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Select item 111807761.

Deficiency of glucocorticoid receptor in bone marrow adipocytes has mild effects on bone and hematopoiesis but does not influence expansion of marrow adiposity with caloric restriction

Rebecca L. Schill, Jack Visser, Mariah L. Ashby, Ziru Li, Kenneth T. Lewis, Antonio Morales-Hernandez, Keegan S. Hoose, Jessica N. Maung, Romina M. Uranga, Hadla Hariri, Isabel D. K. Hermsmeyer, Hiroyuki Mori, Ormond A. MacDougald

Front Endocrinol (Lausanne) 2024; 15: 1397081. Published online 2024 Jun 3. doi: 10.3389/fendo.2024.1397081

PMCID:: PMC11180776

Abstract Article PDF–7.8M

Select item 109755042.

Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes

Hiroyuki Mori, Sydney K. Peterson, Rachel C. Simmermon, Katherine A. Overmyer, Akira Nishii, Emma Paulsson, Ziru Li, Annie Jen, Romina M. Uranga, Jessica N. Maung, Warren T. Yacawych, Kenneth T. Lewis, Rebecca L. Schill, Taryn Hetrick, Ryo Seino, Ken Inoki, Joshua J. Coon, Ormond A. MacDougald

Mol Metab. 2024 May; 83: 101916. Published online 2024 Mar 14. doi: 10.1016/j.molmet.2024.101916

PMCID:: PMC10975504

Abstract Article PDF–5.9M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107785604.

The Duality of Adiponectin: The Role of Sex in Atherosclerosis

Abigail E. Cullen, Ann M. Centner, Riley Deitado, Vladimir Ukhanov, Judy Muller-Delp, Gloria Salazar

Cells. 2024 Jan; 13(1): 1. Published online 2023 Dec 19. doi: 10.3390/cells13010001

PMCID:: PMC10778560

Abstract Article PDF–4.3M

Select item 106716085.

STAT3 Signalling Drives LDH Up-Regulation and Adiponectin Down-Regulation in Cachectic Adipocytes

Michele Mannelli, Bianca Bartoloni, Giulia Cantini, Elena Nencioni, Francesca Magherini, Michaela Luconi, Alessandra Modesti, Tania Gamberi, Tania Fiaschi

Int J Mol Sci. 2023 Nov; 24(22): 16343. Published online 2023 Nov 15. doi: 10.3390/ijms242216343

PMCID:: PMC10671608

Abstract Article PDF–3.9M

Select item 106198736.

Adiponectin in the mammalian host influences ticks’ acquisition of the Lyme disease pathogen Borrelia

Xiaotian Tang, Yongguo Cao, Carmen J. Booth, Gunjan Arora, Yingjun Cui, Jaqueline Matias, Erol Fikrig

PLoS Biol. 2023 Oct; 21(10): e3002331. Published online 2023 Oct 20. doi: 10.1371/journal.pbio.3002331

PMCID:: PMC10619873

Abstract Article PDF–1.9M

Select item 106059227.

AKT Mediates Adiponectin-Dependent Regulation of VSMC Phenotype

Abigail E. Cullen, Ann M. Centner, Riley Deitado, Ahmed Ismaeel, Panagiotis Koutakis, Judy Muller-Delp, Gloria Salazar

Cells. 2023 Oct; 12(20): 2493. Published online 2023 Oct 20. doi: 10.3390/cells12202493

PMCID:: PMC10605922

Abstract Article PDF–8.0M

Select item 105980538.

Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells

Toshiharu Onodera, Dae-Seok Kim, Risheng Ye, May-Yun Wang, Shiuhwei Chen, Bianca C. Field, Leon Straub, Xue-Nan Sun, Chao Li, Charlotte Lee, Megan Paredes, Clair Crewe, Shangang Zhao, Christine M. Kusminski, Ruth Gordillo, Philipp E. Scherer

Mol Metab. 2023 Dec; 78: 101821. Published online 2023 Oct 6. doi: 10.1016/j.molmet.2023.101821

PMCID:: PMC10598053

Abstract Article PDF–4.3M

Select item 105820459.

Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization

Toshiharu Onodera, May-Yun Wang, Joseph M. Rutkowski, Stanislaw Deja, Shiuhwei Chen, Michael S. Balzer, Dae-Seok Kim, Xuenan Sun, Yu A. An, Bianca C. Field, Charlotte Lee, Ei-ichi Matsuo, Monika Mizerska, Ina Sanjana, Naoto Fujiwara, Christine M. Kusminski, Ruth Gordillo, Laurent Gautron, Denise K. Marciano, Ming Chang Hu, Shawn C. Burgess, Katalin Susztak, Orson W. Moe, Philipp E. Scherer

Nat Commun. 2023; 14: 6531. Published online 2023 Oct 17. doi: 10.1038/s41467-023-42188-4

PMCID:: PMC10582045

Abstract Article PDF–4.6M

Select item 1047446310.

ER stress decreases exosome production through adiponectin/T-cadherin-dependent and -independent pathways

Keita Fukuoka, Ryohei Mineo, Shunbun Kita, Shiro Fukuda, Tomonori Okita, Emi Kawada-Horitani, Masahito Iioka, Kohei Fujii, Keitaro Kawada, Yuya Fujishima, Hitoshi Nishizawa, Norikazu Maeda, Iichiro Shimomura

J Biol Chem. 2023 Sep; 299(9): 105114. Published online 2023 Jul 29. doi: 10.1016/j.jbc.2023.105114

PMCID:: PMC10474463

Abstract Article PDF–2.2M

Select item 1046157011.

Co-occurrence of non-alcoholic steatohepatitis exacerbates psoriasis associated with decreased adiponectin expression in a murine model

Daiki Takezaki, Shin Morizane, Kenta Ikeda, Masanori Iseki, Yuma Sakamoto, Yoshio Kawakami, Taishi Hashiguchi, Yuka Shirakata, Sohji Nishina, Tomoyuki Mukai

Front Immunol. 2023; 14: 1214623. Published online 2023 Aug 14. doi: 10.3389/fimmu.2023.1214623

PMCID:: PMC10461570

Abstract Article PDF–20M

Select item 1029674512.

Emerging Role of Adiponectin/AdipoRs Signaling in Choroidal Neovascularization, Age-Related Macular Degeneration, and Diabetic Retinopathy

Mayank Choubey, Puran Bora

Biomolecules. 2023 Jun; 13(6): 982. Published online 2023 Jun 13. doi: 10.3390/biom13060982

PMCID:: PMC10296745

Abstract Article PDF–1.0M

Select item 1029430713.

Adiponectin affects the migration ability of bone marrow-derived mesenchymal stem cells via the regulation of hypoxia inducible factor 1α

Sujung Soh, Sora Han, Hye In Ka, Se Hwan Mun, Woojung Kim, Gaeun Oh, Young Yang

Cell Commun Signal. 2023; 21: 158. Published online 2023 Jun 27. doi: 10.1186/s12964-023-01143-y

Correction in:: Cell Commun Signal. 2023; 21: 194.

PMCID:: PMC10294307

Abstract Article PDF–9.9M

Select item 989198114.

AdipoRon enhances healthspan in middle‐aged obese mice: striking alleviation of myosteatosis and muscle degenerative markers

Camille M. Selvais, María A. Davis‐López de Carrizosa, Maxime Nachit, Romain Versele, Nicolas Dubuisson, Laurence Noel, Justine Gillard, Isabelle A. Leclercq, Sonia M. Brichard, Michel Abou‐Samra

J Cachexia Sarcopenia Muscle. 2023 Feb; 14(1): 464–478. Published online 2022 Dec 13. doi: 10.1002/jcsm.13148

PMCID:: PMC9891981

Abstract Article PDF–6.2M

Select item 975516215.

Loss-of-function N178T variant of the human P2Y₄ receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis

Michael Horckmans, Esteban Diaz Villamil, Céline Verdier, Henrik Laurell, Jean-Bernard Ruidavets, Lucas De Roeck, Guillaume Combes, Laurent O. Martinez, Didier Communi

Front Pharmacol. 2022; 13: 1049696. Published online 2022 Dec 2. doi: 10.3389/fphar.2022.1049696

PMCID:: PMC9755162

Abstract Article PDF–1.6M

Select item 970658216.

SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex

Huanming Shen, Ting He, Shuai Wang, Lingfeng Hou, Yixin Wei, Yunjia Liu, Chunli Mo, Zehang Zhao, WeiXin You, Huiling Guo, Boan Li

Theranostics. 2022; 12(18): 7699–7716. Published online 2022 Nov 7. doi: 10.7150/thno.77102

PMCID:: PMC9706582

Abstract Article PDF–2.5M

Select item 968405617.

Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling

Tomonori Okita, Shunbun Kita, Shiro Fukuda, Keita Fukuoka, Emi Kawada-Horitani, Masahito Iioka, Yuto Nakamura, Yuya Fujishima, Hitoshi Nishizawa, Dan Kawamori, Taka-aki Matsuoka, Maeda Norikazu, Iichiro Shimomura

iScience. 2022 Nov 18; 25(11): 105404. Published online 2022 Nov 7. doi: 10.1016/j.isci.2022.105404

PMCID:: PMC9684056

Abstract Article PDF–3.1M

Select item 967547218.

Constitutive bone marrow adipocytes suppress local bone formation

Ziru Li, Devika P. Bagchi, Junxiong Zhu, Emily Bowers, Hui Yu, Julie Hardij, Hiroyuki Mori, Katrina Granger, Jon Skjaerlund, Gurjit Mandair, Simin Abrishami, Kanakadurga Singer, Kurt D. Hankenson, Clifford J. Rosen, Ormond A. MacDougald

JCI Insight. 2022 Nov 8; 7(21): e160915. Published online 2022 Nov 8. doi: 10.1172/jci.insight.160915

PMCID:: PMC9675472

Abstract Article PDF–29M

Select item 955516919.

Central role of PD-L1 in cardioprotection resulting from P2Y₄ nucleotide receptor loss

Michael Horckmans, Esteban Diaz Villamil, Mariaelvy Bianchini, Lucas De Roeck, Didier Communi

Front Immunol. 2022; 13: 1006934. Published online 2022 Sep 28. doi: 10.3389/fimmu.2022.1006934

Correction in:: Front Immunol. 2022; 13: 1061958.

PMCID:: PMC9555169

Abstract Article PDF–6.2M

Select item 953491120.

Congenital adiponectin deficiency mitigates high-fat-diet-induced obesity in gonadally intact male and female, but not in ovariectomized mice

Christian A. Unger, Ahmed K. Aladhami, Marion C. Hope, III, Sahar Pourhoseini, Mitzi Nagarkatti, Owen P. McGuinness, E. Angela Murphy, Kandy T. Velázquez, Reilly T. Enos

Sci Rep. 2022; 12: 16668. Published online 2022 Oct 5. doi: 10.1038/s41598-022-21228-x

PMCID:: PMC9534911

Abstract Article PDF–6.5M

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