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Select item 111137971.

Role of p75 neurotrophin receptor in stem cell biology: more than just a marker

Elisa Tomellini, Chann Lagadec, Renata Polakowska, Xuefen Le Bourhis

Cell Mol Life Sci. 2014 Jul; 71(13): 2467–2481. Published online 2014 Jan 31. doi: 10.1007/s00018-014-1564-9

PMCID:: PMC11113797

Abstract Article PDF–612K

Select item 108551322.

Joint CB1 and NGF Receptor Activation Suppresses TRPM8 Activation in Etoposide-Resistant Retinoblastoma Cells

Szymon Ludwiczak, Jacqueline Reinhard, Peter S. Reinach, Aruna Li, Jakub Oronowicz, Aisha Yousf, Vinodh Kakkassery, Stefan Mergler

Int J Mol Sci. 2024 Feb; 25(3): 1733. Published online 2024 Jan 31. doi: 10.3390/ijms25031733

PMCID:: PMC10855132

Abstract Article PDF–3.0M

Select item 99656283.

The Nerve Growth Factor Receptor (NGFR/p75^NTR): A Major Player in Alzheimer’s Disease

Francesco Bruno, Paolo Abondio, Alberto Montesanto, Donata Luiselli, Amalia C. Bruni, Raffaele Maletta

Int J Mol Sci. 2023 Feb; 24(4): 3200. Published online 2023 Feb 6. doi: 10.3390/ijms24043200

PMCID:: PMC9965628

Abstract Article PDF–897K

Select item 98067684.

Isolation of an “Early” Transit Amplifying Keratinocyte Population in Human Epidermis: A Role for the Low Affinity Neurotrophin Receptor CD271

Roberta Lotti, Elisabetta Palazzo, Marika Quadri, Marc Dumas, Sylvianne Schnebert, Diego Biondini, Maria Anastasia Bianchini, Carine Nizard, Carlo Pincelli, Alessandra Marconi

Stem Cells. 2022 Dec; 40(12): 1149–1161. Published online 2022 Aug 29. doi: 10.1093/stmcls/sxac060

PMCID:: PMC9806768

Abstract Article PDF–28M

Select item 96631655.

Human immunomodulatory ligand B7-1 mediates synaptic remodeling via the p75 neurotrophin receptor

Nicholas C. Morano, Roshelle S. Smith, Victor Danelon, Ryan Schreiner, Uttsav Patel, Natalia G. Herrera, Carla Smith, Steven M. Olson, Michelle K. Laerke, Alev Celikgil, Scott J. Garforth, Sarah C. Garrett-Thomson, Francis S. Lee, Barbara L. Hempstead, Steven C. Almo

J Clin Invest. 2022 Nov 15; 132(22): e157002. Published online 2022 Nov 15. doi: 10.1172/JCI157002

PMCID:: PMC9663165

Abstract Article PDF–11M

Select item 96273686.

Association of rs2072446 in the NGFR gene with the risk of Alzheimer's disease and amyloid‐β deposition in the brain

Chen‐Yang He, Zuo‐Teng Wang, Ying‐Ying Shen, An‐Yu Shi, Hui‐Yun Li, Dong‐Wan Chen, Gui‐Hua Zeng, Cheng‐Rong Tan, Jin‐Tai Yu, Fan Zeng, Yan‐Jiang Wang, Alzheimer's Disease Neuroimaging Initiative

CNS Neurosci Ther. 2022 Dec; 28(12): 2218–2229. Published online 2022 Sep 8. doi: 10.1111/cns.13965

PMCID:: PMC9627368

Abstract Article PDF–2.0M

Select item 95880527.

RELA is required for CD271 expression and stem-like characteristics in hypopharyngeal cancer

Akira Nakazato, Mai Mochizuki, Rie Shibuya-Takahashi, Haruna Fujimori, Keitaro Fujii, Satoshi Saijoh, Shinkichi Morita, Tomoko Yamazaki, Takayuki Imai, Ikuro Sato, Kennichi Satoh, Kazunori Yamaguchi, Kazuo Sugamura, Jun Yasuda, Kazuto Matsuura, Hideo Shojaku, Yukinori Asada, Keiichi Tamai

Sci Rep. 2022; 12: 17751. Published online 2022 Oct 22. doi: 10.1038/s41598-022-22736-6

PMCID:: PMC9588052

Abstract Article PDF–2.1M

Select item 95336668.

Neurotrophin Pathway Receptors NGFR and TrkA Control Perineural Invasion, Metastasis and Pain in Oral Cancer

Coleen Doan, Bradley E. Aouizerat, Yi Ye, Dongmin Dang, Kesava Asam, Aditi Bhattacharya, Timothy Howard, Yogin K. Patel, Dan T. Viet, Johnny D. Figueroa, Jiang F. Zhong, Carissa M. Thomas, Anthony B. Morlandt, Gary Yu, Nicholas F. Callahan, Clint T. Allen, Anupama Grandhi, Alan S. Herford, Paul C. Walker, Khanh Nguyen, Stephanie C. Kidd, Steve C. Lee, Jared C. Inman, Jason M. Slater, Chi T. Viet

Adv Biol (Weinh) Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Adv Biol (Weinh). 2022 Sep; 6(9): e2200190. Published online 2022 Aug 4. doi: 10.1002/adbi.202200190

PMCID:: PMC9533666

Abstract Article PDF–1.9M

Select item 89899929.

SorCS3 promotes the internalization of p75^NTR to inhibit GBM progression

Yanqiu Zhang, Yue Li, Yuhua Fan, Xiaoyuan Zhang, Zhihong Tang, Jing Qi, Baoshan Zhao, Fuyuan Li, Xiaofeng Chen, Huan Liang, Haiyan Xu, Dongliang Li

Cell Death Dis. 2022 Apr; 13(4): 313. Published online 2022 Apr 7. doi: 10.1038/s41419-022-04753-5

PMCID:: PMC8989992

Abstract Article PDF–8.5M

Select item 893165910.

Pro Nerve Growth Factor and Its Receptor p75NTR Activate Inflammatory Responses in Synovial Fibroblasts: A Novel Targetable Mechanism in Arthritis

Luciapia Farina, Gaetana Minnone, Stefano Alivernini, Ivan Caiello, Lucy MacDonald, Marzia Soligo, Luigi Manni, Barbara Tolusso, Simona Coppola, Erika Zara, Libenzio Adrian Conti, Angela Aquilani, Silvia Magni-Manzoni, Mariola Kurowska-Stolarska, Elisa Gremese, Fabrizio De Benedetti, Luisa Bracci-Laudiero

Front Immunol. 2022; 13: 818630. Published online 2022 Mar 4. doi: 10.3389/fimmu.2022.818630

PMCID:: PMC8931659

Abstract Article PDF–6.3M

Select item 870887911.

Live-Cell Imaging of Single Neurotrophin Receptor Molecules on Human Neurons in Alzheimer’s Disease

Klaudia Barabás, Julianna Kobolák, Soma Godó, Tamás Kovács, Dávid Ernszt, Miklós Kecskés, Csaba Varga, Tibor Z. Jánosi, Takahiro Fujiwara, Akihiro Kusumi, Annamária Téglási, András Dinnyés, István M. Ábrahám

Int J Mol Sci. 2021 Dec; 22(24): 13260. Published online 2021 Dec 9. doi: 10.3390/ijms222413260

PMCID:: PMC8708879

Abstract Article PDF–2.5M

Select item 847408012.

Evolution of Delayed Resistance to Immunotherapy in a Melanoma Responder

David Liu, Jia-Ren Lin, Emily J Robitschek, Gyulnara G Kasumova, Alex Heyde, Alvin Shi, Adam Kraya, Gao Zhang, Tabea Moll, Dennie T Frederick, Yu-An Chen, Shu Wang, Denis Schapiro, Li-Lun Ho, Kevin Bi, Avinash Sahu, Shaolin Mei, Benchun Miao, Tatyana Sharova, Christopher Alvarez-Breckenridge, Jackson H Stocking, Tommy Kim, Riley Fadden, Donald Lawrence, Mai P Hoang, Daniel P Cahill, Mohsen Malehmir, Martin A Nowak, Priscilla K Brastianos, Christine G Lian, Eytan Ruppin, Benjamin Izar, Meenhard Herlyn, Eliezer M Van Allen, Katherine Nathanson, Keith T Flaherty, Ryan J Sullivan, Manolis Kellis, Peter K Sorger, Genevieve M Boland

Nat Med. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Nat Med. 2021 Jun; 27(6): 985–992. Published online 2021 May 3. doi: 10.1038/s41591-021-01331-8

PMCID:: PMC8474080

Article PDF–4.3M

Select item 831891713.

Structural basis of NF-κB signaling by the p75 neurotrophin receptor interaction with adaptor protein TRADD through their respective death domains

Ning Zhang, Lilian Kisiswa, Ajeena Ramanujan, Zhen Li, Eunice Weiling Sim, Xianbin Tian, Wensu Yuan, Carlos F. Ibáñez, Zhi Lin

J Biol Chem. 2021 Aug; 297(2): 100916. Published online 2021 Jun 25. doi: 10.1016/j.jbc.2021.100916

Correction in:: J Biol Chem. 2022 Nov; 298(11): 102583.

PMCID:: PMC8318917

Abstract Article PDF–3.9M

Select item 794896114.

Proteomic identification and validation of novel interactions of the putative tumor suppressor PRELP with membrane proteins including IGFI-R and p75NTR

Hirofumi Kosuge, Makoto Nakakido, Satoru Nagatoishi, Tetsuya Fukuda, Yasuhiko Bando, Shin-ichi Ohnuma, Kouhei Tsumoto

J Biol Chem. 2021 Jan-Jun; 296: 100278. Published online 2021 Jan 9. doi: 10.1016/j.jbc.2021.100278

PMCID:: PMC7948961

Abstract Article PDF–1.3M

Select item 790509115.

Tissue-Specificity of Antibodies Raised Against TrkB and p75^NTR Receptors; Implications for Platelets as Models of Neurodegenerative Diseases

Samuel Fleury, Imane Boukhatem, Jessica Le Blanc, Mélanie Welman, Marie Lordkipanidzé

Front Immunol. 2021; 12: 606861. Published online 2021 Feb 11. doi: 10.3389/fimmu.2021.606861

PMCID:: PMC7905091

Abstract Article PDF–2.4M

Select item 787030016.

p75NTR/proBDNF Modulates Basal Cell Carcinoma (BCC) Immune Microenvironment via Necroptosis Signaling Pathway

Qingli Lu, Yuanyuan Qu, Yuan Ding, Xiaojing Kang

J Immunol Res. 2021; 2021: 6652846. Published online 2021 Feb 1. doi: 10.1155/2021/6652846

PMCID:: PMC7870300

Abstract Article PDF–1.9M

Select item 778010717.

The p75^NTR and its carboxyl‐terminal fragment exert opposing effects on melanoma cell proliferation and apoptosis via modulation of the NF‐κB pathway

Maojiao Zhong, Yingying Wang, Farrukh Nisar Muhammad, Jing Gao, Chunxiang Bian

FEBS Open Bio. 2021 Jan; 11(1): 226–236. Published online 2020 Dec 16. doi: 10.1002/2211-5463.13047

PMCID:: PMC7780107

Abstract Article PDF–2.9M

Select item 774974018.

Inhibition of tumor suppressor p73 by nerve growth factor receptor via chaperone-mediated autophagy

Daniel Nguyen, Kun Yang, Lucia Chiao, Yun Deng, Xiang Zhou, Zhen Zhang, Shelya X Zeng, Hua Lu

J Mol Cell Biol. 2020 Sep; 12(9): 700–712. Published online 2020 Apr 13. doi: 10.1093/jmcb/mjaa017

PMCID:: PMC7749740

Abstract Article PDF–1.6M

Select item 752736719.

Valproic acid upregulates the expression of the p75NTR/sortilin receptor complex to induce neuronal apoptosis

Simona Dedoni, Luisa Marras, Maria C. Olianas, Angela Ingianni, Pierluigi Onali

Apoptosis. 2020; 25(9): 697–714. Published online 2020 Jul 25. doi: 10.1007/s10495-020-01626-0

PMCID:: PMC7527367

Abstract Article PDF–8.4M

Select item 748637920.

A comprehensive p75 neurotrophin receptor gene network and pathway analyses identifying new target genes

Antti Sajanti, Seán B. Lyne, Romuald Girard, Janek Frantzén, Tomi Rantamäki, Iiro Heino, Ying Cao, Cassiano Diniz, Juzoh Umemori, Yan Li, Riikka Takala, Jussi P. Posti, Susanna Roine, Fredrika Koskimäki, Melissa Rahi, Jaakko Rinne, Eero Castrén, Janne Koskimäki

Sci Rep. 2020; 10: 14984. Published online 2020 Sep 11. doi: 10.1038/s41598-020-72061-z

PMCID:: PMC7486379

Abstract Article PDF–21M

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