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Select item 115235651.

Specific blockade CD73 alters the ‘exhausted’ phenotype of T cells in head and neck squamous cell carcinoma

Wei-Wei Deng, Yi-Cun Li, Si-Rui Ma, Liang Mao, Guang-Tao Yu, Lin-Lin Bu, Ashok B. Kulkarni, Wen-Feng Zhang, Zhi-Jun Sun

Int J Cancer. Author manuscript; available in PMC 2024 Oct 30.

Published in final edited form as: Int J Cancer. 2018 Sep 15; 143(6): 1494–1504. doi: 10.1002/ijc.31534

PMCID:: PMC11523565

Abstract Article PDF–1.5M

Select item 115139812.

CD73 promotes non–small cell lung cancer metastasis by regulating Axl signaling independent of GAS6

Jianjie Zhu, Wenwen Du, Yuanyuan Zeng, Ting Liu, Jianjun Li, Anqi Wang, Yue Li, Weijie Zhang, Jian-an Huang, Zeyi Liu

Proc Natl Acad Sci U S A. 2024 Oct 22; 121(43): e2404709121. Published online 2024 Oct 18. doi: 10.1073/pnas.2404709121

PMCID:: PMC11513981

Abstract Article PDF–13M

Select item 112929233.

Regulation of CD73 on NAD metabolism: Unravelling the interplay between tumour immunity and tumour metabolism

Jianhao Zhan, Le Huang, Liyan Niu, Wenhui Lu, Chengpeng Sun, Shanshan Liu, Zijun Ding, Enliang Li

Cell Commun Signal. 2024; 22: 387. Published online 2024 Aug 1. doi: 10.1186/s12964-024-01755-y

PMCID:: PMC11292923

Abstract Article PDF–2.2M

Select item 112310434.

The immunomodulatory ballet of tumour‐derived extracellular vesicles and neutrophils orchestrating the dynamic CD73/PD‐L1 pathway in cancer

Dominique S. Rubenich, Jordana L. Domagalski, Gabriela F. S. Gentil, Jonas Eichberger, Mathias Fiedler, Florian Weber, Marianne Federlin, Hendrik Poeck, Torsten E. Reichert, Tobias Ettl, Richard J. Bauer, Elizandra Braganhol, Daniela Schulz

J Extracell Vesicles. 2024 Jul; 13(7): e12480. Published online 2024 Jul 8. doi: 10.1002/jev2.12480

PMCID:: PMC11231043

Abstract Article PDF–3.4M

Select item 111893795.

ENTPD1 (CD39) and NT5E (CD73) expression in human glioblastoma: an in silico analysis

Elizandra Braganhol, Guilherme Pamplona Bueno de Andrade, Guilherme Tomasi Santos, Marco Antônio Stefani

Purinergic Signal. 2024 Jun; 20(3): 285–289. Published online 2023 Jul 4. doi: 10.1007/s11302-023-09951-0

PMCID:: PMC11189379

Abstract Article PDF–423K

Select item 111599016.

RNAi‐mediated CD73 suppression induces apoptosis and cell‐cycle arrest in human breast cancer cells

Xiuling Zhi, Yingjian Wang, Xuerui Zhou, Jerry Yu, Rongrong Jian, Shaoxian Tang, Lianhua Yin, Ping Zhou

Cancer Sci. 2010 Dec; 101(12): 2561–2569. Published online 2010 Sep 28. doi: 10.1111/j.1349-7006.2010.01733.x

PMCID:: PMC11159901

Abstract Article PDF–1.2M

Select item 110287877.

Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity

Sebastian F. M. Häusler, Itsaso Montalbán del Barrio, Jenny Strohschein, P. Anoop Chandran, Jörg B. Engel, Arnd Hönig, Monika Ossadnik, Evi Horn, Birgitt Fischer, Mathias Krockenberger, Stefan Heuer, Ahmed Adel Seida, Markus Junker, Hermann Kneitz, Doris Kloor, Karl-Norbert Klotz, Johannes Dietl, Jörg Wischhusen

Cancer Immunol Immunother. 2011 Oct; 60(10): 1405–1418. Published online 2011 Jun 3. doi: 10.1007/s00262-011-1040-4

PMCID:: PMC11028787

Abstract Article PDF–2.1M

Select item 109924438.

Functional expression of CD73 on human natural killer cells

Andrea M. Chambers, Jiao Wang, Tram N. Dao, Kyle B. Lupo, Paige Veenhuis, Mitchell G. Ayers, Veronika Slivova, Aaron A. Cohen-Gadol, Sandro Matosevic

Cancer Immunol Immunother. 2022 Dec; 71(12): 3043–3056. Published online 2022 May 25. doi: 10.1007/s00262-022-03219-z

PMCID:: PMC10992443

Abstract Article PDF–2.2M

Select item 108381539.

The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency

Hannah S. Sperber, Kyle A. Raymond, Mohamed S. Bouzidi, Tongcui Ma, Silvana Valdebenito, Eliseo A. Eugenin, Nadia R. Roan, Steven G. Deeks, Sandra Winning, Joachim Fandrey, Roland Schwarzer, Satish K. Pillai

Cell Rep. Author manuscript; available in PMC 2024 Feb 3.

Published in final edited form as: Cell Rep. 2023 Nov 28; 42(11): 113285. Published online 2023 Oct 31. doi: 10.1016/j.celrep.2023.113285

PMCID:: PMC10838153

Abstract Article PDF–2.9M

Select item 1082813210.

Human plasmacytoid dendritic cells express the functional purinergic halo (CD39/CD73)

S. A. Sosa-Luis, W. J. Ríos-Ríos, A. Almaraz-Arreortua, M. A. Romero-Tlalolini, S. R. Aguilar-Ruiz, R. Valle-Ríos, C. Sánchez-Torres, H. Torres-Aguilar

Purinergic Signal. 2024 Feb; 20(1): 73–82. Published online 2023 Apr 14. doi: 10.1007/s11302-023-09940-3

PMCID:: PMC10828132

Abstract Article PDF–1.0M

Select item 1082324711.

CD73 contributes to the pathogenesis of fusion-negative rhabdomyosarcoma through the purinergic signaling pathway

Karla Cano Hernandez, Akansha M. Shah, Victor A. Lopez, Vincent S. Tagliabracci, Kenian Chen, Lin Xu, Rhonda Bassel-Duby, Eric N. Olson, Ning Liu

Proc Natl Acad Sci U S A. 2024 Jan 23; 121(4): e2315925121. Published online 2024 Jan 16. doi: 10.1073/pnas.2315925121

PMCID:: PMC10823247

Abstract Article PDF–4.9M

Select item 1081316112.

Altered CD39 and CD73 Expression in Rheumatoid Arthritis: Implications for Disease Activity and Treatment Response

María Angels Ortiz, Cesar Diaz-Torné, Juan Jose De Agustin, Paula Estrada, Delia Reina, María Victoria Hernandez, Hye Sang, Carlos Zamora, Elisabet Cantó, Hector Corominas, Silvia Vidal

Biomolecules. 2024 Jan; 14(1): 1. Published online 2023 Dec 19. doi: 10.3390/biom14010001

PMCID:: PMC10813161

Abstract Article PDF–3.1M

Select item 1079990313.

Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly

Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun

Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0

PMCID:: PMC10799903

Abstract Article PDF–25M

Select item 1058435114.

CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells

Remi Samain, Oscar Maiques, Joanne Monger, Hoyin Lam, Juliana Candido, Samantha George, Nicola Ferrari, Leonie KohIhammer, Sophia Lunetto, Adrian Varela, Jose L. Orgaz, Felip Vilardell, Jorge Juan Olsina, Xavier Matias-Guiu, Debashis Sarker, Adrian Biddle, Frances R. Balkwill, Jim Eyles, Robert W. Wilkinson, Hemant M. Kocher, Fernando Calvo, Claire M. Wells, Victoria Sanz-Moreno

Sci Adv. 2023 Oct 20; 9(42): eadi0244. Published online 2023 Oct 18. doi: 10.1126/sciadv.adi0244

PMCID:: PMC10584351

Abstract Article PDF–2.8M

Select item 1046339815.

5ʹ-Ectonucleotidase CD73/NT5E supports EGFR-mediated invasion of HPV-negative head and neck carcinoma cells

Enxian Shi, Zhengquan Wu, Birnur Sinem Karaoglan, Sabina Schwenk-Zieger, Gisela Kranz, Nilofer Abdul Razak, Christoph A. Reichel, Martin Canis, Philipp Baumeister, Reinhard Zeidler, Olivier Gires

J Biomed Sci. 2023; 30: 72. Published online 2023 Aug 24. doi: 10.1186/s12929-023-00968-6

PMCID:: PMC10463398

Abstract Article PDF–6.2M

Select item 1038075916.

The Clinical Significance of CD73 in Cancer

Niklas Bach, Riekje Winzer, Eva Tolosa, Walter Fiedler, Franziska Brauneck

Int J Mol Sci. 2023 Jul; 24(14): 11759. Published online 2023 Jul 21. doi: 10.3390/ijms241411759

PMCID:: PMC10380759

Abstract Article PDF–1.4M

Select item 1025949017.

The CD73 immune checkpoint promotes tumor cell metabolic fitness

David Allard, Isabelle Cousineau, Eric H Ma, Bertrand Allard, Yacine Bareche, Hubert Fleury, John Stagg

eLife. 2023; 12: e84508. Published online 2023 Jun 1. doi: 10.7554/eLife.84508

PMCID:: PMC10259490

Abstract Article PDF–1.6M

Select item 1023742218.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1007181919.

CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer

Erika Y. Faraoni, Kanchan Singh, Vidhi Chandra, Olivereen Le Roux, Yulin Dai, Ismet Sahin, Baylee J. O'Brien, Lincoln N. Strickland, Le Li, Emily Vucic, Amanda N. Warner, Melissa Pruski, Trent Clark, George Van Buren, Nirav C. Thosani, John S. Bynon, Curtis J. Wray, Dafna Bar-Sagi, Kyle L. Poulsen, Lana A. Vornik, Michelle I. Savage, Shizuko Sei, Altaf Mohammed, Zhongming Zhao, Powel H. Brown, Tingting Mills, Holger K. Eltzschig, Florencia McAllister, Jennifer M. Bailey-Lundberg

Cancer Res. 2023 Apr 4; 83(7): 1111–1127. Published online 2023 Jan 31. doi: 10.1158/0008-5472.CAN-22-2553

PMCID:: PMC10071819

Abstract Article PDF–23M

Select item 999952520.

Integrative analyses identify CD73 as a prognostic biomarker and immunotherapeutic target in intrahepatic cholangiocarcinoma

Bao-Ye Sun, Zhang-Fu Yang, Zhu-Tao Wang, Gao Liu, Cheng Zhou, Jian Zhou, Jia Fan, Wei Gan, Yong Yi, Shuang-Jian Qiu

World J Surg Oncol. 2023; 21: 90. Published online 2023 Mar 10. doi: 10.1186/s12957-023-02970-6

PMCID:: PMC9999525

Abstract Article PDF–13M

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