PMC Links for GEO Profiles (Select 74513109) - PMC

Select item 69165081.

The solute carriers ZIP8 and ZIP14 regulate manganese accumulation in brain microvascular endothelial cells and control brain manganese levels

Brittany L. Steimle, Frances M. Smith, Daniel J. Kosman

J Biol Chem. 2019 Dec 13; 294(50): 19197–19208. Published online 2019 Nov 7. doi: 10.1074/jbc.RA119.009371

PMCID:: PMC6916508

Abstract Article PDF–1.2M

Select item 65565832.

The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis

Ivo Florin Scheiber, Yuze Wu, Shannon Elizabeth Morgan, Ningning Zhao

J Biol Chem. 2019 Jun 7; 294(23): 9147–9160. Published online 2019 Apr 26. doi: 10.1074/jbc.RA119.008762

PMCID:: PMC6556583

Abstract Article PDF–2.7M

Select item 59036753.

Conditional mouse models support the role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in bone homeostasis

Gretl Hendrickx, Vere M. Borra, Ellen Steenackers, Timur A. Yorgan, Christophe Hermans, Eveline Boudin, Jérôme J. Waterval, Ineke D. C. Jansen, Tolunay Beker Aydemir, Niels Kamerling, Geert J. Behets, Christine Plumeyer, Patrick C. D’Haese, Björn Busse, Vincent Everts, Martin Lammens, Geert Mortier, Robert J. Cousins, Thorsten Schinke, Robert J. Stokroos, Johannes J. Manni, Wim Van Hul

PLoS Genet. 2018 Apr; 14(4): e1007321. Published online 2018 Apr 5. doi: 10.1371/journal.pgen.1007321

PMCID:: PMC5903675

Abstract Article PDF–19M

Select item 54819394.

Metal Transporter Zip14 (Slc39a14) Deletion in Mice Increases Manganese Deposition and Produces Neurotoxic Signatures and Diminished Motor Activity

Tolunay Beker Aydemir, Min-Hyun Kim, Jinhee Kim, Luis M. Colon-Perez, Guita Banan, Thomas H. Mareci, Marcelo Febo, Robert J. Cousins

J Neurosci. 2017 Jun 21; 37(25): 5996–6006. doi: 10.1523/JNEUROSCI.0285-17.2017

PMCID:: PMC5481939

Abstract Article PDF–2.4M

Select item 51049205.

Hepatic ZIP14-mediated Zinc Transport Contributes to Endosomal Insulin Receptor Trafficking and Glucose Metabolism

Tolunay Beker Aydemir, Catalina Troche, Min-Hyun Kim, Robert J. Cousins

J Biol Chem. 2016 Nov 11; 291(46): 23939–23951. Published online 2016 Oct 4. doi: 10.1074/jbc.M116.748632

PMCID:: PMC5104920

Abstract Article PDF–2.9M

Select item 48949806.

Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism–dystonia

Karin Tuschl, Esther Meyer, Leonardo E. Valdivia, Ningning Zhao, Chris Dadswell, Alaa Abdul-Sada, Christina Y. Hung, Michael A. Simpson, W. K. Chong, Thomas S. Jacques, Randy L. Woltjer, Simon Eaton, Allison Gregory, Lynn Sanford, Eleanna Kara, Henry Houlden, Stephan M. Cuno, Holger Prokisch, Lorella Valletta, Valeria Tiranti, Rasha Younis, Eamonn R. Maher, John Spencer, Ania Straatman-Iwanowska, Paul Gissen, Laila A. M. Selim, Guillem Pintos-Morell, Wifredo Coroleu-Lletget, Shekeeb S. Mohammad, Sangeetha Yoganathan, Russell C. Dale, Maya Thomas, Jason Rihel, Olaf A. Bodamer, Caroline A. Enns, Susan J. Hayflick, Peter T. Clayton, Philippa B. Mills, Manju A. Kurian, Stephen W. Wilson

Nat Commun. 2016; 7: 11601. Published online 2016 May 27. doi: 10.1038/ncomms11601

PMCID:: PMC4894980

Abstract Article PDF–3.7M

Select item 47832547.

Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease

Alexander R. Bogdan, Masaki Miyazawa, Kazunori Hashimoto, Yoshiaki Tsuji

Trends Biochem Sci. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Trends Biochem Sci. 2016 Mar; 41(3): 274–286. Published online 2015 Dec 23. doi: 10.1016/j.tibs.2015.11.012

PMCID:: PMC4783254

Abstract Article PDF–1.6M

Select item 32205518.

Biochemical Characterization of Human ZIP13 Protein: A HOMO-DIMERIZED ZINC TRANSPORTER INVOLVED IN THE SPONDYLOCHEIRO DYSPLASTIC EHLERS-DANLOS SYNDROME

Bum-Ho Bin, Toshiyuki Fukada, Toshiaki Hosaka, Satoru Yamasaki, Wakana Ohashi, Shintaro Hojyo, Tomohiro Miyai, Keigo Nishida, Shigeyuki Yokoyama, Toshio Hirano

J Biol Chem. 2011 Nov 18; 286(46): 40255–40265. Published online 2011 Sep 14. doi: 10.1074/jbc.M111.256784

PMCID:: PMC3220551

Abstract Article PDF–2.7M

Select item 31915639.

Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron

Jorge J. Pinilla-Tenas, Brian K. Sparkman, Ali Shawki, Anthony C. Illing, Colin J. Mitchell, Ningning Zhao, Juan P. Liuzzi, Robert J. Cousins, Mitchell D. Knutson, Bryan Mackenzie

Am J Physiol Cell Physiol. 2011 Oct; 301(4): C862–C871. Published online 2011 Jun 8. doi: 10.1152/ajpcell.00479.2010