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Select item 107535871.

Loss of NR5A1 in mouse Sertoli cells after sex determination changes cellular identity and induces cell death by anoikis

Sirine Souali-Crespo, Diana Condrea, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Erwan Grandgirard, Violaine Alunni, Marie Cerciat, Matthieu Jung, Chloé Mayere, Serge Nef, Manuel Mark, Frédéric Chalmel, Norbert B. Ghyselinck

Development. 2023 Dec 15; 150(24): dev201710. Published online 2023 Dec 11. doi: 10.1242/dev.201710

PMCID:: PMC10753587

Abstract Article

Select item 105455402.

Unique functional responses differentially map onto genetic subtypes of dopamine neurons

Maite Azcorra, Zachary Gaertner, Connor Davidson, Qianzi He, Hailey Kim, Shivathmihai Nagappan, Cooper K. Hayes, Charu Ramakrishnan, Lief Fenno, Yoon Seok Kim, Karl Deisseroth, Richard Longnecker, Rajeshwar Awatramani, Daniel A. Dombeck

Nat Neurosci. 2023; 26(10): 1762–1774. Published online 2023 Aug 3. doi: 10.1038/s41593-023-01401-9

PMCID:: PMC10545540

Abstract Article PDF–31M

Select item 104824293.

Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation

Wilma Tixi, Maricela Maldonado, Ya-Ting Chang, Amy Chiu, Wilson Yeung, Nazia Parveen, Michael S Nelson, Ryan Hart, Shihao Wang, Wu Jih Hsu, Patrick Fueger, Janel L Kopp, Mark O Huising, Sangeeta Dhawan, Hung Ping Shih

eLife. 2023; 12: e90006. Published online 2023 Aug 23. doi: 10.7554/eLife.90006

PMCID:: PMC10482429

Abstract Article PDF–26M

Select item 102360014.

Stem cell decoupling underlies impaired lymphoid development during aging

Geunhyo Jang, Stephania Contreras Castillo, Eduardo Esteva, Samik Upadhaya, Jue Feng, Nicholas M. Adams, Elodie Richard, Rajeshwar Awatramani, Catherine M. Sawai, Boris Reizis

Proc Natl Acad Sci U S A. 2023 May 30; 120(22): e2302019120. Published online 2023 May 22. doi: 10.1073/pnas.2302019120

PMCID:: PMC10236001

Abstract Article PDF–3.9M

Select item 98628085.

Neuronal Dot1l Activity Acts as a Mitochondrial Gene-Repressor Associated with Human Brain Aging via H3K79 Hypermethylation

Hendrikus J. Van Heesbeen, Lars Von Oerthel, Paul M. De Vries, Cindy M. R. J. Wagemans, Marten P. Smidt

Int J Mol Sci. 2023 Jan; 24(2): 1387. Published online 2023 Jan 10. doi: 10.3390/ijms24021387

PMCID:: PMC9862808

Abstract Article PDF–6.0M

Select item 96038606.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 91862957.

ALDH1A1 overexpression in melanoma cells promotes tumor angiogenesis by activating the IL-8/Notch signaling cascade

Valerio Ciccone, Erika Terzuoli, Emma Ristori, Arianna Filippelli, Marina Ziche, Lucia Morbidelli, Sandra Donnini

Int J Mol Med. 2022 Jul; 50(1): 99. Published online 2022 Jun 2. doi: 10.3892/ijmm.2022.5155

PMCID:: PMC9186295

Abstract Article PDF–6.1M

Select item 90979748.

Inhibitory co-transmission from midbrain dopamine neurons relies on presynaptic GABA uptake

Riccardo Melani, Nicolas X. Tritsch

Cell Rep. Author manuscript; available in PMC 2022 May 12.

Published in final edited form as: Cell Rep. 2022 Apr 19; 39(3): 110716. doi: 10.1016/j.celrep.2022.110716

PMCID:: PMC9097974

Abstract Article PDF–2.0M

Select item 90974499.

Global Deletion of ALDH1A1 and ALDH1A2 Genes Does Not Affect Viability but Blocks Spermatogenesis

Traci Topping, Michael D. Griswold

Front Endocrinol (Lausanne) 2022; 13: 871225. Published online 2022 Apr 28. doi: 10.3389/fendo.2022.871225

PMCID:: PMC9097449

Abstract Article PDF–1.0M

Select item 901811910.

Regulation of Prefrontal Patterning and Connectivity by Retinoic Acid

Mikihito Shibata, Kartik Pattabiraman, Belen Lorente-Galdos, David Andrijevic, Suel-Kee Kim, Navjot Kaur, Sydney K. Muchnik, Xiaojun Xing, Gabriel Santpere, Andre M. M. Sousa, Nenad Sestan

Nature. Author manuscript; available in PMC 2022 Apr 19.

Published in final edited form as: Nature. 2021 Oct; 598(7881): 483–488. Published online 2021 Oct 1. doi: 10.1038/s41586-021-03953-x

PMCID:: PMC9018119

Abstract Article PDF–12M

Select item 894017611.

Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration

Ryoji Amamoto, Grace K Wallick, Constance L Cepko

eLife. 2022; 11: e76389. Published online 2022 Mar 22. doi: 10.7554/eLife.76389

PMCID:: PMC8940176

Abstract Article PDF–3.4M

Select item 865804012.

Nkx2.9 Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate

Willemieke M. Kouwenhoven, Lars von Oerthel, Maria Gruppilo, Jianmin Tian, Cindy M. R. J. Wagemans, Imke G. J. Houwers, Joseph Locker, Simone Mesman, Marten P. Smidt

Int J Mol Sci. 2021 Dec; 22(23): 12663. Published online 2021 Nov 23. doi: 10.3390/ijms222312663

PMCID:: PMC8658040

Abstract Article PDF–7.2M

Select item 860775313.

Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins

Milagros Pereira Luppi, Maite Azcorra, Giuliana Caronia-Brown, Jean-Francois Poulin, Zachary Gaertner, Serafin Gatica, Oscar Andrés Moreno-Ramos, Navid Nouri, Marilyn Dubois, Yongchao C. Ma, Charu Ramakrishnan, Lief Fenno, Yoon Seok Kim, Karl Deisseroth, Francesca Cicchetti, Daniel A. Dombeck, Rajeshwar Awatramani

Cell Rep. Author manuscript; available in PMC 2021 Nov 22.

Published in final edited form as: Cell Rep. 2021 Nov 9; 37(6): 109975. doi: 10.1016/j.celrep.2021.109975

PMCID:: PMC8607753

Abstract Article PDF–3.5M

Select item 854930514.

Synaptic dysfunction of Aldh1a1 neurons in the ventral tegmental area causes impulsive behaviors

Xinyan Li, Wenting Chen, Xian Huang, Wei Jing, Tongmei Zhang, Quntao Yu, Hongyan Yu, Hao Li, Qing Tian, Yumei Ding, Youming Lu

Mol Neurodegener. 2021; 16: 73. Published online 2021 Oct 26. doi: 10.1186/s13024-021-00494-9

Correction in:: Mol Neurodegener. 2023; 18: 33.

PMCID:: PMC8549305

Abstract Article PDF–17M

Select item 853051215.

Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction

Fabio Da Silva, Fariba Jian Motamedi, Lahiru Chamara Weerasinghe Arachchige, Amelie Tison, Stephen T Bradford, Jonathan Lefebvre, Pascal Dolle, Norbert B Ghyselinck, Kay D Wagner, Andreas Schedl

eLife. 2021; 10: e68280. Published online 2021 Oct 8. doi: 10.7554/eLife.68280

PMCID:: PMC8530512

Abstract Article PDF–21M

Select item 818971916.

Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris

Brent A Wilkerson, Heather L Zebroski, Connor R Finkbeiner, Alex D Chitsazan, Kylie E Beach, Nilasha Sen, Renee C Zhang, Olivia Bermingham-McDonogh

eLife. 2021; 10: e60108. Published online 2021 May 18. doi: 10.7554/eLife.60108

PMCID:: PMC8189719

Abstract Article PDF–15M

Select item 810615817.

Fli1 deficiency suppresses RALDH1 activity of dermal dendritic cells and related induction of regulatory T cells: a possible role in scleroderma

Shunsuke Miura, Yusuke Watanabe, Ryosuke Saigusa, Takashi Yamashita, Kouki Nakamura, Megumi Hirabayashi, Takuya Miyagawa, Ayumi Yoshizaki, Maria Trojanowska, Shinichi Sato, Yoshihide Asano

Arthritis Res Ther. 2021; 23: 137. Published online 2021 May 8. doi: 10.1186/s13075-021-02520-z

PMCID:: PMC8106158

Abstract Article PDF–1.1M

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 770785119.

Local retinoic acid signaling directs emergence of the extraocular muscle functional unit

Glenda Evangelina Comai, Markéta Tesařová, Valérie Dupé, Muriel Rhinn, Pedro Vallecillo-García, Fabio da Silva, Betty Feret, Katherine Exelby, Pascal Dollé, Leif Carlsson, Brian Pryce, François Spitz, Sigmar Stricker, Tomáš Zikmund, Jozef Kaiser, James Briscoe, Andreas Schedl, Norbert B. Ghyselinck, Ronen Schweitzer, Shahragim Tajbakhsh

PLoS Biol. 2020 Nov; 18(11): e3000902. Published online 2020 Nov 17. doi: 10.1371/journal.pbio.3000902

PMCID:: PMC7707851

Abstract Article PDF–5.0M

Select item 764932420.

Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling

Parivash Nouri, Sebastian Götz, Benedict Rauser, Martin Irmler, Changgeng Peng, Dietrich Trümbach, Christian Kempny, Carina G. Lechermeier, Agnes Bryniok, Andrea Dlugos, Ellen Euchner, Johannes Beckers, Claude Brodski, Claudia Klümper, Wolfgang Wurst, Nilima Prakash

Front Cell Dev Biol. 2020; 8: 587778. Published online 2020 Oct 26. doi: 10.3389/fcell.2020.587778

PMCID:: PMC7649324

Abstract Article PDF–13M

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