PMC Links for GEO Profiles (Select 72990795) - PMC

Justin W. Magrath, Shruthi Sanjitha Sampath, Dane A. Flinchum, Alifiani B. Hartono, Ilon N. Goldberg, Julia R. Boehling, Suzana D. Savkovic, Sean B. Lee

Cancer Res. 2024 May 2; 84(9): 1426–1442. Published online 2024 Apr 8. doi: 10.1158/0008-5472.CAN-23-3334

PMCID:: PMC11063761

Abstract Article PDF–24M

Select item 106995084.

Cyclin D-CDK4 Disulfide Bond Attenuates Pulmonary Vascular Cell Proliferation

Hannah Knight, Giancarlo Abis, Manpreet Kaur, Hannah L.H. Green, Susanne Krasemann, Kristin Hartmann, Steven Lynham, James Clark, Lan Zhao, Clemens Ruppert, Astrid Weiss, Ralph T. Schermuly, Philip Eaton, Olena Rudyk

Circ Res. 2023 Dec 8; 133(12): 966–988. Published online 2023 Nov 13. doi: 10.1161/CIRCRESAHA.122.321836

PMCID:: PMC10699508

Abstract Article PDF–11M

Select item 105759375.

DNA damage induced by CDK4 and CDK6 blockade triggers anti-tumor immune responses through cGAS-STING pathway

Huimin Fan, Wancheng Liu, Yanqiong Zeng, Ying Zhou, Meiling Gao, Liping Yang, Hao Liu, Yueyue Shi, Lili Li, Jiayuan Ma, Jiayin Ruan, Ruyun Cao, Xiaoxia Jin, Jian Chen, Genhong Cheng, Heng Yang

Commun Biol. 2023; 6: 1041. Published online 2023 Oct 13. doi: 10.1038/s42003-023-05412-x

PMCID:: PMC10575937

Abstract Article PDF–4.6M

Select item 104879946.

FOXM1, MEK, and CDK4/6: New Targets for Malignant Peripheral Nerve Sheath Tumor Therapy

Ellen Voigt, Dawn E. Quelle

Int J Mol Sci. 2023 Sep; 24(17): 13596. Published online 2023 Sep 2. doi: 10.3390/ijms241713596

PMCID:: PMC10487994

Abstract Article PDF–1.4M

Select item 102374227.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101059588.

Mitochondrial creatine kinase 1 regulates the cell cycle in non-small cell lung cancer via activation of cyclin-dependent kinase 4

Mengjie Yang, Xuecen Wang, Zhihua Ye, Tingyu Liu, Yuan Meng, Youfa Duan, Xuexia Yuan, Xin Yue, Wenbin Deng, Ran-yi Liu

Respir Res. 2023; 24: 111. Published online 2023 Apr 15. doi: 10.1186/s12931-023-02417-2

PMCID:: PMC10105958

Abstract Article PDF–5.6M

Select item 100809089.

The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia

Sadek Amhaz, Batiste Boëda, Mouna Chouchène, Sabrina Colasse, Florent Dingli, Damarys Loew, Julien Henri, Céline Prunier, Laurence Levy

BMC Biol. 2023; 21: 73. Published online 2023 Apr 7. doi: 10.1186/s12915-023-01576-4

PMCID:: PMC10080908

Abstract Article PDF–3.2M

Select item 995018310.

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini

Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3

PMCID:: PMC9950183

Abstract Article PDF–2.4M

Select item 991745111.

Insights into the Peritumoural Brain Zone of Glioblastoma: CDK4 and EXT2 May Be Potential Drivers of Malignancy

Martina Giambra, Andrea Di Cristofori, Donatella Conconi, Matilde Marzorati, Serena Redaelli, Melissa Zambuto, Alessandra Rocca, Louis Roumy, Giorgio Carrabba, Marialuisa Lavitrano, Gaia Roversi, Carlo Giussani, Angela Bentivegna

Int J Mol Sci. 2023 Feb; 24(3): 2835. Published online 2023 Feb 2. doi: 10.3390/ijms24032835

PMCID:: PMC9917451

Abstract Article PDF–6.8M

Select item 991654712.

Deciphering the Immunomodulatory Role of Cyclin-Dependent Kinase 4/6 Inhibitors in the Tumor Microenvironment

Pratibha Pandey, Fahad Khan, Tarun Kumar Upadhyay, Amit Baran Sharangi

Int J Mol Sci. 2023 Feb; 24(3): 2236. Published online 2023 Jan 23. doi: 10.3390/ijms24032236

PMCID:: PMC9916547

Abstract Article PDF–858K

Select item 990929713.

Hypoxia-induced RBBP7 promotes esophagus cancer progression by inducing CDK4 expression: RBBP7 promotes esophagus cancer progression

Renfeng Wang, Zhiliang Huang, Zhenyang Lin, Borong Chen, Xuguang Pang, Chaoxiang Du, Hong Fan

Acta Biochim Biophys Sin (Shanghai) 2022 Feb; 54(2): 179–186. Published online 2022 Jan 19. doi: 10.3724/abbs.2021027

PMCID:: PMC9909297

Abstract Article PDF–4.8M

Select item 983441914.

MicroRNA-1205 Suppresses Hepatocellular Carcinoma Cell Proliferation via a CSNK2B/CDK4 Axis

Xiang Li, Shujie Xie, Qin Xia, Jia Yan, Shuhuai Chen, Jia Shen

Technol Cancer Res Treat. 2023; 22: 15330338221150544. Published online 2023 Jan 9. doi: 10.1177/15330338221150544

PMCID:: PMC9834419

Abstract Article PDF–4.1M

Select item 976969815.

A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor

Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth

Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.

Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841

PMCID:: PMC9769698

Abstract Article PDF–2.7M

Select item 972945616.

MDM2 Gene Amplification and Expression of MDM2 and CDK4 are Rare in Ossifying Fibroma of Craniofacial Bones

Dorukhan H. Bahceci, Richard C. K. Jordan, Andrew E. Horvai

Head Neck Pathol. 2022 Dec; 16(4): 991–997. Published online 2022 May 11. doi: 10.1007/s12105-022-01454-5

PMCID:: PMC9729456

Abstract Article PDF–1.4M

Select item 959464117.

S-glutathionylation of Hsp90 enhances its degradation and correlates with favorable prognosis of breast cancer

Yu-Yin Shih, Hsien-Ya Lin, Hau-Ming Jan, Yu-Ju Chen, Lih-Lih Ong, Alice Lin-Tsing Yu, Chun-Hung Lin

Redox Biol. 2022 Nov; 57: 102501. Published online 2022 Oct 15. doi: 10.1016/j.redox.2022.102501

PMCID:: PMC9594641

Abstract Article PDF–5.4M

Select item 948193318.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 930064919.

Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroup

Angela Martinez-Monleon, Hanna Kryh Öberg, Jennie Gaarder, Ana P. Berbegall, Niloufar Javanmardi, Anna Djos, Marek Ussowicz, Sabine Taschner-Mandl, Inge M. Ambros, Ingrid Øra, Bengt Sandstedt, Klaus Beiske, Ruth Ladenstein, Rosa Noguera, Peter F. Ambros, Lena Gordon Murkes, Gustaf Ljungman, Per Kogner, Susanne Fransson, Tommy Martinsson

Sci Rep. 2022; 12: 12420. Published online 2022 Jul 20. doi: 10.1038/s41598-022-16455-1