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Select item 109750271.

miRNA‑21 promotes the progression of acute liver failure via the KLF6/autophagy/IL‑23 signaling pathway

Suxia Bao, Weiyang Zheng, Rong Yan, Jie Xu

Mol Med Rep. 2024 May; 29(5): 80. Published online 2024 Mar 19. doi: 10.3892/mmr.2024.13205

PMCID:: PMC10975027

Abstract Article PDF–5.8M

Select item 109014632.

A genome-wide genetic screen uncovers determinants of human pigmentation

Vivek K. Bajpai, Tomek Swigut, Jaaved Mohammed, Sahin Naqvi, Martin Arreola, Josh Tycko, Tayne C. Kim, Jonathan K. Pritchard, Michael C. Bassik, Joanna Wysocka

Science. Author manuscript; available in PMC 2024 Feb 28.

Published in final edited form as: Science. 2023 Aug 11; 381(6658): eade6289. Published online 2023 Aug 11. doi: 10.1126/science.ade6289

PMCID:: PMC10901463

Abstract Article PDF–1.9M

Select item 108420263.

Essential role of Mg²⁺ in mouse preimplantation embryo development revealed by TRPM7 chanzyme-deficient gametes

Neha Gupta, Cristina Soriano-Úbeda, Paula Stein, Virginia Savy, Brian N. Papas, Goli Ardestani, Ingrid Carvacho, Dominique Alfandari, Carmen J. Williams, Rafael A. Fissore

Cell Rep. Author manuscript; available in PMC 2024 Feb 5.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113232. Published online 2023 Oct 11. doi: 10.1016/j.celrep.2023.113232

PMCID:: PMC10842026

Abstract Article PDF–3.0M

Select item 106511224.

Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development

Justin Malin, Gustavo Ulises Martinez-Ruiz, Yongge Zhao, Susannah C. Shissler, Jennifer E. Cowan, Yi Ding, Abigail Morales-Sanchez, Masaki Ishikawa, Marieke Lavaert, Arundhoti Das, Donna Butcher, Andrew C. Warner, Melissa Kallarakal, Jingqiu Chen, Noemi Kedei, Michael Kelly, Lauren R. Brinster, David Allman, Avinash Bhandoola

Sci Adv. 2023 Nov 17; 9(46): eadg8126. Published online 2023 Nov 15. doi: 10.1126/sciadv.adg8126

PMCID:: PMC10651122

Abstract Article PDF–1.6M

Select item 103138965.

KLF6 alleviates hepatic ischemia-reperfusion injury by inhibiting autophagy

Jiye Li, Dongsheng Yu, Chenhui He, Qiwen Yu, Zhongkun Huo, Yi Zhang, Shuijun Zhang

Cell Death Dis. 2023 Jul; 14(7): 393. Published online 2023 Jul 1. doi: 10.1038/s41419-023-05872-3

PMCID:: PMC10313896

Abstract Article PDF–8.8M

Select item 89401776.

Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity

Catarina Catela, Yihan Chen, Yifei Weng, Kailong Wen, Paschalis Kratsios

eLife. 2022; 11: e70766. Published online 2022 Mar 22. doi: 10.7554/eLife.70766

PMCID:: PMC8940177

Abstract Article PDF–6.0M

Select item 86484637.

Identification of KLF6/PSGs and NPY-Related USF2/CEACAM Transcriptional Regulatory Networks via Spinal Cord Bulk and Single-Cell RNA-Seq Analysis

Xinbing Liu, Wei Gao, Wei Liu

Dis Markers. 2021; 2021: 2826609. Published online 2021 Nov 29. doi: 10.1155/2021/2826609

PMCID:: PMC8648463

Abstract Article PDF–5.6M

Select item 85208148.

Long noncoding RNA ZBED3‐AS1 restrains breast cancer progression by targeting the microRNA‐513a‐5p/KLF6 axis

Aiqin Fu, Ze Yu, Enning Zhang, Jijie Song

Thorac Cancer. 2021 Oct; 12(20): 2719–2731. Published online 2021 Aug 24. doi: 10.1111/1759-7714.14111

PMCID:: PMC8520814

Abstract Article PDF–9.1M

Select item 82018529.

Krüppel-like factor 6–mediated loss of BCAA catabolism contributes to kidney injury in mice and humans

Sian E. Piret, Yiqing Guo, Ahmed A. Attallah, Sylvia J. Horne, Amy Zollman, Daniel Owusu, Justina Henein, Viktoriya S. Sidorenko, Monica P. Revelo, Takashi Hato, Avi Ma’ayan, John Cijiang He, Sandeep K. Mallipattu

Proc Natl Acad Sci U S A. 2021 Jun 8; 118(23): e2024414118. Published online 2021 May 31. doi: 10.1073/pnas.2024414118

PMCID:: PMC8201852

Abstract Article PDF–3.1M

Select item 794876210.

Cell autonomous angiotensin II signaling controls the pleiotropic functions of oncogenic K-Ras

Daniela Volonte, Morgan Sedorovitz, Victoria E. Cespedes, Maria L. Beecher, Ferruccio Galbiati

J Biol Chem. 2021 Jan-Jun; 296: 100242. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015188

PMCID:: PMC7948762

Abstract Article PDF–5.7M

Select item 777403911.

Kruppel‐like factor 6 promotes macrophage inflammatory and hypoxia response

Gun‐Dong Kim, Hang Pong Ng, E. Ricky Chan, Ganapati H. Mahabeleshwar

FASEB J. 2020 Feb; 34(2): 3209–3223. Published online 2020 Jan 6. doi: 10.1096/fj.201902221R

PMCID:: PMC7774039

Abstract Article PDF–2.0M

Select item 709381212.

Klf6 protects β-cells against insulin resistance-induced dedifferentiation

Christopher Dumayne, David Tarussio, Ana Rodriguez Sanchez-Archidona, Alexandre Picard, Davide Basco, Xavier Pascal Berney, Mark Ibberson, Bernard Thorens

Mol Metab. 2020 May; 35: 100958. Published online 2020 Feb 6. doi: 10.1016/j.molmet.2020.02.001

PMCID:: PMC7093812

Abstract Article PDF–2.7M

Select item 704475413.

CBX4 transcriptionally suppresses KLF6 via interaction with HDAC1 to exert oncogenic activities in clear cell renal cell carcinoma

Nan Jiang, Gang Niu, Ying-Hua Pan, Wenwei Pan, Mei-Fang Zhang, Chris Zhiyi Zhang, Huimin Shen

EBioMedicine. 2020 Mar; 53: 102692. Published online 2020 Feb 26. doi: 10.1016/j.ebiom.2020.102692

PMCID:: PMC7044754

Abstract Article PDF–4.5M

Select item 676664514.

Kruppel-like factor 6 and miR-223 signaling axis regulates macrophage-mediated inflammation

Gun-Dong Kim, Hang Pong Ng, Nibedita Patel, Ganapati H. Mahabeleshwar

FASEB J. 2019 Oct; 33(10): 10902–10915. Published online 2019 Jun 29. doi: 10.1096/fj.201900867RR

PMCID:: PMC6766645

Abstract Article

Select item 663328715.

Serum Response Factor Is Required for Cortical Axon Growth But Is Dispensable for Neurogenesis and Neocortical Lamination

Paul P. Y. Lu, Narendrakumar Ramanan

J Neurosci. 2011 Nov 16; 31(46): 16651–16664. doi: 10.1523/JNEUROSCI.3015-11.2011

PMCID:: PMC6633287

Abstract Article PDF–7.8M

Select item 655639716.

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST

Yoko Nakano, Susan Wiechert, Botond Bánfi

Cell Rep. Author manuscript; available in PMC 2019 Jun 9.

Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 860–871.e8. doi: 10.1016/j.celrep.2019.03.072

PMCID:: PMC6556397

Abstract Article PDF–2.3M

Select item 651731717.

Sox2 Acts in Thalamic Neurons to Control the Development of Retina-Thalamus-Cortex Connectivity

Sara Mercurio, Linda Serra, Alessia Motta, Lorenzo Gesuita, Luisa Sanchez-Arrones, Francesca Inverardi, Benedetta Foglio, Cristiana Barone, Polynikis Kaimakis, Ben Martynoga, Sergio Ottolenghi, Michèle Studer, Francois Guillemot, Carolina Frassoni, Paola Bovolenta, Silvia K. Nicolis

iScience. 2019 May 31; 15: 257–273. Published online 2019 Apr 26. doi: 10.1016/j.isci.2019.04.030

PMCID:: PMC6517317

Abstract Article PDF–17M

Select item 639844718.

Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes

Toru Suzuki, Chisato Kikuguchi, Saori Nishijima, Takeshi Nagashima, Akinori Takahashi, Mariko Okada, Tadashi Yamamoto

Development. 2019 Feb 15; 146(4): dev168146. Published online 2019 Feb 15. doi: 10.1242/dev.168146

PMCID:: PMC6398447

Abstract Article

Select item 638138819.

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System

Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund

Gastroenterology. 2018 Feb; 154(3): 624–636. doi: 10.1053/j.gastro.2017.10.005

PMCID:: PMC6381388

Abstract Article

Select item 619834220.

Podocyte-Specific Loss of Krüppel-Like Factor 6 Increases Mitochondrial Injury in Diabetic Kidney Disease

Sylvia J. Horne, Jessica M. Vasquez, Yiqing Guo, Victoria Ly, Sian E. Piret, Alexandra R. Leonardo, Jason Ling, Monica P. Revelo, Daniel Bogenhagen, Vincent W. Yang, John C. He, Sandeep K. Mallipattu

Diabetes. 2018 Nov; 67(11): 2420–2433. Published online 2018 Aug 16. doi: 10.2337/db17-0958