U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 332

1.
Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation
Jian-Xin Lin, Meili Ge, Cheng-yu Liu, Ronald Holewinski, Thorkell Andresson, Zu-Xi Yu, Tesfay Gebregiorgis, Rosanne Spolski, Peng Li, Warren J. Leonard
Nat Commun. 2024; 15: 7372. Published online 2024 Aug 27. doi: 10.1038/s41467-024-50925-6
PMCID:
PMC11349758
AbstractArticlePDF–3.5M
2.
Interleukin 2 regulation following semi-allogeneic bone marrow transplantation in mice
Ali Abdul-Hai, Arie Ben-Yehuda, Haya Galsky, Shimon Slavin, Reuven Or
Cancer Immunol Immunother. 2006 Nov; 55(11): 1330–1336. Published online 2006 Feb 1. doi: 10.1007/s00262-006-0125-y
PMCID:
PMC11030658
AbstractArticlePDF–314K
3.
PD-1 Limits IL-2 Production and Thymic Regulatory T Cell Development
Breanna Caruso, Benjamin R. Weeder, Reid F. Thompson, Amy E. Moran
Immunohorizons. 2024 Mar 1; 8(3): 281–294. Published online 2024 Mar 29. doi: 10.4049/immunohorizons.2300079
PMCID:
PMC10985057
AbstractArticlePDF–2.1M
4.
Tumor-infiltrating mast cells stimulate ICOS+ regulatory T cells through an IL-33 and IL-2 axis to promote gastric cancer progression
Yipin Lv, Wenqing Tian, Yongsheng Teng, Pan Wang, Yongliang Zhao, Zhengyan Li, Shanhong Tang, Weisan Chen, Rui Xie, Muhan Lü, Yuan Zhuang
J Adv Res. 2024 Mar; 57: 149–162. Published online 2023 Apr 20. doi: 10.1016/j.jare.2023.04.013
PMCID:
PMC10918354
AbstractArticlePDF–5.9M
5.
Regulatory T cells use heparanase to access IL-2 bound to extracellular matrix in inflamed tissue
Hunter A. Martinez, Ievgen Koliesnik, Gernot Kaber, Jacqueline K. Reid, Nadine Nagy, Graham Barlow, Ben A. Falk, Carlos O. Medina, Aviv Hargil, Svenja Zihsler, Israel Vlodavsky, Jin-Ping Li, Magdiel Pérez-Cruz, Sai-Wen Tang, Everett H. Meyer, Lucile E. Wrenshall, James D. Lord, K. Christopher Garcia, Theo D. Palmer, Lawrence Steinman, Gerald T. Nepom, Thomas N. Wight, Paul L. Bollyky, Hedwich F. Kuipers
Nat Commun. 2024; 15: 1564. Published online 2024 Feb 20. doi: 10.1038/s41467-024-45012-9
PMCID:
PMC10879116
AbstractArticlePDF–3.7M
6.
Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells
Melanie R. Shapiro, Leeana D. Peters, Matthew E. Brown, Cecilia Cabello-Kindelan, Amanda L. Posgai, Allison L. Bayer, Todd M. Brusko
J Immunol. 2023 Oct 1; 211(7): 1108–1122. Published online 2023 Aug 18. doi: 10.4049/jimmunol.2200651
PMCID:
PMC10511790
AbstractArticlePDF–3.3M
7.
Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
Trang T. T. Nguyen, Wen Lu, Wandi S. Zhu, K. Mark Ansel, Hong-Erh Liang, Arthur Weiss
Proc Natl Acad Sci U S A. 2023 Jun 20; 120(25): e2300987120. Published online 2023 Jun 12. doi: 10.1073/pnas.2300987120
PMCID:
PMC10288620
AbstractArticlePDF–2.0M
8.
Optimal generation of hepatic tissue-resident memory CD4 T cells requires IL-1 and IL-2
Claire E. Depew, Jordan A. Rixon, Stephen J. McSorley
Proc Natl Acad Sci U S A. 2023 Apr 18; 120(16): e2214699120. Published online 2023 Apr 11. doi: 10.1073/pnas.2214699120
PMCID:
PMC10120061
AbstractArticlePDF–3.6M
9.
Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2
Oksana Tsyklauri, Tereza Chadimova, Veronika Niederlova, Jirina Kovarova, Juraj Michalik, Iva Malatova, Sarka Janusova, Olha Ivashchenko, Helene Rossez, Ales Drobek, Hana Vecerova, Virginie Galati, Marek Kovar, Ondrej Stepanek
eLife. 2023; 12: e79342. Published online 2023 Jan 27. doi: 10.7554/eLife.79342
PMCID:
PMC9977273
AbstractArticlePDF–3.2M
10.
Low-Dose IL-2 Attenuated Depression-like Behaviors and Pathological Changes through Restoring the Balances between IL-6 and TGF-β and between Th17 and Treg in a Chronic Stress-Induced Mouse Model of Depression
Chengyi Huang, Fucheng Zhang, Peng Li, Cai Song
Int J Mol Sci. 2022 Nov; 23(22): 13856. Published online 2022 Nov 10. doi: 10.3390/ijms232213856
PMCID:
PMC9699071
AbstractArticlePDF–3.1M
11.
Dopaminergic Signalling Enhances IL-2 Production and Strengthens Anti-Tumour Response Exerted by Cytotoxic T Lymphocytes in a Melanoma Mouse Model
Ornella Chovar-Vera, Ernesto López, Felipe Gálvez-Cancino, Carolina Prado, Dafne Franz, Diego A. Figueroa, Alexandra Espinoza, Claudio Figueroa, Alvaro Lladser, Rodrigo Pacheco
Cells. 2022 Nov; 11(22): 3536. Published online 2022 Nov 9. doi: 10.3390/cells11223536
PMCID:
PMC9688276
AbstractArticlePDF–1.7M
12.
Diversity-Oriented Synthesis of a Molecular Library of Immunomodulatory α-Galactosylceramides with Fluorous-Tag-Assisted Purification and Evaluation of Their Bioactivities in Regard to IL-2 Secretion
Yeng-Nan Chen, Jung-Tung Hung, Fan-Dan Jan, Yung-Yu Su, Jih-Ru Hwu, Alice L. Yu, Avijit K. Adak, Chun-Cheng Lin
Int J Mol Sci. 2022 Nov; 23(21): 13403. Published online 2022 Nov 2. doi: 10.3390/ijms232113403
PMCID:
PMC9659121
AbstractArticlePDF–4.1M
13.
IL-2 and IL-15 drive intrathymic development of distinct periphery-seeding CD4+Foxp3+ regulatory T lymphocytes
Cécile Apert, Ariel O. Galindo-Albarrán, Sarah Castan, Claire Detraves, Héloise Michaud, Nicola McJannett, Bart Haegeman, Simon Fillatreau, Bernard Malissen, Georg Holländer, Saulius Žuklys, Jérémy C. Santamaria, Olivier P. Joffre, Paola Romagnoli, Joost P. M. van Meerwijk
Front Immunol. 2022; 13: 965303. Published online 2022 Sep 8. doi: 10.3389/fimmu.2022.965303
PMCID:
PMC9495261
AbstractArticlePDF–6.3M
14.
The antitumor effect induced by an IL-2 ‘no-alpha’ mutein depends on changes in the CD8+ T lymphocyte/Treg cell balance
Tania Carmenate, Galia Montalvo, Sum Lai Lozada, Yaretnis Rodriguez, Yaquelin Ortiz, Claudia Díaz, Janet Avellanet, Juhee Kim, Charles D. Surh, Luis Graça, Kalet León
Front Immunol. 2022; 13: 974188. Published online 2022 Aug 17. doi: 10.3389/fimmu.2022.974188
PMCID:
PMC9428827
AbstractArticlePDF–1.2M
15.
Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits
Carly E. Whyte, Kailash Singh, Oliver T. Burton, Meryem Aloulou, Lubna Kouser, Rafael Valente Veiga, Amy Dashwood, Hanneke Okkenhaug, Samira Benadda, Alena Moudra, Orian Bricard, Stephanie Lienart, Pascal Bielefeld, Carlos P. Roca, Francisco José Naranjo-Galindo, Félix Lombard-Vadnais, Steffie Junius, David Bending, Masahiro Ono, Tino Hochepied, Timotheus Y.F. Halim, Susan Schlenner, Sylvie Lesage, James Dooley, Adrian Liston
J Exp Med. 2022 Jul 4; 219(7): e20212391. Published online 2022 Jun 14. doi: 10.1084/jem.20212391
Correction in:
J Exp Med. 2022 Aug 1; 219(8): jem.2021149805312022c.
PMCID:
PMC9202720
AbstractArticlePDF–9.2M
16.
Intrinsic IL-2 Production by Effector CD8 T Cells Affects IL-2 Signaling and Promotes Fate Decisions, Stemness, and Protection
Shannon M. Kahan, Rakesh K. Bakshi, Jennifer T. Ingram, R. Curtis Hendrickson, Elliot J. Lefkowitz, David K. Crossman, Laurie E. Harrington, Casey T. Weaver, Allan J. Zajac
Sci Immunol. Author manuscript; available in PMC 2023 Feb 11.
Published in final edited form as: Sci Immunol. 2022 Feb 11; 7(68): eabl6322. Published online 2022 Feb 11. doi: 10.1126/sciimmunol.abl6322
PMCID:
PMC8923238
AbstractArticlePDF–3.1M
17.
Selective delivery of low-affinity IL-2 to PD-1+ T cells rejuvenates antitumor immunity with reduced toxicity
Zhenhua Ren, Anli Zhang, Zhichen Sun, Yong Liang, Jianfeng Ye, Jian Qiao, Bo Li, Yang-Xin Fu
J Clin Invest. 2022 Feb 1; 132(3): e153604. Published online 2022 Feb 1. doi: 10.1172/JCI153604
PMCID:
PMC8803347
AbstractArticlePDF–4.6M
18.
Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
Francesco Marangoni, Ademi Zhakyp, Michela Corsini, Shannon N. Geels, Esteban Carrizosa, Martin Thelen, Vinidhra Mani, Jasper N. Prüßmann, Ross D. Warner, Aleksandra J. Ozga, Mauro Di Pilato, Shivashankar Othy, Thorsten R. Mempel
Cell. Author manuscript; available in PMC 2022 Jul 22.
Published in final edited form as: Cell. 2021 Jul 22; 184(15): 3998–4015.e19. Published online 2021 Jun 21. doi: 10.1016/j.cell.2021.05.027
PMCID:
PMC8664158
AbstractArticlePDF–2.6M
19.
The Blockade of Interleukin-2 During the Acute Phase of Trypanosoma cruzi Infection Reveals Its Dominant Regulatory Role
Jorge Nihei, Fabiola Cardillo, Jose Mengel
Front Cell Infect Microbiol. 2021; 11: 758273. Published online 2021 Nov 17. doi: 10.3389/fcimb.2021.758273
PMCID:
PMC8635756
AbstractArticlePDF–3.5M
20.
Enhanced IL-2 in early life limits the development of TFH and protective antiviral immunity
Chloe J. Pyle, Lucia Labeur-Iurman, Helen T. Groves, Franz Puttur, Clare M. Lloyd, John S. Tregoning, James A. Harker
J Exp Med. 2021 Dec 6; 218(12): e20201555. Published online 2021 Oct 19. doi: 10.1084/jem.20201555
PMCID:
PMC8529914
AbstractArticlePDF–6.3M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center