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Items: 1 to 20 of 25

1.
USP13 promotes deubiquitination of ZHX2 and tumorigenesis in kidney cancer
Haibiao Xie, Jin Zhou, Xijuan Liu, Yawei Xu, Austin J. Hepperla, Jeremy M. Simon, Tao Wang, Hongwei Yao, Chengheng Liao, Albert S. Baldwin, Kan Gong, Qing Zhang
Proc Natl Acad Sci U S A. 2022 Sep 6; 119(36): e2119854119. Published online 2022 Aug 29. doi: 10.1073/pnas.2119854119
PMCID:
PMC9457248
AbstractArticlePDF–3.1M
2.
Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis
Kamini Kaushal, Eun-Jung Kim, Apoorvi Tyagi, Janardhan Keshav Karapurkar, Saba Haq, Han-Sung Jung, Kye-Seong Kim, Suresh Ramakrishna
Cell Death Differ. 2022 Sep; 29(9): 1689–1704. Published online 2022 Mar 10. doi: 10.1038/s41418-022-00956-7
PMCID:
PMC9433428
AbstractArticlePDF–13M
3.
Oncogenic Activity of Glucocorticoid Receptor β Is Controlled by Ubiquitination-Dependent Interaction with USP49 in Glioblastoma Cells
Yaling Hu, Yingdi Jiang, Zhenhao Zhang, Jingjing Wang, Bo Zhang, Lingli Gong, Li Ji, Zhening Pu, Xusheng Yang, Jian Zou, Ying Yin
Mol Cancer Res. 2022 Jan 1; 20(1): 92–101. Published online 2021 Oct 5. doi: 10.1158/1541-7786.MCR-20-1068
PMCID:
PMC9398152
AbstractArticlePDF–1.2M
4.
USP49-Mediated Histone H2B Deubiquitination Regulates HCT116 Cell Proliferation through MDM2-p53 Axis
Lei Shi, Xiangyu Shen, Yuan Shen
Mol Cell Biol. 2022 Mar; 42(3): e00434-21. Prepublished online 2022 Jan 24. Published online 2022 Mar 17. doi: 10.1128/mcb.00434-21
Correction in:
Mol Cell Biol. 2022 Jun; 42(6): e00139-22.
PMCID:
PMC8929337
AbstractArticlePDF–2.3M
5.
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation
Linhui Wu, Ke Yu, Kai Chen, Xuelian Zhu, Zheng Yang, Qi Wang, Junjie Gao, Yingying Wang, Tong Cao, Hui Xu, Xueshan Pan, Lixia Wang, Jun Xia, Yuyun Li, Zhiwei Peter Wang, Jia Ma
Cell Death Dis. 2022 Mar; 13(3): 231. Published online 2022 Mar 12. doi: 10.1038/s41419-022-04675-2
PMCID:
PMC8918322
AbstractArticlePDF–5.2M
6.
CCAT1/FABP5 promotes tumour progression through mediating fatty acid metabolism and stabilizing PI3K/AKT/mTOR signalling in lung adenocarcinoma
Jing Chen, Yaser Alduais, Kai Zhang, Xiaoli Zhu, Baoan Chen
J Cell Mol Med. 2021 Oct; 25(19): 9199–9213. Published online 2021 Aug 25. doi: 10.1111/jcmm.16815
PMCID:
PMC8500980
AbstractArticlePDF–2.7M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
The long non‐coding RNA HLNC1 potentiates hepatocellular carcinoma progression via interaction with USP49
Xinye Qian, Shitong Li, Zhoujing Yang, Jun Zhang
J Clin Lab Anal. 2020 Nov; 34(11): e23462. Published online 2020 Jul 21. doi: 10.1002/jcla.23462
PMCID:
PMC7676201
AbstractArticlePDF–1.4M
9.
APC/C-dependent control of gene expression and cell identity
Eugene Oh, Kevin G. Mark, Annamaria Mocciaro, Edmond R. Watson, J. Rajan Prabu, Denny D. Cha, Martin Kampmann, Nathan Gamarra, Coral Y. Zhou, Michael Rape
Nature. Author manuscript; available in PMC 2020 Aug 19.
Published in final edited form as: Nature. 2020 Mar; 579(7797): 136–140. Published online 2020 Feb 19. doi: 10.1038/s41586-020-2034-1
PMCID:
PMC7402266
AbstractArticlePDF–5.3M
10.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
11.
USP49 potently stabilizes APOBEC3G protein by removing ubiquitin and inhibits HIV-1 replication
Ting Pan, Zheng Song, Liyang Wu, Guangyan Liu, Xiancai Ma, Zhilin Peng, Mo Zhou, Liting Liang, Bingfeng Liu, Jun Liu, Junsong Zhang, Xuanhong Zhang, Ryan Huang, Jiacong Zhao, Yonghong Li, Xuemei Ling, Yuewen Luo, Xiaoping Tang, Weiping Cai, Kai Deng, Linghua Li, Hui Zhang
eLife. 2019; 8: e48318. Published online 2019 Aug 9. doi: 10.7554/eLife.48318
PMCID:
PMC6701944
AbstractArticlePDF–3.5M
12.
USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA
Liya Ye, Qiang Zhang, Tianzi Liuyu, Zhigao Xu, Meng-Xin Zhang, Min-Hua Luo, Wen-Bo Zeng, Qiyun Zhu, Dandan Lin, Bo Zhong
PLoS Pathog. 2019 Apr; 15(4): e1007680. Published online 2019 Apr 3. doi: 10.1371/journal.ppat.1007680
PMCID:
PMC6464240
AbstractArticlePDF–3.1M
13.
Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin
Jongchan Kim, Fatemeh Alavi Naini, Yutong Sun, Li Ma
Am J Cancer Res. 2018; 8(9): 1823–1836. Published online 2018 Sep 1.
PMCID:
PMC6176183
AbstractArticlePDF–3.1M
14.
USP49 participates in the DNA damage response by forming a positive feedback loop with p53
Rongfu Tu, Wenqian Kang, Xuefei Yang, Qi Zhang, Xiaoyu Xie, Wenbin Liu, Jinxiang Zhang, Xiao-Dong Zhang, Hui Wang, Run-Lei Du
Cell Death Dis. 2018 May; 9(5): 553. Published online 2018 May 10. doi: 10.1038/s41419-018-0475-3
PMCID:
PMC5945681
AbstractArticlePDF–1.7M
15.
ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer
Peijing Zhang, Zhenna Xiao, Shouyu Wang, Mutian Zhang, Yongkun Wei, Qinglei Hang, Jongchan Kim, Fan Yao, Cristian Rodriguez-Aguayo, Baochau N. Ton, Minjung Lee, Yumeng Wang, Zhicheng Zhou, Liyong Zeng, Xiaoyu Hu, Sarah E. Lawhon, Ashley N. Siverly, Xiaohua Su, Jia Li, Xiaoping Xie, Xuhong Cheng, Liang-Chiu Liu, Hui-Wen Chang, Shu-Fen Chiang, Gabriel Lopez-Berestein, Anil K. Sood, Junjie Chen, M. James You, Shao-Cong Sun, Han Liang, Yun Huang, Xianbin Yang, Deqiang Sun, Yutong Sun, Mien-Chie Hung, Li Ma
Cell Rep. Author manuscript; available in PMC 2018 May 3.
Published in final edited form as: Cell Rep. 2018 Apr 17; 23(3): 823–837. doi: 10.1016/j.celrep.2018.03.078
PMCID:
PMC5933875
AbstractArticlePDF–2.0M
16.
USP49 negatively regulates tumorigenesis and chemoresistance through FKBP51‐AKT signaling
Kuntian Luo, Yunhui Li, Yujiao Yin, Lei Li, Chenming Wu, Yuping Chen, Somaira Nowsheen, Qi Hu, Lizhi Zhang, Zhenkun Lou, Jian Yuan
EMBO J. 2017 May 15; 36(10): 1434–1446. Published online 2017 Mar 31. doi: 10.15252/embj.201695669
PMCID:
PMC5430216
AbstractArticlePDF–1.2M
17.
USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA
Man Zhang, Meng-Xin Zhang, Qiang Zhang, Gao-Feng Zhu, Lei Yuan, Dong-Er Zhang, Qiyun Zhu, Jing Yao, Hong-Bing Shu, Bo Zhong
Cell Res. 2016 Dec; 26(12): 1302–1319. Published online 2016 Nov 1. doi: 10.1038/cr.2016.125
PMCID:
PMC5143414
AbstractArticlePDF–5.5M
18.
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways
Mikko Taipale, George Tucker, Jian Peng, Irina Krykbaeva, Zhen-Yuan Lin, Brett Larsen, Hyungwon Choi, Bonnie Berger, Anne-Claude Gingras, Susan Lindquist
Cell. Author manuscript; available in PMC 2015 Jul 17.
Published in final edited form as: Cell. 2014 Jul 17; 158(2): 434–448. doi: 10.1016/j.cell.2014.05.039
PMCID:
PMC4104544
AbstractArticlePDF–3.2M
19.
USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing
Zhuo Zhang, Amanda Jones, Heui-Yun Joo, Dewang Zhou, Ying Cao, Shaoxia Chen, Hediye Erdjument-Bromage, Matthew Renfrow, Hang He, Paul Tempst, Tim M. Townes, Keith E. Giles, Ligeng Ma, Hengbin Wang
Genes Dev. 2013 Jul 15; 27(14): 1581–1595. doi: 10.1101/gad.211037.112
PMCID:
PMC3731547
AbstractArticlePDF–3.3M
20.
GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children
Jin Li, Joseph T. Glessner, Haitao Zhang, Cuiping Hou, Zhi Wei, Jonathan P. Bradfield, Frank D. Mentch, Yiran Guo, Cecilia Kim, Qianghua Xia, Rosetta M. Chiavacci, Kelly A. Thomas, Haijun Qiu, Struan F.A. Grant, Susan L. Furth, Hakon Hakonarson, Patrick M.A. Sleiman
Hum Mol Genet. 2013 Apr 1; 22(7): 1457–1464. Published online 2012 Dec 20. doi: 10.1093/hmg/dds534
PMCID:
PMC3657475
AbstractArticlePDF–147K

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