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Select item 115013771.

USP4 promotes PTC progression by stabilizing LDHA and activating the MAPK and AKT signaling pathway

Chuanxiang Hu, Wei Zhang, Yongsheng Jia, Jimin Zhao, Qian Chen, Chengfei Hao, Yang Yu

Aging (Albany NY) 2024 Oct 15; 16(19): 12850–12865. Published online 2024 Oct 11. doi: 10.18632/aging.206108

PMCID:: PMC11501377

Abstract Article PDF–9.1M

Select item 114954532.

LncRNA TMPO-AS1 Promotes Triple-Negative Breast Cancer by Sponging miR-383-5p to Trigger the LDHA Axis

Prerna Vats, Jai Singh, Sandeep K. Srivastava, Ashok Kumar, Rajeev Nema

Asian Pac J Cancer Prev. 2024; 25(8): 2929–2944. doi: 10.31557/APJCP.2024.25.8.2929

PMCID:: PMC11495453

Abstract Article PDF–2.6M

Select item 114472563.

Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer

Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y

PMCID:: PMC11447256

Abstract Article PDF–2.8M

Select item 113636454.

Advancements in research on lactate dehydrogenase A in urinary system tumors

Zhiyuan Zhuo, Yu Wang, Yifan Xu

BMC Urol. 2024; 24: 187. Published online 2024 Aug 30. doi: 10.1186/s12894-024-01580-y

PMCID:: PMC11363645

Abstract Article PDF–2.1M

Select item 112969145.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 112721236.

HOXC4 promotes proliferation of pancreatic cancer cells by increasing LDHA-mediated glycolysis

Hao Zhang, Bing Han, She Tian, Yongjun Gong, Liwen Chen, Li Liu

Aging (Albany NY) 2024 Jul 15; 16(13): 11103–11116. Published online 2024 Jul 9. doi: 10.18632/aging.206008

PMCID:: PMC11272123

Abstract Article PDF–2.3M

Select item 112677687.

Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer

Chiara Papulino, Ugo Chianese, Ahmad Ali, Gregorio Favale, Concetta Tuccillo, Fortunato Ciardiello, Annabella Di Mauro, Chiara Mignogna, Gerardo Ferrara, Alfredo Budillon, Wouter Leonard Megchelenbrink, Nunzio Del Gaudio, Mariarosaria Conte, Fabrizio Merciai, Pietro Campiglia, Lucia Altucci, Vincenzo Carafa, Eduardo Sommella, Rosaria Benedetti

J Transl Med. 2024; 22: 676. Published online 2024 Jul 24. doi: 10.1186/s12967-024-05517-9

PMCID:: PMC11267768

Abstract Article PDF–4.9M

Select item 112365638.

TurboID-mediated proximity labeling technologies to identify virus co-receptors

Bo Wang, Fan Yang, Wuqian Wang, Fei Zhao, Xiaofang Sun

Front Cell Infect Microbiol. 2024; 14: 1371837. Published online 2024 Jun 27. doi: 10.3389/fcimb.2024.1371837

PMCID:: PMC11236563

Abstract Article PDF–2.8M

Select item 112099359.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 1119236610.

KCNK1 promotes proliferation and metastasis of breast cancer cells by activating lactate dehydrogenase A (LDHA) and up-regulating H3K18 lactylation

Xiangchan Hou, Jiawei Ouyang, Le Tang, Pan Wu, Xiangying Deng, Qijia Yan, Lei Shi, Songqing Fan, Chunmei Fan, Can Guo, Qianjin Liao, Yong Li, Wei Xiong, Guiyuan Li, Zhaoyang Zeng, Fuyan Wang

PLoS Biol. 2024 Jun; 22(6): e3002666. Published online 2024 Jun 21. doi: 10.1371/journal.pbio.3002666

PMCID:: PMC11192366

Abstract Article PDF–7.6M

Select item 1099027711.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 1091485412.

Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression

Fatima Khan, Yiyun Lin, Heba Ali, Lizhi Pang, Madeline Dunterman, Wen-Hao Hsu, Katie Frenis, R. Grant Rowe, Derek A. Wainwright, Kathleen McCortney, Leah K. Billingham, Jason Miska, Craig Horbinski, Maciej S. Lesniak, Peiwen Chen

Nat Commun. 2024; 15: 1987. Published online 2024 Mar 5. doi: 10.1038/s41467-024-46193-z

PMCID:: PMC10914854

Abstract Article PDF–10M

Select item 1091431113.

Cytoplasmic localization of SETDB1-induced Warburg effect via c-MYC-LDHA axis enhances migration and invasion in breast carcinoma

Wenlin Yang, Yingze Wei, Ting Wang, Ying Xu, Xiaoxia Jin, Hongyan Qian, Shuyun Yang, Song He

Int J Mol Med. 2024 Apr; 53(4): 40. Published online 2024 Feb 28. doi: 10.3892/ijmm.2024.5364

PMCID:: PMC10914311

Abstract Article PDF–9.6M

Select item 1087570914.

LRPPRC promotes glycolysis by stabilising LDHA mRNA and its knockdown plus glutamine inhibitor induces synthetic lethality via m⁶A modification in triple‐negative breast cancer

Yuanhang Yu, Huifang Deng, Wenwen Wang, Shihan Xiao, Renjing Zheng, Lianqiu Lv, Han Wang, Jianying Chen, Bo Zhang

Clin Transl Med. 2024 Feb; 14(2): e1583. Published online 2024 Feb 19. doi: 10.1002/ctm2.1583

PMCID:: PMC10875709

Abstract Article PDF–15M

Select item 1087163415.

Canonical Wnt signaling promotes HSC glycolysis and liver fibrosis through an LDH-A/HIF-1α transcriptional complex

Feixia Wang, Li Chen, Desong Kong, Xiaojin Zhang, Siwei Xia, Baoyu Liang, Yang Li, Ya Zhou, Zili Zhang, Jiangjuan Shao, Shizhong Zheng, Feng Zhang

Hepatology. 2024 Mar; 79(3): 606–623. Published online 2023 Sep 21. doi: 10.1097/HEP.0000000000000569

PMCID:: PMC10871634

Abstract Article PDF–2.0M

Select item 1075973116.

Circ_MAPK9 promotes STAT3 and LDHA expression by silencing miR-642b-3p and affects the progression of hepatocellular carcinoma

Kunyuan Wang, Qianting Lu, Yufeng Luo, Ganxiang Yu, Zhilei Wang, Jiaen Lin, Zhenlin Tan, Yueqiong Lao, Shiming Liu, Hui Yang

Biol Direct. 2024; 19: 4. Published online 2024 Jan 2. doi: 10.1186/s13062-023-00442-1

PMCID:: PMC10759731

Abstract Article PDF–7.6M

Select item 1056587617.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1050265718.

MLF2 Negatively Regulates P53 and Promotes Colorectal Carcinogenesis

Debao Fang, Hao Hu, Kailiang Zhao, Aman Xu, Changjun Yu, Yong Zhu, Ning Yu, Bo Yao, Suyun Tang, Xianning Wu, Yide Mei

Adv Sci (Weinh) 2023 Sep; 10(26): 2303336. Published online 2023 Jul 12. doi: 10.1002/advs.202303336

PMCID:: PMC10502657

Abstract Article PDF–3.4M

Select item 1048053519.

Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex

Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté

J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123

PMCID:: PMC10480535

Abstract Article PDF–2.4M

Select item 1046961220.

High-sensitivity profiling of SARS-CoV-2 noncoding region–host protein interactome reveals the potential regulatory role of negative-sense viral RNA

Liuyiqi Jiang, Mu Xiao, Qing-Qing Liao, Luqian Zheng, Chunyan Li, Yuemei Liu, Bing Yang, Aiming Ren, Chao Jiang, Xin-Hua Feng

mSystems. 2023 Jul-Aug; 8(4): e00135-23. Published online 2023 Jun 14. doi: 10.1128/msystems.00135-23

PMCID:: PMC10469612

Abstract Article PDF–4.0M

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