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Select item 112872551.

Conformational dynamics underlying atypical chemokine receptor 3 activation

Omolade Otun, Christelle Aljamous, Elise Del Nero, Marta Arimont-Segura, Reggie Bosma, Barbara Zarzycka, Tristan Girbau, Cédric Leyrat, Chris de Graaf, Rob Leurs, Thierry Durroux, Sébastien Granier, Xiaojing Cong, Cherine Bechara

Proc Natl Acad Sci U S A. 2024 Jul 23; 121(30): e2404000121. Published online 2024 Jul 15. doi: 10.1073/pnas.2404000121

PMCID:: PMC11287255

Abstract Article PDF–5.9M

Select item 110339582.

Atypical Chemokine Receptor 3 “Senses” CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation

Christopher T. Schafer, Qiuyan Chen, John J. G. Tesmer, Tracy M. Handel

Mol Pharmacol. 2023 Oct; 104(4): 174–186. Published online 2023 Oct. doi: 10.1124/molpharm.123.000710

PMCID:: PMC11033958

Abstract Article PDF–1.5M

Select item 109332013.

Crosstalk between purinergic receptor P2Y₁₁ and chemokine receptor CXCR7 is regulated by CXCR4 in human macrophages

Dominik Klaver, Hubert Gander, Beatrice Frena, Marco Amato, Martin Thurnher

Cell Mol Life Sci. 2024 Dec; 81(1): 132. Published online 2024 Mar 13. doi: 10.1007/s00018-024-05158-7

PMCID:: PMC10933201

Abstract Article PDF–4.5M

Select item 106368254.

Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer

Tianshi Wang, Dehai Wang, Yanan Sun, Ting Zhuang, Xin Li, Huijie Yang, Yifeng Zang, Ziping Liu, Penghe Yang, Chenmiao Zhang, Jiayao Cui, Mingxi Fu, Shuqing Zhang, Peng Su, Zhongbo Li, Jian Zhu, Yinlu Ding

J Exp Clin Cancer Res. 2023; 42: 297. Published online 2023 Nov 10. doi: 10.1186/s13046-023-02870-3

PMCID:: PMC10636825

Abstract Article PDF–5.5M

Select item 103675675.

CXCL12-CXCR4/CXCR7 Axis in Cancer: from Mechanisms to Clinical Applications

Yaru Yang, Jiayan Li, Wangrui Lei, Haiying Wang, Yunfeng Ni, Yanqing Liu, Huanle Yan, Yifan Tian, Zheng Wang, Zhi Yang, Shulin Yang, Yang Yang, Qiang Wang

Int J Biol Sci. 2023; 19(11): 3341–3359. Published online 2023 Jun 26. doi: 10.7150/ijbs.82317

PMCID:: PMC10367567

Abstract Article PDF–2.2M

Select item 102733216.

CXCR7 as a novel therapeutic target for advanced prostate cancer

Galina Gritsina, Jindan Yu

Oncogene. Author manuscript; available in PMC 2023 Jun 16.

Published in final edited form as: Oncogene. 2023 Mar; 42(11): 785–792. Published online 2023 Feb 9. doi: 10.1038/s41388-023-02597-7

PMCID:: PMC10273321

Abstract Article PDF–557K

Select item 102287907.

Reassessing the adrenomedullin scavenging function of ACKR3 in lymphatic endothelial cells

Elena C. Sigmund, Aline Bauer, Barbara D. Jakobs, Hazal Tatliadim, Carlotta Tacconi, Marcus Thelen, Daniel F. Legler, Cornelia Halin

PLoS One. 2023; 18(5): e0285597. Published online 2023 May 30. doi: 10.1371/journal.pone.0285597

PMCID:: PMC10228790

Abstract Article PDF–2.6M

Select item 98785628.

ACKR3 promotes CXCL12/CXCR4-mediated cell-to-cell-induced lymphoma migration through LTB4 production

Paola Antonello, Diego U. Pizzagalli, Mathilde Foglierini, Serena Melgrati, Egle Radice, Sylvia Thelen, Marcus Thelen

Front Immunol. 2022; 13: 1067885. Published online 2023 Jan 12. doi: 10.3389/fimmu.2022.1067885

PMCID:: PMC9878562

Abstract Article PDF–15M

Select item 96227509.

Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis

Juan Yang, Rong-rong Miao, Ya-nan Li, Ting Pan, Shu-hua Wu, Xian-jun Qu, Shu-xiang Cui

Acta Pharmacol Sin. 2022 Nov; 43(11): 2967–2976. Published online 2022 Apr 1. doi: 10.1038/s41401-022-00901-x

PMCID:: PMC9622750

Abstract Article PDF–6.6M

Select item 957002010.

Crosstalk between CXCR4/ACKR3 and EGFR Signaling in Breast Cancer Cells

Maria Neves, Viviana Marolda, Federico Mayor, Jr., Petronila Penela

Int J Mol Sci. 2022 Oct; 23(19): 11887. Published online 2022 Oct 6. doi: 10.3390/ijms231911887

PMCID:: PMC9570020

Abstract Article PDF–2.9M

Select item 927693911.

Emerging Roles of the Atypical Chemokine Receptor 3 (ACKR3) in Cardiovascular Diseases

Vincent Duval, Paul Alayrac, Jean-Sébastien Silvestre, Angélique Levoye

Front Endocrinol (Lausanne) 2022; 13: 906586. Published online 2022 Jun 29. doi: 10.3389/fendo.2022.906586

PMCID:: PMC9276939

Abstract Article PDF–2.5M

Select item 923162312.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 922375413.

Selective Elimination of Senescent Fibroblasts by Targeting the Cell Surface Protein ACKR3

Kento Takaya, Toru Asou, Kazuo Kishi

Int J Mol Sci. 2022 Jun; 23(12): 6531. Published online 2022 Jun 10. doi: 10.3390/ijms23126531

PMCID:: PMC9223754

Abstract Article PDF–1.6M

Select item 917986214.

The CXCL12/CXCR4/ACKR3 Signaling Axis Regulates PKM2 and Glycolysis

Kathryn E. Luker, Gary D. Luker

Cells. 2022 Jun; 11(11): 1775. Published online 2022 May 28. doi: 10.3390/cells11111775

PMCID:: PMC9179862

Abstract Article PDF–3.3M

Select item 897402515.

MicroRNA-200b-3p restrains gastric cancer cell proliferation, migration, and invasion via C-X-C motif chemokine ligand 12/CXC chemokine receptor 7 axis

Dinuo Li, Qiang Li

Bioengineered. 2022; 13(3): 6509–6520. Published online 2022 Feb 28. doi: 10.1080/21655979.2022.2034585

PMCID:: PMC8974025

Abstract Article PDF–2.6M

Select item 897370216.

C-X-C motif chemokine ligand 12 (CXCL12)/C-X-C motif chemokine receptor 7(CXCR7) regulates epithelial-mesenchymal transition process and promotes the metastasis of esophageal cancer by activating signal transducer and activator of transcription 3 (STAT3) pathway

Jing Guo, Chang-Yong Tong, Jian-Guang Shi, Xin-Jian Li

Bioengineered. 2022; 13(3): 7425–7438. Published online 2022 Mar 9. doi: 10.1080/21655979.2022.2048984

PMCID:: PMC8973702

Abstract Article PDF–4.0M

Select item 836918417.

Overexpression of CXCR7 is a Novel Indicator for Enzalutamide Resistance in Castration-Resistant Prostate Cancer Patients

Yong Luo, Qiankun Li, Xiaobing Yang, Dechao Wei, Bingfu Feng, Mingchuan Li, Yili Han, Jiahui Zhao, Yunhua Lin, Qing Li, Zhu Hou, Hongyu Zhuang, Yongguang Jiang

Dis Markers. 2021; 2021: 6649579. Published online 2021 Aug 6. doi: 10.1155/2021/6649579

PMCID:: PMC8369184

Abstract Article PDF–733K

Select item 831631018.

Class A G protein-coupled receptors assemble into functional higher-order hetero-oligomers

Xianlong Gao, Garrett A. Enten, Anthony J. DeSantis, Matthias Majetschak

FEBS Lett. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: FEBS Lett. 2021 Jul; 595(14): 1863–1875. Published online 2021 Jun 11. doi: 10.1002/1873-3468.14135

PMCID:: PMC8316310

Abstract Article PDF–1.4M

Select item 831332719.

miR-100 Suppresses the Proliferation, Invasion, and Migration of Hepatocellular Carcinoma Cells via Targeting CXCR7

Yiman Ge, Jia Shu, Gang Shi, Fuguo Yan, Yejing Li, Hangliang Ding

J Immunol Res. 2021; 2021: 9920786. Published online 2021 Jul 17. doi: 10.1155/2021/9920786

PMCID:: PMC8313327

Abstract Article PDF–2.5M

Select item 818522420.

D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling

Shanshan Song, Bin Liu, Habibie Habibie, Jelle van den Bor, Martine J. Smit, Reinoud Gosens, Xinhui Wu, Corry-Anke Brandsma, Robbert H. Cool, Hidde J. Haisma, Gerrit J. Poelarends, Barbro N. Melgert

EBioMedicine. 2021 Jun; 68: 103412. Published online 2021 Jun 4. doi: 10.1016/j.ebiom.2021.103412