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Items: 1 to 20 of 28

1.
Modulation of Titin and Contraction-Regulating Proteins in a Rat Model of Heart Failure with Preserved Ejection Fraction: Limb vs. Diaphragmatic Muscle
Beatrice Vahle, Leonard Heilmann, Antje Schauer, Antje Augstein, Maria-Elisa Prieto Jarabo, Peggy Barthel, Norman Mangner, Siegfried Labeit, T. Scott Bowen, Axel Linke, Volker Adams
Int J Mol Sci. 2024 Jun; 25(12): 6618. Published online 2024 Jun 16. doi: 10.3390/ijms25126618
PMCID:
PMC11203682
AbstractArticlePDF–2.4M
2.
Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins
Eli J. Larson, Zachery R. Gregorich, Yanghai Zhang, Brad H. Li, Timothy J. Aballo, Jake A. Melby, Ying Ge, Wei Guo
Mol Omics. Author manuscript; available in PMC 2023 Aug 15.
Published in final edited form as: Mol Omics. 2022 Aug 15; 18(7): 627–634. Published online 2022 Aug 15. doi: 10.1039/d2mo00115b
PMCID:
PMC9776116
AbstractArticlePDF–1.3M
3.
Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete’s Heart
Dalma Kellermayer, Bálint Kiss, Hedvig Tordai, Attila Oláh, Henk L. Granzier, Béla Merkely, Miklós Kellermayer, Tamás Radovits
Int J Mol Sci. 2021 Oct; 22(20): 11110. Published online 2021 Oct 15. doi: 10.3390/ijms222011110
PMCID:
PMC8537917
AbstractArticlePDF–1.9M
4.
RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity and Differential Hormonal Responses between Muscles and in Muscle Cell Cultures
Rexiati Maimaiti, Chaoqun Zhu, Yanghai Zhang, Qiyue Ding, Wei Guo
Int J Mol Sci. 2021 Mar; 22(6): 2928. Published online 2021 Mar 13. doi: 10.3390/ijms22062928
PMCID:
PMC7999644
AbstractArticlePDF–2.2M
5.
Comprehensive Analysis of Titin Protein Isoform and Alternative Splicing in Normal and Mutant Rats
Shijun Li, Wei Guo, Benjamin M. Schmitt, Marion L. Greaser
J Cell Biochem. Author manuscript; available in PMC 2019 Aug 16.
Published in final edited form as: J Cell Biochem. 2012 Apr; 113(4): 1265–1273. doi: 10.1002/jcb.23459
PMCID:
PMC6696936
AbstractArticlePDF–966K
6.
Truncations of the titin Z-disc predispose to a heart failure with preserved ejection phenotype in the context of pressure overload
Lei Ye, Liping Su, Chenxu Wang, Szejie Loo, Guizhen Tee, Shihua Tan, Sandar Win Khin, Shijie Ko, Boyang Su, Stuart A. Cook
PLoS One. 2018; 13(7): e0201498. Published online 2018 Jul 31. doi: 10.1371/journal.pone.0201498
PMCID:
PMC6067738
AbstractArticlePDF–7.2M
7.
Insulin regulates titin pre-mRNA splicing through the PI3K-Akt-mTOR kinase axis in a RBM20-dependent manner
Chaoqun Zhu, Zhiyong Yin, Bihua Tan, Wei Guo
Biochim Biophys Acta. Author manuscript; available in PMC 2018 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Sep; 1863(9): 2363–2371. Published online 2017 Jul 1. doi: 10.1016/j.bbadis.2017.06.023
PMCID:
PMC5547897
AbstractArticlePDF–1.3M
8.
Titin truncating variants affect heart function in disease cohorts and the general population
Sebastian Schafer, Antonio de Marvao, Eleonora Adami, Lorna R Fiedler, Benjamin Ng, Ester Khin, Owen J L Rackham, Sebastiaan van Heesch, Chee J Pua, Miao Kui, Roddy Walsh, Upasana Tayal, Sanjay K Prasad, Timothy J W Dawes, Nicole S J Ko, David Sim, Laura L Chan, Calvin W L Chin, Francesco Mazzarotto, Paul J Barton, Franziska Kreuchwig, Dominique P V de Kleijn, Teresa Totman, Carlo Biffi, Nicole Tee, Daniel Rueckert, Valentin Schneider, Allison Faber, Vera Regitz-Zagrosek, Jonathan G Seidman, Christine E Seidman, Wolfgang A Linke, Jean-Paul Kovalik, Declan Patrick O’Regan, James S Ware, Norbert Hubner, Stuart A Cook
Nat Genet. Author manuscript; available in PMC 2017 May 21.
Published in final edited form as: Nat Genet. 2017 Jan; 49(1): 46–53. Published online 2016 Nov 21. doi: 10.1038/ng.3719
PMCID:
PMC5201198
AbstractArticlePDF–1.9M
9.
Titin strain contributes to the Frank–Starling law of the heart by structural rearrangements of both thin- and thick-filament proteins
Younss Ait-Mou, Karen Hsu, Gerrie P. Farman, Mohit Kumar, Marion L. Greaser, Thomas C. Irving, Pieter P. de Tombe
Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8): 2306–2311. Published online 2016 Feb 8. doi: 10.1073/pnas.1516732113
PMCID:
PMC4776536
AbstractArticlePDF–1.1M
10.
Upstream Open Reading Frame in 5′-Untranslated Region Reduces Titin mRNA Translational Efficiency
Adrian G. Cadar, Lin Zhong, Angel Lin, Mauricio Valenzuela, Chee C. Lim
Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Oct 10.
Published in final edited form as: Biochem Biophys Res Commun. 2014 Oct 10; 453(1): 185–191. Published online 2014 Sep 27. doi: 10.1016/j.bbrc.2014.09.085
PMCID:
PMC4250383
AbstractArticlePDF–1.0M
11.
Titin-mediated control of cardiac myofibrillar function
Laurin M. Hanft, Marion L. Greaser, Kerry S. McDonald
Arch Biochem Biophys. Author manuscript; available in PMC 2015 Jun 15.
Published in final edited form as: Arch Biochem Biophys. 2014 Jun 15; 0: 83–91. Published online 2013 Nov 20. doi: 10.1016/j.abb.2013.11.005
PMCID:
PMC4028433
AbstractArticlePDF–755K
12.
Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms
Giulia Mearini, Christina Gedicke, Saskia Schlossarek, Christian C. Witt, Elisabeth Krämer, Peirang Cao, Marcelo D. Gomes, Stewart H. Lecker, Siegfried Labeit, Monte S. Willis, Thomas Eschenhagen, Lucie Carrier
Cardiovasc Res. 2010 Jan 15; 85(2): 357–366. Published online 2009 Oct 22. doi: 10.1093/cvr/cvp348
PMCID:
PMC4023316
AbstractArticlePDF–522K
13.
A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
Gaëlle Blandin, Sylvie Marchand, Karine Charton, Nathalie Danièle, Evelyne Gicquel, Jean-Baptiste Boucheteil, Azéddine Bentaib, Laetitia Barrault, Daniel Stockholm, Marc Bartoli, Isabelle Richard
Skelet Muscle. 2013; 3: 3. Published online 2013 Feb 15. doi: 10.1186/2044-5040-3-3
PMCID:
PMC3610214
AbstractArticlePDF–1.7M
14.
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
Wei Guo, Sebastian Schafer, Marion L. Greaser, Michael H. Radke, Martin Liss, Thirupugal Govindarajan, Henrike Maatz, Herbert Schulz, Shijun Li, Amanda M. Parrish, Vita Dauksaite, Padmanabhan Vakeel, Sabine Klaassen, Brenda Gerull, Ludwig Thierfelder, Vera Regitz-Zagrosek, Timothy A. Hacker, Kurt W. Saupe, G. William Dec, Patrick T. Ellinor, Calum A. MacRae, Bastian Spallek, Robert Fischer, Andreas Perrot, Cemil Özcelik, Kathrin Saar, Norbert Hubner, Michael Gotthardt
Nat Med. Author manuscript; available in PMC 2013 Feb 12.
Published in final edited form as: Nat Med. 2012 May; 18(5): 766–773. doi: 10.1038/nm.2693
PMCID:
PMC3569865
AbstractArticlePDF–3.5M
15.
Magnitude of length-dependent changes in contractile properties varies with titin isoform in rat ventricles
Jitandrakumar R. Patel, Jonathan M. Pleitner, Richard L. Moss, Marion L. Greaser
Am J Physiol Heart Circ Physiol. 2012 Feb 1; 302(3): H697–H708. Published online 2011 Dec 2. doi: 10.1152/ajpheart.00800.2011
PMCID:
PMC3353780
AbstractArticle
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Titin is a Target of MMP-2: Implications in Myocardial Ischemia/Reperfusion Injury
Mohammad A.M. Ali, Woo Jung Cho, Bryan Hudson, Zamaneh Kassiri, Henk Granzier, Richard Schulz
Circulation. Author manuscript; available in PMC 2011 Nov 16.
Published in final edited form as: Circulation. 2010 Nov 16; 122(20): 2039–2047. Published online 2010 Nov 1. doi: 10.1161/CIRCULATIONAHA.109.930222
PMCID:
PMC3057897
AbstractArticlePDF–1.7M
18.
Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes
Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper
J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406
PMCID:
PMC2637050
AbstractArticle
19.
Mechanoenzymatics of titin kinase
Elias M. Puchner, Alexander Alexandrovich, Ay Lin Kho, Ulf Hensen, Lars V. Schäfer, Birgit Brandmeier, Frauke Gräter, Helmut Grubmüller, Hermann E. Gaub, Mathias Gautel
Proc Natl Acad Sci U S A. 2008 Sep 9; 105(36): 13385–13390. Published online 2008 Sep 2. doi: 10.1073/pnas.0805034105
Correction in:
Proc Natl Acad Sci U S A. 2008 Dec 30; 105(52): 21045.
PMCID:
PMC2527993
AbstractArticlePDF–1.5M
20.
Smooth Muscle Titin Zq Domain Interaction with the Smooth Muscle α-Actinin Central Rod
Richard J. Chi, Alanna R. Simon, Ewa A. Bienkiewicz, Augustine Felix, Thomas C. S. Keller, III
J Biol Chem. 2008 Jul 25; 283(30): 20959–20967. doi: 10.1074/jbc.M709621200
PMCID:
PMC2475687
AbstractArticlePDF–631K

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