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Items: 1 to 20 of 87

1.
Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform
Dirk H Siepe, Lukas T Henneberg, Steven C Wilson, Gaelen T Hess, Michael C Bassik, Kai Zinn, K Christopher Garcia
eLife. 2022; 11: e81398. Published online 2022 Sep 30. doi: 10.7554/eLife.81398
PMCID:
PMC9578707
AbstractArticlePDF–3.3M
2.
Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCγ1 axis
Junhua Xu, Yanfeng Zhong, Haoyang Yin, John Linneman, Yixuan Luo, Sijian Xia, Qinyi Xia, Lei Yang, Xingtao Huang, Kang Kang, Jun Wang, Yanqin Niu, Li Li, Deming Gou
J Hypertens. 2022 Sep; 40(9): 1795–1807. Published online 2022 Jul 25. doi: 10.1097/HJH.0000000000003220
PMCID:
PMC9451921
AbstractArticlePDF–3.6M
3.
PTPRD and CNTNAP2 as markers of tumor aggressiveness in oligodendrogliomas
Kirsi J. Rautajoki, Serafiina Jaatinen, Aliisa M. Tiihonen, Matti Annala, Elisa M. Vuorinen, Anni Kivinen, Minna J. Rauhala, Kendra K. Maass, Kristian W. Pajtler, Olli Yli-Harja, Pauli Helén, Joonas Haapasalo, Hannu Haapasalo, Wei Zhang, Matti Nykter
Sci Rep. 2022; 12: 14083. Published online 2022 Aug 18. doi: 10.1038/s41598-022-14977-2
PMCID:
PMC9388569
AbstractArticlePDF–3.2M
4.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
5.
Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development
Ian M. Henderson, Fanxun Zeng, Nazmul H. Bhuiyan, Dan Luo, Maria Martinez, Jane Smoake, Fangchao Bi, Chamani Perera, David Johnson, Thomas E. Prisinzano, Wei Wang, George R. Uhl
Biochem Pharmacol. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Biochem Pharmacol. 2022 Jan; 195: 114868. Published online 2021 Dec 2. doi: 10.1016/j.bcp.2021.114868
PMCID:
PMC9248268
AbstractArticlePDF–947K
6.
Identification and validation of tissue or ctDNA PTPRD phosphatase domain deleterious mutations as prognostic and predictive biomarkers for immune checkpoint inhibitors in non-squamous NSCLC
Yiting Sun, Jianchun Duan, Wenfeng Fang, Zhijie Wang, Xinyang Du, Xin Wang, Chengcheng Li, Shangli Cai, Jie Zhao, Sini Li, Li Zhang, Hua Bai, Jie Wang
BMC Med. 2021; 19: 239. Published online 2021 Oct 7. doi: 10.1186/s12916-021-02075-5
PMCID:
PMC8496052
AbstractArticlePDF–4.2M
7.
DIAPH2, PTPRD and HIC1 Gene Polymorphisms and Laryngeal Cancer Risk
Mirosław Śnit, Maciej Misiołek, Wojciech Ścierski, Anna Koniewska, Grażyna Stryjewska-Makuch, Sławomir Okła, Władysław Grzeszczak
Int J Environ Res Public Health. 2021 Jul; 18(14): 7486. Published online 2021 Jul 13. doi: 10.3390/ijerph18147486
PMCID:
PMC8305316
AbstractArticlePDF–324K
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
Protein tyrosine phosphatase receptor type D gene promotes radiosensitivity via STAT3 dephosphorylation in nasopharyngeal carcinoma
Yanling Lin, Xiaohan Zhou, Kaifan Yang, Yuting Chen, Lingzhi Wang, Wenxiao Luo, Yujiang Li, Jinrong Liao, Yingtong Zhou, Yiming Lei, Yanting Zhang, Dehua Wu, Longmei Cai
Oncogene. 2021; 40(17): 3101–3117. Published online 2021 Apr 6. doi: 10.1038/s41388-021-01768-8
PMCID:
PMC8084736
AbstractArticlePDF–6.6M
10.
The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex
Xin Wang, Wei Jiang, Shuo Luo, Xiaoyu Yang, Changnan Wang, Bingying Wang, Yongjun Dang, Yin Shen, Dengke K. Ma
Mol Brain. 2021; 14: 54. Published online 2021 Mar 16. doi: 10.1186/s13041-021-00767-w
PMCID:
PMC7962252
AbstractArticlePDF–6.5M
11.
MiR-324-5p/PTPRD/CEBPD axis promotes papillary thyroid carcinoma progression via microenvironment alteration
Yanhua Yang, Shujun Xia, Lu Zhang, Wenhan Wang, Lin Chen, Weiwei Zhan
Cancer Biol Ther. 2020; 21(6): 522–532. Published online 2020 Mar 10. doi: 10.1080/15384047.2020.1736465
PMCID:
PMC7515492
AbstractArticlePDF–5.1M
12.
Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis
Jingjiao Li, Mingquan Guo, Xiaoxu Tian, Xin Wang, Xing Yang, Ping Wu, Chengrong Liu, Zixuan Xiao, Yafei Qu, Yue Yin, Chunxia Wang, Yucai Zhang, Zhaoqin Zhu, Zhenshan Liu, Chao Peng, Tongyu Zhu, Qiming Liang
Med (N Y) 2021 Jan 15; 2(1): 99–112.e7. Published online 2020 Jul 21. doi: 10.1016/j.medj.2020.07.002
PMCID:
PMC7373048
AbstractArticlePDF–3.8M
13.
PTPRD-inactivation-induced CXCL8 promotes angiogenesis and metastasis in gastric cancer and is inhibited by metformin
Won Jung Bae, Ji Mi Ahn, Hye Eun Byeon, Seokwhi Kim, Dakeun Lee
J Exp Clin Cancer Res. 2019; 38: 484. Published online 2019 Dec 5. doi: 10.1186/s13046-019-1469-4
PMCID:
PMC6896474
AbstractArticlePDF–1.9M
14.
Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis
Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu
iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057
PMCID:
PMC6831851
AbstractArticlePDF–9.8M
15.
Interleukin-1 Receptor Accessory Protein Organizes Neuronal Synaptogenesis as a Cell Adhesion Molecule
Tomoyuki Yoshida, Tomoko Shiroshima, Sung-Jin Lee, Misato Yasumura, Takeshi Uemura, Xigui Chen, Yoichiro Iwakura, Masayoshi Mishina
J Neurosci. 2012 Feb 22; 32(8): 2588–2600. doi: 10.1523/JNEUROSCI.4637-11.2012
PMCID:
PMC6621890
AbstractArticlePDF–5.2M
16.
Genetic overlap between endometriosis and endometrial cancer: evidence from cross‐disease genetic correlation and GWAS meta‐analyses
Jodie N. Painter, Tracy A. O'Mara, Andrew P. Morris, Timothy H. T. Cheng, Maggie Gorman, Lynn Martin, Shirley Hodson, Angela Jones, Nicholas G. Martin, Scott Gordon, Anjali K. Henders, John Attia, Mark McEvoy, Elizabeth G. Holliday, Rodney J. Scott, Penelope M. Webb, Peter A. Fasching, Matthias W. Beckmann, Arif B. Ekici, Alexander Hein, Matthias Rübner, Per Hall, Kamila Czene, Thilo Dörk, Matthias Dürst, Peter Hillemanns, Ingo Runnebaum, Diether Lambrechts, Frederic Amant, Daniela Annibali, Jeroen Depreeuw, Adriaan Vanderstichele, Ellen L. Goode, Julie M. Cunningham, Sean C. Dowdy, Stacey J. Winham, Jone Trovik, Erling Hoivik, Henrica M. J. Werner, Camilla Krakstad, Katie Ashton, Geoffrey Otton, Tony Proietto, Emma Tham, Miriam Mints, Shahana Ahmed, Catherine S. Healey, Mitul Shah, Paul D. P. Pharoah, Alison M. Dunning, Joe Dennis, Manjeet K. Bolla, Kyriaki Michailidou, Qin Wang, Jonathan P. Tyrer, John L. Hopper, Julian Peto, Anthony J. Swerdlow, Barbara Burwinkel, Hermann Brenner, Alfons Meindl, Hiltrud Brauch, Annika Lindblom, Jenny Chang‐Claude, Fergus J. Couch, Graham G. Giles, Vessela N. Kristensen, Angela Cox, Krina T. Zondervan, Dale R. Nyholt, Stuart MacGregor, Grant W. Montgomery, Ian Tomlinson, Douglas F. Easton, Deborah J. Thompson, Amanda B. Spurdle
Cancer Med. 2018 May; 7(5): 1978–1987. Published online 2018 Apr 2. doi: 10.1002/cam4.1445
PMCID:
PMC5943470
AbstractArticlePDF–118K
17.
Structural basis of trans-synaptic interactions between PTPδ and SALMs for inducing synapse formation
Sakurako Goto-Ito, Atsushi Yamagata, Yusuke Sato, Takeshi Uemura, Tomoko Shiroshima, Asami Maeda, Ayako Imai, Hisashi Mori, Tomoyuki Yoshida, Shuya Fukai
Nat Commun. 2018; 9: 269. Published online 2018 Jan 18. doi: 10.1038/s41467-017-02417-z
PMCID:
PMC5773591
AbstractArticlePDF–1.8M
18.
Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation
Zhaohan Lin, Jianmei Liu, Huandi Ding, Fei Xu, Heli Liu
Nat Commun. 2018; 9: 268. Published online 2018 Jan 18. doi: 10.1038/s41467-017-02414-2
PMCID:
PMC5773555
AbstractArticlePDF–3.5M
19.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
20.
Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies
Lori B Chibnik, Charles C White, Shubhabrata Mukherjee, Towfique Raj, Lei Yu, Eric B. Larson, Thomas J. Montine, C. Dirk Keene, Joshua Sonnen, Julie A. Schneider, Paul K. Crane, Joshua M. Shulman, David A Bennett, Philip L De Jager
Mol Psychiatry. Author manuscript; available in PMC 2018 Jul 3.
Published in final edited form as: Mol Psychiatry. 2018 Jun; 23(6): 1521–1529. Published online 2017 Mar 21. doi: 10.1038/mp.2017.20
PMCID:
PMC5608624
AbstractArticlePDF–1.1M

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