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Items: 1 to 20 of 27

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
3.
Targeting RICTOR sensitizes SMAD4-negative colon cancer to irinotecan
Chen Khuan Wong, Arthur William Lambert, Sait Ozturk, Panagiotis Papageorgis, Delia Lopez, Ning Shen, Zaina Sen, Hamid Mostafavi Abdolmaleky, Balázs Győrffy, Hui Feng, Sam Thiagalingam
Mol Cancer Res. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Mol Cancer Res. 2020 Mar; 18(3): 414–423. Published online 2020 Jan 13. doi: 10.1158/1541-7786.MCR-19-0525
PMCID:
PMC7115128
AbstractArticlePDF–1.6M
4.
Regulation of TRIF-mediated innate immune response by K27-linked polyubiquitination and deubiquitination
Xin Wu, Caoqi Lei, Tian Xia, Xuan Zhong, Qing Yang, Hong-Bing Shu
Nat Commun. 2019; 10: 4115. Published online 2019 Sep 11. doi: 10.1038/s41467-019-12145-1
PMCID:
PMC6739404
AbstractArticlePDF–1.8M
5.
The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
Astrid Skjesol, Mariia Yurchenko, Korbinian Bösl, Caroline Gravastrand, Kaja Elisabeth Nilsen, Lene Melsæther Grøvdal, Federica Agliano, Francesco Patane, Germana Lentini, Hera Kim, Giuseppe Teti, Aditya Kumar Sharma, Richard K. Kandasamy, Bjørnar Sporsheim, Kristian K. Starheim, Douglas T. Golenbock, Harald Stenmark, Mary McCaffrey, Terje Espevik, Harald Husebye
PLoS Pathog. 2019 Mar; 15(3): e1007684. Published online 2019 Mar 18. doi: 10.1371/journal.ppat.1007684
PMCID:
PMC6438586
AbstractArticlePDF–4.8M
6.
SLAMF1 is required for TLR4-mediated TRAM-TRIF–dependent signaling in human macrophages
Maria Yurchenko, Astrid Skjesol, Liv Ryan, Gabriel Mary Richard, Richard Kumaran Kandasamy, Ninghai Wang, Cox Terhorst, Harald Husebye, Terje Espevik
J Cell Biol. 2018 Apr 2; 217(4): 1411–1429. doi: 10.1083/jcb.201707027
PMCID:
PMC5881497
AbstractArticlePDF–3.0M
7.
The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4
Brett Verstak, Julianne Stack, Thomas Ve, Matthew Mangan, Kathryn Hjerrild, Jannah Jeon, Rainer Stahl, Eicke Latz, Nick Gay, Bostjan Kobe, Andrew G. Bowie, Ashley Mansell
J Leukoc Biol. 2014 Sep; 96(3): 427–436. doi: 10.1189/jlb.2A0913-487R
PMCID:
PMC4632169
AbstractArticle
8.
WDFY1 mediates TLR3/4 signaling by recruiting TRIF
Yun-Hong Hu, Yu Zhang, Li-Qun Jiang, Shuai Wang, Cao-Qi Lei, Ming-Shun Sun, Hong-Bing Shu, Yu Liu
EMBO Rep. 2015 Apr; 16(4): 447–455. Published online 2015 Mar 3. doi: 10.15252/embr.201439637
PMCID:
PMC4388611
AbstractArticlePDF–1.2M
9.
Polymorphisms in TICAM2 and IL1B are associated with TB
Noémi Borsay Hall, Robert P. Igo, Jr., LaShaunda L. Malone, Barbara Truitt, Audrey Schnell, Li Tao, Brenda Okware, Mary Nsereko, Keith Chervenak, Christina Lancioni, Thomas R. Hawn, Harriet Mayanja-Kizza, Moses L. Joloba, W. Henry Boom, Catherine M. Stein, the Tuberculosis Research Unit (TBRU)
Genes Immun. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: Genes Immun. 2015 Mar; 16(2): 127–133. Published online 2014 Dec 18. doi: 10.1038/gene.2014.77
PMCID:
PMC4352113
AbstractArticlePDF–353K
10.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
11.
TRAM is required for TLR2 endosomal signaling to type I IFN induction
Julianne Stack, Sarah L. Doyle, Dympna J. Connolly, Line S. Reinert, Kate M. O’Keeffe, Rachel M. McLoughlin, Søren R. Paludan, Andrew G. Bowie
J Immunol. Author manuscript; available in PMC 2015 Jun 15.
Published in final edited form as: J Immunol. 2014 Dec 15; 193(12): 6090–6102. Published online 2014 Nov 10. doi: 10.4049/jimmunol.1401605
PMCID:
PMC4258402
AbstractArticlePDF–2.6M
12.
The TIR-Domain Containing Adaptor TRAM Is Required for TLR7 Mediated RANTES Production
Enda Shevlin, Sinéad M. Miggin
PLoS One. 2014; 9(9): e107141. Published online 2014 Sep 11. doi: 10.1371/journal.pone.0107141
PMCID:
PMC4161432
AbstractArticlePDF–1.0M
13.
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
Jonathan C Kagan, Tian Su, Tiffany Horng, Amy Chow, Shizuo Akira, Ruslan Medzhitov
Nat Immunol. Author manuscript; available in PMC 2014 Jul 28.
Published in final edited form as: Nat Immunol. 2008 Apr; 9(4): 361–368. Published online 2008 Feb 24. doi: 10.1038/ni1569
PMCID:
PMC4112825
AbstractArticlePDF–1013K
14.
Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling
Yoshiaki Enokizono, Hiroyuki Kumeta, Kenji Funami, Masataka Horiuchi, Joy Sarmiento, Kazuo Yamashita, Daron M. Standley, Misako Matsumoto, Tsukasa Seya, Fuyuhiko Inagaki
Proc Natl Acad Sci U S A. 2013 Dec 3; 110(49): 19908–19913. Published online 2013 Nov 19. doi: 10.1073/pnas.1222811110
PMCID:
PMC3856793
AbstractArticlePDF–1.4M
15.
Human Cytomegalovirus Induces TLR4 Signaling Components in Monocytes Altering TIRAP, TRAM and Downstream Interferon-Beta and TNF-Alpha Expression
Kok-Hooi Yew, Cory Carpenter, R. Scott Duncan, Christopher J. Harrison
PLoS One. 2012; 7(9): e44500. Published online 2012 Sep 7. doi: 10.1371/journal.pone.0044500
PMCID:
PMC3436894
AbstractArticlePDF–1.4M
16.
TRAM Is Involved in IL-18 Signaling and Functions as a Sorting Adaptor for MyD88
Hidenori Ohnishi, Hidehito Tochio, Zenichiro Kato, Norio Kawamoto, Takeshi Kimura, Kazuo Kubota, Takahiro Yamamoto, Tatsuyoshi Funasaka, Hiroshi Nakano, Richard W. Wong, Masahiro Shirakawa, Naomi Kondo
PLoS One. 2012; 7(6): e38423. Published online 2012 Jun 7. doi: 10.1371/journal.pone.0038423
PMCID:
PMC3369926
AbstractArticlePDF–2.2M
17.
Toward an understanding of the protein interaction network of the human liver
Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang
Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67
Correction in:
Mol Syst Biol. 2017 Dec; 13(12): 965.
PMCID:
PMC3261708
AbstractArticlePDF–2.0M
18.
Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production
Shitao Li, Lingyan Wang, Michael Berman, Young-Yun Kong, Martin E. Dorf
Immunity. Author manuscript; available in PMC 2012 Sep 23.
Published in final edited form as: Immunity. 2011 Sep 23; 35(3): 426–440. Published online 2011 Sep 8. doi: 10.1016/j.immuni.2011.06.014
Correction in:
volume 35 on page 647
PMCID:
PMC3253658
AbstractArticlePDF–4.2M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
TIRAP, an Adaptor Protein for TLR2/4, Transduces a Signal from RAGE Phosphorylated upon Ligand Binding
Masakiyo Sakaguchi, Hitoshi Murata, Ken-ichi Yamamoto, Tomoyuki Ono, Yoshihiko Sakaguchi, Akira Motoyama, Toshihiko Hibino, Ken Kataoka, Nam-ho Huh
PLoS One. 2011; 6(8): e23132. Published online 2011 Aug 1. doi: 10.1371/journal.pone.0023132
PMCID:
PMC3148248
AbstractArticlePDF–741K

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