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Items: 1 to 20 of 26

1.
Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease
Dominic W. Kolonay, Kristina M. Sattler, Corinne Strawser, Jill Rafael-Fortney, Maria M. Mihaylova, Katherine E. Miller, Christoph Lepper, Kedryn K. Baskin
Front Cell Dev Biol. 2024; 12: 1331563. Published online 2024 Apr 16. doi: 10.3389/fcell.2024.1331563
PMCID:
PMC11058648
AbstractArticlePDF–3.8M
2.
Protein Tyrosine Phosphatase 1B Regulates miR-208b-Argonaute 2 Association and Thyroid Hormone Responsiveness in Cardiac Hypertrophy
Gérald Coulis, Avinash D. Londhe, Sudheer R. Sagabala, Yanfen Shi, David P. Labbé, Alexandre Bergeron, Pramod Sahadevan, Sherin A. Nawaito, Fatiha Sahmi, Marie Josse, Valérie Vinette, Marie-Claude Guertin, Gérard Karsenty, Michel L. Tremblay, Jean-Claude Tardif, Bruce G. Allen, Benoit Boivin
Sci Signal. Author manuscript; available in PMC 2022 Oct 19.
Published in final edited form as: Sci Signal. 2022 Apr 19; 15(730): eabn6875. Published online 2022 Apr 19. doi: 10.1126/scisignal.abn6875
PMCID:
PMC9125740
AbstractArticlePDF–1.5M
3.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
4.
Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network
Changming Tan, Siting Zhu, Zee Chen, Canzhao Liu, Yang E. Li, Mason Zhu, Zhiyuan Zhang, Zhiwei Zhang, Lunfeng Zhang, Yusu Gu, Zhengyu Liang, Thomas G. Boyer, Kunfu Ouyang, Sylvia M. Evans, Xi Fang
PLoS Genet. 2021 Sep; 17(9): e1009785. Published online 2021 Sep 10. doi: 10.1371/journal.pgen.1009785
PMCID:
PMC8432849
AbstractArticlePDF–3.4M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
The Mediator complex kinase module is necessary for fructose regulation of liver glycogen levels through induction of glucose-6-phosphatase catalytic subunit (G6pc)
Dou Yeon Youn, Alus M. Xiaoli, Haihong Zong, Junichi Okada, Li Liu, Jacob Pessin, Jeffrey E. Pessin, Fajun Yang
Mol Metab. 2021 Jun; 48: 101227. Published online 2021 Mar 31. doi: 10.1016/j.molmet.2021.101227
PMCID:
PMC8099662
AbstractArticlePDF–3.6M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Regulation of cardiac transcription by thyroid hormone and Med13
Rachel A. Minerath, Colleen M. Dewey, Duane D. Hall, Chad E. Grueter
J Mol Cell Cardiol. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: J Mol Cell Cardiol. 2019 Apr; 129: 27–38. Published online 2019 Feb 12. doi: 10.1016/j.yjmcc.2019.01.007
PMCID:
PMC6510257
AbstractArticlePDF–1.8M
9.
Mediator complex component MED13 regulates zygotic genome activation and is required for postimplantation development in the mouse
Yi-Liang Miao, Andrés Gambini, Yingpei Zhang, Elizabeth Padilla-Banks, Wendy N Jefferson, Miranda L Bernhardt, Weichun Huang, Leping Li, Carmen J Williams
Biol Reprod. 2018 Apr; 98(4): 449–464. Published online 2018 Jan 9. doi: 10.1093/biolre/ioy004
PMCID:
PMC6279059
AbstractArticlePDF–5.4M
10.
FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment
Emilia Dimitrova, Takashi Kondo, Angelika Feldmann, Manabu Nakayama, Yoko Koseki, Rebecca Konietzny, Benedikt M Kessler, Haruhiko Koseki, Robert J Klose
eLife. 2018; 7: e37084. Published online 2018 May 29. doi: 10.7554/eLife.37084
PMCID:
PMC5997449
AbstractArticlePDF–3.6M
11.
MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis
Beatriz Aranda-Orgilles, Ricardo Saldaña-Meyer, Eric Wang, Eirini Trompouki, Anne Fassl, Stephanie Lau, Jasper Mullenders, Pedro P. Rocha, Ramya Raviram, María Guillamot, María Sánchez-Díaz, Kun Wang, Clarisse Kayembe, Nan Zhang, Leonela Amoasii, Avik Choudhuri, Jane A. Skok, Markus Schober, Danny Reinberg, Piotr Sicinski, Heinrich Schrewe, Aristotelis Tsirigos, Leonard I. Zon, Iannis Aifantis
Cell Stem Cell. Author manuscript; available in PMC 2017 Jan 26.
Published in final edited form as: Cell Stem Cell. 2016 Dec 1; 19(6): 784–799. Published online 2016 Aug 25. doi: 10.1016/j.stem.2016.08.004
PMCID:
PMC5268820
AbstractArticlePDF–1.7M
12.
A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism
Leonela Amoasii, William Holland, Efrain Sanchez-Ortiz, Kedryn K. Baskin, Mackenzie Pearson, Shawn C. Burgess, Benjamin R. Nelson, Rhonda Bassel-Duby, Eric N. Olson
Genes Dev. 2016 Feb 15; 30(4): 434–446. doi: 10.1101/gad.273128.115
PMCID:
PMC4762428
AbstractArticlePDF–1.2M
13.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
14.
A cardiac microRNA governs systemic energy homeostasis by regulation of MED13
Chad E. Grueter, Eva van Rooij, Brett A. Johnson, Susan M. DeLeon, Lillian B. Sutherland, Xiaoxia Qi, Laurent Gautron, Joel K. Elmquist, Rhonda Bassel-Duby, Eric N. Olson
Cell. Author manuscript; available in PMC 2013 Apr 27.
Published in final edited form as: Cell. 2012 Apr 27; 149(3): 671–683. doi: 10.1016/j.cell.2012.03.029
PMCID:
PMC3340581
AbstractArticlePDF–4.6M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
17.
ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes
Arnaud R Krebs, Jeroen Demmers, Krishanpal Karmodiya, Nan-Chi Chang, Alice Chien Chang, László Tora
EMBO Rep. 2010 Jul; 11(7): 541–547. Published online 2010 May 28. doi: 10.1038/embor.2010.75
PMCID:
PMC2897115
AbstractArticlePDF–433K
18.
An Oct4-Centered Protein Interaction Network in Embryonic Stem Cells
Debbie L.C. van den Berg, Tim Snoek, Nick P. Mullin, Adam Yates, Karel Bezstarosti, Jeroen Demmers, Ian Chambers, Raymond A. Poot
Cell Stem Cell. 2010 Apr 2; 6(4): 369–381. doi: 10.1016/j.stem.2010.02.014
PMCID:
PMC2860243
AbstractArticle
19.
Discovery of Candidate Disease Genes in ENU–Induced Mouse Mutants by Large-Scale Sequencing, Including a Splice-Site Mutation in Nucleoredoxin
Melissa K. Boles, Bonney M. Wilkinson, Laurens G. Wilming, Bin Liu, Frank J. Probst, Jennifer Harrow, Darren Grafham, Kathryn E. Hentges, Lanette P. Woodward, Andrea Maxwell, Karen Mitchell, Michael D. Risley, Randy Johnson, Karen Hirschi, James R. Lupski, Yosuke Funato, Hiroaki Miki, Pablo Marin-Garcia, Lucy Matthews, Alison J. Coffey, Anne Parker, Tim J. Hubbard, Jane Rogers, Allan Bradley, David J. Adams, Monica J. Justice
PLoS Genet. 2009 Dec; 5(12): e1000759. Published online 2009 Dec 11. doi: 10.1371/journal.pgen.1000759
PMCID:
PMC2782131
AbstractArticlePDF–1.1M
20.
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice
Thomas E. Callis, Kumar Pandya, Hee Young Seok, Ru-Hang Tang, Mariko Tatsuguchi, Zhan-Peng Huang, Jian-Fu Chen, Zhongliang Deng, Bronwyn Gunn, Janelle Shumate, Monte S. Willis, Craig H. Selzman, Da-Zhi Wang
J Clin Invest. 2009 Sep 1; 119(9): 2772–2786. Published online 2009 Aug 10. doi: 10.1172/JCI36154
PMCID:
PMC2735902
AbstractArticlePDF–4.6M

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