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Select item 112233431.

DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition

Zhanqin Zhang, Jianguo Hu

J Transl Med. 2024; 22: 617. Published online 2024 Jul 3. doi: 10.1186/s12967-024-05402-5

PMCID:: PMC11223343

Abstract Article PDF–6.4M

Select item 111863572.

Endothelial Dickkopf-1 Promotes Smooth Muscle Cell-derived Foam Cell Formation via USP53-mediated Deubiquitination of SR-A During Atherosclerosis

Xiaolin Liu, Tengfei Zheng, Yu Zhang, Yachao Zhao, Fengming Liu, Shen Dai, Meng Zhang, Wencheng Zhang, Cheng Zhang, Mei Zhang, Xiao Li

Int J Biol Sci. 2024; 20(8): 2943–2964. Published online 2024 May 19. doi: 10.7150/ijbs.91957

PMCID:: PMC11186357

Abstract Article PDF–15M

Select item 111069113.

Dickkopf-1 (DKK1) blockade mitigates osteogenesis imperfecta (OI) related bone disease

Jih-Yang Ko, Feng-Sheng Wang, Wei-Shiung Lian, Fu-Shine Yang, Jeng-Wei Chen, Po-Hua Huang, Chin-Yi Liao, Shu-Jui Kuo

Mol Med. 2024; 30: 66. Published online 2024 May 21. doi: 10.1186/s10020-024-00838-3

PMCID:: PMC11106911

Abstract Article PDF–2.9M

Select item 109053274.

Involvement of DKK1 secreted from adipose‐derived stem cells in alopecia areata

Nahyun Choi, Juyeong Hwang, Doo Yeong Kim, Jino Kim, Seung Yong Song, Jong‐Hyuk Sung

Cell Prolif. 2024 Mar; 57(3): e13562. Published online 2023 Nov 22. doi: 10.1111/cpr.13562

PMCID:: PMC10905327

Abstract Article PDF–4.2M

Select item 108093895.

Profiles of Wnt pathway gene expression during tooth morphogenesis

Resmi Raju, Jeremie Oliver Piña, Daniela M. Roth, Parna Chattaraj, Fahad K. Kidwai, Fabio R. Faucz, James Iben, Gus Fridell, Ryan K. Dale, Rena N. D’Souza

Front Physiol. 2023; 14: 1316635. Published online 2024 Jan 10. doi: 10.3389/fphys.2023.1316635

PMCID:: PMC10809389

Abstract Article PDF–5.3M

Select item 107993936.

Fibroblasts inhibit osteogenesis by regulating nuclear-cytoplasmic shuttling of YAP in mesenchymal stem cells and secreting DKK1

Fei Huang, Guozhen Wei, Hai Wang, Ying Zhang, Wenbin Lan, Yun Xie, Gui Wu

Biol Res. 2024; 57: 4. Published online 2024 Jan 20. doi: 10.1186/s40659-023-00481-y

PMCID:: PMC10799393

Abstract Article PDF–14M

Select item 107573347.

Thrombocyte-derived Dickkopf1 promotes macrophage polarization in the Bleomycin-induced lung injury model

Eun-Ah Sung, Min Hee Park, SuJeong Song, Hasan Alanya, Octavian Henegariu, Jinze Liu, E Zeynep Erson-Omay, Patricia J. Sime, Wook-Jin Chae

Front Immunol. 2023; 14: 1247330. Published online 2023 Dec 15. doi: 10.3389/fimmu.2023.1247330

PMCID:: PMC10757334

Abstract Article PDF–2.8M

Select item 106541018.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 103971939.

Dickkopf1 induces enteric neurogenesis and gliogenesis in vitro if apoptosis is evaded

Melanie Scharr, Simon Scherer, Bernhard Hirt, Peter H. Neckel

Commun Biol. 2023; 6: 808. Published online 2023 Aug 2. doi: 10.1038/s42003-023-05072-x

PMCID:: PMC10397193

Abstract Article PDF–8.8M

Select item 1011290710.

Successful therapeutic intervention in new mouse models of frizzled 2-associated congenital malformations

Ryan P. Liegel, Megan N. Michalski, Sanika Vaidya, Elizabeth Bittermann, Erin Finnerty, Chelsea A. Menke, Cassandra R. Diegel, Zhendong A. Zhong, Bart O. Williams, Rolf W. Stottmann

Development. 2023 Feb 1; 150(3): dev201038. Published online 2023 Feb 15. doi: 10.1242/dev.201038

PMCID:: PMC10112907

Abstract Article

Select item 1008703411.

DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti‐DKK1 therapeutic DKN‐01

Edward J. Jarman, Marta Horcas‐Lopez, Scott H. Waddell, Stephanie MacMaster, Konstantinos Gournopanos, Daniel Y. H. Soong, Kamila I. Musialik, Panagiota Tsokkou, Minn‐E Ng, William A. Cambridge, David H. Wilson, Michael H. Kagey, Walter Newman, Jeffrey W. Pollard, Luke Boulter

Liver Int. 2023 Jan; 43(1): 208–220. Published online 2022 Sep 15. doi: 10.1111/liv.15383

PMCID:: PMC10087034

Abstract Article PDF–13M

Select item 976538212.

Dickkopf1 fuels inflammatory cytokine responses

Nikolai P. Jaschke, Sophie Pählig, Anupam Sinha, Timon E. Adolph, Maria Ledesma Colunga, Maura Hofmann, Andrew Wang, Sylvia Thiele, Julian Schwärzler, Alexander Kleymann, Marc Gentzel, Herbert Tilg, Ben Wielockx, Lorenz C. Hofbauer, Martina Rauner, Andy Göbel, Tilman D. Rachner

Commun Biol. 2022; 5: 1391. Published online 2022 Dec 20. doi: 10.1038/s42003-022-04368-8

PMCID:: PMC9765382

Abstract Article PDF–2.2M

Select item 971088113.

GATA3 mediates nonclassical β-catenin signaling in skeletal cell fate determination and ectopic chondrogenesis

Takamitsu Maruyama, Daigaku Hasegawa, Tomas Valenta, Jody Haigh, Maxime Bouchard, Konrad Basler, Wei Hsu

Sci Adv. 2022 Dec; 8(48): eadd6172. Published online 2022 Nov 30. doi: 10.1126/sciadv.add6172

PMCID:: PMC9710881

Abstract Article PDF–2.2M

Select item 938211714.

A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation

Tingxu Chen, Heather Alcorn, Sujan Devbhandari, Dirk Remus, Elizabeth Lacy, Danwei Huangfu, Kathryn V. Anderson

Biol Open. 2022 Aug 15; 11(8): bio059307. Published online 2022 Aug 8. doi: 10.1242/bio.059307

PMCID:: PMC9382117

Abstract Article PDF–10M

Select item 932084515.

Suppression of Sost/Sclerostin and Dickkopf‐1 Augment Intervertebral Disc Structure in Mice

Tori Kroon, Neharika Bhadouria, Paul Niziolek, Daniel Edwards, III, Roy Choi, Erica L Clinkenbeard, Alexander Robling, Nilsson Holguin

J Bone Miner Res. 2022 Jun; 37(6): 1156–1169. Published online 2022 Apr 20. doi: 10.1002/jbmr.4546

PMCID:: PMC9320845

Abstract Article PDF–22M

Select item 905090916.

Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients

Rihao Qu, Khusali Gupta, Danni Dong, Yiqun Jiang, Boris Landa, Charles Saez, Gwendolyn Strickland, Pei-lun Weng, M. Mark Taketo, Yuval Kluger, Peggy Myung

Dev Cell. Author manuscript; available in PMC 2023 Apr 25.

Published in final edited form as: Dev Cell. 2022 Apr 25; 57(8): 1053–1067.e5. Published online 2022 Apr 13. doi: 10.1016/j.devcel.2022.03.011

PMCID:: PMC9050909

Abstract Article PDF–3.4M

Select item 817138117.

Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism

Nobuyuki Kawamura, Katsuyoshi Takaoka, Hiroshi Hamada, Anna-Katerina Hadjantonakis, Ge-Hong Sun-Wada, Yoh Wada

Cell Rep. Author manuscript; available in PMC 2021 Jun 2.

Published in final edited form as: Cell Rep. 2020 Jun 9; 31(10): 107733. doi: 10.1016/j.celrep.2020.107733

PMCID:: PMC8171381

Abstract Article PDF–1.3M

Select item 815891818.

Ventricular, atrial, and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak

Kenzo Ivanovitch, Pablo Soro-Barrio, Probir Chakravarty, Rebecca A. Jones, Donald M. Bell, S. Neda Mousavy Gharavy, Despina Stamataki, Julien Delile, James C. Smith, James Briscoe

PLoS Biol. 2021 May; 19(5): e3001200. Published online 2021 May 17. doi: 10.1371/journal.pbio.3001200

PMCID:: PMC8158918

Abstract Article PDF–7.1M

Select item 796110619.

Mice lacking DKK1 in T cells exhibit high bone mass and are protected from estrogen-deficiency-induced bone loss

Juliane Lehmann, Sylvia Thiele, Ulrike Baschant, Tilman D. Rachner, Christof Niehrs, Lorenz C. Hofbauer, Martina Rauner

iScience. 2021 Mar 19; 24(3): 102224. Published online 2021 Feb 23. doi: 10.1016/j.isci.2021.102224

PMCID:: PMC7961106

Abstract Article PDF–4.3M

Select item 793877020.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

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