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Select item 113009311.

Hepatic glucokinase regulatory protein and carbohydrate response element binding protein attenuation reduce de novo lipogenesis but do not mitigate intrahepatic triglyceride accumulation in Aldob deficiency

Amée M. Buziau, Maaike H. Oosterveer, Kristiaan Wouters, Trijnie Bos, Dean R. Tolan, Loranne Agius, Brian E. Ford, David Cassiman, Coen D.A. Stehouwer, Casper G. Schalkwijk, Martijn C.G.J. Brouwers

Mol Metab. 2024 Sep; 87: 101984. Published online 2024 Jul 6. doi: 10.1016/j.molmet.2024.101984

PMCID:: PMC11300931

Abstract Article PDF–882K

Select item 112396812.

Activation of AMPD2 drives metabolic dysregulation and liver disease in mice with hereditary fructose intolerance

Ana Andres-Hernando, David J. Orlicky, Masanari Kuwabara, Mehdi A. Fini, Dean R. Tolan, Richard J. Johnson, Miguel A. Lanaspa

Commun Biol. 2024; 7: 849. Published online 2024 Jul 11. doi: 10.1038/s42003-024-06539-1

PMCID:: PMC11239681

Abstract Article PDF–2.8M

Select item 109453493.

NPC1 is required for postnatal islet β cell differentiation by maintaining mitochondria turnover

Bei Liu, Duanyi Hua, Linyan Shen, Tingting Li, Zheying Tao, Chenyang Fu, Zhongzheng Tang, Jie Yang, Li Zhang, Aifang Nie, Yiran Jiang, Jiqiu Wang, Yang Li, Yanyun Gu, Guang Ning

Theranostics. 2024; 14(5): 2058–2074. Published online 2024 Feb 24. doi: 10.7150/thno.90946

PMCID:: PMC10945349

Abstract Article PDF–9.7M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 73606816.

Peroxisome-Deficiency and HIF-2α Signaling Are Negative Regulators of Ketohexokinase Expression

Tanja Eberhart, Miriam J. Schönenberger, Katharina M. Walter, Khanichi N. Charles, Phyllis L. Faust, Werner J. Kovacs

Front Cell Dev Biol. 2020; 8: 566. Published online 2020 Jul 8. doi: 10.3389/fcell.2020.00566

PMCID:: PMC7360681

Abstract Article PDF–5.6M

Select item 72350487.

TFEB regulates murine liver cell fate during development and regeneration

Nunzia Pastore, Tuong Huynh, Niculin J. Herz, Alessia Calcagni’, Tiemo J. Klisch, Lorenzo Brunetti, Kangho Ho Kim, Marco De Giorgi, Ayrea Hurley, Annamaria Carissimo, Margherita Mutarelli, Niya Aleksieva, Luca D’Orsi, William R. Lagor, David D. Moore, Carmine Settembre, Milton J. Finegold, Stuart J. Forbes, Andrea Ballabio

Nat Commun. 2020; 11: 2461. Published online 2020 May 18. doi: 10.1038/s41467-020-16300-x

PMCID:: PMC7235048

Abstract Article PDF–8.7M

Select item 59833428.

Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice

Miguel A. Lanaspa, Ana Andres-Hernando, David J. Orlicky, Christina Cicerchi, Cholsoon Jang, Nanxing Li, Tamara Milagres, Masanari Kuwabara, Michael F. Wempe, Joshua D. Rabinowitz, Richard J. Johnson, Dean R. Tolan

J Clin Invest. 2018 Jun 1; 128(6): 2226–2238. Published online 2018 Apr 23. doi: 10.1172/JCI94427

PMCID:: PMC5983342

Abstract Article PDF–8.7M

Select item 53376189.

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development

Vinay Bulusu, Nicole Prior, Marteinn T. Snaebjornsson, Andreas Kuehne, Katharina F. Sonnen, Jana Kress, Frank Stein, Carsten Schultz, Uwe Sauer, Alexander Aulehla

Dev Cell. 2017 Feb 27; 40(4): 331–341.e4. doi: 10.1016/j.devcel.2017.01.015

PMCID:: PMC5337618

Abstract Article

Select item 527862810.

Rewiring of embryonic glucose metabolism via suppression of PFK-1 and aldolase during mouse chorioallantoic branching

Hidenobu Miyazawa, Yoshifumi Yamaguchi, Yuki Sugiura, Kurara Honda, Koki Kondo, Fumio Matsuda, Takehiro Yamamoto, Makoto Suematsu, Masayuki Miura

Development. 2017 Jan 1; 144(1): 63–73. doi: 10.1242/dev.138545

PMCID:: PMC5278628

Abstract Article

Select item 494642711.

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series

Caitlyn E. Bowman, Liang Zhao, Thomas Hartung, Michael J. Wolfgang

Mol Cell Biol. 2016 Aug 1; 36(15): 2089–2104. Prepublished online 2016 May 23. Published online 2016 Jul 14. doi: 10.1128/MCB.00166-16

PMCID:: PMC4946427

Abstract Article PDF–3.4M

Select item 396495512.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 358127213.

Hepatocyte Nuclear Factor 4α Is Essential for Embryonic Development of the Mouse Colon

Wendy D. Garrison, Michele A. Battle, Chuhu Yang, Klaus H. Kaestner, Frances M. Sladek, Stephen A. Duncan

Gastroenterology. Author manuscript; available in PMC 2013 Feb 25.

Published in final edited form as: Gastroenterology. 2006 Apr; 130(4): 1207–1220. doi: 10.1053/j.gastro.2006.01.003

PMCID:: PMC3581272

Abstract Article PDF–7.8M

Select item 357241014.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253416.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 197613417.

An analysis of expression patterns of genes encoding proteins with catalytic activities

Murat Cankaya, Ana Martinez Hernandez, Mehmet Ciftci, Sukru Beydemir, Hasan Ozdemir, Harun Budak, Ilhami Gulcin, Veysel Comakli, Tufan Emircupani, Deniz Ekinci, Muslum Kuzu, Qiuhong Jiang, Gregor Eichele, Omer Irfan Kufrevioglu

BMC Genomics. 2007; 8: 232. Published online 2007 Jul 12. doi: 10.1186/1471-2164-8-232