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Select item 94674161.

LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis

Sixuan Wang, Jun Duan, Jiangquan Liao, Yan Wang, Xiang Xiao, Lin Li, Yi Liu, Huan Gu, Peng Yang, Dongliang Fu, Jinhang Du, Xianlun Li, Mingjing Shao

Aging (Albany NY) 2022 Aug 31; 14(16): 6809–6828. Published online 2022 Aug 30. doi: 10.18632/aging.204256

PMCID:: PMC9467416

Abstract Article PDF–2.1M

Select item 67406722.

Insulin Receptor Substrate-2 Deficiency Impairs Brain Growth and Promotes Tau Phosphorylation

Markus Schubert, Derek P. Brazil, Deborah J. Burks, Jake A. Kushner, Jing Ye, Carrie L. Flint, Janet Farhang-Fallah, Pieter Dikkes, Xavier M. Warot, Carlos Rio, Gabriel Corfas, Morris F. White

J Neurosci. 2003 Aug 6; 23(18): 7084–7092. doi: 10.1523/JNEUROSCI.23-18-07084.2003

PMCID:: PMC6740672

Abstract Article PDF–461K

Select item 63900553.

Expression and significance of EBV, ARID1A and PIK3CA in gastric carcinoma

Huan Zhou, Shun Tan, Hong Li, Xiangtao Lin

Mol Med Rep. 2019 Mar; 19(3): 2125–2136. Published online 2019 Jan 22. doi: 10.3892/mmr.2019.9886

PMCID:: PMC6390055

Abstract Article PDF–2.3M

Select item 56179284.

MiR‐339 inhibits proliferation of pulmonary artery smooth muscle cell by targeting FGF signaling

Jidong Chen, Xiaolei Cui, Li Li, Junle Qu, J. Usha Raj, Deming Gou

Physiol Rep. 2017 Sep; 5(18): e13441. Published online 2017 Sep 26. doi: 10.14814/phy2.13441

PMCID:: PMC5617928

Abstract Article PDF–1.6M

Select item 55810195.

Analysis of ESR1 and PIK3CA mutations in plasma cell-free DNA from ER-positive breast cancer patients

Takashi Takeshita, Yutaka Yamamoto, Mutsuko Yamamoto-Ibusuki, Mai Tomiguchi, Aiko Sueta, Keiichi Murakami, Yoko Omoto, Hirotaka Iwase

Oncotarget. 2017 Aug 8; 8(32): 52142–52155. Published online 2017 Jun 14. doi: 10.18632/oncotarget.18479

PMCID:: PMC5581019

Abstract Article PDF–2.3M

Select item 47136626.

PIK3CA polymorphisms associated with susceptibility to hepatocellular carcinoma

Hong-Guang Li, Fang-Feng Liu, Hua-Qiang Zhu, Xu Zhou, Jun Lu, Hong Chang, Jin-Hua Hu

Int J Clin Exp Pathol. 2015; 8(11): 15255–15259. Published online 2015 Nov 1.

PMCID:: PMC4713662

Abstract Article PDF–210K

Select item 44402547.

Garlic Oil Suppressed Nitrosodiethylamine-Induced Hepatocarcinoma in Rats by Inhibiting PI3K-AKT-NF-κB Pathway

Cui-Li Zhang, Tao Zeng, Xiu-Lan Zhao, Ke-Qin Xie

Int J Biol Sci. 2015; 11(6): 643–651. Published online 2015 Apr 25. doi: 10.7150/ijbs.10785

PMCID:: PMC4440254

Abstract Article PDF–1.4M

Select item 43421178.

The Mutational Landscape of Prostate Cancer

Christopher E. Barbieri, Chris H. Bangma, Anders Bjartell, James W. Catto, Zoran Culig, Henrik Gronberg, Jun Luo, Tapio Visakorpi, Mark A. Rubin

Eur Urol. Author manuscript; available in PMC 2015 Feb 26.

Published in final edited form as: Eur Urol. 2013 Oct; 64(4): 567–576. Published online 2013 May 18. doi: 10.1016/j.eururo.2013.05.029

PMCID:: PMC4342117

Abstract Article PDF–269K

Select item 42705469.

PIK3CA and PIK3CB expression and relationship with multidrug resistance in colorectal carcinoma

Feifei Wen, Shuang He, Chenbo Sun, Tangyue Li, Shuhua Wu

Int J Clin Exp Pathol. 2014; 7(11): 8295–8303. Published online 2014 Oct 15.

PMCID:: PMC4270546

Abstract Article PDF–1.0M

Select item 402506410.

Adipose tissue insulin resistance due to loss of PI3K p110α leads to decreased energy expenditure and obesity

Victoria L. B. Nelson, Ya-Ping Jiang, Kathleen G. Dickman, Lisa M. Ballou, Richard Z. Lin

Am J Physiol Endocrinol Metab. 2014 May 15; 306(10): E1205–E1216. Published online 2014 Apr 8. doi: 10.1152/ajpendo.00625.2013

PMCID:: PMC4025064

Abstract Article

Select item 400288511.

Involvement of Tissue Plasminogen Activator in Onset and Effector Phases of Experimental Allergic Encephalomyelitis

Weiquan Lu, Madhuri Bhasin, Stella E. Tsirka

J Neurosci. 2002 Dec 15; 22(24): 10781–10789. doi: 10.1523/JNEUROSCI.22-24-10781.2002

PMCID:: PMC4002885

Abstract Article PDF–1.3M

Select item 397535012.

HBx Protein Promotes Oval Cell Proliferation by Up-Regulation of Cyclin D1 via Activation of the MEK/ERK and PI3K/Akt Pathways

Heng-Yi Wang, Sheng-Li Yang, Hui-Fang Liang, Chang-Hai Li

Int J Mol Sci. 2014 Mar; 15(3): 3507–3518. Published online 2014 Feb 26. doi: 10.3390/ijms15033507

PMCID:: PMC3975350

Abstract Article PDF–606K

Select item 390754013.

Activation of the PI3K/mTOR Pathway Is Involved in Cystic Proliferation of Cholangiocytes of the PCK Rat

Xiang Shan Ren, Yasunori Sato, Kenichi Harada, Motoko Sasaki, Shinichi Furubo, Jing Yu Song, Yasuni Nakanuma

PLoS One. 2014; 9(1): e87660. Published online 2014 Jan 30. doi: 10.1371/journal.pone.0087660

PMCID:: PMC3907540

Abstract Article PDF–17M

Select item 381413914.

Endosomal acidification by Na⁺/H⁺ exchanger NHE5 regulates TrkA cell-surface targeting and NGF-induced PI3K signaling

Graham H. Diering, Yuka Numata, Steven Fan, John Church, Masayuki Numata

Mol Biol Cell. 2013 Nov 1; 24(21): 3435–3448. doi: 10.1091/mbc.E12-06-0445

PMCID:: PMC3814139

Abstract Article PDF–3.4M

Select item 379073915.

Leucine and HMB Differentially Modulate Proteasome System in Skeletal Muscle under Different Sarcopenic Conditions

Igor L. Baptista, Willian J. Silva, Guilherme G. Artioli, Joao Paulo L. F. Guilherme, Marcelo L. Leal, Marcelo S. Aoki, Elen H. Miyabara, Anselmo S. Moriscot

PLoS One. 2013; 8(10): e76752. Published online 2013 Oct 4. doi: 10.1371/journal.pone.0076752

Correction in:: PLoS One. 2013; 8(10): 10.1371/annotation/9060434b-c1df-4d52-8cda-88b9fbfaea51.

PMCID:: PMC3790739

Abstract Article PDF–2.4M

Select item 346140816.

Mosaic Overgrowth with Fibroadipose Hyperplasia is Caused by Somatic Activating Mutations in PIK3CA

Marjorie J Lindhurst, Victoria ER Parker, Felicity Payne, Julie C Sapp, Simon Rudge, Julie Harris, Alison M Witkowski, Qifeng Zhang, Matthijs P Groeneveld, Carol E Scott, Allan Daly, Susan M Huson, Laura L Tosi, Michael L Cunningham, Thomas N Darling, Joseph Geer, Zoran Gucev, V. Reid Sutton, Christos Tziotzios, Adrian K Dixon, Timothy Helliwell, Stephen O’Rahilly, David B Savage, Michael JO Wakelam, Inês Barroso, Leslie G Biesecker, Robert K Semple

Nat Genet. Author manuscript; available in PMC 2013 Feb 1.

Published in final edited form as: Nat Genet. 2012 Jun 24; 44(8): 928–933. Published online 2012 Jun 24. doi: 10.1038/ng.2332

PMCID:: PMC3461408

Abstract Article PDF–1.2M

Select item 334518117.

Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes

Marco Beauséjour, Dominique Noël, Sonya Thibodeau, Véronique Bouchard, Charlène Harnois, Jean-François Beaulieu, Marie-Josée Demers, Pierre H. Vachon

Apoptosis. 2012; 17(6): 566–578. Published online 2012 Mar 9. doi: 10.1007/s10495-012-0713-6

PMCID:: PMC3345181

Abstract Article PDF–649K

Select item 326678918.

An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice

Kathryn M. Kinross, Karen G. Montgomery, Margarete Kleinschmidt, Paul Waring, Ivan Ivetac, Anjali Tikoo, Mirette Saad, Lauren Hare, Vincent Roh, Theo Mantamadiotis, Karen E. Sheppard, Georgina L. Ryland, Ian G. Campbell, Kylie L. Gorringe, James G. Christensen, Carleen Cullinane, Rodney J. Hicks, Richard B. Pearson, Ricky W. Johnstone, Grant A. McArthur, Wayne A. Phillips

J Clin Invest. 2012 Feb 1; 122(2): 553–557. Published online 2012 Jan 3. doi: 10.1172/JCI59309

PMCID:: PMC3266789

Abstract Article PDF–3.3M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 310079920.

CONDITIONAL β-CATENIN LOSS IN MICE PROMOTES CHEMICAL HEPATOCARCINOGENESIS: ROLE OF OXIDATIVE STRESS & PDGFRα/PIK3CA SIGNALING

Xu-Feng Zhang, Xinping Tan, Gang Zeng, Amalea Misse, Sucha Singh, Youngsoo Kim, James E. Klaunig, Satdarshan P. S. Monga

Hepatology. Author manuscript; available in PMC 2011 May 24.

Published in final edited form as: Hepatology. 2010 Sep; 52(3): 954–965. doi: 10.1002/hep.23747

PMCID:: PMC3100799

Abstract Article PDF–2.0M

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