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Items: 1 to 20 of 30

1.
Temporal regulation of the Mediator complex during muscle proliferation, differentiation, regeneration, aging, and disease
Dominic W. Kolonay, Kristina M. Sattler, Corinne Strawser, Jill Rafael-Fortney, Maria M. Mihaylova, Katherine E. Miller, Christoph Lepper, Kedryn K. Baskin
Front Cell Dev Biol. 2024; 12: 1331563. Published online 2024 Apr 16. doi: 10.3389/fcell.2024.1331563
PMCID:
PMC11058648
AbstractArticlePDF–3.8M
2.
MED12 Regulates Human Adipose-Derived Stem Cell Adipogenesis and Mediator Kinase Subunit Expression in Murine Adipose Depots
Sree Venigalla, Joseph Straub, Onyekachi Idigo, Caroline Rinderle, Jacqueline M. Stephens, Jamie J. Newman
Stem Cells Dev. March 2022; 31(5-6): 119–131. Published online 2022 Mar 14. doi: 10.1089/scd.2021.0302
PMCID:
PMC9206493
AbstractArticlePDF–1.0M
3.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
4.
Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network
Changming Tan, Siting Zhu, Zee Chen, Canzhao Liu, Yang E. Li, Mason Zhu, Zhiyuan Zhang, Zhiwei Zhang, Lunfeng Zhang, Yusu Gu, Zhengyu Liang, Thomas G. Boyer, Kunfu Ouyang, Sylvia M. Evans, Xi Fang
PLoS Genet. 2021 Sep; 17(9): e1009785. Published online 2021 Sep 10. doi: 10.1371/journal.pgen.1009785
PMCID:
PMC8432849
AbstractArticlePDF–3.4M
5.
Glial-Specific Deletion of Med12 Results in Rapid Hearing Loss via Degradation of the Stria Vascularis
Teng-Wei Huang, Amrita A. Iyer, Jeanne M. Manalo, Junsung Woo, Navish A. Bosquez Huerta, Melissa M. McGovern, Heinrich Schrewe, Fredrick A. Pereira, Andrew K. Groves, Kevin K. Ohlemiller, Benjamin Deneen
J Neurosci. 2021 Aug 25; 41(34): 7171–7181. doi: 10.1523/JNEUROSCI.0070-21.2021
PMCID:
PMC8387121
AbstractArticlePDF–4.2M
6.
Sox10 Cooperates with the Mediator Subunit 12 during Terminal Differentiation of Myelinating Glia
Michael R. Vogl, Simone Reiprich, Melanie Küspert, Thomas Kosian, Heinrich Schrewe, Klaus-Armin Nave, Michael Wegner
J Neurosci. 2013 Apr 10; 33(15): 6679–6690. doi: 10.1523/JNEUROSCI.5178-12.2013
PMCID:
PMC6619079
AbstractArticlePDF–2.3M
7.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
8.
Med12 regulates ovarian steroidogenesis, uterine development and maternal effects in the mammalian egg
Xinye Wang, Priya Mittal, Carlos A Castro, Gabriel Rajkovic, Aleksandar Rajkovic
Biol Reprod. 2017 Dec; 97(6): 822–834. Published online 2017 Nov 8. doi: 10.1093/biolre/iox143
PMCID:
PMC6248388
AbstractArticlePDF–2.8M
9.
MED12 regulates a transcriptional network of calcium-handling genes in the heart
Kedryn K. Baskin, Catherine A. Makarewich, Susan M. DeLeon, Wenduo Ye, Beibei Chen, Nadine Beetz, Heinrich Schrewe, Rhonda Bassel-Duby, Eric N. Olson
JCI Insight. 2017 Jul 20; 2(14): e91920. Published online 2017 Jul 20. doi: 10.1172/jci.insight.91920
PMCID:
PMC5518564
AbstractArticlePDF–3.2M
10.
MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis
Beatriz Aranda-Orgilles, Ricardo Saldaña-Meyer, Eric Wang, Eirini Trompouki, Anne Fassl, Stephanie Lau, Jasper Mullenders, Pedro P. Rocha, Ramya Raviram, María Guillamot, María Sánchez-Díaz, Kun Wang, Clarisse Kayembe, Nan Zhang, Leonela Amoasii, Avik Choudhuri, Jane A. Skok, Markus Schober, Danny Reinberg, Piotr Sicinski, Heinrich Schrewe, Aristotelis Tsirigos, Leonard I. Zon, Iannis Aifantis
Cell Stem Cell. Author manuscript; available in PMC 2017 Jan 26.
Published in final edited form as: Cell Stem Cell. 2016 Dec 1; 19(6): 784–799. Published online 2016 Aug 25. doi: 10.1016/j.stem.2016.08.004
PMCID:
PMC5268820
AbstractArticlePDF–1.7M
11.
Dual role of Med12 in PRC1-dependent gene repression and ncRNA-mediated transcriptional activation
Thaleia Papadopoulou, Aysegül Kaymak, Sergi Sayols, Holger Richly
Cell Cycle. 2016; 15(11): 1479–1493. Published online 2016 Apr 20. doi: 10.1080/15384101.2016.1175797
PMCID:
PMC4934080
AbstractArticlePDF–1.6M
12.
Mediator subunit Med12 contributes to the maintenance of neural stem cell identity
Nam Hee Kim, Carolina B. Livi, P. Renee Yew, Thomas G. Boyer
BMC Dev Biol. 2016; 16: 17. Published online 2016 May 17. doi: 10.1186/s12861-016-0114-0
PMCID:
PMC4869265
AbstractArticlePDF–3.4M
13.
Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination
Anne-Sophie Thomas-Claudepierre, Isabelle Robert, Pedro P. Rocha, Ramya Raviram, Ebe Schiavo, Vincent Heyer, Richard Bonneau, Vincent M. Luo, Janardan K. Reddy, Tilman Borggrefe, Jane A. Skok, Bernardo Reina-San-Martin
J Exp Med. 2016 Mar 7; 213(3): 303–312. doi: 10.1084/jem.20141967
PMCID:
PMC4813673
AbstractArticlePDF–2.2M
14.
Med12 gain-of-function mutation causes leiomyomas and genomic instability
Priya Mittal, Yong-hyun Shin, Svetlana A. Yatsenko, Carlos A. Castro, Urvashi Surti, Aleksandar Rajkovic
J Clin Invest. 2015 Aug 3; 125(8): 3280–3284. Published online 2015 Jul 20. doi: 10.1172/JCI81534
PMCID:
PMC4563761
AbstractArticlePDF–1.2M
15.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
16.
Dynamics of Mitochondrial DNA Nucleoids Regulated by Mitochondrial Fission Is Essential for Maintenance of Homogeneously Active Mitochondria during Neonatal Heart Development
Takaya Ishihara, Reiko Ban-Ishihara, Maki Maeda, Yui Matsunaga, Ayaka Ichimura, Sachiko Kyogoku, Hiroki Aoki, Shun Katada, Kazuto Nakada, Masatoshi Nomura, Noboru Mizushima, Katsuyoshi Mihara, Naotada Ishihara
Mol Cell Biol. 2015 Jan; 35(1): 211–223. Prepublished online 2014 Oct 27. Published online 2014 Dec 9. doi: 10.1128/MCB.01054-14
PMCID:
PMC4295379
AbstractArticlePDF–7.0M
17.
Cyclin C is a haploinsufficient tumor suppressor
Na Li, Anne Fassl, Joel Chick, Hiroyuki Inuzuka, Xiaoyu Li, Marc R. Mansour, Lijun Liu, Haizhen Wang, Bryan King, Shavali Shaik, Alejandro Gutierrez, Alban Ordureau, Tobias Otto, Taras Kreslavsky, Lukas Baitsch, Leah Bury, Clifford A. Meyer, Nan Ke, Kristin A. Mulry, Michael J. Kluk, Moni Roy, Sunkyu Kim, Xiaowu Zhang, Yan Geng, Agnieszka Zagozdzon, Sarah Jenkinson, Rosemary E. Gale, David C. Linch, Jean J. Zhao, Charles G. Mullighan, J. Wade Harper, Jon C. Aster, Iannis Aifantis, Harald von Boehmer, Steven P. Gygi, Wenyi Wei, A. Thomas Look, Piotr Sicinski
Nat Cell Biol. Author manuscript; available in PMC 2015 May 1.
Published in final edited form as: Nat Cell Biol. 2014 Nov; 16(11): 1080–1091. Published online 2014 Oct 26. doi: 10.1038/ncb3046
PMCID:
PMC4235773
AbstractArticlePDF–4.3M
18.
MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling
Sidong Huang, Michael Hölzel, Theo Knijnenburg, Andreas Schlicker, Paul Roepman, Ultan McDermott, Mathew Garnett, Wipawadee Grernrum, Chong Sun, Anirudh Prahallad, Floris H. Groenendijk, Lorenza Mittempergher, Wouter Nijkamp, Jacques Neefjes, Ramon Salazar, Peter ten Dijke, Hidetaka Uramoto, Fumihiro Tanaka, Roderick L. Beijersbergen, Lodewyk F.A. Wessels, René Bernards
Cell. Author manuscript; available in PMC 2013 Jun 5.
Published in final edited form as: Cell. 2012 Nov 21; 151(5): 937–950. doi: 10.1016/j.cell.2012.10.035
PMCID:
PMC3672971
AbstractArticlePDF–5.8M
19.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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