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Items: 1 to 20 of 112

1.
K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors
Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer
Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740
PMCID:
PMC11109483
AbstractArticlePDF–2.9M
2.
CDC6 may serve as an indicator of lung adenocarcinoma prognosis and progression based on TCGA and GEO data mining and experimental analyses
Hao Lou, Zelai Wu, Guangyou Wei
Oncol Rep. 2024 Feb; 51(2): 35. Published online 2024 Jan 3. doi: 10.3892/or.2024.8694
PMCID:
PMC10807357
AbstractArticlePDF–14M
3.
Role of TOP2A and CDC6 in liver cancer
Wei Jia, Xiang Liu, Zhilei Zhang
Medicine (Baltimore) 2023 Oct 20; 102(42): e35604. Published online 2023 Oct 20. doi: 10.1097/MD.0000000000035604
PMCID:
PMC10589547
AbstractArticlePDF–3.8M
4.
The E3 Ubiquitin Ligase SCF Cyclin F Promotes Sequestosome-1/p62 Insolubility and Foci Formation and is Dysregulated in ALS and FTD Pathogenesis
Jennilee M. Davidson, Sharlynn S. L. Wu, Stephanie L. Rayner, Flora Cheng, Kimberley Duncan, Carlo Russo, Michelle Newbery, Kunjie Ding, Natalie M. Scherer, Rachelle Balez, Alberto García-Redondo, Alberto Rábano, Livia Rosa-Fernandes, Lezanne Ooi, Kelly L. Williams, Marco Morsch, Ian P. Blair, Antonio Di Ieva, Shu Yang, Roger S. Chung, Albert Lee
Mol Neurobiol. 2023; 60(9): 5034–5054. Published online 2023 May 27. doi: 10.1007/s12035-023-03355-2
PMCID:
PMC10415446
AbstractArticlePDF–4.2M
5.
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains
Julia Jülg, Dieter Edbauer, Christian Behrends
EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895
PMCID:
PMC10398660
AbstractArticlePDF–2.4M
6.
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain
Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke
Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188
PMCID:
PMC9881136
AbstractArticlePDF–4.4M
7.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
8.
The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis
Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi
Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y
PMCID:
PMC9343455
AbstractArticlePDF–3.7M
9.
CDC6 is a prognostic biomarker and correlated with immune infiltrates in glioma
Feng Wang, Fen Zhao, Li Zhang, Lai Xiong, Qing Mao, Yanhui Liu, Xiaoguang Qiu, Xiang Wang, Lin Shui, Xi Chen, Kexing Ren, Pixian Shui, Qiongwen Zhang, Yifei Deng, Weimin Li, Xiaoqi Xie, Dengbin Wu, Tao Li, Jinyi Lang, Lei Liu, Huaying Chen, Jianguo Xu, Sen Bai, Zhiping Li, Qiang Yue, Ni Chen, Bingwen Zhou, Cheng Yi, Yuquan Wei, Yuchuan Fu, Yong Luo, Qiheng Gou, Lunxu Liu, Yuanzhao Liu, Jingbo Kang, Junjie Wang, Dongcun Jing, Fuquan Zhang, Xiaoyan Yang, Xianfeng Li, Tao Jiang, Zongcun Zhang, Yizhi Zhou, Junlin Yi
Mol Cancer. 2022; 21: 153. Published online 2022 Jul 25. doi: 10.1186/s12943-022-01623-8
PMCID:
PMC9316328
AbstractArticlePDF–2.1M
10.
FOXM1 Promotes Malignant Proliferation of Esophageal Squamous Cell Carcinoma Through Transcriptional Activating CDC6
Xiongfeng Chen, Jingbo Chen, Xunbin Yu, Guishan Lin, Ting Chen
DNA Cell Biol. July 2022; 41(7): 671–682. Published online 2022 Jul 4. doi: 10.1089/dna.2022.0169
PMCID:
PMC9293688
AbstractArticlePDF–1.0M
11.
The N-terminal cysteine is a dual sensor of oxygen and oxidative stress
Ah Jung Heo, Su Bin Kim, Chang Hoon Ji, Dohyun Han, Su Jin Lee, Su Hyun Lee, Min Ju Lee, Ji Su Lee, Aaron Ciechanover, Bo Yeon Kim, Yong Tae Kwon
Proc Natl Acad Sci U S A. 2021 Dec 14; 118(50): e2107993118. Published online 2021 Dec 10. doi: 10.1073/pnas.2107993118
PMCID:
PMC8685671
AbstractArticlePDF–3.1M
12.
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation
Jordan M. Meyers, Muthukumar Ramanathan, Ronald L. Shanderson, Aimee Beck, Laura Donohue, Ian Ferguson, Margaret G. Guo, Deepti S. Rao, Weili Miao, David Reynolds, Xue Yang, Yang Zhao, Yen-Yu Yang, Catherine Blish, Yinsheng Wang, Paul A. Khavari
PLoS Pathog. 2021 Oct; 17(10): e1009412. Published online 2021 Oct 1. doi: 10.1371/journal.ppat.1009412
PMCID:
PMC8513853
AbstractArticlePDF–4.1M
13.
SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition
Jian Ma, Qing Shi, Gaofeng Cui, Haoyue Sheng, Maria Victoria Botuyan, Yingke Zhou, Yuqian Yan, Yundong He, Liguo Wang, Yuzhuo Wang, Georges Mer, Dingwei Ye, Chenji Wang, Haojie Huang
Nat Commun. 2021; 12: 5779. Published online 2021 Oct 1. doi: 10.1038/s41467-021-26049-6
PMCID:
PMC8486843
AbstractArticlePDF–4.1M
14.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
15.
Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome
Jérémy A. Ferreira Barbosa, Samantha Sparapani, Jonathan Boulais, Robert Lodge, Éric A. Cohen
J Virol. 2021 Aug; 95(15): e00971-20. Prepublished online 2021 May 19. Published online 2021 Jul 12. doi: 10.1128/JVI.00971-20
PMCID:
PMC8274603
AbstractArticlePDF–4.2M
16.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
17.
Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication
Manzar Hossain, Kuhulika Bhalla, Bruce Stillman
Mol Cell. Author manuscript; available in PMC 2022 May 6.
Published in final edited form as: Mol Cell. 2021 May 6; 81(9): 1951–1969.e6. Published online 2021 Mar 23. doi: 10.1016/j.molcel.2021.03.003
PMCID:
PMC8106667
AbstractArticlePDF–2.8M
18.
Interactome analysis of gene expression profiles identifies CDC6 as a potential therapeutic target modified by miR-215-5p in hepatocellular carcinoma
Hongfa Xu, Jianwen Huang, Shengni Hua, Linjun Liang, Xu He, Meixiao Zhan, Ligong Lu, Jing Chu
Int J Med Sci. 2020; 17(18): 2926–2940. Published online 2020 Oct 18. doi: 10.7150/ijms.51145
PMCID:
PMC7646103
AbstractArticlePDF–3.5M
19.
Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion
Hyeon Gyu Seo, Han Byeol Kim, Ji Young Yoon, Tae Hyun Kweon, Yun Soo Park, Jingu Kang, Jinwoo Jung, SeongJin Son, Eugene C. Yi, Tae Ho Lee, Won Ho Yang, Jin Won Cho
Cell Death Dis. 2020 Sep; 11(9): 815. Published online 2020 Sep 29. doi: 10.1038/s41419-020-02999-5
PMCID:
PMC7525441
AbstractArticlePDF–3.7M
20.
Cdc6 as a novel target in cancer: Oncogenic potential, senescence and subcellular localisation
Nicholas Lim, Paul A. Townsend
Int J Cancer. 2020 Sep 15; 147(6): 1528–1534. Published online 2020 Feb 17. doi: 10.1002/ijc.32900
PMCID:
PMC7496346
AbstractArticlePDF–516K

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