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Select item 107620001.

Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice

Hai Ni, Yinuo Wang, Kai Yao, Ling Wang, Jiancheng Huang, Yongfang Xiao, Hongyao Chen, Bo Liu, Cliff Y. Yang, Jijun Zhao

Nat Commun. 2024; 15: 1. Published online 2024 Jan 2. doi: 10.1038/s41467-023-43650-z

PMCID:: PMC10762000

Abstract Article PDF–2.7M

Select item 107576502.

Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

Dmitri I. Kotov, Ophelia V. Lee, Stefan A. Fattinger, Charlotte A. Langner, Jaresley V. Guillen, Joshua M. Peters, Andres Moon, Eileen M. Burd, Kristen C. Witt, Daniel B. Stetson, David L. Jaye, Bryan D. Bryson, Russell E. Vance

Cell. Author manuscript; available in PMC 2023 Dec 30.

Published in final edited form as: Cell. 2023 Dec 7; 186(25): 5536–5553.e22. Published online 2023 Nov 28. doi: 10.1016/j.cell.2023.11.002

PMCID:: PMC10757650

Abstract Article PDF–3.3M

Select item 89262023.

Differences in neuroinvasion and protective innate immune pathways between encephalitic California Serogroup orthobunyaviruses

Alyssa B. Evans, Clayton W. Winkler, Karin E. Peterson

PLoS Pathog. 2022 Mar; 18(3): e1010384. Published online 2022 Mar 4. doi: 10.1371/journal.ppat.1010384

PMCID:: PMC8926202

Abstract Article PDF–4.0M

Select item 84759504.

UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b

Markus G. Klammer, Omar Dzaye, Thomas Wallach, Christina Krüger, Dorothea Gaessler, Alice Buonfiglioli, Katja Derkow, Helmut Kettenmann, Melanie M. Brinkmann, Seija Lehnardt

Front Immunol. 2021; 12: 715774. Published online 2021 Sep 13. doi: 10.3389/fimmu.2021.715774

PMCID:: PMC8475950

Abstract Article PDF–5.7M

Select item 74159915.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 73384516.

Requirements for the differentiation of innate T-bet^high memory-phenotype CD4⁺ T lymphocytes under steady state

Takeshi Kawabe, Jaeu Yi, Akihisa Kawajiri, Kerry Hilligan, Difeng Fang, Naoto Ishii, Hidehiro Yamane, Jinfang Zhu, Dragana Jankovic, Kwang Soon Kim, Giorgio Trinchieri, Alan Sher

Nat Commun. 2020; 11: 3366. Published online 2020 Jul 6. doi: 10.1038/s41467-020-17136-1

Correction in:: Nat Commun. 2020; 11: 4624.

PMCID:: PMC7338451

Abstract Article PDF–3.5M

Select item 71575247.

Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci

Agata Famà, Angelina Midiri, Giuseppe Mancuso, Carmelo Biondo, Germana Lentini, Roberta Galbo, Maria Miriam Giardina, Giuseppe Valerio De Gaetano, Letizia Romeo, Giuseppe Teti, Concetta Beninati

mBio. 2020 Mar-Apr; 11(2): e00415-20. Published online 2020 Mar 24. doi: 10.1128/mBio.00415-20

PMCID:: PMC7157524

Abstract Article PDF–2.9M

Select item 70780328.

Cross-reactive antigen expressed by B6 splenocytes drives receptor editing and MZ differentiation of IgG2a-reactive AM14 Vκ8 B cells

Kerstin Nündel, Purvi Mande, Stephanie L. Moses, Patricia Busto, Jaime L. Cullen, Madelyn R. Schmidt, Mark J. Shlomchik, Robert T. Woodland, Ann Marshak-Rothstein

J Immunol. Author manuscript; available in PMC 2021 Mar 18.

Published in final edited form as: J Immunol. 2019 Oct 15; 203(8): 2055–2062. doi: 10.4049/jimmunol.1900499

PMCID:: PMC7078032

Abstract Article PDF–2.1M

Select item 69492469.

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

Franziska Herster, Zsofia Bittner, Nathan K. Archer, Sabine Dickhöfer, David Eisel, Tatjana Eigenbrod, Thomas Knorpp, Nicole Schneiderhan-Marra, Markus W. Löffler, Hubert Kalbacher, Tim Vierbuchen, Holger Heine, Lloyd S. Miller, Dominik Hartl, Lukas Freund, Knut Schäkel, Martin Heister, Kamran Ghoreschi, Alexander N. R. Weber

Nat Commun. 2020; 11: 105. Published online 2020 Jan 8. doi: 10.1038/s41467-019-13756-4

PMCID:: PMC6949246

Abstract Article PDF–2.7M

Select item 688814110.

Bone marrow CX3CR1⁺ mononuclear cells relay a systemic microbiota signal to control hematopoietic progenitors in mice

Seungwon Lee, Hyekang Kim, Gihoon You, Young-Min Kim, Seunghun Lee, Viet-Hoan Le, Ohseop Kwon, Sin-Hyeog Im, You-Me Kim, Kwang Soon Kim, Young Chul Sung, Ki Hean Kim, Charles D. Surh, Yunji Park, Seung-Woo Lee

Blood. 2019 Oct 17; 134(16): 1312–1322. Prepublished online 2019 Aug 6. doi: 10.1182/blood.2019000495

PMCID:: PMC6888141

Abstract Article

Select item 685644111.

Unc93b1 recruits Syntenin-1 to dampen TLR7 signaling and prevent autoimmunity

Olivia Majer, Bo Liu, Lieselotte SM Kreuk, Nevan Krogan, Gregory M. Barton

Nature. Author manuscript; available in PMC 2020 Mar 23.

Published in final edited form as: Nature. 2019 Nov; 575(7782): 366–370. Published online 2019 Sep 23. doi: 10.1038/s41586-019-1612-6

PMCID:: PMC6856441

Abstract Article PDF–3.8M

Select item 685643812.

Release from Unc93b1 reinforces the compartmentalized activation of select TLRs

Olivia Majer, Bo Liu, Brian J Woo, Lieselotte SM Kreuk, Erik Van Dis, Gregory M Barton

Nature. Author manuscript; available in PMC 2020 Mar 23.

Published in final edited form as: Nature. 2019 Nov; 575(7782): 371–374. Published online 2019 Sep 23. doi: 10.1038/s41586-019-1611-7

PMCID:: PMC6856438

Abstract Article PDF–3.5M

Select item 673883313.

Unc93b1-Dependent Endosomal Toll-Like Receptor Signaling Regulates Inflammation and Mortality during Coxsackievirus B3 Infection

Erin I. Lafferty, Sean A. Wiltshire, Isabelle Angers, Silvia M. Vidal, Salman T. Qureshi

J Innate Immun. 2015 Apr; 7(3): 315–330. Published online 2015 Feb 11. doi: 10.1159/000369342

PMCID:: PMC6738833

Abstract Article PDF–603K

Select item 670385514.

B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota

Lieselotte SM Kreuk, Meghan A Koch, Leianna C Slayden, Nicholas A Lind, Sophia Chu, Hannah P Savage, Aaron B Kantor, Nicole Baumgarth, Gregory M Barton

eLife. 2019; 8: e47015. Published online 2019 Aug 21. doi: 10.7554/eLife.47015

PMCID:: PMC6703855

Abstract Article PDF–1.9M

Select item 670385315.

TLR induces reorganization of the IgM-BCR complex regulating murine B-1 cell responses to infections

Hannah P Savage, Kathrin Kläsener, Fauna L Smith, Zheng Luo, Michael Reth, Nicole Baumgarth

eLife. 2019; 8: e46997. Published online 2019 Aug 21. doi: 10.7554/eLife.46997

PMCID:: PMC6703853

Abstract Article PDF–4.5M

Select item 656126416.

Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice

Kuan-wen Wang, Xiaoming Zhan, William McAlpine, Zhao Zhang, Jin Huk Choi, Hexin Shi, Takuma Misawa, Tao Yue, Duanwu Zhang, Ying Wang, Sara Ludwig, Jamie Russell, Miao Tang, Xiaohong Li, Anne R. Murray, Eva Marie Y. Moresco, Emre E. Turer, Bruce Beutler

Proc Natl Acad Sci U S A. 2019 Jun 4; 116(23): 11380–11389. Published online 2019 May 16. doi: 10.1073/pnas.1901407116

PMCID:: PMC6561264

Abstract Article PDF–1.4M

Select item 648205117.

The chaperone UNC93B1 regulates toll-like receptor stability independent of endosomal TLR transport

Karin Pelka, Damien Bertheloot, Elisa Reimer, Kshiti Phulphagar, Susanne V. Schmidt, Anette Christ, Rainer Stahl, Nicki Watson, Kensuke Miyake, Nir Hacohen, Albert Haas, Melanie M. Brinkmann, Ann Marshak-Rothstein, Felix Meissner, Eicke Latz

Immunity. Author manuscript; available in PMC 2019 May 15.

Published in final edited form as: Immunity. 2018 May 15; 48(5): 911–922.e7. doi: 10.1016/j.immuni.2018.04.011

PMCID:: PMC6482051

Abstract Article PDF–2.6M

Select item 634003918.

Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 Infection

Kendra A. Bussey, Sripriya Murthy, Elisa Reimer, Baca Chan, Bastian Hatesuer, Klaus Schughart, Britt Glaunsinger, Heiko Adler, Melanie M. Brinkmann

J Virol. 2019 Feb 1; 93(3): e01173-18. Prepublished online 2018 Nov 14. Published online 2019 Jan 17. doi: 10.1128/JVI.01173-18

PMCID:: PMC6340039

Abstract Article PDF–2.2M

Select item 629804019.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 615294120.

A map of Toll-like receptor expression in the intestinal epithelium reveals distinct spatial, cell type-specific, and temporal patterns

April E Price, Kiarash Shamardani, Kyler A Lugo, Jacques Deguine, Allison W Roberts, Bettina L Lee, Gregory M Barton

Immunity. Author manuscript; available in PMC 2019 Sep 18.

Published in final edited form as: Immunity. 2018 Sep 18; 49(3): 560–575.e6. Published online 2018 Aug 28. doi: 10.1016/j.immuni.2018.07.016

PMCID:: PMC6152941

Abstract Article PDF–4.5M

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