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Select item 88421651.

CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system

Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar

Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629

PMCID:: PMC8842165

Abstract Article PDF–3.0M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81366653.

DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist

Michel Thépaut, Joanna Luczkowiak, Corinne Vivès, Nuria Labiod, Isabelle Bally, Fátima Lasala, Yasmina Grimoire, Daphna Fenel, Sara Sattin, Nicole Thielens, Guy Schoehn, Anna Bernardi, Rafael Delgado, Franck Fieschi

PLoS Pathog. 2021 May; 17(5): e1009576. Published online 2021 May 20. doi: 10.1371/journal.ppat.1009576

PMCID:: PMC8136665

Abstract Article PDF–2.9M

Select item 81068834.

SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2

Qiao Lu, Jia Liu, Shuai Zhao, Maria Florencia Gomez Castro, Maudry Laurent-Rolle, Jianbo Dong, Xiaojuan Ran, Payal Damani-Yokota, Hongzhen Tang, Triantafyllia Karakousi, Juhee Son, Maria E. Kaczmarek, Ze Zhang, Stephen T. Yeung, Broc T. McCune, Rita E. Chen, Fei Tang, Xianwen Ren, Xufeng Chen, Jack C.C. Hsu, Marianna Teplova, Betty Huang, Haijing Deng, Zhilin Long, Tenny Mudianto, Shumin Jin, Peng Lin, Jasper Du, Ruochen Zang, Tina Tianjiao Su, Alberto Herrera, Ming Zhou, Renhong Yan, Jia Cui, James Zhu, Qiang Zhou, Tao Wang, Jianzhu Ma, Sergei B. Koralov, Zemin Zhang, Iannis Aifantis, Leopoldo N. Segal, Michael S. Diamond, Kamal M. Khanna, Kenneth A. Stapleford, Peter Cresswell, Yue Liu, Siyuan Ding, Qi Xie, Jun Wang

Immunity. 2021 Jun 8; 54(6): 1304–1319.e9. Published online 2021 May 9. doi: 10.1016/j.immuni.2021.05.006

PMCID:: PMC8106883

Abstract Article PDF–5.6M

Select item 78943185.

Structural Characterization of N‐Linked Glycans in the Receptor Binding Domain of the SARS‐CoV‐2 Spike Protein and their Interactions with Human Lectins

Maria Pia Lenza, Iker Oyenarte, Dr. Tammo Diercks, Jon Imanol Quintana, Dr. Ana Gimeno, Dr. Helena Coelho, Ana Diniz, Dr. Francesca Peccati, Sandra Delgado, Alexandre Bosch, Dr. Mikel Valle, Dr. Oscar Millet, Prof. Dr. Nicola G. A. Abrescia, Dr. Asís Palazón, Dr. Filipa Marcelo, Dr. Gonzalo Jiménez‐Osés, Prof. Dr. Jesús Jiménez‐Barbero, Dr. Ana Ardá, Dr. June Ereño‐Orbea

Angew Chem Int Ed Engl. 2020 Dec 21; 59(52): 23763–23771. Published online 2020 Oct 22. doi: 10.1002/anie.202011015

PMCID:: PMC7894318

Abstract Article PDF–2.3M

Select item 74322256.

N-Glycoproteins Have a Major Role in MGL Binding to Colorectal Cancer Cell Lines: Associations with Overall Proteome Diversity

Martina Pirro, Yassene Mohammed, Sandra J. van Vliet, Yoann Rombouts, Agnese Sciacca, Arnoud H. de Ru, George M. C. Janssen, Rayman T. N. Tjokrodirijo, Manfred Wuhrer, Peter A. van Veelen, Paul J. Hensbergen

Int J Mol Sci. 2020 Aug; 21(15): 5522. Published online 2020 Aug 1. doi: 10.3390/ijms21155522

PMCID:: PMC7432225

Abstract Article PDF–1.4M

Select item 71699837.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 67719138.

The C‐type lectin receptor MGL senses N‐acetylgalactosamine on the unique Staphylococcus aureus ST395 wall teichoic acid

Malgorzata E. Mnich, Rob van Dalen, David Gerlach, Astrid Hendriks, Guoqing Xia, Andreas Peschel, Jos A.G. van Strijp, Nina M. van Sorge

Cell Microbiol. 2019 Oct; 21(10): e13072. Published online 2019 Jul 8. doi: 10.1111/cmi.13072

PMCID:: PMC6771913

Abstract Article PDF–1.0M

Select item 63996739.

Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells

Martina Pirro, Esmee Schoof, Sandra J. van Vliet, Yoann Rombouts, Alexandre Stella, Arnoud de Ru, Yassene Mohammed, Manfred Wuhrer, Peter A. van Veelen, Paul J. Hensbergen

J Proteome Res. 2019 Mar 1; 18(3): 1125–1132. Published online 2018 Dec 24. doi: 10.1021/acs.jproteome.8b00796

PMCID:: PMC6399673

Abstract Article PDF–2.8M

Select item 593449510.

CLEC10A Is a Specific Marker for Human CD1c⁺ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion

Lukas Heger, Silke Balk, Jennifer J. Lühr, Gordon F. Heidkamp, Christian H. K. Lehmann, Lukas Hatscher, Ariawan Purbojo, Arndt Hartmann, Fayna Garcia-Martin, Shin-Ichiro Nishimura, Robert Cesnjevar, Falk Nimmerjahn, Diana Dudziak

Front Immunol. 2018; 9: 744. Published online 2018 Apr 27. doi: 10.3389/fimmu.2018.00744

PMCID:: PMC5934495

Abstract Article PDF–4.9M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 521788712.

Intermediate monocytes are increased in enthesitis‐related arthritis, a category of juvenile idiopathic arthritis

P. Gaur, A. Myles, R. Misra, A. Aggarwal

Clin Exp Immunol. 2017 Feb; 187(2): 234–241. Published online 2016 Oct 28. doi: 10.1111/cei.12880

PMCID:: PMC5217887

Abstract Article PDF–229K

Select item 469490113.

MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients

Kristiaan Lenos, Jeroen A.C.M. Goos, Ilona M. Vuist, Sjoerd H. den Uil, Pien M. Delis-van Diemen, Eric J.Th. Belt, Hein B.A.C. Stockmann, Herman Bril, Meike de Wit, Beatriz Carvalho, Susan Giblett, Catrin A. Pritchard, Gerrit A. Meijer, Yvette van Kooyk, Remond J.A. Fijneman, Sandra J. van Vliet

Oncotarget. 2015 Sep 22; 6(28): 26278–26290. Published online 2015 Jul 2. doi: 10.18632/oncotarget.4495

PMCID:: PMC4694901

Abstract Article PDF–3.4M

Select item 461721114.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 449304315.

The Macrophage Galactose-Type C-Type Lectin (MGL) Modulates Regulatory T Cell Functions

Ilaria Grazia Zizzari, Paola Martufi, Federico Battisti, Hassan Rahimi, Salvatore Caponnetto, Filippo Bellati, Marianna Nuti, Aurelia Rughetti, Chiara Napoletano

PLoS One. 2015; 10(7): e0132617. Published online 2015 Jul 6. doi: 10.1371/journal.pone.0132617

PMCID:: PMC4493043

Abstract Article PDF–1.2M

Select item 377974716.

Human T Cell Activation Results in Extracellular Signal-regulated Kinase (ERK)-Calcineurin-dependent Exposure of Tn Antigen on the Cell Surface and Binding of the Macrophage Galactose-type Lectin (MGL)

Sandra J. van Vliet, Ilona M. Vuist, Kristiaan Lenos, Boris Tefsen, Hakan Kalay, Juan J. García-Vallejo, Yvette van Kooyk

J Biol Chem. 2013 Sep 20; 288(38): 27519–27532. Published online 2013 Aug 5. doi: 10.1074/jbc.M113.471045

PMCID:: PMC3779747

Abstract Article PDF–6.8M

Select item 363669917.

Protein Domain Histochemistry (PDH): Binding of the Carbohydrate Recognition Domain (CRD) of Recombinant Human Glycoreceptor CLEC10A (CD301) to Formalin-Fixed, Paraffin-Embedded Breast Cancer Tissues

Peter Nollau, Gerrit Wolters-Eisfeld, Naghmeh Mortezai, Anna-Katharina Kurze, Birgit Klampe, Annegret Debus, Maximilian Bockhorn, Axel Niendorf, Christoph Wagener

J Histochem Cytochem. 2013 Mar; 61(3): 199–205. doi: 10.1369/0022155412474823

PMCID:: PMC3636699

Abstract Article PDF–3.1M

Select item 355934718.

Modulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1

Joachim Denner, Magdalena Eschricht, Michael Lauck, Marwan Semaan, Philipp Schlaermann, Hyunmi Ryu, Levent Akyüz

PLoS One. 2013; 8(1): e55199. Published online 2013 Jan 30. doi: 10.1371/journal.pone.0055199

PMCID:: PMC3559347

Abstract Article PDF–1.0M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 275772520.

Variation of Neisseria gonorrhoeae Lipooligosaccharide Directs Dendritic Cell–Induced T Helper Responses

Sandra J. van Vliet, Liana Steeghs, Sven C. M. Bruijns, Medi M. Vaezirad, Christian Snijders Blok, Jésus A. Arenas Busto, Marcel Deken, Jos P. M. van Putten, Yvette van Kooyk

PLoS Pathog. 2009 Oct; 5(10): e1000625. Published online 2009 Oct 16. doi: 10.1371/journal.ppat.1000625

PMCID:: PMC2757725

Abstract Article PDF–669K

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