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Items: 1 to 20 of 31

1.
HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
Joan Sala-Gaston, Leonardo Pedrazza, Juanma Ramirez, Arturo Martinez-Martinez, Lettie E. Rawlins, Emma L. Baple, Andrew H. Crosby, Ugo Mayor, Francesc Ventura, Jose Luis Rosa
Cell Mol Life Sci. 2022; 79(11): 548. Published online 2022 Oct 14. doi: 10.1007/s00018-022-04586-7
PMCID:
PMC9568463
AbstractArticlePDF–7.5M
2.
Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter
Dolores Piniella, Elena Martínez-Blanco, David Bartolomé-Martín, Ana B. Sanz-Martos, Francisco Zafra
Cell Mol Life Sci. 2021 Dec; 78(23): 7733–7756. Published online 2021 Oct 28. doi: 10.1007/s00018-021-03998-1
PMCID:
PMC8629785
AbstractArticlePDF–10M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
5.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
6.
Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J
Steven Timmermans, Claude Libert
JCI Insight. 2018 Jul 12; 3(13): e121758. Published online 2018 Jul 12. doi: 10.1172/jci.insight.121758
PMCID:
PMC6124530
AbstractArticlePDF–358K
7.
RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain
Pamela Valnegri, Ju Huang, Tomoko Yamada, Yue Yang, Luis A. Mejia, Ha Y. Cho, Anna Oldenborg, Azad Bonni
Nat Commun. 2017; 8: 1271. Published online 2017 Nov 2. doi: 10.1038/s41467-017-01333-6
PMCID:
PMC5668370
AbstractArticlePDF–2.2M
8.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
9.
The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination
Monica Cubillos-Rojas, Taiane Schneider, Ouadah Hadjebi, Leonardo Pedrazza, Jarbas Rodrigues de Oliveira, Francina Langa, Jean-Louis Guénet, Joan Duran, Josep Maria de Anta, Soledad Alcántara, Rocio Ruiz, Eva María Pérez-Villegas, Francisco J. Aguilar, Ángel M. Carrión, Jose Angel Armengol, Emma Baple, Andrew H. Crosby, Ramon Bartrons, Francesc Ventura, Jose Luis Rosa
Oncotarget. 2016 Aug 30; 7(35): 56083–56106. Published online 2016 Aug 12. doi: 10.18632/oncotarget.11270
PMCID:
PMC5302898
AbstractArticlePDF–15M
10.
Novel gene function revealed by mouse mutagenesis screens for models of age-related disease
Paul K. Potter, Michael R. Bowl, Prashanthini Jeyarajan, Laura Wisby, Andrew Blease, Michelle E. Goldsworthy, Michelle M. Simon, Simon Greenaway, Vincent Michel, Alun Barnard, Carlos Aguilar, Thomas Agnew, Gareth Banks, Andrew Blake, Lauren Chessum, Joanne Dorning, Sara Falcone, Laurence Goosey, Shelley Harris, Andy Haynes, Ines Heise, Rosie Hillier, Tertius Hough, Angela Hoslin, Marie Hutchison, Ruairidh King, Saumya Kumar, Heena V. Lad, Gemma Law, Robert E. MacLaren, Susan Morse, Thomas Nicol, Andrew Parker, Karen Pickford, Siddharth Sethi, Becky Starbuck, Femke Stelma, Michael Cheeseman, Sally H. Cross, Russell G. Foster, Ian J. Jackson, Stuart N. Peirson, Rajesh V. Thakker, Tonia Vincent, Cheryl Scudamore, Sara Wells, Aziz El-Amraoui, Christine Petit, Abraham Acevedo-Arozena, Patrick M. Nolan, Roger Cox, Anne-Marie Mallon, Steve D. M. Brown
Nat Commun. 2016; 7: 12444. Published online 2016 Aug 18. doi: 10.1038/ncomms12444
PMCID:
PMC4992138
AbstractArticlePDF–2.2M
11.
The Parkinson’s Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway
Yuzuru Imai, Yoshito Kobayashi, Tsuyoshi Inoshita, Hongrui Meng, Taku Arano, Kengo Uemura, Takeshi Asano, Kenji Yoshimi, Chang-Liang Zhang, Gen Matsumoto, Toshiyuki Ohtsuka, Ryoichiro Kageyama, Hiroshi Kiyonari, Go Shioi, Nobuyuki Nukina, Nobutaka Hattori, Ryosuke Takahashi
PLoS Genet. 2015 Sep; 11(9): e1005503. Published online 2015 Sep 10. doi: 10.1371/journal.pgen.1005503
PMCID:
PMC4565672
AbstractArticlePDF–11M
12.
Degradation of the Deubiquitinating Enzyme USP33 Is Mediated by p97 and the Ubiquitin Ligase HERC2
Nickie C. Chan, Willem den Besten, Michael J. Sweredoski, Sonja Hess, Raymond J. Deshaies, David C. Chan
J Biol Chem. 2014 Jul 11; 289(28): 19789–19798. Published online 2014 May 22. doi: 10.1074/jbc.M114.569392
PMCID:
PMC4094088
AbstractArticlePDF–1.5M
13.
The Central Role of EED in the Orchestration of Polycomb Group Complexes
Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan
Nat Commun. Author manuscript; available in PMC 2014 Jul 24.
Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127
PMCID:
PMC4073494
AbstractArticlePDF–2.1M
14.
The E3 Ubiquitin Protein Ligase HERC2 Modulates the Activity of Tumor Protein p53 by Regulating Its Oligomerization
Monica Cubillos-Rojas, Fabiola Amair-Pinedo, Roser Peiró-Jordán, Ramon Bartrons, Francesc Ventura, Jose Luis Rosa
J Biol Chem. 2014 May 23; 289(21): 14782–14795. Published online 2014 Apr 9. doi: 10.1074/jbc.M113.527978
PMCID:
PMC4031533
AbstractArticlePDF–3.6M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Physical and Functional Interaction of the HECT Ubiquitin-protein Ligases E6AP and HERC2
Simone Kühnle, Ulrike Kogel, Sandra Glockzin, Andreas Marquardt, Aaron Ciechanover, Konstantin Matentzoglu, Martin Scheffner
J Biol Chem. 2011 Jun 3; 286(22): 19410–19416. Published online 2011 Apr 14. doi: 10.1074/jbc.M110.205211
PMCID:
PMC3103319
AbstractArticlePDF–1.9M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
19.
Effects on Sperm Morphology by Alleles at the Pink-Eyed Dilution Locus in Mice
H. Glenn Wolfe, Robert P. Erickson, Linda C. Schmidt
Genetics. 1977 Feb; 85(2): 303–308. doi: 10.1093/genetics/85.2.303
PMCID:
PMC1213633
SummaryPDF–340K
20.
Molecular Analysis of 36 Mutations at the Mouse Pink-Eyed Dilution (P) Locus
D. K. Johnson, L. J. Stubbs, C. T. Culiat, C. S. Montgomery, L. B. Russell, E. M. Rinchik
Genetics. 1995 Dec; 141(4): 1563–1571. doi: 10.1093/genetics/141.4.1563
PMCID:
PMC1206887
SummaryPDF–894K

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