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Items: 1 to 20 of 292

1.
Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
David Jetton, Hayley I. Muendlein, Wilson M. Connolly, Zoie Magri, Irina Smirnova, Rebecca Batorsky, Joan Mecsas, Alexei Degterev, Alexander Poltorak
Cell Rep. Author manuscript; available in PMC 2024 Oct 10.
Published in final edited form as: Cell Rep. 2024 Aug 27; 43(8): 114641. Published online 2024 Aug 17. doi: 10.1016/j.celrep.2024.114641
PMCID:
PMC11465231
AbstractArticlePDF–2.9M
2.
ASIC1/RIP1 accelerates atherosclerosis via disrupting lipophagy
Yuan-Mei Wang, Huang Tang, Ya-Jie Tang, Juan Liu, Yu-Fang Yin, Ya-Ling Tang, Yao-Guang Feng, Hong-Feng Gu
J Adv Res. 2024 Sep; 63: 195–206. Published online 2023 Nov 4. doi: 10.1016/j.jare.2023.11.004
PMCID:
PMC11379975
AbstractArticlePDF–4.2M
3.
Cryptosporidium impacts epithelial turnover and is resistant to induced death of the host cell
Bethan A. Wallbank, Ryan D. Pardy, Igor E. Brodsky, Christopher A. Hunter, Boris Striepen
mBio. 2024 Aug; 15(8): e01720-24. Published online 2024 Jul 12. doi: 10.1128/mbio.01720-24
PMCID:
PMC11323733
AbstractArticlePDF–3.9M
4.
RIPK1 is dispensable for cell death regulation in β-cells during hyperglycemia
Önay Veli, Öykü Kaya, Ana Beatriz Varanda, Ximena Hildebrandt, Peng Xiao, Yann Estornes, Matea Poggenberg, Yuan Wang, Manolis Pasparakis, Mathieu J.M. Bertrand, Henning Walczak, Alessandro Annibaldi, Alessandra K. Cardozo, Nieves Peltzer
Mol Metab. 2024 Sep; 87: 101988. Published online 2024 Jul 14. doi: 10.1016/j.molmet.2024.101988
PMCID:
PMC11295703
AbstractArticlePDF–3.6M
5.
The Interferon-Stimulated Gene RIPK1 Regulates Cancer Cell Intrinsic and Extrinsic Resistance to Immune Checkpoint Blockade
Lisa Cucolo, Qingzhou Chen, Jingya Qiu, Yongjun Yu, Max Klapholz, Krista Budinich, Zhaojun Zhang, Yue Shao, Igor E. Brodsky, Martha S. Jordan, D. Gary Gilliland, Nancy R. Zhang, Junwei Shi, Andy J. Minn
Immunity. Author manuscript; available in PMC 2024 Jul 31.
Published in final edited form as: Immunity. 2022 Apr 12; 55(4): 671–685.e10. doi: 10.1016/j.immuni.2022.03.007
PMCID:
PMC11289737
AbstractArticlePDF–3.5M
6.
RIPK1 protects naive and regulatory T cells from TNFR1-induced apoptosis
Jelle Huysentruyt, Wolf Steels, Mario Ruiz Perez, Bruno Verstraeten, Mike Vadi, Tatyana Divert, Kayleigh Flies, Nozomi Takahashi, Bart N. Lambrecht, Wim Declercq, Tom Vanden Berghe, Jonathan Maelfait, Peter Vandenabeele, Peter Tougaard
Cell Death Differ. 2024 Jun; 31(6): 820–832. Published online 2024 May 11. doi: 10.1038/s41418-024-01301-w
PMCID:
PMC11164875
AbstractArticlePDF–4.2M
7.
The modular nature of apoptotic signaling proteins
K. Hofmann
Cell Mol Life Sci. 1999 Jul; 55(8-9): 1113–1128. doi: 10.1007/s000180050361
PMCID:
PMC11146888
AbstractArticlePDF–923K
8.
Protective role of RIPK1 scaffolding against HDV-induced hepatocyte cell death and the significance of cytokines in mice
Gracián Camps, Sheila Maestro, Laura Torella, Diego Herrero, Carla Usai, Martin Bilbao-Arribas, Ana Aldaz, Cristina Olagüe, Africa Vales, Lester Suárez-Amarán, Rafael Aldabe, Gloria Gonzalez-Aseguinolaza
PLoS Pathog. 2024 May; 20(5): e1011749. Published online 2024 May 13. doi: 10.1371/journal.ppat.1011749
PMCID:
PMC11115361
AbstractArticlePDF–2.5M
9.
ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1
Margaret Solon, Nianfeng Ge, Shannon Hambro, Susan Haller, Jian Jiang, Miriam Baca, Jessica Preston, Allie Maltzman, Katherine E. Wickliffe, Yuxin Liang, Rohit Reja, Dorothee Nickles, Kim Newton, Joshua D. Webster
Cell Death Differ. 2024 May; 31(5): 672–682. Published online 2024 Mar 28. doi: 10.1038/s41418-024-01286-6
PMCID:
PMC11093969
AbstractArticlePDF–5.5M
10.
Binding of RAGE and RIPK1 induces cognitive deficits in chronic hyperglycemia‐derived neuroinflammation
Xiaoyan Zhou, Yandong Zhu, Lin Gao, Yan Li, Hui Li, Chengyu Huang, Yan Liu, Ankang Hu, Changjiang Ying, Yuanjian Song
CNS Neurosci Ther. 2024 Mar; 30(3): e14449. Published online 2023 Sep 4. doi: 10.1111/cns.14449
PMCID:
PMC10916433
AbstractArticlePDF–26M
11.
RIPK1 activation in Mecp2-deficient microglia promotes inflammation and glutamate release in RTT
Ze Cao, Xia Min, Xingxing Xie, Maoqing Huang, Yingying Liu, Weimin Sun, Guifang Xu, Miao He, Kaiwen He, Ying Li, Junying Yuan
Proc Natl Acad Sci U S A. 2024 Feb 6; 121(6): e2320383121. Published online 2024 Jan 30. doi: 10.1073/pnas.2320383121
PMCID:
PMC10861890
AbstractArticlePDF–10M
12.
IKKε and TBK1 prevent RIPK1 dependent and independent inflammation
Remzi Onur Eren, Göksu Gökberk Kaya, Robin Schwarzer, Manolis Pasparakis
Nat Commun. 2024; 15: 130. Published online 2024 Jan 2. doi: 10.1038/s41467-023-44372-y
PMCID:
PMC10761900
AbstractArticlePDF–6.9M
13.
Receptor-interacting protein 1 and 3 kinase activity are required for high-fat diet induced liver injury in mice
Xiaoqin Wu, Rakesh K. Arya, Emily Huang, Megan R. McMullen, Laura E. Nagy
Front Endocrinol (Lausanne) 2023; 14: 1267996. Published online 2023 Dec 15. doi: 10.3389/fendo.2023.1267996
PMCID:
PMC10757356
AbstractArticlePDF–9.5M
14.
Excessive apoptosis of Rip1‐deficient T cells leads to premature aging
Lingxia Wang, Xixi Zhang, Haiwei Zhang, Kaili Lu, Ming Li, Xiaoming Li, Yangjing Ou, Xiaoming Zhao, Xiaoxia Wu, Xuanhui Wu, Jianling Liu, Mingyan Xing, Han Liu, Yue Zhang, Yongchang Tan, Fang Li, Xiaoxue Deng, Jiangshan Deng, Xiaojie Zhang, Jinbao Li, Yuwu Zhao, Qiurong Ding, Haikun Wang, Xiuzhe Wang, Yan Luo, Ben Zhou, Haibing Zhang
EMBO Rep. 2023 Dec; 24(12): e57925. Published online 2023 Nov 15. doi: 10.15252/embr.202357925
PMCID:
PMC10702839
AbstractArticlePDF–3.1M
15.
cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation
Fabian Schorn, J Paul Werthenbach, Mattes Hoffmann, Mila Daoud, Johanna Stachelscheid, Lars M Schiffmann, Ximena Hildebrandt, Su Ir Lyu, Nieves Peltzer, Alexander Quaas, Domagoj Vucic, John Silke, Manolis Pasparakis, Hamid Kashkar
EMBO J. 2023 Nov; 42(22): e113614. Published online 2023 Oct 4. doi: 10.15252/embj.2023113614
PMCID:
PMC10646551
AbstractArticlePDF–3.3M
16.
RIPK1 deficiency prevents thymic NK1.1 expression and subsequent iNKT cell development
Thomas Hägglöf, Raksha Parthasarathy, Nathaniel Liendo, Elizabeth A. Dudley, Elizabeth A. Leadbetter
Front Immunol. 2023; 14: 1103591. Published online 2023 Oct 30. doi: 10.3389/fimmu.2023.1103591
PMCID:
PMC10642909
AbstractArticlePDF–6.6M
17.
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation
Tao Zhang, Daichao Xu, Jianping Liu, Min Wang, Li-Juan Duan, Min Liu, Huyan Meng, Yuan Zhuang, Huibing Wang, Yingnan Wang, Mingming Lv, Zhengyi Zhang, Jia Hu, Linyu Shi, Rui Guo, Xingxing Xie, Hui Liu, Emily Erickson, Yaru Wang, Wenyu Yu, Fabin Dang, Dongxian Guan, Cong Jiang, Xiaoming Dai, Hiroyuki Inuzuka, Peiqiang Yan, Jingchao Wang, Mrigya Babuta, Gewei Lian, Zhenbo Tu, Ji Miao, Gyongyi Szabo, Guo-Hua Fong, Antoine E. Karnoub, Yu-Ru Lee, Lifeng Pan, William G. Kaelin, Jr., Junying Yuan, Wenyi Wei
Nat Cell Biol. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Nat Cell Biol. 2023 Jul; 25(7): 950–962. Published online 2023 Jul 3. doi: 10.1038/s41556-023-01170-4
PMCID:
PMC10617019
AbstractArticlePDF–8.3M
18.
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1
Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily Erickson, Alissandra L. Hillis, Christian C. Dibble, John M. Asara, Gyongy Szabo, Piotr Sicinski, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J. Shaw, Junying Yuan, Wenyi Wei
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Jun 30; 380(6652): 1372–1380. Published online 2023 Jun 29. doi: 10.1126/science.abn1725
PMCID:
PMC10617018
AbstractArticlePDF–2.3M
19.
A novel RIP1-mediated canonical WNT signaling pathway that promotes colorectal cancer metastasis via β -catenin stabilization-induced EMT
A-Ram Kang, Jung-Lim Kim, YoungHa Kim, Sanghee Kang, Sang-Cheul Oh, Jong Kuk Park
Cancer Gene Ther. 2023; 30(10): 1403–1413. Published online 2023 Jul 27. doi: 10.1038/s41417-023-00647-6
PMCID:
PMC10581897
AbstractArticlePDF–2.9M
20.
Polarity protein AF6 functions as a modulator of necroptosis by regulating ubiquitination of RIPK1 in liver diseases
Wang Xinyu, Wen Qian, Wu Yanjun, Kong Jingwen, Xu Keying, Jiao Jiazheng, Zhang Haibing, Wang Kai, Xu Xiao, Zhan Lixing
Cell Death Dis. 2023 Oct; 14(10): 673. Published online 2023 Oct 12. doi: 10.1038/s41419-023-06170-8
PMCID:
PMC10570300
AbstractArticlePDF–4.2M

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