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Items: 1 to 20 of 96

1.
AIF translocation into nucleus caused by Aifm1 R450Q mutation: generation and characterization of a mouse model for AUNX1
Tao Shi, Ziyi Chen, Jin Li, Hongyang Wang, Qiuju Wang
Hum Mol Genet. 2024 May 15; 33(10): 905–918. Published online 2024 Mar 6. doi: 10.1093/hmg/ddae010
PMCID:
PMC11070138
AbstractArticlePDF–3.6M
2.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders
Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz
Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700
PMCID:
PMC10769350
AbstractArticlePDF–11M
3.
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis
Jianxin Mao, Di Wang, Dong Wang, Qi Wu, Qiliang Shang, Chu Gao, Huanbo Wang, Han Wang, Mu Du, Pandi Peng, Haoruo Jia, Xiaolong Xu, Jie Wang, Liu Yang, Zhuojing Luo
Exp Mol Med. 2023 Jan; 55(1): 253–268. Published online 2023 Jan 18. doi: 10.1038/s12276-023-00928-y
PMCID:
PMC9898264
AbstractArticlePDF–9.1M
4.
AIFM1, negatively regulated by miR-145-5p, aggravates hypoxia-induced cardiomyocyte injury
Wugang Zhou, Lv Ji, Xuqin Liu, Dan Tu, Ningning Shi, Wangmu Yangqu, Shi Chen, Pingjin Gao, Hong Zhu, Chengchao Ruan
Biomed J. 2022 Dec; 45(6): 870–882. Published online 2021 Dec 1. doi: 10.1016/j.bj.2021.11.012
PMCID:
PMC9795367
AbstractArticlePDF–3.0M
5.
AIF Overexpression Aggravates Oxidative Stress in Neonatal Male Mice After Hypoxia–Ischemia Injury
Tao Li, Yanyan Sun, Shan Zhang, Yiran Xu, Kenan Li, Cuicui Xie, Yong Wang, Yafeng Wang, Jing Cao, Xiaoyang Wang, Josef M. Penninger, Guido Kroemer, Klas Blomgren, Changlian Zhu
Mol Neurobiol. 2022; 59(11): 6613–6631. Published online 2022 Aug 17. doi: 10.1007/s12035-022-02987-0
PMCID:
PMC9525408
AbstractArticlePDF–19M
6.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
7.
Comparative analysis of CI- and CIV-containing respiratory supercomplexes at single-cell resolution
Fabio Bertan, Lena Wischhof, Enzo Scifo, Mihaela Guranda, Joshua Jackson, Anaïs Marsal-Cots, Antonia Piazzesi, Miriam Stork, Michael Peitz, Jochen Herbert Martin Prehn, Dan Ehninger, Pierluigi Nicotera, Daniele Bano
Cell Rep Methods. 2021 May 24; 1(1): 100002. Published online 2021 Apr 2. doi: 10.1016/j.crmeth.2021.100002
PMCID:
PMC9017192
AbstractArticlePDF–5.9M
8.
Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy
Stephen P. Chelko, Gizem Keceli, Andrea Carpi, Nunzianna Doti, Jacopo Agrimi, Angeliki Asimaki, Carlos Bueno Beti, Matthew Miyamoto, Nuria Amat-Codina, Djahida Bedja, An-Chi Wei, Brittney Murray, Crystal Tichnell, Chulan Kwon, Hugh Calkins, Cynthia A. James, Brian O’Rourke, Marc K. Halushka, Edon Melloni, Jeffrey E. Saffitz, Daniel P. Judge, Menotti Ruvo, Richard N. Kitsis, Peter Andersen, Fabio Di Lisa, Nazareno Paolocci
Sci Transl Med. Author manuscript; available in PMC 2022 Mar 21.
Published in final edited form as: Sci Transl Med. 2021 Feb 17; 13(581): eabf0891. doi: 10.1126/scitranslmed.abf0891
PMCID:
PMC8936193
AbstractArticlePDF–3.6M
9.
The mitochondrial protease LONP1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals
Xiaoqiang Sheng, Chuanming Liu, Guijun Yan, Guangyu Li, Jingyu Liu, Yanjun Yang, Shiyuan Li, Zhongxun Li, Jidong Zhou, Xin Zhen, Yang Zhang, Zhenyu Diao, Yali Hu, Chuanhai Fu, Bin Yao, Chaojun Li, Yu Cao, Bin Lu, Zhongzhou Yang, Yingying Qin, Haixiang Sun, Lijun Ding
EBioMedicine. 2022 Jan; 75: 103790. Published online 2021 Dec 30. doi: 10.1016/j.ebiom.2021.103790
PMCID:
PMC8733232
AbstractArticlePDF–4.2M
10.
Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice
Vlatka Paštar, Mirela Lozić, Nela Kelam, Natalija Filipović, Branka Bernard, Yu Katsuyama, Katarina Vukojević
Int J Mol Sci. 2021 Oct; 22(19): 10712. Published online 2021 Oct 2. doi: 10.3390/ijms221910712
PMCID:
PMC8509723
AbstractArticlePDF–7.5M
11.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
12.
AIF3 splicing switch triggers neurodegeneration
Shuiqiao Liu, Mi Zhou, Zhi Ruan, Yanan Wang, Calvin Chang, Masayuki Sasaki, Veena Rajaram, Andrew Lemoff, Kalyani Nambiar, Jennifer E. Wang, Kimmo J. Hatanpaa, Weibo Luo, Ted M. Dawson, Valina L. Dawson, Yingfei Wang
Mol Neurodegener. 2021; 16: 25. Published online 2021 Apr 14. doi: 10.1186/s13024-021-00442-7
PMCID:
PMC8048367
AbstractArticlePDF–15M
13.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
14.
Alopecia in Harlequin mutant mice is associated with reduced AIF protein levels and expression of retroviral elements
Maik Hintze, Sebastian Griesing, Marion Michels, Birgit Blanck, Lena Wischhof, Dieter Hartmann, Daniele Bano, Thomas Franz
Mamm Genome. 2021; 32(1): 12–29. Published online 2020 Dec 26. doi: 10.1007/s00335-020-09854-0
PMCID:
PMC7878237
AbstractArticlePDF–2.7M
15.
Exercise Training and Neurodegeneration in Mitochondrial Disorders: Insights From the Harlequin Mouse
Miguel Fernández-de la Torre, Carmen Fiuza-Luces, Pedro L. Valenzuela, Sara Laine-Menéndez, Joaquín Arenas, Miguel A. Martín, Doug M. Turnbull, Alejandro Lucia, María Morán
Front Physiol. 2020; 11: 594223. Published online 2020 Dec 8. doi: 10.3389/fphys.2020.594223
PMCID:
PMC7752860
AbstractArticlePDF–4.3M
16.
Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus
Laure Delavallée, Navrita Mathiah, Lauriane Cabon, Aurélien Mazeraud, Marie-Noelle Brunelle-Navas, Leticia K. Lerner, Mariana Tannoury, Alexandre Prola, Raquel Moreno-Loshuertos, Mathieu Baritaud, Laura Vela, Kevin Garbin, Delphine Garnier, Christophe Lemaire, Francina Langa-Vives, Martine Cohen-Salmon, Patricio Fernández-Silva, Fabrice Chrétien, Isabelle Migeotte, Santos A. Susin
Mol Metab. 2020 Oct; 40: 101027. Published online 2020 May 30. doi: 10.1016/j.molmet.2020.101027
PMCID:
PMC7334469
AbstractArticlePDF–3.5M
17.
Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts
Federica De Majo, Jana-Charlotte Hegenbarth, Frank Rühle, Christian Bär, Thomas Thum, Martine de Boer, Dirk J. Duncker, Blanche Schroen, Anne-Sophie Armand, Monika Stoll, Leon J. De Windt
Sci Rep. 2020; 10: 8136. Published online 2020 May 18. doi: 10.1038/s41598-020-65115-9
PMCID:
PMC7235007
AbstractArticlePDF–5.4M
18.
Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice
Tao Li, Kenan Li, Shan Zhang, Yafeng Wang, Yiran Xu, Shane J. F. Cronin, Yanyan Sun, Yaodong Zhang, Cuicui Xie, Juan Rodriguez, Kai Zhou, Henrik Hagberg, Carina Mallard, Xiaoyang Wang, Josef M. Penninger, Guido Kroemer, Klas Blomgren, Changlian Zhu
Cell Death Dis. 2020 Jan; 11(1): 77. Published online 2020 Jan 30. doi: 10.1038/s41419-020-2280-z
PMCID:
PMC6992638
AbstractArticlePDF–4.2M
19.
AIF-regulated oxidative phosphorylation supports lung cancer development
Shuan Rao, Laura Mondragón, Blanka Pranjic, Toshikatsu Hanada, Gautier Stoll, Thomas Köcher, Peng Zhang, Alexander Jais, Alexander Lercher, Andreas Bergthaler, Daniel Schramek, Katharina Haigh, Valentina Sica, Marion Leduc, Nazanine Modjtahedi, Tsung-Pin Pai, Masahiro Onji, Iris Uribesalgo, Reiko Hanada, Ivona Kozieradzki, Rubina Koglgruber, Shane J. Cronin, Zhigang She, Franz Quehenberger, Helmut Popper, Lukas Kenner, Jody J. Haigh, Oliver Kepp, Malgorzata Rak, Kaican Cai, Guido Kroemer, Josef M. Penninger
Cell Res. 2019 Jul; 29(7): 579–591. Published online 2019 May 27. doi: 10.1038/s41422-019-0181-4
PMCID:
PMC6796841
AbstractArticlePDF–4.7M
20.
Apoptosis-Inducing Factor Substitutes for Caspase Executioners in NMDA-Triggered Excitotoxic Neuronal Death
Hongmin Wang, Seong-Woon Yu, David W. Koh, Jasmine Lew, Carmen Coombs, William Bowers, Howard J. Federoff, Guy G. Poirier, Ted M. Dawson, Valina L. Dawson
J Neurosci. 2004 Dec 1; 24(48): 10963–10973. doi: 10.1523/JNEUROSCI.3461-04.2004
PMCID:
PMC6730219
AbstractArticlePDF–650K

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