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Items: 1 to 20 of 27

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
GPSM1 in POMC neurons impairs brown adipose tissue thermogenesis and provokes diet-induced obesity
Mengyang Tang, Yi Zhang, Rong Zhang, Yuemei Zhang, Jiangfei Zheng, Daixi Wang, Xinyu Wang, Jing Yan, Cheng Hu
Mol Metab. 2024 Jan; 79: 101839. Published online 2023 Nov 17. doi: 10.1016/j.molmet.2023.101839
PMCID:
PMC10698273
AbstractArticlePDF–4.9M
3.
AGS3 antagonizes LGN to balance oriented cell divisions and cell fate choices in mammalian epidermis
Carlos P Descovich, Kendall J Lough, Akankshya Jena, Jessica J Wu, Jina Yom, Danielle C Spitzer, Manuela Uppalapati, Katarzyna M Kedziora, Scott E Williams
eLife. 2023; 12: e80403. Published online 2023 Apr 5. doi: 10.7554/eLife.80403
PMCID:
PMC10115442
AbstractArticlePDF–5.5M
4.
GPSM1 impairs metabolic homeostasis by controlling a pro-inflammatory pathway in macrophages
Jing Yan, Yuemei Zhang, Hairong Yu, Yicen Zong, Daixi Wang, Jiangfei Zheng, Li Jin, Xiangtian Yu, Caizhi Liu, Yi Zhang, Feng Jiang, Rong Zhang, Xiangnan Fang, Ting Xu, Mingyu Li, Jianzhong Di, Yan Lu, Xinran Ma, Jian Zhang, Weiping Jia, Cheng Hu
Nat Commun. 2022; 13: 7260. Published online 2022 Nov 25. doi: 10.1038/s41467-022-34998-9
PMCID:
PMC9700814
AbstractArticlePDF–6.3M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton
Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622
PMCID:
PMC8098814
AbstractArticlePDF–7.7M
7.
Gαi2 signaling regulates inflammasome priming and cytokine production by biasing macrophage phenotype determination
Ali Vural, Neel R. Nabar, Il-Young Hwang, Silke Sohn, Chung Park, Mikael C. I. Karlsson, Joe B. Blumer, John H. Kehrl
J Immunol. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: J Immunol. 2019 Mar 1; 202(5): 1510–1520. Published online 2019 Jan 25. doi: 10.4049/jimmunol.1801145
PMCID:
PMC6382563
AbstractArticlePDF–1.2M
8.
Loss of the canonical spindle orientation function in the Pins/LGN homolog AGS3
Mehdi Saadaoui, Daijiro Konno, Karine Loulier, Rosette Goiame, Vaibhav Jadhav, Marina Mapelli, Fumio Matsuzaki, Xavier Morin
EMBO Rep. 2017 Sep; 18(9): 1509–1520. Published online 2017 Jul 6. doi: 10.15252/embr.201643048
PMCID:
PMC5579374
AbstractArticlePDF–1.8M
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
Activator of G-protein Signaling 3 (AGS3)-induced lysosomal biogenesis limits macrophage intracellular bacterial infection
Ali Vural, Souhaila Al Khodor, Gordon Y.C. Cheung, Chong-Shan Shi, Lalitha Srinivasan, Travis J. McQuiston, Il-Young Hwang, Anthony J. Yeh, Joe B. Blumer, Volker Briken, Peter R. Williamson, Michael Otto, Iain D.C. Fraser, John H. Kehrl
J Immunol. Author manuscript; available in PMC 2017 Jan 15.
Published in final edited form as: J Immunol. 2016 Jan 15; 196(2): 846–856. Published online 2015 Dec 14. doi: 10.4049/jimmunol.1501595
PMCID:
PMC4811337
AbstractArticlePDF–1.9M
11.
Defective Chemokine Signal Integration in Leukocytes Lacking Activator of G Protein Signaling 3 (AGS3)
Melissa Branham-O'Connor, William G. Robichaux, III, Xian-Kui Zhang, Hyeseon Cho, John H. Kehrl, Stephen M. Lanier, Joe B. Blumer
J Biol Chem. 2014 Apr 11; 289(15): 10738–10747. Published online 2014 Feb 26. doi: 10.1074/jbc.M113.515031
PMCID:
PMC4036190
AbstractArticlePDF–1.2M
12.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
13.
G-protein-coupled receptor kinase-6 interacts with Activator of G-protein signaling-3 to regulate CXCR2-mediated cellular functions
Vandana Singh, Sandeep K. Raghuwanshi, Nikia Smith, Elizabeth J. Rivers, Ricardo M. Richardson
J Immunol. Author manuscript; available in PMC 2015 Mar 1.
Published in final edited form as: J Immunol. 2014 Mar 1; 192(5): 2186–2194. Published online 2014 Feb 7. doi: 10.4049/jimmunol.1301875
PMCID:
PMC3950967
AbstractArticlePDF–1.4M
14.
Normal Autophagic Activity in Macrophages from Mice Lacking Gαi3, AGS3, or RGS19
Ali Vural, Travis J. McQuiston, Joe B. Blumer, Chung Park, Il-Young Hwang, Yolanda Williams-Bey, Chong-Shan Shi, Dzwokai Zach Ma, John H. Kehrl
PLoS One. 2013; 8(11): e81886. Published online 2013 Nov 28. doi: 10.1371/journal.pone.0081886
PMCID:
PMC3842979
AbstractArticlePDF–1.5M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease
Michelle Kwon, Tengis S. Pavlov, Kandai Nozu, Shauna A. Rasmussen, Daria V. Ilatovskaya, Alexandra Lerch-Gaggl, Lauren M. North, Hyunho Kim, Feng Qian, William E. Sweeney, Jr., Ellis D. Avner, Joe B. Blumer, Alexander Staruschenko, Frank Park
Proc Natl Acad Sci U S A. 2012 Dec 26; 109(52): 21462–21467. Published online 2012 Dec 10. doi: 10.1073/pnas.1216830110
PMCID:
PMC3535663
AbstractArticlePDF–680K
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents
Kevin R. Regner, Kandai Nozu, Stephen M. Lanier, Joe B. Blumer, Ellis D. Avner, William E. Sweeney, Jr, Frank Park
FASEB J. 2011 Jun; 25(6): 1844–1855. doi: 10.1096/fj.10-169797
PMCID:
PMC3101034
AbstractArticle
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives
Owen J Tamplin, Doris Kinzel, Brian J Cox, Christine E Bell, Janet Rossant, Heiko Lickert
BMC Genomics. 2008; 9: 511. Published online 2008 Oct 30. doi: 10.1186/1471-2164-9-511
PMCID:
PMC2605479
AbstractArticlePDF–1.7M

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