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Items: 1 to 20 of 26

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Fibulin-3 is necessary to prevent cardiac rupture following myocardial infarction
Lucy A. Murtha, Sean A. Hardy, Nishani S. Mabotuwana, Mark J. Bigland, Taleah Bailey, Kalyan Raguram, Saifei Liu, Doan T. Ngo, Aaron L. Sverdlov, Tamara Tomin, Ruth Birner-Gruenberger, Robert D. Hume, Siiri E. Iismaa, David T. Humphreys, Ralph Patrick, James J. H. Chong, Randall J. Lee, Richard P. Harvey, Robert M. Graham, Peter P. Rainer, Andrew J. Boyle
Sci Rep. 2023; 13: 14995. Published online 2023 Sep 11. doi: 10.1038/s41598-023-41894-9
PMCID:
PMC10495317
AbstractArticlePDF–3.2M
3.
Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration
Maura A Crowley, Donita L Garland, Holger Sellner, Angela Banks, Lin Fan, Tomas Rejtar, Natasha Buchanan, Omar Delgado, Yong Yao Xu, Sandra Jose, Christopher M Adams, Muneto Mogi, Karen Wang, Chad E Bigelow, Stephen Poor, Karen Anderson, Bruce D Jaffee, Ganesh Prasanna, Cynthia Grosskreutz, Rosario Fernandez-Godino, Eric A Pierce, Thaddeus P Dryja, Sha-Mei Liao
Hum Mol Genet. 2023 Jan 15; 32(2): 204–217. Published online 2022 Aug 9. doi: 10.1093/hmg/ddac187
PMCID:
PMC9840207
AbstractArticlePDF–1.8M
4.
Complement C5 is not critical for the formation of sub-RPE deposits in Efemp1 mutant mice
Donita L. Garland, Eric A. Pierce, Rosario Fernandez-Godino
Sci Rep. 2021; 11: 10416. Published online 2021 May 17. doi: 10.1038/s41598-021-89978-8
PMCID:
PMC8128922
AbstractArticlePDF–1.8M
5.
The Efemp1R345W Macular Dystrophy Mutation Causes Amplified Circadian and Photophobic Responses to Light in Mice
Stewart Thompson, Frederick R. Blodi, Demelza R. Larson, Michael G. Anderson, Steven F. Stasheff
Invest Ophthalmol Vis Sci. 2019 May; 60(6): 2110–2117. doi: 10.1167/iovs.19-26881
PMCID:
PMC6735810
AbstractArticlePDF–908K
6.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
7.
Mutant Fibulin-3 Causes Proteoglycan Accumulation and Impaired Diffusion Across Bruch's Membrane
Astrid Zayas-Santiago, Samuel D. Cross, James B. Stanton, Alan D. Marmorstein, Lihua Y. Marmorstein
Invest Ophthalmol Vis Sci. 2017 Jul; 58(7): 3046–3054. doi: 10.1167/iovs.17-21720
PMCID:
PMC5477800
AbstractArticlePDF–1.7M
8.
Deletion of Efemp1 Is Protective Against the Development of Sub-RPE Deposits in Mouse Eyes
James B. Stanton, Alan D. Marmorstein, Youwen Zhang, Lihua Y. Marmorstein
Invest Ophthalmol Vis Sci. 2017 Mar; 58(3): 1455–1461. doi: 10.1167/iovs.16-20955
PMCID:
PMC5361459
AbstractArticlePDF–826K
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression
Alexandra Naba, Karl R. Clauser, D. R. Mani, Steven A. Carr, Richard O. Hynes
Sci Rep. 2017; 7: 40495. Published online 2017 Jan 10. doi: 10.1038/srep40495
PMCID:
PMC5223159
AbstractArticlePDF–2.3M
11.
Homologous Transcription Factors DUX4 and DUX4c Associate with Cytoplasmic Proteins during Muscle Differentiation
Eugénie Ansseau, Jocelyn O. Eidahl, Céline Lancelot, Alexandra Tassin, Christel Matteotti, Cassandre Yip, Jian Liu, Baptiste Leroy, Céline Hubeau, Cécile Gerbaux, Samuel Cloet, Armelle Wauters, Sabrina Zorbo, Pierre Meyer, Isabelle Pirson, Dalila Laoudj-Chenivesse, Ruddy Wattiez, Scott Q. Harper, Alexandra Belayew, Frédérique Coppée
PLoS One. 2016; 11(1): e0146893. Published online 2016 Jan 27. doi: 10.1371/journal.pone.0146893
PMCID:
PMC4729438
AbstractArticlePDF–9.2M
12.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
13.
Identification of Novel SHOX Target Genes in the Developing Limb Using a Transgenic Mouse Model
Katja U. Beiser, Anne Glaser, Kerstin Kleinschmidt, Isabell Scholl, Ralph Röth, Li Li, Norbert Gretz, Gunhild Mechtersheimer, Marcel Karperien, Antonio Marchini, Wiltrud Richter, Gudrun A. Rappold
PLoS One. 2014; 9(6): e98543. Published online 2014 Jun 2. doi: 10.1371/journal.pone.0098543
PMCID:
PMC4041798
AbstractArticlePDF–9.8M
14.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
15.
Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration
Donita L. Garland, Rosario Fernandez-Godino, Inderjeet Kaur, Kaye D. Speicher, James M. Harnly, John D. Lambris, David W. Speicher, Eric A. Pierce
Hum Mol Genet. 2014 Jan 1; 23(1): 52–68. Published online 2013 Aug 13. doi: 10.1093/hmg/ddt395
PMCID:
PMC3857944
AbstractArticlePDF–1.0M
16.
Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models
Sandra Diersch, Wenzel Patrick, Melanie Szameitat, Philipp Eser, Mariel C. Paul, Barbara Seidler, Stefan Eser, Marlena Messer, Maximilian Reichert, Philipp Pagel, Irene Esposito, Roland M. Schmid, Dieter Saur, Günter Schneider
Oncotarget. 2013 Feb; 4(2): 277–288. Published online 2013 Feb 26. doi: 10.18632/oncotarget.859
PMCID:
PMC3712573
AbstractArticlePDF–7.4M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
Detection of Genes Regulated by Lmx1b During Limb Dorsalization
Jennifer M. Feenstra, Kohei Kanaya, Charmaine U Pira, Sarah E. Hoffman, Richard J. Eppey, Kerby C. Oberg
Dev Growth Differ. Author manuscript; available in PMC 2013 May 1.
Published in final edited form as: Dev Growth Differ. 2012 May; 54(4): 451–462. Published online 2012 Mar 15. doi: 10.1111/j.1440-169X.2012.01331.x
PMCID:
PMC3546822
AbstractArticlePDF–3.2M
19.
Smooth muscle–endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation
Sophie Lutter, Sherry Xie, Florence Tatin, Taija Makinen
J Cell Biol. 2012 Jun 11; 197(6): 837–849. doi: 10.1083/jcb.201110132
PMCID:
PMC3373399
AbstractArticlePDF–3.9M
20.
The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices
Alexandra Naba, Karl R. Clauser, Sebastian Hoersch, Hui Liu, Steven A. Carr, Richard O. Hynes
Mol Cell Proteomics. 2012 Apr; 11(4): M111.014647. Published online 2011 Dec 9. doi: 10.1074/mcp.M111.014647
PMCID:
PMC3322572
AbstractArticlePDF–7.3M

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