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Select item 113085701.

TNKS1BP1 mediates AECII senescence and radiation induced lung injury through suppressing EEF2 degradation

Jiaojiao Zhu, Xingkun Ao, Yuhao Liu, Shenghui Zhou, Yifan Hou, Ziyan Yan, Lin Zhou, Huixi Chen, Ping Wang, Xinxin Liang, Dafei Xie, Shanshan Gao, Ping-Kun Zhou, Yongqing Gu

Respir Res. 2024; 25: 299. Published online 2024 Aug 7. doi: 10.1186/s12931-024-02914-y

PMCID:: PMC11308570

Abstract Article PDF–2.6M

Select item 111615122.

Protein translation rate determines neocortical neuron fate

Ekaterina Borisova, Andrew G. Newman, Marta Couce Iglesias, Rike Dannenberg, Theres Schaub, Bo Qin, Alexandra Rusanova, Marisa Brockmann, Janina Koch, Marieatou Daniels, Paul Turko, Olaf Jahn, David R. Kaplan, Marta Rosário, Takao Iwawaki, Christian M. T. Spahn, Christian Rosenmund, David Meierhofer, Matthew L. Kraushar, Victor Tarabykin, Mateusz C. Ambrozkiewicz

Nat Commun. 2024; 15: 4879. Published online 2024 Jun 7. doi: 10.1038/s41467-024-49198-w

PMCID:: PMC11161512

Abstract Article PDF–17M

Select item 110531693.

Diphthamide deficiency promotes association of eEF2 with p53 to induce p21 expression and neural crest defects

Yu Shi, Daochao Huang, Cui Song, Ruixue Cao, Zhao Wang, Dan Wang, Li Zhao, Xiaolu Xu, Congyu Lu, Feng Xiong, Haowen Zhao, Shuxiang Li, Quansheng Zhou, Shuyue Luo, Dongjie Hu, Yun Zhang, Cui Wang, Yiping Shen, Weiting Su, Yili Wu, Karl Schmitz, Shuo Wei, Weihong Song

Nat Commun. 2024; 15: 3301. Published online 2024 Apr 26. doi: 10.1038/s41467-024-47670-1

PMCID:: PMC11053169

Abstract Article PDF–5.8M

Select item 107115664.

The translational oscillation in oocyte and early embryo development

Rajan Iyyappan, Daria Aleshkina, Hao Ming, Michal Dvoran, Kianoush Kakavand, Denisa Jansova, Edgar del Llano, Lenka Gahurova, Alexander W Bruce, Tomas Masek, Martin Pospisek, Filip Horvat, Michal Kubelka, Zongliang Jiang, Andrej Susor

Nucleic Acids Res. 2023 Dec 11; 51(22): 12076–12091. Published online 2023 Nov 10. doi: 10.1093/nar/gkad996

PMCID:: PMC10711566

Abstract Article PDF–2.3M

Select item 104644115.

Interaction of lncRNA Gm2044 and EEF2 promotes estradiol synthesis in ovarian follicular granulosa cells

Ke Hu, Chen Wang, Yifan Xu, Fan Li, Xuefeng Han, Chuanwang Song, Meng Liang

J Ovarian Res. 2023; 16: 171. Published online 2023 Aug 23. doi: 10.1186/s13048-023-01232-z

Correction in:: J Ovarian Res. 2023; 16: 199.

PMCID:: PMC10464411

Abstract Article PDF–3.2M

Select item 103078526.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 102409987.

PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805

Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang

Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558

PMCID:: PMC10240998

Abstract Article PDF–4.4M

Select item 96038608.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95358079.

eEF2 in the prefrontal cortex promotes excitatory synaptic transmission and social novelty behavior

Xuanyue Ma, Liuren Li, Ziming Li, Zhengyi Huang, Yaorong Yang, Peng Liu, Daji Guo, Yueyao Li, Tianying Wu, Ruixiang Luo, Junyu Xu, Wen‐Cai Ye, Bin Jiang, Lei Shi

EMBO Rep. 2022 Oct; 23(10): e54543. Published online 2022 Aug 22. doi: 10.15252/embr.202154543

PMCID:: PMC9535807

Abstract Article PDF–3.8M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 928970911.

TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis

Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen

EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777

PMCID:: PMC9289709

Abstract Article PDF–2.3M

Select item 928323212.

Amyloid beta induces Fmr1‐dependent translational suppression and hyposynchrony of neural activity via phosphorylation of eIF2α and eEF2

Simon Lizarazo, Yeeun Yook, Nien‐Pei Tsai

J Cell Physiol. 2022 Jul; 237(7): 2929–2942. Published online 2022 Apr 17. doi: 10.1002/jcp.30754

PMCID:: PMC9283232

Abstract Article PDF–4.0M

Select item 861097413.

Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation

Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin

Sci Rep. 2021; 11: 22745. Published online 2021 Nov 23. doi: 10.1038/s41598-021-02218-x

PMCID:: PMC8610974

Abstract Article PDF–2.5M

Select item 844227714.

The phosphorylation status of eukaryotic elongation factor-2 indicates neural activity in the brain

Sang Ho Yoon, Woo Seok Song, Sung Pyo Oh, Young Sook Kim, Myoung-Hwan Kim

Mol Brain. 2021; 14: 142. Published online 2021 Sep 15. doi: 10.1186/s13041-021-00852-0

PMCID:: PMC8442277

Abstract Article PDF–2.1M

Select item 831323915.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 826661716.

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins

Benjamin Lang, Jae-Seong Yang, Mireia Garriga-Canut, Silvia Speroni, Moritz Aschern, Maria Gili, Tobias Hoffmann, Gian Gaetano Tartaglia, Sebastian P Maurer

Nucleic Acids Res. 2021 Jul 9; 49(12): 6702–6721. Published online 2021 Jun 16. doi: 10.1093/nar/gkab490

PMCID:: PMC8266617

Abstract Article PDF–4.0M

Select item 794825717.

Repression of eEF2 kinase improves deficits in novel object recognition memory in aged mice.

Saahj Gosrani, Hannah Jester, Xueyan Zhou, Alexey Ryazanov, Tao Ma

Neurobiol Aging. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Neurobiol Aging. 2020 Nov; 95: 154–160. Published online 2020 Jul 25. doi: 10.1016/j.neurobiolaging.2020.07.016

PMCID:: PMC7948257

Abstract Article PDF–620K

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 785213719.

Fluoxetine regulates eEF2 activity (phosphorylation) via HDAC1 inhibitory mechanism in an LPS-induced mouse model of depression

Weifen Li, Tahir Ali, Chengyou Zheng, Zizhen Liu, Kaiwu He, Fawad Ali Shah, Qingguo Ren, Shafiq Ur Rahman, Ningning Li, Zhi-Jian Yu, Shupeng Li

J Neuroinflammation. 2021; 18: 38. Published online 2021 Feb 1. doi: 10.1186/s12974-021-02091-5

Correction in:: J Neuroinflammation. 2022; 19: 317.

PMCID:: PMC7852137

Abstract Article PDF–3.5M

Select item 751195320.

Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes

Maxim V. Gerashchenko, Mikhail V. Nesterchuk, Elena M. Smekalova, Joao A. Paulo, Piotr S. Kowalski, Kseniya A. Akulich, Roman Bogorad, Sergey E. Dmitriev, Steven Gygi, Timofei Zatsepin, Daniel G. Anderson, Vadim N. Gladyshev, Victor E. Koteliansky

Sci Rep. 2020; 10: 15473. Published online 2020 Sep 23. doi: 10.1038/s41598-020-72399-4

PMCID:: PMC7511953

Abstract Article PDF–7.4M

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