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Items: 1 to 20 of 42

1.
Pan-Cancer Analysis of the TRP Family, Especially TRPV4 and TRPC4, and Its Expression Correlated with Prognosis, Tumor Microenvironment, and Treatment Sensitivity
Zhenghao Chen, Youquan Zhao, Ye Tian, Rui Cao, Donghao Shang
Biomolecules. 2023 Feb; 13(2): 282. Published online 2023 Feb 2. doi: 10.3390/biom13020282
PMCID:
PMC9953180
AbstractArticlePDF–6.4M
2.
Expression of pH-Sensitive TRPC4 in Common Skin Tumors
Bernadett Kurz, Hannah Philine Michael, Antonia Förch, Susanne Wallner, Florian Zeman, Sonja-Maria Decking, Ines Ugele, Constantin Hintschich, Frank Haubner, Tobias Ettl, Kathrin Renner, Christoph Brochhausen, Stephan Schreml
Int J Mol Sci. 2023 Jan; 24(2): 1037. Published online 2023 Jan 5. doi: 10.3390/ijms24021037
PMCID:
PMC9862651
AbstractArticlePDF–2.8M
3.
Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation
Wenjun Zeng, Yinan Ji, Haiping Zhang, Liusheng Chen, Li Du, Ruiwei Guo
Genet Res (Camb) 2021; 2021: 2949986. Published online 2021 Nov 27. doi: 10.1155/2021/2949986
PMCID:
PMC8643255
AbstractArticlePDF–1.1M
4.
Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma
Osama M. Elzamzamy, Brandon E. Johnson, Wei-Chih Chen, Gangqing Hu, Reinhold Penner, Lori A. Hazlehurst
Cells. 2021 Jun; 10(6): 1490. Published online 2021 Jun 13. doi: 10.3390/cells10061490
PMCID:
PMC8231892
AbstractArticlePDF–5.3M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation
Cristina Guardia-Laguarta, Yuhui Liu, Knut H. Lauritzen, Hediye Erdjument-Bromage, Brittany Martin, Theresa C. Swayne, Xuejun Jiang, Serge Przedborski
J Neurosci. 2019 Sep 4; 39(36): 7074–7085. doi: 10.1523/JNEUROSCI.1691-18.2019
PMCID:
PMC6733537
AbstractArticlePDF–3.0M
7.
Differential PI(4,5)P2 sensitivities of TRPC4, C5 homomeric and TRPC1/4, C1/5 heteromeric channels
Juyeon Ko, Jongyun Myeong, Young-Cheul Shin, Insuk So
Sci Rep. 2019; 9: 1849. Published online 2019 Feb 12. doi: 10.1038/s41598-018-38443-0
PMCID:
PMC6372716
AbstractArticlePDF–4.9M
8.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
9.
Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers
Jongyun Myeong, Juyeon Ko, Misun Kwak, Jinsung Kim, Joohan Woo, Kotdaji Ha, Chansik Hong, Dongki Yang, Hyun Jin Kim, Ju-Hong Jeon, Insuk So
Sci Rep. 2018; 8: 12117. Published online 2018 Aug 14. doi: 10.1038/s41598-018-30625-0
PMCID:
PMC6092394
AbstractArticlePDF–3.5M
10.
Gαi-mediated TRPC4 activation by polycystin-1 contributes to endothelial function via STAT1 activation
Misun Kwak, Chansik Hong, Jongyun Myeong, Eunice Yon June Park, Ju-Hong Jeon, Insuk So
Sci Rep. 2018; 8: 3480. Published online 2018 Feb 22. doi: 10.1038/s41598-018-21873-1
PMCID:
PMC5823873
AbstractArticlePDF–5.2M
11.
Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory
Jenny Bröker‐Lai, Astrid Kollewe, Barbara Schindeldecker, Jörg Pohle, Vivan Nguyen Chi, Ilka Mathar, Raul Guzman, Yvonne Schwarz, Alan Lai, Petra Weißgerber, Herbert Schwegler, Alexander Dietrich, Martin Both, Rolf Sprengel, Andreas Draguhn, Georg Köhr, Bernd Fakler, Veit Flockerzi, Dieter Bruns, Marc Freichel
EMBO J. 2017 Sep 15; 36(18): 2770–2789. Published online 2017 Aug 8. doi: 10.15252/embj.201696369
PMCID:
PMC5599800
AbstractArticlePDF–4.2M
12.
Functional expression of calcium‐permeable canonical transient receptor potential 4‐containing channels promotes migration of medulloblastoma cells
Wei‐Chun Wei, Wan‐Chen Huang, Yu‐Ping Lin, Esther B. E. Becker, Olaf Ansorge, Veit Flockerzi, Daniele Conti, Giovanna Cenacchi, Maike D. Glitsch
J Physiol. 2017 Aug 15; 595(16): 5525–5544. Published online 2017 Jul 20. doi: 10.1113/JP274659
PMCID:
PMC5556167
AbstractArticlePDF–896K
13.
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels
Hussein N. Rubaiy, Melanie J. Ludlow, Matthias Henrot, Hannah J. Gaunt, Katarina Miteva, Sin Ying Cheung, Yasuyuki Tanahashi, Nurasyikin Hamzah, Katie E. Musialowski, Nicola M. Blythe, Hollie L. Appleby, Marc A. Bailey, Lynn McKeown, Roger Taylor, Richard Foster, Herbert Waldmann, Peter Nussbaumer, Mathias Christmann, Robin S. Bon, Katsuhiko Muraki, David J. Beech
J Biol Chem. 2017 May 19; 292(20): 8158–8173. Published online 2017 Mar 21. doi: 10.1074/jbc.M116.773556
PMCID:
PMC5437225
AbstractArticlePDF–3.8M
14.
TRPC4α and TRPC4β Similarly Affect Neonatal Cardiomyocyte Survival during Chronic GPCR Stimulation
Nadine Kirschmer, Sandra Bandleon, Viktor von Ehrlich-Treuenstätt, Sonja Hartmann, Alice Schaaf, Anna-Karina Lamprecht, Erick Miranda-Laferte, Tanja Langsenlehner, Oliver Ritter, Petra Eder
PLoS One. 2016; 11(12): e0168446. Published online 2016 Dec 19. doi: 10.1371/journal.pone.0168446
PMCID:
PMC5167390
AbstractArticlePDF–2.0M
15.
Identification of TRPCs genetic variants that modify risk for lung cancer based on the pathway and two-stage study
Zili Zhang, Jian Wang, Jianxing He, Xiansheng Zeng, Xindong Chen, Mingmei Xiong, Qipeng Zhou, Meihua Guo, Defu Li, Wenju Lu
Meta Gene. 2016 Sep; 9: 191–196. Published online 2016 Jul 8. doi: 10.1016/j.mgene.2016.07.005
PMCID:
PMC5006132
AbstractArticlePDF–271K
16.
Silencing of Transient Receptor Potential Channel 4 Alleviates oxLDL-induced Angiogenesis in Human Coronary Artery Endothelial Cells by Inhibition of VEGF and NF-κB
Wen Qin, Wei Xie, Ning Xia, Qinglin He, Tianwei Sun
Med Sci Monit. 2016; 22: 930–936. Published online 2016 Mar 21. doi: 10.12659/MSM.897634
PMCID:
PMC4805139
AbstractArticlePDF–1.1M
17.
Critical roles of Gi/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels
Dhananjay P. Thakur, Jin-bin Tian, Jaepyo Jeon, Jian Xiong, Yu Huang, Veit Flockerzi, Michael X. Zhu
Proc Natl Acad Sci U S A. 2016 Jan 26; 113(4): 1092–1097. Published online 2016 Jan 11. doi: 10.1073/pnas.1522294113
PMCID:
PMC4743816
AbstractArticlePDF–1.3M
18.
The Roles of Rasd1 small G proteins and leptin in the activation of TRPC4 transient receptor potential channels
Jinhong Wie, Byung Joo Kim, Jongyun Myeong, Kotdaji Ha, Seung Joo Jeong, Dongki Yang, Euiyong Kim, Ju-Hong Jeon, Insuk So
Channels (Austin) 2015 Jul-Aug; 9(4): 186–195. Published online 2015 Jun 17. doi: 10.1080/19336950.2015.1058454
Correction in:
Channels (Austin). 2016 Jul-Aug; 10(4): 332.
PMCID:
PMC4594510
AbstractArticlePDF–820K
19.
TRUSS, TNF-R1, and TRPC Ion Channels Synergistically Reverse Endoplasmic Reticulum Ca2+ Storage Reduction in Response to m1 Muscarinic Acetylcholine Receptor Signaling
Kimberly E. Mace, Marc P. Lussier, Guylain Boulay, Jennifer L. Terry-Powers, Helen Parfrey, Anne-Laure Perraud, David W.H. Riches
J Cell Physiol. Author manuscript; available in PMC 2015 May 28.
Published in final edited form as: J Cell Physiol. 2010 Nov; 225(2): 444–453. doi: 10.1002/jcp.22221
PMCID:
PMC4447216
AbstractArticlePDF–3.3M
20.
Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette Syndrome and Obsessive-Compulsive Disorder
Dongmei Yu, Carol A. Mathews, Jeremiah M. Scharf, Benjamin M. Neale, Lea K. Davis, Eric R. Gamazon, Eske M. Derks, Patrick Evans, Christopher K. Edlund, Jacquelyn Crane, Jesen A. Fagerness, Lisa Osiecki, Patience Gallagher, Gloria Gerber, Stephen Haddad, Cornelia Illmann, Lauren M. McGrath, Catherine Mayerfeld, Sampath Arepalli, Cristina Barlassina, Cathy L. Barr, Laura Bellodi, Fortu Benarroch, Gabriel Bedoya Berrió, O. Joseph Bienvenu, Donald Black, Michael H. Bloch, Helena Brentani, Ruth D. Bruun, Cathy L. Budman, Beatriz Camarena, Desmond D. Campbell, Carolina Cappi, Julio C. Cardona Silgado, Maria C. Cavallini, Denise A. Chavira, Sylvain Chouinard, Edwin H. Cook, M. R. Cookson, Vladimir Coric, Bernadette Cullen, Daniele Cusi, Richard Delorme, Damiaan Denys, Yves Dion, Valsama Eapen, Karin Egberts, Peter Falkai, Thomas Fernandez, Eduardo Fournier, Helena Garrido, Daniel Geller, Donald Gilbert, Simon L. Girard, Hans J. Grabe, Marco A. Grados, Benjamin D. Greenberg, Varda Gross-Tsur, Edna Grünblatt, John Hardy, Gary A. Heiman, Sian M.J. Hemmings, Luis D. Herrera, Dianne M. Hezel, Pieter J. Hoekstra, Joseph Jankovic, James L. Kennedy, Robert A. King, Anuar I. Konkashbaev, Barbara Kremeyer, Roger Kurlan, Nuria Lanzagorta, Marion Leboyer, James F. Leckman, Leonhard Lennertz, Chunyu Liu, Christine Lochner, Thomas L. Lowe, Sara Lupoli, Fabio Macciardi, Wolfgang Maier, Paolo Manunta, Maurizio Marconi, James T. McCracken, Sandra C. Mesa Restrepo, Rainald Moessner, Priya Moorjani, Jubel Morgan, Heike Muller, Dennis L. Murphy, Allan L. Naarden, William Cornejo Ochoa, Roel A. Ophoff, Andrew J. Pakstis, Michele T. Pato, Carlos N. Pato, John Piacentini, Christopher Pittenger, Yehuda Pollak, Scott L. Rauch, Tobias Renner, Victor I. Reus, Margaret A. Richter, Mark A. Riddle, Mary M. Robertson, Roxana Romero, Maria C. Rosário, David Rosenberg, Stephan Ruhrmann, Chiara Sabatti, Erika Salvi, Aline S. Sampaio, Jack Samuels, Paul Sandor, Susan K. Service, Brooke Sheppard, Harvey S. Singer, Jan H. Smit, Dan J. Stein, Eric Strengman, Jay A. Tischfield, Maurizio Turiel, Ana V. Valencia Duarte, Homero Vallada, Jeremy Veenstra-VanderWeele, Prof. Susanne Walitza, John Walkup, Ying Wang, Mike Weale, Robert Weiss, Jens R. Wendland, Herman G.M. Westenberg, Yin Yao, Ana G. Hounie, Euripedes C. Miguel, Humberto Nicolini, Michael Wagner, Andres Ruiz-Linares, Danielle C. Cath, William McMahon, Danielle Posthuma, Ben A. Oostra, Gerald Nestadt, Guy A. Rouleau, Shaun Purcell, Michael A. Jenike, Peter Heutink, Gregory L. Hanna, David V. Conti, Paul D. Arnold, Nelson Freimer, S. Evelyn Stewart, James A. Knowles, Nancy J. Cox, David L. Pauls
Am J Psychiatry. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Am J Psychiatry. 2015 Jan 1; 172(1): 82–93. Published online 2014 Oct 31. doi: 10.1176/appi.ajp.2014.13101306
PMCID:
PMC4282594
AbstractArticlePDF–1005K

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