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Select item 100790181.

Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN

Wei-Lun Hsu, Yun-Li Ma, Yan-Chu Chen, Yen-Chen Liu, Kuang-Min Cheng, Eminy H. Y. Lee

PLoS One. 2023; 18(4): e0283908. Published online 2023 Apr 6. doi: 10.1371/journal.pone.0283908

PMCID:: PMC10079018

Abstract Article PDF–2.5M

Select item 83132392.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 74159913.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 69137804.

Ndfip Proteins Target Robo Receptors for Degradation and Allow Commissural Axons to Cross the Midline in the Developing Spinal Cord

Madhavi Gorla, Celine Santiago, Karina Chaudhari, Awo Akosua Kesewa Layman, Paula M. Oliver, Greg J. Bashaw

Cell Rep. Author manuscript; available in PMC 2019 Dec 16.

Published in final edited form as: Cell Rep. 2019 Mar 19; 26(12): 3298–3312.e4. doi: 10.1016/j.celrep.2019.02.080

PMCID:: PMC6913780

Abstract Article PDF–2.9M

Select item 66739575.

Nedd4-WW Domain-Binding Protein 5 (Ndfip1) Is Associated with Neuronal Survival after Acute Cortical Brain Injury

Qian Sang, Mary H. Kim, Sharad Kumar, Nicole Bye, Maria C. Morganti-Kossman, Jenny Gunnersen, Stephanie Fuller, Jason Howitt, Lavinia Hyde, Tim Beissbarth, Hamish S. Scott, John Silke, Seong-Seng Tan

J Neurosci. 2006 Jul 5; 26(27): 7234–7244. doi: 10.1523/JNEUROSCI.1398-06.2006

PMCID:: PMC6673957

Abstract Article PDF–1.1M

Select item 61129806.

The Ubiquitin Ligase Adaptor NDFIP1 Selectively Enforces a CD8⁺ T Cell Tolerance Checkpoint to High-Dose Antigen

Mayura V. Wagle, Julia M. Marchingo, Jason Howitt, Seong-Seng Tan, Christopher C. Goodnow, Ian A. Parish

Cell Rep. Author manuscript; available in PMC 2018 Aug 28.

Published in final edited form as: Cell Rep. 2018 Jul 17; 24(3): 577–584. doi: 10.1016/j.celrep.2018.06.060

PMCID:: PMC6112980

Abstract Article PDF–833K

Select item 56069297.

NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation

Christiane Trimpert, Daniel Wesche, Theun de Groot, Martha M. Pimentel Rodriguez, Victoria Wong, Dennis T. M. van den Berg, Lydie Cheval, Carolina A. Ariza, Alain Doucet, Igor Stagljar, Peter M. T. Deen

PLoS One. 2017; 12(9): e0183774. Published online 2017 Sep 20. doi: 10.1371/journal.pone.0183774

PMCID:: PMC5606929

Abstract Article PDF–7.0M

Select item 54653758.

Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease

Awo Akosua Kesewa Layman, Guoping Deng, Claire E. O'Leary, Samuel Tadros, Rajan M. Thomas, Joseph M. Dybas, Emily K. Moser, Andrew D. Wells, Nicolai M. Doliba, Paula M. Oliver

Nat Commun. 2017; 8: 15677. Published online 2017 Jun 5. doi: 10.1038/ncomms15677

PMCID:: PMC5465375

Abstract Article PDF–1.7M

Select item 53415209.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

Select item 520968710.

Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production

Awo Akosua Kesewa Layman, Stephanie L. Sprout, Dylan Phillips, Paula M. Oliver

Sci Rep. 2017; 7: 39649. Published online 2017 Jan 4. doi: 10.1038/srep39649

PMCID:: PMC5209687

Abstract Article PDF–2.0M

Select item 509529111.

The Nedd4-2/Ndfip1 axis is a negative regulator of IgE-mediated mast cell activation

Kwok Ho Yip, Natasha Kolesnikoff, Nicholas Hauschild, Lisa Biggs, Angel F. Lopez, Stephen J. Galli, Sharad Kumar, Michele A. Grimbaldeston

Nat Commun. 2016; 7: 13198. Published online 2016 Oct 27. doi: 10.1038/ncomms13198

PMCID:: PMC5095291

Abstract Article PDF–2.8M

Select item 483745012.

Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells

Claire E. O'Leary, Christopher R. Riling, Lynn A. Spruce, Hua Ding, Suresh Kumar, Guoping Deng, Yuhong Liu, Steven H. Seeholzer, Paula M. Oliver

Nat Commun. 2016; 7: 11226. Published online 2016 Apr 18. doi: 10.1038/ncomms11226

PMCID:: PMC4837450

Abstract Article PDF–2.3M

Select item 435840313.

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt

Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi

Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115

PMCID:: PMC4358403

Abstract Article PDF–1.4M

Select item 435813414.

Nedd4 Family Interacting Protein 1 (Ndfip1) Is Required for Ubiquitination and Nuclear Trafficking of BRCA1-associated ATM Activator 1 (BRAT1) during the DNA Damage Response

Ley-Hian Low, Yuh-Lit Chow, Yijia Li, Choo-Peng Goh, Ulrich Putz, John Silke, Toru Ouchi, Jason Howitt, Seong-Seng Tan

J Biol Chem. 2015 Mar 13; 290(11): 7141–7150. Published online 2015 Jan 28. doi: 10.1074/jbc.M114.613687

PMCID:: PMC4358134

Abstract Article PDF–2.5M

Select item 392607815.

Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4⁺ T cells

John A. Altin, Stephen R. Daley, Jason Howitt, Helen J. Rickards, Alison K. Batkin, Keisuke Horikawa, Simon J. Prasad, Keats A. Nelms, Sharad Kumar, Lawren C. Wu, Seong-Seng Tan, Matthew C. Cook, Christopher C. Goodnow

Proc Natl Acad Sci U S A. 2014 Feb 11; 111(6): 2067–2074. Published online 2014 Jan 13. doi: 10.1073/pnas.1322739111

PMCID:: PMC3926078

Abstract Article PDF–1.5M

Select item 390545616.

The ubiquitin ligase adaptor Ndfip1 regulates T cell-mediated gastrointestinal inflammation and inflammatory bowel disease susceptibility

HE Ramon, CR Riling, J Bradfield, B Yang, H Hakonarson, PM Oliver

Mucosal Immunol. Author manuscript; available in PMC 2014 Jan 29.

Published in final edited form as: Mucosal Immunol. 2011 May; 4(3): 314–324. Published online 2010 Oct 20. doi: 10.1038/mi.2010.69

PMCID:: PMC3905456

Abstract Article PDF–2.4M

Select item 390173217.

Increased Ndfip1 in the Substantia Nigra of Parkinsonian Brains Is Associated with Elevated Iron Levels

Jason Howitt, Amanda M. Gysbers, Scott Ayton, Francine Carew-Jones, Ulrich Putz, David I. Finkelstein, Glenda M. Halliday, Seong-Seng Tan

PLoS One. 2014; 9(1): e87119. Published online 2014 Jan 24. doi: 10.1371/journal.pone.0087119

PMCID:: PMC3901732

Abstract Article PDF–2.6M

Select item 385312118.

Ndfip1 enforces a requirement for CD28 co-stimulation by limiting IL-2 production

Natalia Ramos-Hernández, Hilda E. Ramon, Allison M. Beal, Ami Laroche, Erin A. Dekleva, Paula M. Oliver

J Immunol. Author manuscript; available in PMC 2014 Aug 15.

Published in final edited form as: J Immunol. 2013 Aug 15; 191(4): 10.4049/jimmunol.1203571. Published online 2013 Jul 12. doi: 10.4049/jimmunol.1203571