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Items: 1 to 20 of 23

1.
Genome-wide association study implicates CHRNA2 in cannabis use disorder
Ditte Demontis, Veera Manikandan Rajagopal, Thorgeir E. Thorgeirsson, Thomas D. Als, Jakob Grove, Kalle Leppälä, Daniel F. Gudbjartsson, Jonatan Pallesen, Carsten Hjorthøj, Gunnar W. Reginsson, Thorarinn Tyrfingsson, Valgerdur Runarsdottir, Per Qvist, Jane Hvarregaard Christensen, Jonas Bybjerg-Grauholm, Marie Bækvad-Hansen, Laura M. Huckins, Eli A. Stahl, Allan Timmermann, Esben Agerbo, David M. Hougaard, Thomas Werge, Ole Mors, Preben Bo Mortensen, Merete Nordentoft, Mark J. Daly, Hreinn Stefansson, Kari Stefansson, Mette Nyegaard, Anders D. Børglum
Nat Neurosci. Author manuscript; available in PMC 2020 Oct 30.
Published in final edited form as: Nat Neurosci. 2019 Jul; 22(7): 1066–1074. Published online 2019 Jun 17. doi: 10.1038/s41593-019-0416-1
PMCID:
PMC7596896
AbstractArticlePDF–795K
2.
An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling
Heejin Jun, Hui Yu, Jianke Gong, Juan Jiang, Xiaona Qiao, Eric Perkey, Dong-il Kim, Margo P. Emont, Alexander G. Zestos, Jung-Sun Cho, Jianfeng Liu, Robert T. Kennedy, Ivan Maillard, X.Z. Shawn Xu, Jun Wu
Nat Med. Author manuscript; available in PMC 2018 Nov 21.
Published in final edited form as: Nat Med. 2018 Jun; 24(6): 814–822. Published online 2018 May 21. doi: 10.1038/s41591-018-0032-8
PMCID:
PMC5992032
AbstractArticlePDF–1.1M
3.
Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamer
Nikolaos Kouvatsos, Petros Giastas, Dafni Chroni-Tzartou, Cornelia Poulopoulou, Socrates J. Tzartos
Proc Natl Acad Sci U S A. 2016 Aug 23; 113(34): 9635–9640. Published online 2016 Aug 4. doi: 10.1073/pnas.1602619113
PMCID:
PMC5003238
AbstractArticlePDF–1.0M
4.
The Contribution of Rare and Common Variants in 30 Genes to Risk Nicotine Dependence
Jiekun Yang, Shaolin Wang, Zhongli Yang, Colin A. Hodgkinson, Polina Iarikova, Jennie Z. Ma, Thomas J. Payne, David Goldman, Ming D. Li
Mol Psychiatry. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: Mol Psychiatry. 2015 Nov; 20(11): 1467–1478. Published online 2014 Dec 2. doi: 10.1038/mp.2014.156
PMCID:
PMC4452458
AbstractArticlePDF–753K
5.
Nocturnal frontal lobe epilepsy with paroxysmal arousals due to CHRNA2 loss of function
Valerio Conti, Patrizia Aracri, Laura Chiti, Simone Brusco, Francesco Mari, Carla Marini, Maria Albanese, Angela Marchi, Claudio Liguori, Fabio Placidi, Andrea Romigi, Andrea Becchetti, Renzo Guerrini
Neurology. 2015 Apr 14; 84(15): 1520–1528. doi: 10.1212/WNL.0000000000001471
PMCID:
PMC4408286
AbstractArticlePDF–1.0M
6.
Two rare variations, D478N and D478E, that occur at the same amino acid residue in nicotinic acetylcholine receptor (nAChR) α2 subunit influence nAChR function
Bhagirathi Dash, Ming D. Li
Neuropharmacology. Author manuscript; available in PMC 2015 Oct 1.
Published in final edited form as: Neuropharmacology. 2014 Oct; 85: 471–481. Published online 2014 Jun 17. doi: 10.1016/j.neuropharm.2014.05.014
PMCID:
PMC4135378
AbstractArticlePDF–1.9M
7.
Significant Associations of CHRNA2 and CHRNA6 with Nicotine Dependence in European American and African American Populations
Shaolin Wang, Andrew van der Vaart, Qing Xu, Chamindi Seneviratne, Ovide F. Pomerleau, Cynthia S. Pomerleau, Thomas J. Payne, Jennie Z. Ma, Ming D. Li
Hum Genet. Author manuscript; available in PMC 2015 May 1.
Published in final edited form as: Hum Genet. 2014 May; 133(5): 575–586. Published online 2013 Nov 20. doi: 10.1007/s00439-013-1398-9
PMCID:
PMC3988215
AbstractArticlePDF–551K
8.
A signal peptide missense mutation associated with nicotine dependence alters α2*-nicotinic acetylcholine receptor function
Bhagirathi Dash, Ronald J. Lukas, Ming D. Li
Neuropharmacology. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: Neuropharmacology. 2014 Apr; 79: 715–725. Published online 2014 Jan 24. doi: 10.1016/j.neuropharm.2014.01.021
PMCID:
PMC3984001
AbstractArticlePDF–2.7M
9.
Effect of Neuronal Nicotinic Acetylcholine Receptor Genes (CHRN) on Longitudinal Cigarettes per Day in Adolescents and Young Adults
Dale S. Cannon, Robin J. Mermelstein, Donald Hedeker, Hilary Coon, Edwin H. Cook, William M. McMahon, Cindy Hamil, Diane Dunn, Robert B. Weiss
Nicotine Tob Res. 2014 Feb; 16(2): 137–144. Published online 2013 Aug 13. doi: 10.1093/ntr/ntt125
PMCID:
PMC3880230
AbstractArticlePDF–669K
10.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
11.
Resequencing of Nicotinic Acetylcholine Receptor Genes and Association of Common and Rare Variants with the Fagerström Test for Nicotine Dependence
Jennifer Wessel, Sarah M McDonald, David A Hinds, Renee P Stokowski, Harold S Javitz, Michael Kennemer, Ruth Krasnow, William Dirks, Jill Hardin, Steven J Pitts, Martha Michel, Lisa Jack, Dennis G Ballinger, Jennifer B McClure, Gary E Swan, Andrew W Bergen
Neuropsychopharmacology. 2010 Nov; 35(12): 2392–2402. Published online 2010 Aug 25. doi: 10.1038/npp.2010.120
PMCID:
PMC3055324
AbstractArticlePDF–441K
12.
Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis
Anna C Need, Richard SE Keefe, Dongliang Ge, Iris Grossman, Sam Dickson, Joseph P McEvoy, David B Goldstein
Eur J Hum Genet. 2009 Jul; 17(7): 946–957. Published online 2009 Jan 21. doi: 10.1038/ejhg.2008.264
PMCID:
PMC2986499
AbstractArticlePDF–172K
13.
Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans
Nancy L. Saccone, Tae-Hwi Schwantes-An, Jen C. Wang, Richard A. Grucza, Naomi Breslau, Dorothy Hatsukami, Eric O. Johnson, John P. Rice, Alison M. Goate, Laura J. Bierut
Genes Brain Behav. Author manuscript; available in PMC 2011 Oct 1.
Published in final edited form as: Genes Brain Behav. 2010 Oct; 9(7): 741–750. Published online 2010 Jul 22. doi: 10.1111/j.1601-183X.2010.00608.x
PMCID:
PMC2970751
AbstractArticlePDF–333K
14.
A large-scale candidate-gene association study of age at menarche and age at natural menopause
Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter
Hum Genet. Author manuscript; available in PMC 2010 Nov 1.
Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4
PMCID:
PMC2967297
AbstractArticlePDF–84K
15.
Multiple Distinct Risk Loci for Nicotine Dependence Identified by Dense Coverage of the Complete Family of Nicotinic Receptor Subunit (CHRN) Genes
Nancy L. Saccone, Scott F. Saccone, Anthony L. Hinrichs, Jerry A. Stitzel, Weimin Duan, Michele L. Pergadia, Arpana Agrawal, Naomi Breslau, Richard A. Grucza, Dorothy Hatsukami, Eric O. Johnson, Pamela A. F. Madden, Gary E. Swan, Jen C. Wang, Alison M. Goate, John P. Rice, Laura J. Bierut
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2010 Jun 5.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2009 Jun 5; 150B(4): 453–466. doi: 10.1002/ajmg.b.30828
PMCID:
PMC2693307
AbstractArticlePDF–1.6M
16.
Examination of the Nicotine Dependence (NICSNP) Consortium findings in the Iowa adoption studies population
Robert A. Philibert, Alexandre Todorov, Allan Andersen, Nancy Hollenbeck, Tracy Gunter, Andrew Heath, Pamela Madden
Nicotine Tob Res. 2009 Mar; 11(3): 286–292. Published online 2009 Mar 23. doi: 10.1093/ntr/ntn034
PMCID:
PMC2666378
AbstractArticlePDF–118K
17.
Identification of Pharmacogenetic Markers in Smoking Cessation Therapy
Daniel F. Heitjan, Mengye Guo, Riju Ray, E. Paul Wileyto, Leonard H. Epstein, Caryn Lerman
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2009 Sep 5.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5; 147B(6): 712–719. doi: 10.1002/ajmg.b.30669
PMCID:
PMC2655206
AbstractArticlePDF–527K
18.
No Evidence for Association between 19 Cholinergic Genes and Bipolar Disorder
Jiajun Shi, Eiji Hattori, Hongwei Zou, Judith A. Badner, Susan L. Christian, Elliot S. Gershon, Chunyu Liu
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2008 Oct 30.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2007 Sep 5; 144B(6): 715–723. doi: 10.1002/ajmg.b.30417
PMCID:
PMC2576477
AbstractArticlePDF–319K
19.
Association of candidate genes with antisocial drug dependence in adolescents
Robin P. Corley, Joanna S. Zeiger, Thomas Crowley, Marissa A. Ehringer, John K. Hewitt, Christian J. Hopfer, Jeffrey Lessem, Matthew B. McQueen, Soo Hyun Rhee, Andrew Smolen, Michael C. Stallings, Susan E. Young, Kenneth Krauter
Drug Alcohol Depend. Author manuscript; available in PMC 2009 Jul 1.
Published in final edited form as: Drug Alcohol Depend. 2008 Jul 1; 96(1-2): 90–98. Published online 2008 Apr 1. doi: 10.1016/j.drugalcdep.2008.02.004
PMCID:
PMC2574676
AbstractArticlePDF–79K
20.
Increased Sensitivity of the Neuronal Nicotinic Receptor α2 Subunit Causes Familial Epilepsy with Nocturnal Wandering and Ictal Fear
Paolo Aridon, Carla Marini, Chiara Di Resta, Elisa Brilli, Maurizio De Fusco, Fausta Politi, Elena Parrini, Irene Manfredi, Tiziana Pisano, Dario Pruna, Giulia Curia, Carlo Cianchetti, Massimo Pasqualetti, Andrea Becchetti, Renzo Guerrini, Giorgio Casari
Am J Hum Genet. 2006 Aug; 79(2): 342–350. Published online 2006 Jun 26. doi: 10.1086/506459
PMCID:
PMC1559502
AbstractArticlePDF–1.3M

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