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Items: 1 to 20 of 151

1.
Construction of a nomogram for predicting HNSCC distant metastasis and identification of EIF5A as a hub gene
Xin Chen, Ying Zhang, Sheng Chen, Yan Yang, Guowen Sun, Peng Pan
Sci Rep. 2024; 14: 13367. Published online 2024 Jun 11. doi: 10.1038/s41598-024-64197-z
PMCID:
PMC11166653
AbstractArticlePDF–9.1M
2.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
3.
AMD1 promotes breast cancer aggressiveness via a spermidine-eIF5A hypusination-TCF4 axis
Ruocen Liao, Xingyu Chen, Qianhua Cao, Longchang Bai, Chenglong Ma, Zhijun Dai, Chenfang Dong
Breast Cancer Res. 2024; 26: 70. Published online 2024 Apr 23. doi: 10.1186/s13058-024-01825-6
PMCID:
PMC11040792
AbstractArticlePDF–8.2M
4.
Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly
Emilie Murigneux, Laurent Softic, Corentin Aubé, Carmen Grandi, Delphine Judith, Johanna Bruce, Morgane Le Gall, François Guillonneau, Alain Schmitt, Vincent Parissi, Clarisse Berlioz-Torrent, Laurent Meertens, Maike M. K. Hansen, Sarah Gallois-Montbrun
Nat Commun. 2024; 15: 640. Published online 2024 Jan 20. doi: 10.1038/s41467-024-44958-0
PMCID:
PMC10799903
AbstractArticlePDF–25M
5.
SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells
Rocío Seoane, Tomás Lama-Díaz, Antonia María Romero, Ahmed El Motiam, Arantxa Martínez-Férriz, Santiago Vidal, Yanis H. Bouzaher, María Blanquer, Rocío M. Tolosa, Juan Castillo Mewa, Manuel S. Rodríguez, Adolfo García-Sastre, Dimitris Xirodimas, James D. Sutherland, Rosa Barrio, Paula Alepuz, Miguel G. Blanco, Rosa Farràs, Carmen Rivas
Cell Mol Biol Lett. 2024; 29: 15. Published online 2024 Jan 16. doi: 10.1186/s11658-024-00533-5
PMCID:
PMC10790418
AbstractArticlePDF–3.6M
6.
Targeted inhibition of eIF5Ahpu suppresses tumor growth and polarization of M2-like tumor-associated macrophages in oral cancer
Jincheng Zeng, Ziyu Ye, Shihong Shi, Yanfang Liang, Qingyu Meng, Qunzhou Zhang, Anh D. Le
Cell Death Dis. 2023 Aug; 14(8): 579. Published online 2023 Aug 31. doi: 10.1038/s41419-023-06109-z
PMCID:
PMC10471704
AbstractArticlePDF–7.7M
7.
Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry
Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang
Anal Chem. Author manuscript; available in PMC 2023 Jun 21.
Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986
PMCID:
PMC10284117
AbstractArticlePDF–2.5M
8.
Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis
Leah R. Padgett, Mollie R. Shinkle, Spencer Rosario, Tracy Murray Stewart, Jackson R. Foley, Robert A. Casero, Jr., Myung Hee Park, Wendy K. Chung, Teresa L. Mastracci
HGG Adv. 2023 Jul 13; 4(3): 100206. Published online 2023 May 18. doi: 10.1016/j.xhgg.2023.100206
PMCID:
PMC10275725
AbstractArticlePDF–3.6M
9.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
10.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
11.
Comparison of Human Eukaryotic Translation Initiation Factors 5A1 and 5AL1: Identification of Amino Acid Residues Important for EIF5A1 Lysine 50 Hypusination and Its Protein Stability
Yu-Yao Wu, Gao-Qi Wu, Na-Li Cai, Yan-Ming Xu, Andy T. Y. Lau
Int J Mol Sci. 2023 Apr; 24(7): 6067. Published online 2023 Mar 23. doi: 10.3390/ijms24076067
PMCID:
PMC10093921
AbstractArticlePDF–3.3M
12.
Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders
Elżbieta Wątor, Piotr Wilk, Artur Biela, Michał Rawski, Krzysztof M. Zak, Wieland Steinchen, Gert Bange, Sebastian Glatt, Przemysław Grudnik
Nat Commun. 2023; 14: 1698. Published online 2023 Mar 27. doi: 10.1038/s41467-023-37305-2
PMCID:
PMC10042821
AbstractArticlePDF–7.9M
13.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
14.
Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2
Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang
J Virol. 2023 Feb; 97(2): e01611-22. Published online 2023 Feb 13. doi: 10.1128/jvi.01611-22
PMCID:
PMC9972945
AbstractArticlePDF–3.0M
15.
Renal Ischemia Tolerance Mediated by eIF5A Hypusination Inhibition Is Regulated by a Specific Modulation of the Endoplasmic Reticulum Stress
Nicolas Melis, Isabelle Rubera, Sebastien Giraud, Marc Cougnon, Christophe Duranton, Mallorie Poet, Gisèle Jarretou, Raphaël Thuillier, Laurent Counillon, Thierry Hauet, Luc Pellerin, Michel Tauc, Didier F. Pisani
Cells. 2023 Feb; 12(3): 409. Published online 2023 Jan 25. doi: 10.3390/cells12030409
PMCID:
PMC9913814
AbstractArticlePDF–3.6M
16.
The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers
Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy
eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676
PMCID:
PMC9708086
AbstractArticlePDF–8.5M
17.
A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation
Yulemi Gonzalez Quesada, Luc DesGroseillers
Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588
PMCID:
PMC9569955
AbstractArticlePDF–2.1M
18.
Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition
Ilaria Iacobucci, Vittoria Monaco, Luisa Canè, Francesca Bibbò, Valentina Cioffi, Flora Cozzolino, Alfredo Guarino, Massimo Zollo, Maria Monti
Front Mol Biosci. 2022; 9: 975570. Published online 2022 Sep 26. doi: 10.3389/fmolb.2022.975570
PMCID:
PMC9550266
AbstractArticlePDF–2.5M
19.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy
Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui
Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y
PMCID:
PMC9440653
AbstractArticlePDF–2.9M
20.
Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling
Yansheng Zhai, Xiaoyan Huang, Keren Zhang, Yuchen Huang, Yanlong Jiang, Jingwei Cui, Zhe Zhang, Cookson K. C. Chiu, Weiye Zhong, Gang Li
Nat Commun. 2022; 13: 4906. Published online 2022 Aug 20. doi: 10.1038/s41467-022-32689-z
PMCID:
PMC9392063
AbstractArticlePDF–2.0M

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