PMC Links for GEO Profiles (Select 71972983) - PMC

Select item 107890311.

Lnc-PSMA8-1 activated by GEFT promotes rhabdomyosarcoma progression via upregulation of mTOR expression by sponging miR-144-3p

Lian Meng, Hao Shang, Qianqian Liu, Zhenzhen Li, Xiaomeng Wang, Qianru Li, Feng Li, Zhenguo Zhao, Chunxia Liu

BMC Cancer. 2024; 24: 79. Published online 2024 Jan 15. doi: 10.1186/s12885-023-11798-y

PMCID:: PMC10789031

Abstract Article PDF–9.7M

Select item 88970222.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 55316114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 51050845.

Kinetics of recruitment and allosteric activation of ARHGEF25 isoforms by the heterotrimeric G-protein Gαq

Jakobus van Unen, Taofei Yin, Yi I. Wu, Marieke Mastop, Theodorus W. J. Gadella, Jr., Joachim Goedhart

Sci Rep. 2016; 6: 36825. Published online 2016 Nov 11. doi: 10.1038/srep36825

PMCID:: PMC5105084

Abstract Article PDF–2.2M

Select item 46571616.

PAK4 promotes kinase-independent stabilization of RhoU to modulate cell adhesion

Anna E. Dart, Gary M. Box, William Court, Madeline E. Gale, John P. Brown, Sarah E. Pinder, Suzanne A. Eccles, Claire M. Wells

J Cell Biol. 2015 Nov 23; 211(4): 863–879. doi: 10.1083/jcb.201501072

PMCID:: PMC4657161

Abstract Article PDF–8.1M

Select item 45929717.

Plasma membrane restricted RhoGEF activity is sufficient for RhoA-mediated actin polymerization

Jakobus van Unen, Nathalie R. Reinhard, Taofei Yin, Yi I. Wu, Marten Postma, Theodorus W.J. Gadella, Joachim Goedhart

Sci Rep. 2015; 5: 14693. Published online 2015 Oct 5. doi: 10.1038/srep14693

PMCID:: PMC4592971

Abstract Article PDF–2.0M

Select item 40142418.

Overexpression of GEFT, a Rho family guanine nucleotide exchange factor, predicts poor prognosis in patients with rhabdomyosarcoma

Chao Sun, Chunxia Liu, Shugang Li, Hongan Li, Yuanyuan Wang, Yuwen Xie, Bingcheng Li, Xiaobin Cui, Yunzhao Chen, Wenjie Zhang, Feng Li

Int J Clin Exp Pathol. 2014; 7(4): 1606–1615. Published online 2014 Mar 15.

PMCID:: PMC4014241

Abstract Article PDF–1.1M

Select item 37225679.

Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location

Joachim Goedhart, Jakobus van Unen, Merel J. W. Adjobo-Hermans, Theodorus W. J. Gadella, Jr.

Sci Rep. 2013; 3: 2284. Published online 2013 Jul 25. doi: 10.1038/srep02284

PMCID:: PMC3722567

Abstract Article PDF–4.9M

Select item 321113810.

p63RhoGEF Couples G_αq/11-mediated Signaling to Ca²⁺ Sensitization of Vascular Smooth Muscle Contractility

Ko Momotani, Mykhaylo V. Artamonov, Darkhan Utepbergenov, Urszula Derewenda, Zygmunt S. Derewenda, Avril V. Somlyo

Circ Res. Author manuscript; available in PMC 2012 Oct 14.

Published in final edited form as: Circ Res. 2011 Oct 14; 109(9): 993–1002. Published online 2011 Sep 1. doi: 10.1161/CIRCRESAHA.111.248898

PMCID:: PMC3211138

Abstract Article PDF–1.2M

Select item 319078911.

Plasma Membrane Association of p63 Rho Guanine Nucleotide Exchange Factor (p63RhoGEF) Is Mediated by Palmitoylation and Is Required for Basal Activity in Cells

Mohamed Aittaleb, Akiyuki Nishimura, Maurine E. Linder, John J. G. Tesmer

J Biol Chem. 2011 Sep 30; 286(39): 34448–34456. Published online 2011 Aug 10. doi: 10.1074/jbc.M111.273342

PMCID:: PMC3190789

Abstract Article PDF–3.8M

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 291206013.

Identification of RanBP 9/10 as Interacting Partners for Protein Kinase C (PKC) γ/δ and the D₁ Dopamine Receptor: Regulation of PKC-Mediated Receptor Phosphorylation

Elizabeth B. Rex, Michele L. Rankin, Yu Yang, Quansheng Lu, Charles R. Gerfen, Pedro A. Jose, David R. Sibley

Mol Pharmacol. 2010 Jul; 78(1): 69–80. doi: 10.1124/mol.110.063727

PMCID:: PMC2912060

Abstract Article PDF–2.3M

Select item 260362714.

MLK3 limits activated Gαq signaling to Rho by binding to p63RhoGEF

Katherine I. Swenson-Fields, Joshua C. Sandquist, Jessica Rossol-Allison, Irene C. Blat, Krister Wennerberg, Keith Burridge, Anthony R. Means

Mol Cell. Author manuscript; available in PMC 2009 Oct 10.

Published in final edited form as: Mol Cell. 2008 Oct 10; 32(1): 43–56. doi: 10.1016/j.molcel.2008.09.007

PMCID:: PMC2603627

Abstract Article PDF–2.3M

Select item 259639515.

Assembly of High Order Gα_q-Effector Complexes with RGS Proteins

Aruna Shankaranarayanan, David M. Thal, Valerie M. Tesmer, David L. Roman, Richard R. Neubig, Tohru Kozasa, John J. G. Tesmer

J Biol Chem. 2008 Dec 12; 283(50): 34923–34934. doi: 10.1074/jbc.M805860200

PMCID:: PMC2596395

Abstract Article PDF–842K

Select item 131695316.

Modulation of Muscle Regeneration, Myogenesis, and Adipogenesis by the Rho Family Guanine Nucleotide Exchange Factor GEFT

Brad A. Bryan, Dianne C. Mitchell, Lei Zhao, Wenbin Ma, Lewis J. Stafford, Ba-Bie Teng, Mingyao Liu

Mol Cell Biol. 2005 Dec; 25(24): 11089–11101. doi: 10.1128/MCB.25.24.11089-11101.2005

PMCID:: PMC1316953

Abstract Article PDF–641K

Select item 13924117.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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