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Items: 18

1.
Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform
Dirk H Siepe, Lukas T Henneberg, Steven C Wilson, Gaelen T Hess, Michael C Bassik, Kai Zinn, K Christopher Garcia
eLife. 2022; 11: e81398. Published online 2022 Sep 30. doi: 10.7554/eLife.81398
PMCID:
PMC9578707
AbstractArticlePDF–3.3M
2.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
AbstractArticlePDF–3.0M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
TAFA2 Induces Skeletal (Stromal) Stem Cell Migration Through Activation of Rac1‐p38 Signaling
Abbas Jafari, Adiba Isa, Li Chen, Nicholas Ditzel, Walid Zaher, Linda Harkness, Hans E. Johnsen, Basem M. Abdallah, Christian Clausen, Moustapha Kassem
Stem Cells. 2019 Mar; 37(3): 407–416. Published online 2018 Dec 17. doi: 10.1002/stem.2955
PMCID:
PMC7379704
AbstractArticlePDF–3.3M
5.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
6.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
7.
Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci
Geoffrey A. Walford, Stefan Gustafsson, Denis Rybin, Alena Stančáková, Han Chen, Ching-Ti Liu, Jaeyoung Hong, Richard A. Jensen, Ken Rice, Andrew P. Morris, Reedik Mägi, Anke Tönjes, Inga Prokopenko, Marcus E. Kleber, Graciela Delgado, Günther Silbernagel, Anne U. Jackson, Emil V. Appel, Niels Grarup, Joshua P. Lewis, May E. Montasser, Claes Landenvall, Harald Staiger, Jian’an Luan, Timothy M. Frayling, Michael N. Weedon, Weijia Xie, Sonsoles Morcillo, María Teresa Martínez-Larrad, Mary L. Biggs, Yii-Der Ida Chen, Arturo Corbaton-Anchuelo, Kristine Færch, Juan Miguel Gómez-Zumaquero, Mark O. Goodarzi, Jorge R. Kizer, Heikki A. Koistinen, Aaron Leong, Lars Lind, Cecilia Lindgren, Fausto Machicao, Alisa K. Manning, Gracia María Martín-Núñez, Gemma Rojo-Martínez, Jerome I. Rotter, David S. Siscovick, Joseph M. Zmuda, Zhongyang Zhang, Manuel Serrano-Rios, Ulf Smith, Federico Soriguer, Torben Hansen, Torben J. Jørgensen, Allan Linnenberg, Oluf Pedersen, Mark Walker, Claudia Langenberg, Robert A. Scott, Nicholas J. Wareham, Andreas Fritsche, Hans-Ulrich Häring, Norbert Stefan, Leif Groop, Jeff R. O’Connell, Michael Boehnke, Richard N. Bergman, Francis S. Collins, Karen L. Mohlke, Jaakko Tuomilehto, Winfried März, Peter Kovacs, Michael Stumvoll, Bruce M. Psaty, Johanna Kuusisto, Markku Laakso, James B. Meigs, Josée Dupuis, Erik Ingelsson, Jose C. Florez
Diabetes. 2016 Oct; 65(10): 3200–3211. Published online 2016 Jul 14. doi: 10.2337/db16-0199
PMCID:
PMC5033262
AbstractArticlePDF–1.0M
8.
Hypertrophy‐Associated Polymorphisms Ascertained in a Founder Cohort Applied to Heart Failure Risk and Mortality
Afshin Parsa, Yen‐Pei C. Chang, Reagan J. Kelly, Mary C. Corretti, Kathleen A. Ryan, Shawn W. Robinson, Stephen S. Gottlieb, Sharon L.R. Kardia, Alan R. Shuldiner, Stephen B. Liggett
Clin Transl Sci. 2011 Feb; 4(1): 17–23. Published online 2011 Feb 23. doi: 10.1111/j.1752-8062.2010.00251.x
PMCID:
PMC4373555
AbstractArticlePDF–971K
9.
Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype
Manuel A. R. Ferreira, Melanie C. Matheson, Clara S. Tang, Raquel Granell, Wei Ang, Jennie Hui, Amy K. Kiefer, David L. Duffy, Svetlana Baltic, Patrick Danoy, Minh Bui, Loren Price, Peter D. Sly, Nicholas Eriksson, Pamela A. Madden, Michael J. Abramson, Patrick G. Holt, Andrew C. Heath, Michael Hunter, Bill Musk, Colin F. Robertson, Peter Le Souëf, Grant W. Montgomery, A. John Henderson, Joyce Y. Tung, Shyamali C. Dharmage, Matthew A. Brown, Alan James, Philip J. Thompson, Craig Pennell, Nicholas G. Martin, David M. Evans, David A. Hinds, John L. Hopper, the Australian Asthma Genetics Consortium Collaborators
J Allergy Clin Immunol. Author manuscript; available in PMC 2015 Jun 1.
Published in final edited form as: J Allergy Clin Immunol. 2014 Jun; 133(6): 1564–1571. Published online 2013 Dec 31. doi: 10.1016/j.jaci.2013.10.030
PMCID:
PMC4280183
AbstractArticlePDF–350K
10.
Admixture Mapping Identifies a Quantitative Trait Locus Associated with FEV1/FVC in the COPDGene Study
Margaret M. Parker, Marilyn G. Foreman, Haley J. Abel, Rasika A. Mathias, Jacqueline B. Hetmanksi, James D. Crapo, Edwin K. Silverman, Terri H. Beaty, COPDGene Investigators
Genet Epidemiol. Author manuscript; available in PMC 2015 Nov 1.
Published in final edited form as: Genet Epidemiol. 2014 Nov; 38(7): 652–659. Published online 2014 Aug 11. doi: 10.1002/gepi.21847
PMCID:
PMC4190160
AbstractArticlePDF–350K
11.
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis
Michael H. Cho, Merry-Lynn N. McDonald, Xiaobo Zhou, Manuel Mattheisen, Peter J. Castaldi, Craig P. Hersh, Dawn L. DeMeo, Jody S. Sylvia, John Ziniti, Nan M. Laird, Christoph Lange, Augusto A. Litonjua, David Sparrow, Richard Casaburi, R. Graham Barr, Elizabeth A. Regan, Barry J. Make, John E. Hokanson, Sharon Lutz, Tanda Murray, Homayoon Farzadegan, Jacqueline B. Hetmanski, Ruth Tal-Singer, David A. Lomas, Per Bakke, Amund Gulsvik, James D. Crapo, Edwin K. Silverman, Terri H. Beaty, on behalf of the NETT Genetics, ICGN, ECLIPSE, and COPDGene Investigators
Lancet Respir Med. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: Lancet Respir Med. 2014 Mar; 2(3): 214–225. Published online 2014 Feb 7. doi: 10.1016/S2213-2600(14)70002-5
PMCID:
PMC4176924
AbstractArticlePDF–976K
12.
Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384
Paul D. Leger, Daniel H. Johnson, Gregory K. Robbins, Robert W. Shafer, David B. Clifford, Jun Li, Paul J. McLaren, David W. Haas
J Neurovirol. 2014; 20(3): 304–308. Published online 2014 Feb 20. doi: 10.1007/s13365-014-0235-9
PMCID:
PMC4114519
AbstractArticlePDF–233K
13.
Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population
Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte
PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954
PMCID:
PMC3522587
AbstractArticlePDF–130K
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score
Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl
Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159
Correction in:
Mol Med. 2012; 18(1): 729.
PMCID:
PMC2896464
AbstractArticlePDF–2.4M
16.
Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res. 2006 Jan; 16(1): 55–65. doi: 10.1101/gr.4039406
PMCID:
PMC1356129
AbstractArticlePDF–438K
17.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
18.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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