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Items: 1 to 20 of 102

1.
Profibrogenic role of IL-15 through IL-15 receptor alpha-mediated trans-presentation in the carbon tetrachloride-induced liver fibrosis model
Maryse Cloutier, Bhavesh Variya, Sara Ali Akbari, Fjolla Rexhepi, Subburaj Ilangumaran, Sheela Ramanathan
Front Immunol. 2024; 15: 1404891. Published online 2024 Jun 11. doi: 10.3389/fimmu.2024.1404891
PMCID:
PMC11196400
AbstractArticlePDF–4.8M
2.
MDM2 inhibition enhances immune checkpoint inhibitor efficacy by increasing IL-15 and MHC class II production
Marlene Langenbach, Sophie Giesler, Stefan Richtsfeld, Sara Costa-Pereira, Lukas Rindlisbacher, Tobias Wertheimer, Lukas M. Braun, Geoffroy Andrieux, Sandra Duquesne, Dietmar Pfeifer, Nadine M. Woessner, Hans D. Menssen, Sanaz Taromi, Justus Duyster, Melanie Börries, Tilman Brummer, Bruce R. Blazar, Susana Minguet, Patrick Turko, Mitchell P. Levesque, Burkhard Becher, Robert Zeiser
Mol Cancer Res. Author manuscript; available in PMC 2024 Feb 1.
Published in final edited form as: Mol Cancer Res. 2023 Aug 1; 21(8): 849–864. doi: 10.1158/1541-7786.MCR-22-0898
PMCID:
PMC10524444
AbstractArticlePDF–3.0M
3.
In vivo availability of the cytokine IL-7 constrains the survival and homeostasis of peripheral iNKT cells
Joo-Young Park, Hee Yeun Won, Devon T. DiPalma, Hye Kyung Kim, Tae-Hyoun Kim, Can Li, Noriko Sato, Changwan Hong, Ninan Abraham, Ronald E. Gress, Jung-Hyun Park
Cell Rep. Author manuscript; available in PMC 2023 Jun 26.
Published in final edited form as: Cell Rep. 2022 Jan 11; 38(2): 110219. doi: 10.1016/j.celrep.2021.110219
PMCID:
PMC10292121
AbstractArticlePDF–2.8M
4.
CXCR6 Positions Cytotoxic T Cells to Receive Critical Survival Signals in the Tumor Microenvironment
Mauro Di Pilato, Raphael Kfuri-Rubens, Jasper N. Pruessmann, Aleksandra J. Ozga, Marius Messemaker, Bruno L. Cadilha, Ramya Sivakumar, Chiara Cianciaruso, Ross D. Warner, Francesco Marangoni, Esteban Carrizosa, Stefanie Lesch, James Billingsley, Daniel Perez-Ramos, Fidel Zavala, Esther Rheinbay, Andrew D. Luster, Michael Y. Gerner, Sebastian Kobold, Mikael J. Pittet, Thorsten R. Mempel
Cell. Author manuscript; available in PMC 2022 Aug 19.
Published in final edited form as: Cell. 2021 Aug 19; 184(17): 4512–4530.e22. Published online 2021 Aug 2. doi: 10.1016/j.cell.2021.07.015
PMCID:
PMC8719451
AbstractArticlePDF–4.3M
5.
IL-15 Prevents Renal Fibrosis by Inhibiting Collagen Synthesis: A New Pathway in Chronic Kidney Disease?
Aurore Devocelle, Lola Lecru, Sophie Ferlicot, Thomas Bessede, Jean-Jacques Candelier, Julien Giron-Michel, Hélène François
Int J Mol Sci. 2021 Nov; 22(21): 11698. Published online 2021 Oct 28. doi: 10.3390/ijms222111698
PMCID:
PMC8583733
AbstractArticlePDF–4.2M
6.
Natural killer cells and dendritic epidermal γδ T cells orchestrate type 1 conventional DC spatiotemporal repositioning toward CD8+ T cells
Sonia Ghilas, Marc Ambrosini, Jean-Charles Cancel, Carine Brousse, Marion Massé, Hugues Lelouard, Marc Dalod, Karine Crozat
iScience. 2021 Sep 24; 24(9): 103059. Published online 2021 Aug 28. doi: 10.1016/j.isci.2021.103059
PMCID:
PMC8449251
AbstractArticlePDF–4.0M
7.
Skeletal Muscle O-GlcNAc Transferase Action on Global Metabolism Is Partially Mediated Through Interleukin-15
Morgan D. Zumbaugh, Con-Ning Yen, Jocelyn S. Bodmer, Hao Shi, David E. Gerrard
Front Physiol. 2021; 12: 682052. Published online 2021 Jul 13. doi: 10.3389/fphys.2021.682052
PMCID:
PMC8313823
AbstractArticlePDF–2.1M
8.
Rapid Depletion of Intratumoral Regulatory T cells Induces Synchronized CD8 T and NK Cell Activation and IFN-γ-dependent Tumor Vessel Regression
Yutaka Kurebayashi, Colleen P. Olkowski, Kelly C. Lane, Olga V. Vasalatiy, Biying C. Xu, Ryuhei Okada, Aki Furusawa, Peter L. Choyke, Hisataka Kobayashi, Noriko Sato
Cancer Res. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: Cancer Res. 2021 Jun 1; 81(11): 3092–3104. Published online 2021 Feb 11. doi: 10.1158/0008-5472.CAN-20-2673
PMCID:
PMC8178213
AbstractArticlePDF–1.7M
9.
Thymic Epithelial Cell-Derived IL-15 and IL-15 Receptor α Chain Foster Local Environment for Type 1 Innate Like T Cell Development
Huishan Tao, Lei Li, Nan-Shih Liao, Kimberly S. Schluns, Shirley Luckhart, John W. Sleasman, Xiao-Ping Zhong
Front Immunol. 2021; 12: 623280. Published online 2021 Mar 1. doi: 10.3389/fimmu.2021.623280
PMCID:
PMC7957058
AbstractArticlePDF–3.5M
10.
IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models
Siqi Guo, Ronald B. Smeltz, Anthony Nanajian, Richard Heller
Front Immunol. 2020; 11: 614667. Published online 2021 Feb 8. doi: 10.3389/fimmu.2020.614667
PMCID:
PMC7897681
AbstractArticlePDF–3.2M
11.
c-FLIP is crucial for IL-7/IL-15-dependent NKp46+ ILC development and protection from intestinal inflammation in mice
Ute Bank, Katrin Deiser, Carlos Plaza-Sirvent, Lisa Osbelt, Amelie Witte, Laura Knop, Rebecca Labrenz, Robert Jänsch, Felix Richter, Aindrila Biswas, Ana C. Zenclussen, Eric Vivier, Chiara Romagnani, Anja A. Kühl, Ildiko R. Dunay, Till Strowig, Ingo Schmitz, Thomas Schüler
Nat Commun. 2020; 11: 1056. Published online 2020 Feb 26. doi: 10.1038/s41467-020-14782-3
PMCID:
PMC7044440
AbstractArticlePDF–3.2M
12.
Effect of Interleukin-15 Receptor Alpha Ablation on the Metabolic Responses to Moderate Exercise Simulated by in vivo Isometric Muscle Contractions
Emanuele Loro, Cholsoon Jang, William J. Quinn, III, Joseph A. Baur, Zoltan P. Arany, Tejvir S. Khurana
Front Physiol. 2019; 10: 1439. Published online 2019 Nov 26. doi: 10.3389/fphys.2019.01439
PMCID:
PMC6901992
AbstractArticlePDF–6.0M
13.
Anti-tumor T-cell homeostatic activation is uncoupled from homeostatic inhibition by checkpoint blockade
Netonia Marshall, Keino Hutchinson, Thomas U Marron, Mark Aleynick, Linda Hammerich, Ranjan Upadhyay, Judit Svensson-Arvelund, Brian D Brown, Miriam Merad, Joshua D Brody
Cancer Discov. Author manuscript; available in PMC 2020 May 1.
Published in final edited form as: Cancer Discov. 2019 Nov; 9(11): 1520–1537. Published online 2019 Aug 2. doi: 10.1158/2159-8290.CD-19-0391
PMCID:
PMC6825548
AbstractArticlePDF–2.8M
14.
NK Cell IL-10 Production Requires IL-15 and IL-10 Driven STAT3 Activation
Sarah E. Clark, Kristina S. Burrack, Stephen C. Jameson, Sara E. Hamilton, Laurel L. Lenz
Front Immunol. 2019; 10: 2087. Published online 2019 Sep 4. doi: 10.3389/fimmu.2019.02087
PMCID:
PMC6736993
AbstractArticlePDF–3.7M
15.
The deubiquitinase Otub1 controls the activation of CD8 T cells and NK cells by regulating IL-15-mediated priming
Xiaofei Zhou, Jiayi Yu, Xuhong Cheng, Baoyu Zhao, Ganiraju C Manyam, Li Zhang, Kimberly Schluns, Pingwei Li, Jing Wang, Shao-Cong Sun
Nat Immunol. Author manuscript; available in PMC 2019 Dec 10.
Published in final edited form as: Nat Immunol. 2019 Jul; 20(7): 879–889. Published online 2019 Jun 10. doi: 10.1038/s41590-019-0405-2
PMCID:
PMC6588407
AbstractArticlePDF–3.3M
16.
Adipocytes: A Novel Target for IL-15/IL-15Rα Cancer Gene Therapy
Run Xiao, Anthony G. Mansour, Wei Huang, Logan A. Chrislip, Ryan K. Wilkins, Nicholas J. Queen, Youssef Youssef, Hsiaoyin C. Mao, Michael A. Caligiuri, Lei Cao
Mol Ther. 2019 May 8; 27(5): 922–932. Published online 2019 Feb 16. doi: 10.1016/j.ymthe.2019.02.011
PMCID:
PMC6520519
AbstractArticlePDF–1.6M
17.
Interleukin-27 promotes CD8+ T cell reconstitution following antibody-mediated lymphoablation
Katayoun Ayasoufi, Daniel B. Zwick, Ran Fan, Suheyla Hasgur, Michael Nicosia, Victoria Gorbacheva, Karen S. Keslar, Booki Min, Robert L. Fairchild, Anna Valujskikh
JCI Insight. 2019 Apr 4; 4(7): e125489. Published online 2019 Apr 4. doi: 10.1172/jci.insight.125489
PMCID:
PMC6483639
AbstractArticlePDF–1.1M
18.
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells
Charlène Niogret, S. M. Shahjahan Miah, Giorgia Rota, Nicolas P. Fonta, Haiping Wang, Werner Held, Walter Birchmeier, Veronica Sexl, Wentian Yang, Eric Vivier, Ping-Chih Ho, Laurent Brossay, Greta Guarda
Nat Commun. 2019; 10: 1444. Published online 2019 Mar 29. doi: 10.1038/s41467-019-09431-3
PMCID:
PMC6441079
AbstractArticlePDF–1.6M
19.
IL-15 is a component of the inflammatory milieu in the tumor microenvironment promoting antitumor responses
Rosa M. Santana Carrero, Figen Beceren-Braun, Sarai C. Rivas, Shweta M. Hegde, Achintyan Gangadharan, Devin Plote, Gabriel Pham, Scott M. Anthony, Kimberly S. Schluns
Proc Natl Acad Sci U S A. 2019 Jan 8; 116(2): 599–608. Published online 2018 Dec 26. doi: 10.1073/pnas.1814642116
PMCID:
PMC6329954
AbstractArticlePDF–1.2M
20.
Mitochondrial ultrastructural adaptations in fast muscles of mice lacking IL15RA
Emanuele Loro, Sara Bisetto, Tejvir S. Khurana
J Cell Sci. 2018 Nov 1; 131(21): jcs218313. Published online 2018 Nov 2. doi: 10.1242/jcs.218313
PMCID:
PMC6240298
AbstractArticle

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