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Select item 112286941.

SP1‑mediated ADAMTS5 transcription promotes IL‑1β‑induced chondrocyte injury via Wnt/β‑catenin pathway in osteoarthritis

Xiaoting Hao, Xiaxia Wu

Mol Med Rep. 2024 Aug; 30(2): 149. Published online 2024 Jun 26. doi: 10.3892/mmr.2024.13273

PMCID:: PMC11228694

Abstract Article PDF–7.0M

Select item 111663992.

MUTATED RAS INDUCED PLD1 GENE EXPRESSION THROUGH INCREASED Sp1 TRASCRIPTION FACTOR

SIQIANG GAO, MASASHI MURAKAMI, HIROMI ITO, AYAKO FURUHATA, KAYO YOSHIDA, YOKO TAGAWA, KAZUMI HAGIWARA, AKIRA TAKAGI, TETSUHITO KOJIMA, MOTOSHI SUZUKI, YOSHIKO BANNO, YOSHINORI NOZAWA, TAKASHI MURATE

Nagoya J Med Sci. 2009 Aug; 71(3-4): 127–136.

PMCID:: PMC11166399

Abstract Article PDF–1.7M

Select item 111591873.

Transcription factor Sp1 regulates expression of cancer‐associated molecule CD147 in human lung cancer

Ling‐Min Kong, Cheng‐Gong Liao, Fei Fei, Xu Guo, Jin‐Liang Xing, Zhi‐Nan Chen

Cancer Sci. 2010 Jun; 101(6): 1463–1470. Published online 2010 Mar 6. doi: 10.1111/j.1349-7006.2010.01554.x

PMCID:: PMC11159187

Abstract Article PDF–617K

Select item 111360734.

Role of transcriptional factors Sp1, c-Rel, and c-Jun in LPS-induced C/EBPδ gene expression of mouse macrophages

Y.-W. Liu, C.-C. Chen, J.-M. Wang, W.-C. Chang, Y.-C. Huang, S.-Y. Chung, B.-K. Chen, J.-J. Hung

Cell Mol Life Sci. 2007 Dec; 64(24): 3282–3294. Published online 2007 Oct 29. doi: 10.1007/s00018-007-7375-5

PMCID:: PMC11136073

Abstract Article PDF–1.2M

Select item 111155555.

Involvement of aryl hydrocarbon receptor nuclear translocator in EGF-induced c-Jun/Sp1-mediated gene expression

Wan-Chen Huang, Shu-Ting Chen, Wei-Chiao Chang, Kwang-Yu Chang, Wen-Chang Chang, Ben-Kuen Chen

Cell Mol Life Sci. 2010 Oct; 67(20): 3523–3533. Published online 2010 May 28. doi: 10.1007/s00018-010-0392-9

PMCID:: PMC11115555

Abstract Article PDF–591K

Select item 110273506.

The histone lysine acetyltransferase KAT2B inhibits cholangiocarcinoma growth: evidence for interaction with SP1 to regulate NF2-YAP signaling

Wenbo Ma, Jinqiang Zhang, Weina Chen, Nianli Liu, Tong Wu

J Exp Clin Cancer Res. 2024; 43: 117. Published online 2024 Apr 19. doi: 10.1186/s13046-024-03036-5

PMCID:: PMC11027350

Abstract Article PDF–4.4M

Select item 109706217.

SP1 Gene Methylation in Head and Neck Squamous Cell Cancer in HPV-Negative Patients

Enar Jumaniyazova, Anna Aghajanyan, Sergey Kurevlev, Leyla Tskhovrebova, Andrey Makarov, Konstantin Gordon, Anastasiya Lokhonina, Timur Fatkhudinov

Genes (Basel) 2024 Mar; 15(3): 281. Published online 2024 Feb 23. doi: 10.3390/genes15030281

PMCID:: PMC10970621

Abstract Article PDF–249K

Select item 109364408.

Sp1 facilitates continued HSV-1 gene expression in the absence of key viral transactivators

Catherine N. Sodroski, Hyung Suk Oh, Shu-Fan Chou, David M. Knipe

mBio. 2024 Mar; 15(3): e03479-23. Published online 2024 Feb 13. doi: 10.1128/mbio.03479-23

PMCID:: PMC10936440

Abstract Article PDF–1.7M

Select item 109113519.

Interaction of Sp1 and Setd8 promotes vascular smooth muscle cells apoptosis by activating Mark4 in vascular calcification

Yun Li, Meijuan Cheng, Jingjing Jin, Dongxue Zhang, Shenglei Zhang, Yaling Bai, Jinsheng Xu

Aging (Albany NY) 2024 Feb 15; 16(3): 2438–2456. Published online 2024 Feb 1. doi: 10.18632/aging.205492

PMCID:: PMC10911351

Abstract Article PDF–2.4M

Select item 1087869110.

Transcriptional regulation of SARS-CoV-2 receptor ACE2 by SP1

Hui Han, Rong-Hua Luo, Xin-Yan Long, Li-Qiong Wang, Qian Zhu, Xin-Yue Tang, Rui Zhu, Yi-Cheng Ma, Yong-Tang Zheng, Cheng-Gang Zou

eLife. 2024; 13: e85985. Published online 2024 Feb 20. doi: 10.7554/eLife.85985

PMCID:: PMC10878691

Abstract Article PDF–3.6M

Select item 1087452811.

RBBP7, regulated by SP1, enhances the Warburg effect to facilitate the proliferation of hepatocellular carcinoma cells via PI3K/AKT signaling

Yuan Fang, WeiQiang Tang, Siming Qu, ZhiTao Li, XiaoLi Zhang, YingLei Miao, Zhong Zeng, HanFei Huang

J Transl Med. 2024; 22: 170. Published online 2024 Feb 18. doi: 10.1186/s12967-024-04964-8

PMCID:: PMC10874528

Abstract Article PDF–14M

Select item 1084716712.

KLF6 activates Sp1-mediated prolidase transcription during TGF-β₁ signaling

Ireti Eni-Aganga, Zeljka Miletic Lanaghan, Farah Ismail, Olga Korolkova, Jeffery Shawn Goodwin, Muthukumar Balasubramaniam, Chandravanu Dash, Jui Pandhare

J Biol Chem. 2024 Feb; 300(2): 105605. Published online 2023 Dec 28. doi: 10.1016/j.jbc.2023.105605

PMCID:: PMC10847167

Abstract Article PDF–3.8M

Select item 1082462413.

Translation regulatory long non‐coding RNA 1 negatively regulates cell radiosensitivity via the miR‐22‐3p/SP1 axis in non‐small cell lung cancer

Ming Zhong, Zheng Fang, Weixi Guo, Xiuyi Yu

Clin Respir J. 2024 Jan; 18(1): e13734. Published online 2024 Jan 29. doi: 10.1111/crj.13734

PMCID:: PMC10824624

Abstract Article PDF–3.1M

Select item 1081909614.

SP1‐activated USP27X‐AS1 promotes hepatocellular carcinoma progression via USP7‐mediated AKT stabilisation

Chen Su, Haoquan Zhang, Jie Mo, Zhibin Liao, Bixiang Zhang, Peng Zhu

Clin Transl Med. 2024 Jan; 14(1): e1563. Published online 2024 Jan 27. doi: 10.1002/ctm2.1563

PMCID:: PMC10819096

Abstract Article PDF–16M

Select item 1068772715.

Effect of NFATc2- and Sp1-mediated TNFalpha Regulation on the Proliferation and Migration Behavior of Pancreatic Cancer Cells

MANUELA MALSY, BERNHARD GRAF, ELISABETH BRUENDL, CONSTANTIN MAIER-STOCKER, ANIKA BUNDSCHERER

Cancer Genomics Proteomics. 2023 Nov-Dec; 20(6 Suppl): 706–711. Published online 2023 Nov 3. doi: 10.21873/cgp.20417

PMCID:: PMC10687727

Abstract Article PDF–847K

Select item 1058342916.

KDM4C-mediated senescence defense is a targetable vulnerability in gastric cancer harboring TP53 mutations

Kaiqing Wang, Zhicheng Gong, Yanyan Chen, Meimei Zhang, Suzeng Wang, Surui Yao, Zhihui Liu, Zhaohui Huang, Bojian Fei

Clin Epigenetics. 2023; 15: 163. Published online 2023 Oct 17. doi: 10.1186/s13148-023-01579-6

PMCID:: PMC10583429

Abstract Article PDF–6.1M

Select item 1058141917.

Midline 1 interacting protein 1 promotes cancer metastasis through FOS-like 1-mediated matrix metalloproteinase 9 signaling in HCC

Yung-Tuen Chiu, Abdullah Husain, Karen Man-Fong Sze, Daniel Wai-Hung Ho, Eliana Mary Senires Suarez, Xia Wang, Eva Lee, Hoi-Tang Ma, Joyce Man-Fong Lee, Lo-Kong Chan, Irene Oi-Lin Ng

Hepatology. 2023 Nov; 78(5): 1368–1383. Published online 2023 Jan 13. doi: 10.1097/HEP.0000000000000266

PMCID:: PMC10581419

Abstract Article PDF–3.2M

Select item 1051810018.

LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter

Ganglin Ren, Hongyan Li, Dan Hong, Fangyu Hu, Rongjia Jin, Shuang Wu, Wenhao Sun, Honglei Jin, Lingling Zhao, Xiaodong Zhang, Dongxiang Liu, Chuanshu Huang, Haishan Huang

BMC Cancer. 2023; 23: 898. Published online 2023 Sep 23. doi: 10.1186/s12885-023-11403-2

PMCID:: PMC10518100

Abstract Article PDF–10M

Select item 1049982119.

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets

Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, Celestine N. Chi, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson

Nat Commun. 2023; 14: 5636. Published online 2023 Sep 13. doi: 10.1038/s41467-023-41312-8

PMCID:: PMC10499821

Abstract Article PDF–2.6M

Select item 1044091620.

P300/SP1 complex mediating elevated METTL1 regulates CDK14 mRNA stability via internal m7G modification in CRPC

Mingpeng Zhang, Duo Kan, Boya Zhang, Xueqiao Chen, Chun Wang, Songmao Chen, Wenlong Gao, Zhao Yang, Yang Li, Yutong Chen, Shimiao Zhu, Simeng Wen, Yuanjie Niu, Zhiqun Shang

J Exp Clin Cancer Res. 2023; 42: 215. Published online 2023 Aug 21. doi: 10.1186/s13046-023-02777-z