Abstract Article

Select item 271296720.

DHPR activation underlies SR Ca²⁺ release induced by osmotic stress in isolated rat skeletal muscle fibers

James D. Pickering, Ed White, Adrian M. Duke, Derek S. Steele

J Gen Physiol. 2009 May; 133(5): 511–524. doi: 10.1085/jgp.200910191

PMCID:: PMC2712967

Abstract Article PDF–4.0M

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