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Select item 101078791.

T cell autoimmunity and immune regulation to desmoglein 3, a pemphigus autoantigen

Hayato Takahashi, Hisato Iriki, Yasuhiko Asahina

J Dermatol. 2023 Feb; 50(2): 112–123. Published online 2022 Dec 20. doi: 10.1111/1346-8138.16663

PMCID:: PMC10107879

Abstract Article PDF–3.4M

Select item 88033372.

Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor

Lisa M. Godsel, Quinn R. Roth-Carter, Jennifer L. Koetsier, Lam C. Tsoi, Amber L. Huffine, Joshua A. Broussard, Gillian N. Fitz, Sarah M. Lloyd, Junghun Kweon, Hope E. Burks, Marihan Hegazy, Saki Amagai, Paul W. Harms, Xianying Xing, Joseph Kirma, Jodi L. Johnson, Gloria Urciuoli, Lynn T. Doglio, William R. Swindell, Rajeshwar Awatramani, Eli Sprecher, Xiaomin Bao, Eran Cohen-Barak, Caterina Missero, Johann E. Gudjonsson, Kathleen J. Green

J Clin Invest. 2022 Feb 1; 132(3): e144363. Published online 2022 Feb 1. doi: 10.1172/JCI144363

PMCID:: PMC8803337

Abstract Article PDF–3.6M

Select item 79387703.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 76559864.

Dsg2 Upregulation as a Rescue Mechanism in Pemphigus

Anna M. Sigmund, Letyfee S. Steinert, Desalegn T. Egu, Franziska C. Bayerbach, Jens Waschke, Franziska Vielmuth

Front Immunol. 2020; 11: 581370. Published online 2020 Oct 28. doi: 10.3389/fimmu.2020.581370

PMCID:: PMC7655986

Abstract Article PDF–2.4M

Select item 67765515.

The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53

Ambreen Rehman, Yang Cai, Christian Hünefeld, Hana Jedličková, Yunying Huang, Muy Teck Teh, Usama Sharif Ahmad, Jutamas Uttagomol, Ying Wang, Angray Kang, Gary Warnes, Catherine Harwood, Daniele Bergamaschi, Eric Kenneth Parkinson, Martin Röcken, Hong Wan

Cell Death Dis. 2019 Oct; 10(10): 750. Published online 2019 Oct 3. doi: 10.1038/s41419-019-1988-0

PMCID:: PMC6776551

Abstract Article PDF–6.1M

Select item 64414966.

Epidermal development requires ninein for spindle orientation and cortical microtubule organization

Nicolas Lecland, Chiung-Yueh Hsu, Cécile Chemin, Andreas Merdes, Christiane Bierkamp

Life Sci Alliance. 2019 Apr; 2(2): e201900373. Published online 2019 Mar 28. doi: 10.26508/lsa.201900373

PMCID:: PMC6441496

Abstract Article PDF–4.1M

Select item 63667177.

RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis

Yeon Ja Choi, Christine Laclef, Ning Yang, Abraham Andreu-Cervera, Joshua Lewis, Xuming Mao, Li Li, Elizabeth R. Snedecor, Ken-Ichi Takemaru, Chuan Qin, Sylvie Schneider-Maunoury, Kenneth R. Shroyer, Yusuf A. Hannun, Peter J. Koch, Richard A. Clark, Aimee S. Payne, Andrew P. Kowalczyk, Jiang Chen

PLoS Genet. 2019 Jan; 15(1): e1007914. Published online 2019 Jan 28. doi: 10.1371/journal.pgen.1007914

PMCID:: PMC6366717

Abstract Article PDF–4.7M

Select item 61529198.

Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion

Jingyuan Li, Yuan Yuan, Jinzhi He, Jifan Feng, Xia Han, Junjun Jing, Thach-Vu Ho, Jian Xu, Yang Chai

Dev Biol. Author manuscript; available in PMC 2019 Sep 1.

Published in final edited form as: Dev Biol. 2018 Sep 1; 441(1): 191–203. Published online 2018 Jul 5. doi: 10.1016/j.ydbio.2018.07.003

PMCID:: PMC6152919

Abstract Article PDF–3.8M

Select item 49220169.

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes

Frauke Völlner, Jawahir Ali, Nina Kurrle, Yvonne Exner, Rüdiger Eming, Michael Hertl, Antje Banning, Ritva Tikkanen

Sci Rep. 2016; 6: 28820. Published online 2016 Jun 27. doi: 10.1038/srep28820

PMCID:: PMC4922016

Abstract Article PDF–2.1M

Select item 443040310.

Mucosal pemphigus vulgaris anti-Dsg3 IgG are pathogenic to the oral mucosa of humanized Dsg3 mice

Donna A. Culton, Suzanne K. McCray, Moonhee Park, James C. Roberts, Jr., Ning Li, Daniel C. Zedek, Grant J. Anhalt, Dale Cowley, Zhi Liu, Luis A. Diaz

J Invest Dermatol. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: J Invest Dermatol. 2015 Jun; 135(6): 1590–1597. Published online 2015 Feb 19. doi: 10.1038/jid.2015.54

PMCID:: PMC4430403

Abstract Article PDF–1022K

Select item 434847411.

A Spontaneous Deletion within the Desmoglein 3 Extracellular Domain of Mice Results in Hypomorphic Protein Expression, Immunodeficiency, and a Wasting Disease Phenotype

Evgueni I. Kountikov, Jonathan C. Poe, Nancie J. Maclver, Jeffrey C. Rathmell, Thomas F. Tedder

Am J Pathol. 2015 Mar; 185(3): 617–630. doi: 10.1016/j.ajpath.2014.10.025

PMCID:: PMC4348474

Abstract Article PDF–4.9M

Select item 431955912.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 405914613.

Desmoglein 2 Compensates for Desmoglein 3 but Does Not Control Cell Adhesion via Regulation of p38 Mitogen-activated Protein Kinase in Keratinocytes

Eva Hartlieb, Vera Rötzer, Mariya Radeva, Volker Spindler, Jens Waschke

J Biol Chem. 2014 Jun 13; 289(24): 17043–17053. Published online 2014 Apr 29. doi: 10.1074/jbc.M113.489336

PMCID:: PMC4059146

Abstract Article PDF–2.5M

Select item 354286314.

p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome

Giustina Ferone, Maria Rosaria Mollo, Helen A. Thomason, Dario Antonini, Huiqing Zhou, Raffaele Ambrosio, Laura De Rosa, Domenico Salvatore, Spiro Getsios, Hans van Bokhoven, Jill Dixon, Caterina Missero

Hum Mol Genet. 2013 Feb 1; 22(3): 531–543. Published online 2012 Oct 29. doi: 10.1093/hmg/dds464

PMCID:: PMC3542863

Abstract Article PDF–571K

Select item 350371615.

Unimpaired Skin Carcinogenesis in Desmoglein 3 Knockout Mice

Sylvain Baron, Anabel Hoang, Hannes Vogel, Laura D. Attardi

PLoS One. 2012; 7(11): e50024. Published online 2012 Nov 21. doi: 10.1371/journal.pone.0050024

PMCID:: PMC3503716

Abstract Article PDF–4.3M

Select item 325836116.

An adult passive transfer mouse model to study desmoglein 3 signaling in pemphigus vulgaris

Katja Schulze, Arnaud Galichet, Beyza S. Sayar, Anthea Scothern, Denise Howald, Hillard Zymann, Myriam Siffert, Denise Zenhäusern, Reinhard Bolli, Peter J. Koch, David Garrod, Maja M. Suter, Eliane J. Müller

J Invest Dermatol. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: J Invest Dermatol. 2012 Feb; 132(2): 346–355. Published online 2011 Sep 29. doi: 10.1038/jid.2011.299

PMCID:: PMC3258361

Abstract Article PDF–2.0M

Select item 318138117.

The Extent of Desmoglein 3 Depletion in Pemphigus Vulgaris Is Dependent on Ca²⁺-Induced Differentiation: A Role in Suprabasal Epidermal Skin Splitting?

Volker Spindler, Alexander Endlich, Eva Hartlieb, Franziska Vielmuth, Enno Schmidt, Jens Waschke

Am J Pathol. 2011 Oct; 179(4): 1905–1916. doi: 10.1016/j.ajpath.2011.06.043

PMCID:: PMC3181381

Abstract Article PDF–2.8M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316396319.

Desmoglein 3–specific CD4⁺ T cells induce pemphigus vulgaris and interface dermatitis in mice

Hayato Takahashi, Michiyoshi Kouno, Keisuke Nagao, Naoko Wada, Tsuyoshi Hata, Shuhei Nishimoto, Yoichiro Iwakura, Akihiko Yoshimura, Taketo Yamada, Masataka Kuwana, Hideki Fujii, Shigeo Koyasu, Masayuki Amagai

J Clin Invest. 2011 Sep 1; 121(9): 3677–3688. Published online 2011 Aug 8. doi: 10.1172/JCI57379

PMCID:: PMC3163963

Abstract Article PDF–2.0M

Select item 316057720.

Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis

Kaelyn D. Sumigray, Hsin Chen, Terry Lechler

J Cell Biol. 2011 Aug 22; 194(4): 631–642. doi: 10.1083/jcb.201104009

PMCID:: PMC3160577

Abstract Article PDF–3.4M

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