PMC Links for GEO Profiles (Select 67732712) - PMC

Dimitri Tchernitchko, Quentin Tavernier, Jérôme Lamoril, Caroline Schmitt, Neila Talbi, Said Lyoumi, Anne-Marie Robreau, Zoubida Karim, Laurent Gouya, Eric Thervet, Alexandre Karras, Hervé Puy, Nicolas Pallet

J Am Soc Nephrol. 2017 Jun; 28(6): 1924–1932. Published online 2016 Dec 28. doi: 10.1681/ASN.2016080918

PMCID:: PMC5461799

Abstract Article

Select item 49579556.

Critical Role of PepT1 in Promoting Colitis-Associated Cancer and Therapeutic Benefits of the Anti-inflammatory PepT1-Mediated Tripeptide KPV in a Murine Model

Emilie Viennois, Sarah A. Ingersoll, Saravanan Ayyadurai, Yuan Zhao, Lixin Wang, Mingzhen Zhang, Moon K. Han, Pallavi Garg, Bo Xiao, Didier Merlin

Cell Mol Gastroenterol Hepatol. 2016 May; 2(3): 340–357. Published online 2016 Feb 16. doi: 10.1016/j.jcmgh.2016.01.006

PMCID:: PMC4957955

Abstract Article PDF–4.6M

Select item 48905337.

PepT1 Expression Helps Maintain Intestinal Homeostasis by Mediating the Differential Expression of miRNAs along the Crypt-Villus Axis

Yuchen Zhang, Emilie Viennois, Mingzhen Zhang, Bo Xiao, Moon Kwon Han, Lewins Walter, Pallavi Garg, Didier Merlin

Sci Rep. 2016; 6: 27119. Published online 2016 Jun 1. doi: 10.1038/srep27119

PMCID:: PMC4890533

Abstract Article PDF–3.8M

Select item 48216918.

Species Differences in the Pharmacokinetics of Cefadroxil as Determined in Wildtype and Humanized PepT1 Mice

Yongjun Hu, David E. Smith

Biochem Pharmacol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Biochem Pharmacol. 2016 May 1; 107: 81–90. Published online 2016 Mar 12. doi: 10.1016/j.bcp.2016.03.008

PMCID:: PMC4821691

Abstract Article PDF–1.4M

Select item 48133809.

The proton‐coupled oligopeptide transporter 1 plays a major role in the intestinal permeability and absorption of 5‐aminolevulinic acid

Yehua Xie, Yongjun Hu, David E. Smith

Br J Pharmacol. 2016 Jan; 173(1): 167–176. Published online 2015 Nov 25. doi: 10.1111/bph.13356

PMCID:: PMC4813380

Abstract Article PDF–831K

Select item 459709110.

Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport

John H. Beale, Joanne L. Parker, Firdaus Samsudin, Anne L. Barrett, Anish Senan, Louise E. Bird, David Scott, Raymond J. Owens, Mark S.P. Sansom, Stephen J. Tucker, David Meredith, Philip W. Fowler, Simon Newstead

Structure. 2015 Oct 6; 23(10): 1889–1899. doi: 10.1016/j.str.2015.07.016

PMCID:: PMC4597091

Abstract Article PDF–2.6M

Select item 448121211.

MicroRNA-193a-3p Reduces Intestinal Inflammation in Response to Microbiota via Down-regulation of Colonic PepT1

Xin Dai, Xi Chen, Qun Chen, Lei Shi, Hongwei Liang, Zhen Zhou, Qian Liu, Wenjing Pang, Dongxia Hou, Cheng Wang, Ke Zen, Yaozong Yuan, Chen-Yu Zhang, Lu Xia

J Biol Chem. 2015 Jun 26; 290(26): 16099–16115. Published online 2015 Apr 30. doi: 10.1074/jbc.M115.659318

PMCID:: PMC4481212

Abstract Article PDF–7.1M

Select item 418667612.

Development and Characterization of a Novel Mouse Line Humanized for the Intestinal Peptide Transporter PEPT1

Yongjun Hu, Yehua Xie, Yuqing Wang, Xiaomei Chen, David E. Smith

Mol Pharm. 2014 Oct 6; 11(10): 3737–3746. Published online 2014 Aug 22. doi: 10.1021/mp500497p

PMCID:: PMC4186676

Abstract Article PDF–1.6M

Select item 415569113.

Bile Acid-regulated Peroxisome Proliferator-activated Receptor-α (PPARα) Activity Underlies Circadian Expression of Intestinal Peptide Absorption Transporter PepT1/Slc15a1

Ayako Okamura, Satoru Koyanagi, Adila Dilxiat, Naoki Kusunose, Jia Jun Chen, Naoya Matsunaga, Shigenobu Shibata, Shigehiro Ohdo

J Biol Chem. 2014 Sep 5; 289(36): 25296–25305. Published online 2014 Jul 11. doi: 10.1074/jbc.M114.577023

PMCID:: PMC4155691

Abstract Article PDF–1.6M

Select item 384410114.

In Vivo Absorption and Disposition of Cefadroxil after Escalating Oral Doses in Wild-Type and PepT1 Knockout Mice

Maria M. Posada, David E. Smith

Pharm Res. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Pharm Res. 2013 Nov; 30(11): 10.1007/s11095-013-1168-3. doi: 10.1007/s11095-013-1168-3

PMCID:: PMC3844101

Abstract Article PDF–1.3M

Select item 382557415.

Oligopeptides stimulate glucagon-like peptide-1 secretion in mice through proton-coupled uptake and the calcium-sensing receptor

Eleftheria Diakogiannaki, Ramona Pais, Gwen Tolhurst, Helen E. Parker, James Horscroft, Beate Rauscher, Tamara Zietek, Hannelore Daniel, Fiona M. Gribble, Frank Reimann

Diabetologia. 2013; 56(12): 2688–2696. Published online 2013 Sep 18. doi: 10.1007/s00125-013-3037-3

PMCID:: PMC3825574

Abstract Article PDF–532K

Select item 378137716.

Impact of Peptide Transporter 1 on the Intestinal Absorption and Pharmacokinetics of Valacyclovir after Oral Dose Escalation in Wild-Type and PepT1 Knockout Mice

Bei Yang, Yongjun Hu, David E. Smith

Drug Metab Dispos. 2013 Oct; 41(10): 1867–1874. Published online 2013 Oct. doi: 10.1124/dmd.113.052597

PMCID:: PMC3781377

Abstract Article PDF–984K

Select item 366883717.

Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice

Inik Chang, Alexa N. Bramall, Amy Greenstein Baynash, Amir Rattner, Dinesh Rakheja, Martin Post, Stephen Joza, Colin McKerlie, Duncan J. Stewart, Roderick R. McInnes, Masashi Yanagisawa

J Clin Invest. 2013 Jun 3; 123(6): 2643–2653. Published online 2013 May 8. doi: 10.1172/JCI66735

PMCID:: PMC3668837

Abstract Article PDF–2.1M

Select item 358348818.

Significance of Peptide Transporter 1 in the Intestinal Permeability of Valacyclovir in Wild-Type and PepT1 Knockout Mice

Bei Yang, David E. Smith

Drug Metab Dispos. 2013 Mar; 41(3): 608–614. Published online 2013 Mar. doi: 10.1124/dmd.112.049239

PMCID:: PMC3583488

Abstract Article PDF–897K

Select item 357241019.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 325817620.

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins

Céline Revenu, Florent Ubelmann, Ilse Hurbain, Fatima El-Marjou, Florent Dingli, Damarys Loew, Delphine Delacour, Jules Gilet, Edith Brot-Laroche, Francisco Rivero, Daniel Louvard, Sylvie Robine

Mol Biol Cell. 2012 Jan 15; 23(2): 324–336. doi: 10.1091/mbc.E11-09-0765